7RQC
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MFI-tripeptidyl-tRNA analog ACCA-IFM at 2.50A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | 登録日 | 2021-08-06 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
|
|
7RQD
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | 登録日 | 2021-08-06 | 公開日 | 2022-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
|
|
7RQE
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MAI-tripeptidyl-tRNA analog ACCA-IAM, and chloramphenicol at 2.40A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | 登録日 | 2021-08-06 | 公開日 | 2022-01-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
|
|
7RR5
| Structure of ribosomal complex bound with Rbg1/Tma46 | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Zeng, F, Li, X, Pires-Alves, M, Chen, X, Hawk, C.W, Jin, H. | 登録日 | 2021-08-09 | 公開日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells. Cell Rep, 37, 2021
|
|
7RRO
| Structure of the 48-nm repeat doublet microtubule from bovine tracheal cilia | 分子名称: | Armadillo repeat containing 4, Chromosome 3 C1orf194 homolog, Cilia and flagella associated protein 161, ... | 著者 | Gui, M, Anderson, J.R, Botsch, J.J, Meleppattu, S, Singh, S.K, Zhang, Q, Brown, A. | 登録日 | 2021-08-10 | 公開日 | 2021-10-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | De novo identification of mammalian ciliary motility proteins using cryo-EM. Cell, 184, 2021
|
|
7RS5
| Cryo-EM structure of Kip3 (AMPPNP) bound to Taxol-Stabilized Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R. | 登録日 | 2021-08-10 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization Biorxiv, 2021
|
|
7RS6
| Cryo-EM structure of Kip3 (AMPPNP) bound to GMPCPP-Stabilized Microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R. | 登録日 | 2021-08-11 | 公開日 | 2022-08-17 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization Biorxiv, 2024
|
|
7RSX
| HIV-1 gp120 complex with CJF-III-049-S | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3S)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
|
|
7RSY
| HIV-1 gp120 complex with CJF-III-049-R | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 Clade C1086, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3R)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
|
|
7RSZ
| HIV-1 gp120 complex with CJF-II-204 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 Clade C1086, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3R)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide, ... | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
|
|
7RTE
| X-ray structure of wild type RBPJ-L3MBTL3-DNA complex | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | 登録日 | 2021-08-13 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3. Nucleic Acids Res., 50, 2022
|
|
7RTI
| X-ray structure of RBPJ-L3MBTL3(dT62)-DNA complex | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | 登録日 | 2021-08-13 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3. Nucleic Acids Res., 50, 2022
|
|
7RWL
| Envelope-associated Adeno-associated virus serotype 2 | 分子名称: | Capsid protein VP1 | 著者 | Hull, J.A, Mietzsch, M, Chipman, P, Strugatsky, D, McKenna, R. | 登録日 | 2021-08-20 | 公開日 | 2021-10-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural characterization of an envelope-associated adeno-associated virus type 2 capsid. Virology, 565, 2021
|
|
7RWT
| Adeno-associated virus type 2 | 分子名称: | Capsid protein VP1 | 著者 | Hull, J.A, Mietzsch, M, Chipman, P, Strugatsky, D, McKenna, R. | 登録日 | 2021-08-20 | 公開日 | 2021-10-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | Structural characterization of an envelope-associated adeno-associated virus type 2 capsid. Virology, 565, 2021
|
|
7RXY
| Hen egg-white lysozyme with ionic liquid ethylammonium nitrate 5 mol% | 分子名称: | Lysozyme C, NITRATE ION | 著者 | Han, Q, Darmanin, C, Smith, K, Drummond, C, Greaves, T. | 登録日 | 2021-08-24 | 公開日 | 2023-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids. J Colloid Interface Sci, 650, 2023
|
|
7RY5
| Cellular Retinoic Acid Binding Protein II with Bound Inhibitor 4-[6-({4-[(fluorosulfonyl)oxy]phenyl}ethynyl)-4,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl]-4-oxobutanoic acid | 分子名称: | 4-[6-({4-[(fluorosulfonyl)oxy]phenyl}ethynyl)-4,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl]-4-oxobutanoic acid, Cellular retinoic acid-binding protein 2 | 著者 | Kimmel, B.R, Mrksich, M. | 登録日 | 2021-08-24 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly. Chemistry, 27, 2021
|
|
7RYD
| Hen egg-white lysozyme with ionic liquid butylammonium nitrate 1 mol% | 分子名称: | Lysozyme C, NITRATE ION | 著者 | Han, Q, Darmanin, C, Smith, K, Drummond, C, Greaves, T. | 登録日 | 2021-08-25 | 公開日 | 2023-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids. J Colloid Interface Sci, 650, 2023
|
|
7RYF
| A. baumannii Ribosome-TP-6076 complex: P-site tRNA 70S | 分子名称: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | 著者 | Morgan, C.E, Yu, E.W. | 登録日 | 2021-08-25 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
|
|
7RYG
| A. baumannii Ribosome-TP-6076 complex: E-site tRNA 70S | 分子名称: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | 著者 | Morgan, C.E, Yu, E.W. | 登録日 | 2021-08-25 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
|
|
7RYH
| A. baumannii Ribosome-TP-6076 complex: Empty 70S | 分子名称: | (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 16S Ribosomal RNA, 23S ribosomal RNA, ... | 著者 | Morgan, C.E, Yu, E.W. | 登録日 | 2021-08-25 | 公開日 | 2022-02-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii. Mbio, 13, 2022
|
|
7RYJ
| |
7RYK
| Hen egg-white lysozyme with ionic liquid ethanolammonium nitrate 1 mol% | 分子名称: | Lysozyme C, NITRATE ION | 著者 | Han, Q, Darmanin, C, Smith, K, Drummond, C, Greaves, T. | 登録日 | 2021-08-25 | 公開日 | 2023-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids. J Colloid Interface Sci, 650, 2023
|
|
7RZ0
| Hen egg-white lysozyme with ionic liquid ethanolammonium formate 6.7 mol% | 分子名称: | ETHANOLAMINE, FORMIC ACID, Lysozyme C | 著者 | Han, Q, Darmanin, C, Drummond, C, Greaves, T. | 登録日 | 2021-08-27 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids. J Colloid Interface Sci, 650, 2023
|
|
7RZ2
| Hen egg-white lysozyme with ionic liquid ethanolammonium formate 4 mol% | 分子名称: | ETHANOLAMINE, FORMIC ACID, Lysozyme C | 著者 | Han, Q, Darmanin, C, Drummond, C, Greaves, T. | 登録日 | 2021-08-27 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Probing ion-binding at a protein interface: Modulation of protein properties by ionic liquids. J Colloid Interface Sci, 650, 2023
|
|
7S0P
| Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine | 分子名称: | Coagulation factor VIII, PHOSPHOSERINE | 著者 | Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. | 登録日 | 2021-08-30 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII. Front Mol Biosci, 9, 2022
|
|