9GRQ
 
 | SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline | 分子名称: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Kremling, V, Sprenger, J, Oberthuer, D, Kiene, A. | 登録日 | 2024-09-12 | 公開日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders To Be Published
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8WKE
 
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8WSH
 
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8WSJ
 
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8WSK
 
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9CSY
 
 | SARS-CoV-2 papain-like protease (PLpro) bound to PF-07957472 | 分子名称: | 2-methyl-5-(4-methylpiperazin-1-yl)-N-{1-[(2P)-2-(1-methyl-1H-pyrazol-4-yl)quinolin-4-yl]cyclopropyl}benzamide, Papain-like protease, ZINC ION, ... | 著者 | Mashalidis, E.H, Chang, J.S, Wu, H, Garnsey, M. | 登録日 | 2024-07-24 | 公開日 | 2024-10-02 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model. Sci Adv, 10, 2024
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9GTF
 
 | SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 57256190 | 分子名称: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Kremling, V, Sprenger, J, Oberthuer, D, Kiene, A. | 登録日 | 2024-09-17 | 公開日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders To Be Published
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9GUE
 
 | SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 57256189 | 分子名称: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Kremling, V, Sprenger, J, Oberthuer, D, Kiene, A. | 登録日 | 2024-09-19 | 公開日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders To Be Published
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9GUF
 
 | SARS-CoV-2 methyltransferase nsp10-16 in complex with SAM and theophylline derivative LAS 54571106 | 分子名称: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Kremling, V, Sprenger, J, Oberthuer, D, Kiene, A. | 登録日 | 2024-09-19 | 公開日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 methyltransferase nsp10-16 with Cap0-site binders To Be Published
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8K18
 
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8K19
 
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8U4Y
 
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8WXL
 
 | Structure of the SARS-CoV-2 BA.2.86 spike glycoprotein (closed state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2023-10-30 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XUX
 
 | Structure of the SARS-CoV-2 BA.2.86 spike protein (1-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2025-06-18 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XUY
 
 | Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XUZ
 
 | Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (2-up and 1-down state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XV0
 
 | Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XV1
 
 | Structure of SARS-CoV-2 BA.2.86 spike RBD in complex with ACE2 (down state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-14 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8XVM
 
 | Structure of SARS-CoV-2 BA.2.86 spike glycoprotein in complex with ACE2 (3-up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-01-15 | 公開日 | 2024-10-09 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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9IU1
 
 | Structure of SARS-CoV-2 JN.1 spike RBD in complex with ACE2 (up state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Yajima, H, Anraku, Y, Kita, S, Kimura, K, Maenaka, K, Hashiguchi, T. | 登録日 | 2024-07-20 | 公開日 | 2024-10-09 | 最終更新日 | 2024-11-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1. Nat Commun, 15, 2024
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8WPW
 
 | Cryo-EM structure of SARS-CoV-2 XBB.1.5 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CB6 fab mutant heavy chain, CB6 fab mutant light chain, ... | 著者 | Su, C, Qi, J.X, Gao, G.F. | 登録日 | 2023-10-10 | 公開日 | 2024-10-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | An improved design method enables the ineffective etesevimab broadly and efficiently against SARS-CoV-2 Omicron subvariants To Be Published
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8WPY
 
 | Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies | 分子名称: | CB6 fab mutant heavy chain, CB6 fab mutant light chain, S304 fab heavy chain, ... | 著者 | Su, C, Qi, J.X, Gao, G.F. | 登録日 | 2023-10-10 | 公開日 | 2024-10-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | An improved design method enables the ineffective etesevimab broadly and efficiently against SARS-CoV-2 Omicron subvariants To Be Published
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9ATM
 
 | SARS-CoV-2 EG.5 RBD bound to the VIR-7229 and the S2H97 Fab fragments | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rietz, T, Park, Y.J, Errico, J, Czudnochowski, N, Nix, J.C, Corti, D, Snell, G, Marco, A.D, Pinto, D, Cameroni, E, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 登録日 | 2024-02-27 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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9AU1
 
 | SARS-CoV-2 XBB.1.5 RBD bound to the VIR-7229 and the S309 Fab fragments | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Rietz, T, Park, Y.J, Errico, J, Czudnochowski, N, Nix, J.C, Corti, D, Snell, G, Marco, A.D, Pinto, D, Cameroni, E, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D, Structural Genomics Consortium (SGC) | 登録日 | 2024-02-27 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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9AU2
 
 | VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Tortorici, M.A, Park, Y.J, Veelser, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2024-02-28 | 公開日 | 2024-10-16 | 最終更新日 | 2024-12-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification. Cell, 187, 2024
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