7PNX
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation a | 分子名称: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PNY
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation b | 分子名称: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PNZ
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation c | 分子名称: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PO0
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and IF3 | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PO1
| Initiation complex of human mitochondrial ribosome small subunit with IF3 | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PO2
| Initiation complex of human mitochondrial ribosome small subunit with IF2, fMet-tRNAMet and mRNA | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PO3
| Human mitochondrial ribosome small subunit | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7PO4
| Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP) | 分子名称: | 16SrRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | 登録日 | 2021-09-08 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
|
|
7POX
| TNKS2 in complex with OM-1700, treated with H2O2 | 分子名称: | N-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]pyridine-2-carboxamide, Poly [ADP-ribose] polymerase tankyrase-2 | 著者 | Sowa, S.T, Lehtio, L. | 登録日 | 2021-09-10 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The zinc-binding motif in tankyrases is required for the structural integrity of the catalytic ADP-ribosyltransferase domain. Open Biology, 12, 2022
|
|
7PP1
| |
7PPX
| ATAD2 in complex with FragLite3 | 分子名称: | 1,2-ETHANEDIOL, 4-bromanyl-1,2-oxazole, ATPase family AAA domain-containing protein 2, ... | 著者 | Turberville, S, Martin, M.P, Hope, I, Wood, D.J, Ng, Y.M, Heath, R, Endicott, J.A, Noble, M.E.M. | 登録日 | 2021-09-15 | 公開日 | 2022-09-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
|
|
7PQ2
| Crystal Structure of the Ring Nuclease 0811 from Sulfolobus islandicus (Sis0811) in its apo form | 分子名称: | CRISPR-associated protein, APE2256 family, CRISPR Ring Nuclease | 著者 | Molina, R, Jensen, A.L.G, Marchena-Hurtado, J, Lopez-Mendez, B, Stella, S, Montoya, G. | 登録日 | 2021-09-16 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases. Nucleic Acids Res., 49, 2021
|
|
7PQ3
| Crystal Structure of the Ring Nuclease 0811 from Sulfolobus islandicus (Sis0811) in complex with its post-catalytic reaction product | 分子名称: | 3'-O-[(R)-{[(2S,3aS,4S,6S,6aS)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]adenosine, CRISPR-associated protein, APE2256 family | 著者 | Molina, R, Jensen, A.L.G, Marchena-Hurtado, J, Lopez-Mendez, B, Stella, S, Montoya, G. | 登録日 | 2021-09-16 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases. Nucleic Acids Res., 49, 2021
|
|
7PQ6
| Crystal Structure of the Ring Nuclease 0811 mutant-S12A from Sulfolobus islandicus (Sis0811) | 分子名称: | CRISPR-associated protein, APE2256 family | 著者 | Molina, R, Jensen, A.L.G, Marchena-Hurtado, J, Lopez-Mendez, B, Stella, S, Montoya, G. | 登録日 | 2021-09-16 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases. Nucleic Acids Res., 49, 2021
|
|
7PQ9
| Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Vivoli Vega, M, Isupov, M.N, Harmer, N. | 登録日 | 2021-09-16 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
|
|
7PQA
| Crystal Structure of the Ring Nuclease 0811 mutant-S12G/K169G from Sulfolobus islandicus (Sis0811) | 分子名称: | CRISPR-associated protein, APE2256 family | 著者 | Molina, R, Jensen, A.L.G, Marchena-Hurtado, J, Lopez-Mendez, B, Stella, S, Montoya, G. | 登録日 | 2021-09-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases. Nucleic Acids Res., 49, 2021
|
|
7PQD
| Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 A: the structural basis for dimerisation | 分子名称: | (2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | 著者 | Qian, P, Hunter, C.N. | 登録日 | 2021-09-17 | 公開日 | 2021-11-24 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 angstrom : the structural basis for dimerisation. Biochem.J., 478, 2021
|
|
7PQH
| Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains). | 分子名称: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8 | 著者 | Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R. | 登録日 | 2021-09-17 | 公開日 | 2023-01-18 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | EGOC inhibits TOROID polymerization by structurally activating TORC1. Nat.Struct.Mol.Biol., 30, 2023
|
|
7PQN
| Catalytic fragment of MASP-2 in complex with ecotin | 分子名称: | Ecotin, GLYCEROL, Mannan-binding lectin serine protease 2 A chain, ... | 著者 | Harmat, V, Fodor, K, Heja, D. | 登録日 | 2021-09-17 | 公開日 | 2022-05-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.40001520992 Å) | 主引用文献 | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
|
|
7PQO
| Catalytic fragment of MASP-1 in complex with P1 site mutant ecotin | 分子名称: | Ecotin, GLYCEROL, Mannan-binding lectin serine protease 1, ... | 著者 | Harmat, V, Fodor, K, Heja, D. | 登録日 | 2021-09-17 | 公開日 | 2022-05-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | 主引用文献 | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
|
|
7PR6
| Crystal structure of E. coli beta-glucuronidase in complex with covalent inhibitor ME727 | 分子名称: | (2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase | 著者 | Wu, L, Armstrong, Z, Davies, G.J. | 登録日 | 2021-09-20 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7PRG
| Joint X-ray/neutron room temperature structure of perdeuterated LecB lectin in complex with perdeuterated fucose | 分子名称: | CALCIUM ION, Fucose-binding lectin, SULFATE ION, ... | 著者 | Gajdos, L, Blakeley, M.P, Haertlein, M, Forsyth, T.V, Devos, J.M, Imberty, A. | 登録日 | 2021-09-21 | 公開日 | 2022-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.85 Å), X-RAY DIFFRACTION | 主引用文献 | Neutron crystallography reveals mechanisms used by Pseudomonas aeruginosa for host-cell binding. Nat Commun, 13, 2022
|
|
7PRI
| Carbonic Anhydrase from Schistosoma Mansoni in complex with clorsulon | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-azanyl-6-[1,2,2-tris(chloranyl)ethenyl]benzene-1,3-disulfonamide, Carbonic anhydrase, ... | 著者 | Angeli, A, Ferraroni, M. | 登録日 | 2021-09-21 | 公開日 | 2022-10-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.679 Å) | 主引用文献 | Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7PRP
| |
7PRS
| |