PDB-4u6f: Crystal structure of T-2 toxin bound to the yeast 80S ribosome

Basic information

• Entry: Database: PDB / ID: 4u6f
• Title: Crystal structure of T-2 toxin bound to the yeast 80S ribosome

Components

• (40S ribosomal protein ...) x 32
• (60S ribosomal protein ...) x 40
• (unknown protein chain ...) x 3
• 18S ribosomal RNA
• 25S ribosomal RNA
• 5.8S ribosomal RNA
• 5S ribosomal RNA
• 60S acidic ribosomal protein P0
• Guanine nucleotide-binding protein subunit beta-like protein
• Suppressor protein STM1
• Ubiquitin-40S ribosomal protein S31
• Ubiquitin-60S ribosomal protein L40

• Keywords: RIBOSOME / translation / 40S / 60S / 80S / eukaryote / RNA-protein complex / inhibitor / antibiotic

Function / homology

Function:

triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / Negative regulators of DDX58/IFIH1 signaling / negative regulation of glucose mediated signaling pathway / positive regulation of translational fidelity / RMTs methylate histone arginines / Protein methylation / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / pre-mRNA 5'-splice site binding / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / preribosome, small subunit precursor / Ribosomal scanning and start codon recognition / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / nonfunctional rRNA decay / response to cycloheximide / telomeric DNA binding / Major pathway of rRNA processing in the nucleolus and cytosol / mRNA destabilization / negative regulation of translational frameshifting / SRP-dependent cotranslational protein targeting to membrane / GTP hydrolysis and joining of the 60S ribosomal subunit / TOR signaling / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / negative regulation of mRNA splicing, via spliceosome / Formation of a pool of free 40S subunits / preribosome, large subunit precursor / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / L13a-mediated translational silencing of Ceruloplasmin expression / translational elongation / regulation of amino acid metabolic process / ribosomal large subunit export from nucleus / positive regulation of protein kinase activity / G-protein alpha-subunit binding / 90S preribosome / Ub-specific processing proteases / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein-RNA complex assembly / regulation of translational fidelity / ribosomal subunit export from nucleus / maturation of LSU-rRNA / translational termination / ribosomal small subunit export from nucleus / translation regulator activity / translation repressor activity / rescue of stalled ribosome / DNA-(apurinic or apyrimidinic site) endonuclease activity / telomere maintenance / cellular response to amino acid starvation / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit biogenesis / ribosome assembly / protein kinase C binding / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / translational initiation / macroautophagy / maintenance of translational fidelity / modification-dependent protein catabolic process / protein tag activity / rRNA processing / cytoplasmic stress granule / ribosome biogenesis / ribosome binding / ribosomal small subunit assembly / ribosomal small subunit biogenesis / small ribosomal subunit / small ribosomal subunit rRNA binding / 5S rRNA binding / ribosomal large subunit assembly / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / cytosolic large ribosomal subunit / cytoplasmic translation / negative regulation of translation / rRNA binding / protein ubiquitination / ribosome / structural constituent of ribosome / G protein-coupled receptor signaling pathway / translation / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / negative regulation of apoptotic process / nucleolus / perinuclear region of cytoplasm / mitochondrion / DNA binding

Domain/homology:

Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / : / : / Ribosomal protein S26e signature. / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / : / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / S27a-like superfamily / Ribosomal L38e protein family / 40S Ribosomal protein S10 / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L10e, conserved site / Ribosomal protein L44e signature. / Ribosomal protein L10e signature. / Ribosomal protein L10e / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L19, eukaryotic / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein S10, eukaryotic/archaeal / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein L19/L19e conserved site / : / : / Ribosomal protein L19e signature. / Ribosomal protein S7e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Ribosomal protein L44e / Ribosomal protein S17e, conserved site / Ribosomal protein L44 / Ribosomal protein S17e signature. / : / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein L6e signature. / Ribosomal protein S27a / Ribosomal protein S30 / Ribosomal protein S30 / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein L30e signature 1. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein S3Ae, conserved site / Ribosomal protein S3Ae signature. / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal L40e family / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal_L40e / Ribosomal protein L40e / 40S ribosomal protein S4, C-terminal domain / Ribosomal protein L40e superfamily / 40S ribosomal protein S4 C-terminus / Ribosomal protein S4e, N-terminal, conserved site / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein S4e signature. / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein S3, eukaryotic/archaeal

Component:

osmium (III) hexammine / Chem-ZBA / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein uS11A / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Large ribosomal subunit protein eL18A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A

• Biological species: Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.1 Å
• Authors: Garreau de Loubresse, N. / Prokhorova, I. / Yusupova, G. / Yusupov, M.
• Citation: Journal: Nature / Year: 2014; Title: Structural basis for the inhibition of the eukaryotic ribosome.; Authors: Garreau de Loubresse, N. / Prokhorova, I. / Holtkamp, W. / Rodnina, M.V. / Yusupova, G. / Yusupov, M.

