7EUA
 
 | | X-ray crystal structure of a Monellin deletion construct carrying the P93A mutation | | Descriptor: | Monellin, SULFATE ION | | Authors: | Manjula, R, Bhatia, S, Jayant, B, Ramaswamy, S, Gosavi, S. | | Deposit date: | 2021-05-16 | | Release date: | 2021-08-11 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | X-ray crystal structure of a Monellin deletion construct carrying the P93A mutation
To Be Published
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7KJM
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7KJN
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7QF6
 | | N(5)-hydroxyornithine:cis-anhydromevalonyl coenzyme A-N(5)-transacylase sidF | | Descriptor: | GLYCEROL, N(5)-hydroxyornithine:cis-anhydromevalonyl coenzyme A-N(5)-transacylase sidF, POTASSIUM ION, ... | | Authors: | Poonsiri, T, Demitri, N, Stefano, B. | | Deposit date: | 2021-12-03 | | Release date: | 2022-12-14 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | SidF, a dual substrate N5-acetyl-N5-hydroxy-L-ornithine transacetylase involved in Aspergillus fumigatus siderophore biosynthesis.
J Struct Biol X, 11, 2025
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7Y8J
 | | 3D1 in complex with 6-mer HR1 peptide from SARS-CoV-2 | | Descriptor: | Spike protein S2', heavy chain of 3D1, light chain of 3D1 | | Authors: | Lei, Y. | | Deposit date: | 2022-06-24 | | Release date: | 2023-07-12 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (1.03 Å) | | Cite: | A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses.
Nat Commun, 16, 2025
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7YD3
 | | Single-chain variable fragment of app 3D1 antibody | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Yan, L, Yang, G. | | Deposit date: | 2022-07-03 | | Release date: | 2023-07-05 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses
Nat Commun, 16, 2025
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7YI6
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8B4T
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8B5F
 | | Human cathepsin B in complex with the carbamate inhibitor 31 | | Descriptor: | (2S)-2-[[(2S)-2-[[3-chloranyl-4-[[3-phenyl-2-(phenylmethyl)propanoyl]amino]phenoxy]carbonylamino]-3-cyclohexyl-propanoyl]amino]-3-phenyl-propanoic acid, 1,2-ETHANEDIOL, Cathepsin B | | Authors: | Rubesova, P, Guetschow, M, Mares, M. | | Deposit date: | 2022-09-22 | | Release date: | 2023-10-04 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Redirecting the Peptide Cleavage Causes Protease Inactivation.
Angew.Chem.Int.Ed.Engl., 64, 2025
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8E6O
 | | Crystal structure of human GCN5 histone acetyltransferase domain | | Descriptor: | Histone acetyltransferase KAT2A, S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate | | Authors: | Lu, X.T, Tao, Y.J. | | Deposit date: | 2022-08-23 | | Release date: | 2024-02-28 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion.
Cell Metab., 37, 2025
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8G4A
 | | Human ARNT PAS-B complexed with KG-548 small molecule | | Descriptor: | 5-[3,5-bis(trifluoromethyl)phenyl]-2H-tetrazole, Aryl hydrocarbon receptor nuclear translocator | | Authors: | Xu, X, Isiorho, E.A, Pimentel Marcelino, L, Gardner, K.H. | | Deposit date: | 2023-02-08 | | Release date: | 2024-02-14 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids
Biorxiv, 2023
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8QH5
 | | CryoEM structure of UVSSA(VHS)-CSA-DDB1-DDA1 | | Descriptor: | DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... | | Authors: | Lee, S.-H, Sixma, T.K. | | Deposit date: | 2023-09-06 | | Release date: | 2024-08-14 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | The small CRL4 CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.
Nat Commun, 15, 2024
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8RQZ
 | | Crystal structure of Molybdenum bispyranopterin guanine dinucleotide formate dehydrogenases ForCE1 from Bacillus subtilis | | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Cherrier, M.V, Arnoux, P, Martin, L, Nicolet, Y, Schoehn, G, Legrand, P, Broc, M, Seduk, F, Brasseur, G, Arias-Cartin, R, Magalon, A, Walburger, A, Uzel, A, Guigliarelli, B, Grimaldi, S, Pierrel, F, Mate, M. | | Deposit date: | 2024-01-22 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (2.694 Å) | | Cite: | A scaffold for quinone channeling between membrane and soluble bacterial oxidoreductases
Nat.Struct.Mol.Biol., 2025
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8RR0
 | | CryoEM structure of Molybdenum bispyranopterin guanine dinucleotide formate dehydrogenases ForCE1 from Bacillus subtilis | | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, HEPTANOIC ACID, ... | | Authors: | Cherrier, M.V, Arnoux, P, Martin, L, Nicolet, Y, Schoehn, G, Legrand, P, Broc, M, Seduk, F, Brasseur, G, Arias-Cartin, R, Magalon, A, Walburger, A, Uzel, A, Guigliarelli, B, Grimaldi, S, Pierrel, F, Mate, M. | | Deposit date: | 2024-01-22 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | A scaffold for quinone channeling between membrane and soluble bacterial oxidoreductases
Nat.Struct.Mol.Biol., 2025
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8RV3
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8RVG
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8RVH
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8RVI
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8RVU
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8RVV
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8RVY
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8RWN
 | | CryoEM structure of the Hdr(ABC)2 subunits of the Elp-Hdr complex of Methanothermobacter marburgensis | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit A, H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit B, ... | | Authors: | San Segundo-Acosta, P, Murphy, B.J. | | Deposit date: | 2024-02-05 | | Release date: | 2025-05-14 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (1.85 Å) | | Cite: | Electron flow in hydrogenotrophic methanogens under nickel limitation.
Nature, 644, 2025
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8TVT
 | | Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2 | | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | | Authors: | Cygler, M, Boniecki, M.T. | | Deposit date: | 2023-08-18 | | Release date: | 2024-09-11 | | Last modified: | 2025-08-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | D-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1.
Nat Metab, 2025
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8U1P
 | | Local refinement of Plasmodium falciparum gametocyte surface protein Pfs48/45 Domains 1 and 2 in complex with neutralizing antibodies | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, ... | | Authors: | Kucharska, I, Hailemariam, S, Ivanochko, D, Rubinstein, J, Julien, J.P. | | Deposit date: | 2023-09-01 | | Release date: | 2025-03-12 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural elucidation of full-length Pfs48/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual.
Nat.Struct.Mol.Biol., 32, 2025
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8URM
 | | E. coli 70S ribosome with unmodified tRNAPro(GGG) bound to slippery P-site CCC-C codon and tRNAVal(UAC) in the A site | | Descriptor: | 13S ribosomal RNA, 16S ribosomal RNA, 30S ribosomal protein S11, ... | | Authors: | Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. | | Deposit date: | 2023-10-26 | | Release date: | 2025-07-09 | | Last modified: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Nat Commun, 16, 2025
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