9J8T
 
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9J8U
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9P6P
 | | Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH). | | 分子名称: | 2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Minasov, G, Shuvalova, L, Maltseva, N, Kim, Y, Kiryukhina, O, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2025-06-19 | | 公開日 | 2025-07-02 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of the SARS-CoV-2 2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and S-Adenosyl-L-homocysteine (SAH).
To Be Published
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9CJO
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9CJP
 | | X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... | | 著者 | Esler, M.A, Shi, K, Harris, R.S, Aihara, H. | | 登録日 | 2024-07-07 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Nirmatrelvir
To Be Published
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9CJQ
 | | X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Ensitrelvir | | 分子名称: | 1,2-ETHANEDIOL, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, main protease | | 著者 | Esler, M.A, Shi, K, Harris, R.S, Aihara, H. | | 登録日 | 2024-07-07 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | X-ray crystal structure of SARS-CoV-2 main protease quadruple mutants in complex with Ensitrelvir
To Be Published
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9CJR
 | | X-ray crystal structure of SARS-CoV-2 main protease double mutants in complex with Ensitrelvir | | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, CHLORIDE ION, ... | | 著者 | Esler, M.A, Shi, K, Harris, R.S, Aihara, H. | | 登録日 | 2024-07-07 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | X-ray crystal structure of SARS-CoV-2 main protease double mutants in complex with Ensitrelvir
To Be Published
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9CJS
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9CJT
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9CJU
 | | Structure of SARS-CoV-2 main protease in complex with Bofutrelvir in orthorhombic form | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural protein 7, ... | | 著者 | Esler, M.A, Shi, K, Harris, R.S, Aihara, H. | | 登録日 | 2024-07-07 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | To be published
To Be Published
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9CJV
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9E9Q
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9FWH
 | | Crystal Structure of SARS-CoV-2 NSP10-ExoN in complex with VT00019 | | 分子名称: | (4R)-4-phenyl-1,2-thiazolidine 1,1-dioxide, Guanine-N7 methyltransferase nsp14, Non-structural protein 10, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-ExoN in complex with VT00019
To Be Published
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9FWI
 | | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00025 | | 分子名称: | (3-oxidanylazetidin-1-yl)-phenyl-methanone, DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.533 Å) | | 主引用文献 | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00025
To Be Published
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9FWJ
 | | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00079 | | 分子名称: | 2-methoxybenzamide, Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.424 Å) | | 主引用文献 | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00079
To Be Published
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9FWL
 | | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00025 | | 分子名称: | 3-phenylthiophene-2-carboxamide, DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00025
To Be Published
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9FWM
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00180 | | 分子名称: | 1H-indole-3-carboxamide, DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.574 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00180
To Be Published
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9FWN
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00219 | | 分子名称: | 1-methyl-1-(phenylmethyl)urea, DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.866 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00219
To Be Published
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9FWO
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00216 | | 分子名称: | 1-methylpyrrole-2-carboxamide, Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.179 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00216
To Be Published
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9FWP
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00198 | | 分子名称: | Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, N-methylbenzamide, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00198
To Be Published
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9FWQ
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00218 | | 分子名称: | 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine, Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.322 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00218
To Be Published
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9FWR
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00249 | | 分子名称: | (4R)-4-phenyl-1,3-oxazolidin-2-one, Guanine-N7 methyltransferase nsp14, MAGNESIUM ION, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00249
To Be Published
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9FWS
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00258 | | 分子名称: | 7-METHOXY-1H-INDAZOLE, DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.433 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00258
To Be Published
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9FWT
 | | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00259 | | 分子名称: | DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, Non-structural protein 10, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.639 Å) | | 主引用文献 | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00259
To Be Published
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9FWU
 | | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00421 | | 分子名称: | DIMETHYL SULFOXIDE, Guanine-N7 methyltransferase nsp14, N,N-dimethyl-3-oxidanyl-benzamide, ... | | 著者 | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | 登録日 | 2024-06-30 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (1.425 Å) | | 主引用文献 | Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00421
To Be Published
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