5GRN

Crystal structure of PDGFRA in Complex with WQ-C-159

Summary for 5GRN

• Entry DOI: 10.2210/pdb5grn/pdb
• Descriptor: Platelet-derived growth factor receptor alpha, N-[2-(dimethylamino)ethyl]-N-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]pyridine-3-carboxamide, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: pdgfra, wq-c-159, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Single- pass type I membrane protein : P16234
• Total number of polymer chains: 1
• Total formula weight: 41281.78

Authors

Yan, X.E.,Yun, C.H. (deposition date: 2016-08-11, release date: 2017-08-16, Last modification date: 2023-11-08)

• Primary citation: Yan, X.E.,Yun, C.H.; Crystal Structure of PDGFRA in Complex with WQ-C-159; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.77 Å)