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신종 코로나바이러스 특집 콘텐츠

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코로나 바이러스
코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스(Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2)를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.


Created: 2020-09-03 (last edited: more than 1 year ago)2022-09-02
8QH0
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BU of 8qh0 by Molmil
Crystal structure of the SARS-CoV-2 RBD with the antibody Cv2.3194
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 Heavy chain, GLYCEROL, ...
Authors:Fernandez, I, Rey, F.A.
Deposit date:2023-09-06
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:A broadly neutralizing antibody against SARS-CoV-2 Omicron variants
To Be Published
8QH1
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BU of 8qh1 by Molmil
Crystal structure of the SARS-CoV-2 RBD from the Omicron BA4 variant with the antibody Cv2.3194
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cv2.3194 heavy chain, IGK@ protein, ...
Authors:Fernandez, I, Rey, F.A.
Deposit date:2023-09-06
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Pan-neutralizing antibody isolated from a COVID patient
To Be Published
8UKD
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BU of 8ukd by Molmil
SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-XBB.1.5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, Q.E, Acharya, P.
Deposit date:2023-10-12
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-XBB.1.5)
To Be Published
8XBF
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BU of 8xbf by Molmil
Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with antibody O5C2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, O5C2, heavy chain, ...
Authors:Hsu, H.F, Wu, M.H, Chang, Y.C, Hsu, S.T.D.
Deposit date:2023-12-06
Release date:2024-06-19
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody.
JCI Insight, 9, 2024
8XXW
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BU of 8xxw by Molmil
Fab M2-7 complexed with SARS-Cov2 RBD and human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, M2-7-Heavy chain, M2-7-Light chain, ...
Authors:Liu, C, Xie, Y.
Deposit date:2024-01-19
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses.
Cell Rep, 43, 2024
8YB5
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BU of 8yb5 by Molmil
SARS-CoV-2 DMV nsp3-4 pore complex (consensus-pore, C6 symmetry)
Descriptor: Non-structural protein 4, Papain-like protease nsp3
Authors:Huang, Y.X, Zhong, L.J, Zhang, W.X, Ni, T.
Deposit date:2024-02-11
Release date:2024-06-19
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Molecular architecture of coronavirus double-membrane vesicle pore complex.
Nature, 633, 2024
9EOW
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BU of 9eow by Molmil
The 5-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH
Descriptor: RNA (29-MER)
Authors:Wacker, A, Schwalbe, H.
Deposit date:2024-03-15
Release date:2024-06-19
Last modified:2024-07-31
Method:SOLUTION NMR
Cite:The 5'-terminal stem-loop RNA element of SARS-CoV-2 features highly dynamic structural elements that are sensitive to differences in cellular pH.
Nucleic Acids Res., 52, 2024
8T7Y
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BU of 8t7y by Molmil
Structure of SARS CoV-2 main protease in complex with Chymostatin.
Descriptor: 3C-like proteinase nsp5, Chymostatin A (bound form)
Authors:Terzyan, S, Yarla, N, Rao, C.V, Mooers, B.
Deposit date:2023-06-21
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of SARS CoV-2 main protease in complex with Chymostatin.
to be published
8WHZ
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BU of 8whz by Molmil
BA.2.86 RBD in complex with hACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:Yue, C, Liu, P.
Deposit date:2023-09-23
Release date:2024-06-26
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8X4Z
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BU of 8x4z by Molmil
BA.2.86 Spike Trimer with ins483V mutation (3 RBD down)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yue, C, Liu, P.
Deposit date:2023-11-16
Release date:2024-06-26
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8OYT
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BU of 8oyt by Molmil
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ...
Authors:Weckener, M, Naismith, J.H, Owens, R.J.
Deposit date:2023-05-05
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8WHU
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BU of 8whu by Molmil
Spike Trimer of BA.2.86 in complex with two hACE2s
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ...
Authors:Yue, C, Liu, P.
Deposit date:2023-09-23
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8WHV
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BU of 8whv by Molmil
Spike Trimer of BA.2.86 with three RBDs down
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Yue, C, Liu, P.
Deposit date:2023-09-23
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8WP8
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BU of 8wp8 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F.
Deposit date:2023-10-09
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 RBD in complex with human ACE2
To Be Published
8X5Q
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BU of 8x5q by Molmil
SARS-CoV-2 BA.2.75 Spike with K356T mutation (3 RBD down)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yue, C, Liu, P.
Deposit date:2023-11-17
Release date:2024-07-03
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
8XLV
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BU of 8xlv by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-26
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XM5
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BU of 8xm5 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-27
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XMG
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BU of 8xmg by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-27
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XMT
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BU of 8xmt by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN2
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BU of 8xn2 by Molmil
SARS-CoV-2 Omicron EG.5.1 RBD in complex with human ACE2 (local refined from the spike protein)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN3
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BU of 8xn3 by Molmil
SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-28
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XN5
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BU of 8xn5 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-29
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XNF
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BU of 8xnf by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-29
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XNK
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BU of 8xnk by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F.
Deposit date:2023-12-30
Release date:2024-07-03
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
8XUS
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BU of 8xus by Molmil
JN.1 Spike Trimer in complex with heparan sulfate
Descriptor: 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Yue, C, Liu, P.
Deposit date:2024-01-14
Release date:2024-07-03
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024

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