7PRI

Carbonic Anhydrase from Schistosoma Mansoni in complex with clorsulon

This is a non-PDB format compatible entry.

Summary for 7PRI

• Entry DOI: 10.2210/pdb7pri/pdb
• Descriptor: Carbonic anhydrase, ZINC ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: inhibitor, sulfonamide, schistosoma, schistosomiasis, lyase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 2
• Total formula weight: 66310.43

Authors

Angeli, A.,Ferraroni, M. (deposition date: 2021-09-21, release date: 2022-10-05, Last modification date: 2024-02-07)

• Primary citation: Ferraroni, M.,Angeli, A.,Carradori, S.,Supuran, C.T.; Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies.; Acta Crystallogr D Struct Biol, 78:321-327, 2022; PubMed: 35234146; DOI: 10.1107/S2059798322000079

Experimental method

X-RAY DIFFRACTION (1.679 Å)