History

Deposition	Jul 28, 2014	Deposition site: RCSB / Processing site: PDBE
Revision 1.0	Oct 22, 2014	Provider: repository / Type: Initial release
Supersession	Dec 10, 2014	ID: 4uju, 4ujv, 4ujw, 4ujx, 4ujy
Revision 1.1	Dec 10, 2014	Group: Other
Revision 1.2	Dec 17, 2014	Group: Other
Revision 1.3	Jan 21, 2015	Group: Derived calculations
Revision 1.4	Jan 20, 2016	Group: Structure summary
Revision 1.5	Dec 20, 2023	Group: Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_conn_type Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id
Revision 1.6	Nov 20, 2024	Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature

Assembly

Deposited unit

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

m2: unknown protein chain m2

p1: unknown protein chain p1

p2: unknown protein chain p2

hetero molecules

Summary:

• 6.63 MDa, 162 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	6,631,365	2720
Polymers	6,271,265	162
Non-polymers	360,100	2558
Water	0	0

1

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

hetero molecules

Summary:

• defined by author
• 3.28 MDa, 79 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,284,889	1323
Polymers	3,107,917	79
Non-polymers	176,972	1244
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

m2: unknown protein chain m2

p1: unknown protein chain p1

p2: unknown protein chain p2

hetero molecules

Summary:

• defined by author
• 3.35 MDa, 83 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,346,476	1397
Polymers	3,163,348	83
Non-polymers	183,128	1314
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	436.640, 287.690, 304.390
Angle α, β, γ (deg.)	90.000, 98.980, 90.000
Int Tables number	4
Space group name H-M	P1211

• Details: there are 2 biological units in the asymetric unit (segid *A and segid *B)

Components

RNA chain , 4 types, 8 molecules 2 6 1 5 3 7 4 8

#1: RNA chain

2 6 18S ribosomal RNA / RNA (1781-MER)

Details:

Mass: 579761.938 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 1262303

#36: RNA chain

1 5 25S ribosomal RNA / RNA (3149-MER)

Details:

Mass: 1097493.875 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#37: RNA chain

3 7 5S ribosomal RNA / RNA (121-MER)

Details:

Mass: 38951.105 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#38: RNA chain

4 8 5.8S ribosomal RNA / RNA (158-MER)

Details:

Mass: 50682.922 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 618731124

40S ribosomal protein ... , 32 types, 62 molecules S0 s0 S1 s1 S2 s2 S3 s3 S4 s4 S5 s5 S6 s6 S7 s7 S8 s8 S9 s9 C0 c0 C1 c1 C2 c2 C3 c3 C4 c4 ...

#2: Protein

S0 s0 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A

Details:

Mass: 27920.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P32905

#3: Protein

S1 s1 40S ribosomal protein S1-A / RP10A

Details:

Mass: 28667.275 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P33442

#4: Protein

S2 s2 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / YS5

Details:

Mass: 27359.629 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P25443

#5: Protein

S3 s3 40S ribosomal protein S3 / RP13 / YS3

Details:

Mass: 26411.596 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05750

#6: Protein

S4 s4 40S ribosomal protein S4-A / RP5 / S7 / YS6

Details:

Mass: 29338.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX35

#7: Protein

S5 s5 40S ribosomal protein S5 / RP14 / S2 / YS8

Details:

Mass: 24941.402 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26783

#8: Protein

S6 s6 40S ribosomal protein S6-A / RP9 / S10 / YS4

Details:

Mass: 27054.486 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX37

#9: Protein

S7 s7 40S ribosomal protein S7-A / RP30 / RP40

Details:

Mass: 21527.014 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26786

#10: Protein

S8 s8 40S ribosomal protein S8-A / RP19 / S14 / YS9

Details:

Mass: 22537.803 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX39

#11: Protein

S9 s9 40S ribosomal protein S9-A / RP21 / S13 / YP28 / YS11

Details:

Mass: 22356.695 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: O13516

#12: Protein

C0 c0 40S ribosomal protein S10-A

Details:

Mass: 12757.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q08745

#13: Protein

C1 c1 40S ribosomal protein S11-A / RP41 / S18 / YS12

Details:

Mass: 17668.766 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX47

#14: Protein

C2 c2 40S ribosomal protein S12

Details:

Mass: 15385.485 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P48589

#15: Protein

C3 c3 40S ribosomal protein S13 / S27a / YS15

Details:

Mass: 16928.748 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05756

#16: Protein

C4 c4 40S ribosomal protein S14-A / RP59A

Details:

Mass: 14431.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P06367

#17: Protein

C5 c5 40S ribosomal protein S15 / RIG protein / RP52 / S21 / YS21

Details:

Mass: 15830.597 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q01855

#18: Protein

C6 c6 40S ribosomal protein S16-A / RP61R

Details:

Mass: 15746.292 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX51

#19: Protein

C7 c7 40S ribosomal protein S17-A / RP51A

Details:

Mass: 15820.413 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02407

#20: Protein

C8 c8 40S ribosomal protein S18-A

Details:

