5HXB
Cereblon in complex with DDB1, CC-885, and GSPT1
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ALS BEAMLINE 5.0.2 |
Synchrotron site | ALS |
Beamline | 5.0.2 |
Temperature [K] | 100 |
Detector technology | CCD |
Collection date | 2015-07-17 |
Detector | ADSC QUANTUM 315r |
Wavelength(s) | 1.0 |
Spacegroup name | P 1 2 1 |
Unit cell lengths | 156.747, 111.522, 175.057 |
Unit cell angles | 90.00, 95.81, 90.00 |
Refinement procedure
Data quality characteristics
Overall | Outer shell | |
Low resolution limit [Å] | 50.000 | 3.660 |
High resolution limit [Å] | 3.600 | 3.600 |
Rmerge | 0.198 | 0.796 |
Number of reflections | 66582 | |
<I/σ(I)> | 10.6 | 2.1 |
Completeness [%] | 94.6 | 93.9 |
Redundancy | 4.8 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, SITTING DROP | 280 | 200mM Sodium Citrate, Tris pH 8.5, 18% PEG 3350 |