Functional Information from GO Data
Chain | GOid | namespace | contents |
Q | 0003924 | molecular_function | GTPase activity |
Q | 0005525 | molecular_function | GTP binding |
Q | 0007165 | biological_process | signal transduction |
Q | 0016020 | cellular_component | membrane |
R | 0003924 | molecular_function | GTPase activity |
R | 0005525 | molecular_function | GTP binding |
R | 0007165 | biological_process | signal transduction |
R | 0016020 | cellular_component | membrane |
S | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
S | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG Q 1002 |
Chain | Residue |
Q | SER17 |
Q | THR35 |
Q | GTP1001 |
Q | HOH1008 |
Q | HOH1011 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 R 1003 |
Chain | Residue |
R | SER17 |
R | GLY59 |
R | GLU62 |
R | HOH1074 |
R | GLY13 |
R | VAL14 |
R | GLY15 |
R | LYS16 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE PO4 S 1047 |
Chain | Residue |
S | HOH127 |
S | HOH363 |
S | ARG625 |
S | HIS695 |
S | HIS699 |
S | HIS700 |
site_id | AC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PO4 S 1048 |
Chain | Residue |
R | GLU63 |
R | SER127 |
R | ARG128 |
R | GLN131 |
R | HOH1028 |
S | HOH372 |
S | HOH384 |
S | LYS814 |
S | GLU815 |
S | ARG826 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE PO4 S 1049 |
Chain | Residue |
S | HOH115 |
S | ARG660 |
S | TYR709 |
S | GLU716 |
S | HIS951 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PO4 Q 1007 |
Chain | Residue |
Q | GLU153 |
Q | ASP154 |
Q | TYR157 |
Q | ARG161 |
site_id | AC7 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE GTP Q 1001 |
Chain | Residue |
Q | GLY12 |
Q | GLY13 |
Q | VAL14 |
Q | GLY15 |
Q | LYS16 |
Q | SER17 |
Q | ALA18 |
Q | PHE28 |
Q | VAL29 |
Q | ASP30 |
Q | TYR32 |
Q | PRO34 |
Q | THR35 |
Q | GLY60 |
Q | GLU62 |
Q | ASN116 |
Q | LYS117 |
Q | ASP119 |
Q | LEU120 |
Q | SER145 |
Q | ALA146 |
Q | LYS147 |
Q | MG1002 |
Q | HOH1008 |
Q | HOH1011 |
Q | HOH1019 |
Functional Information from PROSITE/UniProt
site_id | PS00720 |
Number of Residues | 34 |
Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
Chain | Residue | Details |
S | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
Q | GLY13 | |
R | SER145 | |
Q | VAL29 | |
Q | GLY59 | |
Q | ASN116 | |
Q | SER145 | |
R | GLY13 | |
R | VAL29 | |
R | GLY59 | |
R | ASN116 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: N-acetylmethionine; in GTPase HRas; alternate => ECO:0000269|Ref.12 |
Chain | Residue | Details |
Q | MET1 | |
R | MET1 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: N-acetylthreonine; in GTPase HRas, N-terminally processed => ECO:0000269|Ref.12 |
Chain | Residue | Details |
Q | THR2 | |
R | THR2 | |
Chain | Residue | Details |
Q | CYS118 | |
R | CYS118 | |
Chain | Residue | Details |
Q | THR35 | |
R | THR35 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
Q | GLN61 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
R | GLN61 | |