5MIM

Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (1.9 Å)

Cell axes132.204132.204155.727
Cell angles90.0090.00120.00
SpacegroupP 65 2 2
Resolution limits41.69 - 1.90
the highest resolution shell value1.930 - 1.900
R-factor0.1656
R-work0.16470
the highest resolution shell value0.253
R-free0.18380
the highest resolution shell value0.292
RMSD bond length0.007
RMSD bond angle1.070

Data Collection Statistics

Resolution limits46.12 - 1.90
the highest resolution shell value -
Number of reflections63025
Rmerge_l_obs0.131
the highest resolution shell value0.791
Completeness99.2
Redundancy4.9
the highest resolution shell value4.8

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, SITTING DROP293.15

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*