Entry Database : PDB / ID : 6uoe Structure visualization Downloads & linksTitle 3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide Components3-25 Fab heavy chain 3-25 Fab light chain Envelope glycoprotein B DetailsKeywords IMMUNE SYSTEM/VIRAL PROTEIN / fragment antigen-binding / viral peptide / HCMV gB / IMMUNE SYSTEM-VIRAL PROTEIN complexFunction / homology Function and homology informationFunction Domain/homology Component
immunoglobulin complex / host cell Golgi membrane / immunoglobulin complex, circulating / immunoglobulin receptor binding / host cell endosome membrane / complement activation, classical pathway / antigen binding / antibacterial humoral response / adaptive immune response / blood microparticle ... immunoglobulin complex / host cell Golgi membrane / immunoglobulin complex, circulating / immunoglobulin receptor binding / host cell endosome membrane / complement activation, classical pathway / antigen binding / antibacterial humoral response / adaptive immune response / blood microparticle / symbiont entry into host cell / viral envelope / virion attachment to host cell / host cell plasma membrane / virion membrane / extracellular space / extracellular exosome / membrane / plasma membrane Similarity search - Function Herpesvirus Glycoprotein B, antigenic domain, N-terminal / Glycoprotein B N-terminal antigenic domain of HCMV / Herpesvirus Glycoprotein B ectodomain / Herpesvirus Glycoprotein B / Herpesvirus Glycoprotein B, PH-like domain 1 / Herpesvirus Glycoprotein B, PH-like domain 2 / Herpesvirus Glycoprotein B / Herpesvirus Glycoprotein B PH-like domain / Herpesvirus Glycoprotein B, PH-like domain 2 superfamily / Immunoglobulin V-Type ... Herpesvirus Glycoprotein B, antigenic domain, N-terminal / Glycoprotein B N-terminal antigenic domain of HCMV / Herpesvirus Glycoprotein B ectodomain / Herpesvirus Glycoprotein B / Herpesvirus Glycoprotein B, PH-like domain 1 / Herpesvirus Glycoprotein B, PH-like domain 2 / Herpesvirus Glycoprotein B / Herpesvirus Glycoprotein B PH-like domain / Herpesvirus Glycoprotein B, PH-like domain 2 superfamily / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin subtype / Immunoglobulin / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold Similarity search - Domain/homology DI(HYDROXYETHYL)ETHER / Envelope glycoprotein B / Immunoglobulin gamma-1 heavy chain / Immunoglobulin kappa light chain Similarity search - ComponentBiological species Homo sapiens (human) Human betaherpesvirus 5Method X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution : 1.8 Å DetailsAuthors Wrapp, D. / McLellan, J.S. CitationJournal : Plos Pathog. / Year : 2020Title : Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.Authors : Ye, X. / Su, H. / Wrapp, D. / Freed, D.C. / Li, F. / Yuan, Z. / Tang, A. / Li, L. / Ku, Z. / Xiong, W. / Jaijyan, D. / Zhu, H. / Wang, D. / McLellan, J.S. / Zhang, N. / Fu, T.M. / An, Z. History Deposition Oct 14, 2019 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jul 29, 2020 Provider : repository / Type : Initial releaseRevision 1.1 Feb 10, 2021 Group : Database references / Category : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year Revision 1.2 Oct 11, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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