5GRN

Crystal structure of PDGFRA in Complex with WQ-C-159

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SSRF BEAMLINE BL19U1
Synchrotron site	SSRF
Beamline	BL19U1
Temperature [K]	100
Detector technology	PIXEL
Collection date	2016-07-01
Detector	DECTRIS PILATUS3 6M
Wavelength(s)	0.97853
Spacegroup name	P 21 21 21
Unit cell lengths	48.776, 49.372, 108.696
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	44.952 - 1.770
R-factor	0.1581
Rwork	0.157
R-free	0.17930
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	5k5x
RMSD bond length	0.012
RMSD bond angle	1.381
Data reduction software	DENZO
Data scaling software	HKL-3000
Phasing software	PHASER
Refinement software	PHENIX (1.8.4_1496)

Data quality characteristics

	Overall
Low resolution limit [Å]	50.000
High resolution limit [Å]	1.750
Number of reflections	26385
<I/σ(I)>	41.6
Completeness [%]	96.8
Redundancy	12.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		293	0.2M KCl, 20% PEG 3350, pH 7.0