신종 코로나바이러스 특집 콘텐츠

이 페이지는 다른 언어로도 제공됩니다: English 日本語简体中文繁體中文

코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.

Created: 2020-09-03 (last edited: more than 1 year ago)

전체 엔트리 (5197)대표구조 (2266)최신 엔트리 (44)

9CPY

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies C11-0860 and CC12.3
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, C11-0860 Fab heavy chain, C11-0860 Fab light chain, ...
Authors:	Feng, Z, Wilson, I.A.
Deposit date:	2024-07-18
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (3.1 Å)
Cite:	Structures of CR3022-like antibodies To Be Published

9P0F

Crystal Structure of the C-terminal Cytoplasmic Domain of nsp4 from SARS-CoV-2
Descriptor:	Non-structural protein 4, SODIUM ION
Authors:	Minasov, G, Shuvalova, L, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2025-06-06
Release date:	2025-06-25
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Crystal Structure of the C-terminal Cytoplasmic Domain of nsp4 from SARS-CoV-2 To Be Published

9CFE

Cryo-EM Local Refinement of Antibody 19-77 in complex with prefusion SARS-CoV-2 Spike glycoprotein RBD
Descriptor:	Spike protein S1, heavy chain, light chain
Authors:	Casner, R.G, Shapiro, L.
Deposit date:	2024-06-27
Release date:	2025-07-02
Method:	ELECTRON MICROSCOPY (3.03 Å)
Cite:	More SARS-CoV-2 antibodies To Be Published

9CFF

Cryo-EM Refinement of Antibody 19-77 in complex with SARS-CoV-2 HK.3 RBD
Descriptor:	Spike protein S1, heavy chain, light chain
Authors:	Casner, R.G, Shapiro, L.
Deposit date:	2024-06-27
Release date:	2025-07-02
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	More SARS-CoV-2 antibodies To Be Published

9CFG

Cryo-EM Refinement of Antibody 19-77 R71V in complex with SARS-CoV-2 HK.3 RBD
Descriptor:	Spike protein S1, heavy chain, light chain
Authors:	Casner, R.G, Shapiro, L.
Deposit date:	2024-06-27
Release date:	2025-07-02
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	More SARS-CoV-2 antibodies To Be Published

9CFH

Cryo-EM Refinement of Antibody 19-77 R71V in complex with SARS-CoV-2 JD.1.1 RBD
Descriptor:	Spike protein S1, heavy chain, light chain
Authors:	Casner, R.G, Shapiro, L.
Deposit date:	2024-06-27
Release date:	2025-07-02
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	More SARS-CoV-2 antibodies To Be Published

9J8T

Crystal structure of SARS-CoV-2 main protease in complex with Mp-4L2
Descriptor:	3C-like proteinase nsp5, TYR-DSG-DLE-DPN-DGN-ARG-DTH-DAS-DTR-DTH-ALO-DGN-DTY-CCJ-GLY-NH2
Authors:	Shi, Y.S, Yang, J.Y, Wang, M.W.
Deposit date:	2024-08-21
Release date:	2025-07-02
Method:	X-RAY DIFFRACTION (2.39 Å)
Cite:	De novo discovery of a non-covalent cell-penetrating bicyclic peptide inhibitor targeting SARS-CoV-2 main protease To Be Published

9J8U

Crystal structure of SARS-CoV-2 main protease in complex with Mp-4D7
Descriptor:	3C-like proteinase nsp5, DTY-VAL-THR-PHE-HIS-ALO-2TL-2TL-PRO-PHE-LEU-DPR-PRO-CCJ-GLY-NH2
Authors:	Shi, Y.S, Yang, J.Y, Wang, M.W.
Deposit date:	2024-08-21
Release date:	2025-07-02
Method:	X-RAY DIFFRACTION (2.71 Å)
Cite:	De novo discovery of a non-covalent cell-penetrating bicyclic pep-tide inhibitor targeting SARS-CoV-2 main protease To Be Published

9P6P

Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
Descriptor:	2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:	Minasov, G, Shuvalova, L, Maltseva, N, Kim, Y, Kiryukhina, O, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:	2025-06-19
Release date:	2025-07-02
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH). To Be Published

9CJP

X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir
Descriptor:	(1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ...
Authors:	Esler, M.A, Shi, K, Harris, R.S, Aihara, H.
Deposit date:	2024-07-07
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (1.71 Å)
Cite:	X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir To Be Published

9CJQ

X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Ensitrelvir
Descriptor:	1,2-ETHANEDIOL, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, main protease
Authors:	Esler, M.A, Shi, K, Harris, R.S, Aihara, H.
Deposit date:	2024-07-07
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (2.24 Å)
Cite:	X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Ensitrelvir To Be Published

9CJR

X-ray crystal structure of SARS-CoV-2 main protease double mutants in complex with Ensitrelvir
Descriptor:	3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, CHLORIDE ION, ...
Authors:	Esler, M.A, Shi, K, Harris, R.S, Aihara, H.
Deposit date:	2024-07-07
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	X-ray crystal structure of SARS-CoV-2 main protease double mutants in complex with Ensitrelvir To Be Published

9CJS

X-ray crystal structure of SARS-CoV-2 main protease triple mutants in complex with Bofutrelvir
Descriptor:	3C-like proteinase nsp5, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide
Authors:	Esler, M.A, Shi, K, Harris, R.S, Aihara, H.
Deposit date:	2024-07-07
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	X-ray crystal structure of SARS-CoV-2 main protease triple mutants in complex with Bofutrelvir To Be Published

9E9Q

SARS-CoV-2 SL5 crystal structure native
Descriptor:	MAGNESIUM ION, RNA (101-MER)
Authors:	Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:	2024-11-08
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (3.33 Å)
Cite:	Crystallographic and cryoEM analyses reveal SARS-CoV-2 SL5 is a mobile T-shaped four-way junction with deep pockets. Rna, 31, 2025

9MPW

SARS-CoV2 Spike S2 Subunit in complex with M15 Antibody Fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab M15 Heavy Chain, ...
Authors:	Sapse, I.A, Bajic, G.
Deposit date:	2024-12-31
Release date:	2025-07-09
Method:	ELECTRON MICROSCOPY (3.37 Å)
Cite:	SARS-CoV2 Spike S2 Subunit in complex with M15 Antibody Fragment To Be Published

9RCZ

Structure of the N-terminal domain of non-structural protein 1 (Nsp1) from SARS-CoV-2
Descriptor:	ORF1a polyprotein
Authors:	Lennartz, F, Weiss, M.S.
Deposit date:	2025-05-30
Release date:	2025-07-09
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystallographic fragment screening against SARS-CoV-2 Nsp1 using the F2X-Entry Screen and a newly developed fragment library. To Be Published

<76 77 78 79 80 81 82 83 84 85 86 87 88 89 9091

Total results:	2266
Displayed results:	16
Sorted by:	Release date (from oldest)