Mass: 16940.443 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX55

#21: Protein

C9 c9 40S ribosomal protein S19-A / RP55A / S16a / YP45 / YS16A

Details:

Mass: 15810.930 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P07280

#22: Protein

D0 d0 40S ribosomal protein S20

Details:

Mass: 13797.850 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38701

#23: Protein

D1 d1 40S ribosomal protein S21-A / S26 / YS25

Details:

Mass: 9758.829 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0V8

#24: Protein

D2 d2 40S ribosomal protein S22-A / RP50 / S24 / YP58 / YS22

Details:

Mass: 14518.867 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0W1

#25: Protein

D3 d3 40S ribosomal protein S23-A / RP37 / S28 / YS14

Details:

Mass: 15942.699 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX29

#26: Protein

D4 d4 40S ribosomal protein S24-A / RP50

Details:

Mass: 15231.650 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX31

#27: Protein

D5 d5 40S ribosomal protein S25-A / RP45 / S31 / YS23

Details:

Mass: 11936.076 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E792

#28: Protein

D6 d6 40S ribosomal protein S26-B

Details:

Mass: 11022.989 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39939

#29: Protein

D7 d7 40S ribosomal protein S27-A / RP61 / YS20

Details:

Mass: 8762.195 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P35997

#30: Protein

D8 d8 40S ribosomal protein S28-A / S33 / YS27

Details:

Mass: 7474.652 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E7X9

#31: Protein

D9 d9 40S ribosomal protein S29-A / S36 / YS29

Details:

Mass: 6544.527 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41057

#32: Protein

E0 40S ribosomal protein S30-A

Details:

Mass: 6779.086 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

#80: Protein

e0 40S ribosomal protein S30-A

Details:

Mass: 7006.346 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

Protein , 5 types, 9 molecules E1 e1 SR sR SM sM Q0 q0 p0

#33: Protein

E1 e1 Ubiquitin-40S ribosomal protein S31

Details:

Mass: 8703.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05759

#34: Protein

SR sR Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1

Details:

Mass: 34710.023 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38011

#35: Protein

SM sM Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1

Details:

Mass: 30048.010 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39015

#76: Protein

Q0 q0 Ubiquitin-60S ribosomal protein L40

Details:

Mass: 6032.321 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CH08

#81: Protein

p0 60S acidic ribosomal protein P0 / A0 / L10E

Details:

Mass: 33617.930 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05317

60S ribosomal protein ... , 40 types, 80 molecules L2 l2 L3 l3 L4 l4 L5 l5 L6 l6 L7 l7 L8 l8 L9 l9 M0 m0 M1 m1 M3 m3 M4 m4 M5 m5 M6 m6 M7 m7 ...

#39: Protein

L2 l2 60S ribosomal protein L2-A / L5 / RP8 / YL6

Details:

Mass: 27332.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX45

#40: Protein

L3 l3 60S ribosomal protein L3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1

Details:

Mass: 43719.602 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14126

#41: Protein

L4 l4 60S ribosomal protein L4-A / L2 / RP2 / YL2

Details:

Mass: 39027.926 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P10664

#42: Protein

L5 l5 60S ribosomal protein L5 / L1 / L1a / Ribosomal 5S RNA-binding protein / YL3

Details:

Mass: 33633.633 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26321

#43: Protein

L6 l6 60S ribosomal protein L6-A / L17 / RP18 / YL16

Details:

Mass: 19869.369 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02326

#44: Protein

L7 l7 60S ribosomal protein L7-A / L6 / RP11 / YL8

Details:

Mass: 27555.084 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05737

#45: Protein

L8 l8 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Maintenance of killer protein 7 / RP6 / YL5

Details:

Mass: 28044.621 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P17076

#46: Protein

L9 l9 60S ribosomal protein L9-A / L8 / RP24 / YL11

Details:

Mass: 21605.061 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05738

#47: Protein

M0 m0 60S ribosomal protein L10 / L9 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein

Details:

Mass: 25279.271 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41805

#48: Protein

M1 m1 60S ribosomal protein L11-B / L16 / RP39 / YL22

Details:

Mass: 19654.520 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E757

#49: Protein

M3 m3 60S ribosomal protein L13-A

Details:

Mass: 22472.967 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q12690

#50: Protein

M4 m4 60S ribosomal protein L14-A

Details:

Mass: 15063.870 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P36105

#51: Protein

M5 m5 60S ribosomal protein L15-A / L13 / RP15R / YL10 / YP18

Details:

Mass: 24351.162 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05748

#52: Protein

M6 m6 60S ribosomal protein L16-A / L13a / L21 / RP22 / YL15

Details:

Mass: 22116.029 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26784

#53: Protein

M7 m7 60S ribosomal protein L17-A / L20A / YL17

Details:

Mass: 20458.322 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05740

#54: Protein

M8 m8 60S ribosomal protein L18-A / RP28

Details:

Mass: 20478.059 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX49

#55: Protein

M9 m9 60S ribosomal protein L19-A / L23 / RP15L / RP33 / YL14

Details:

Mass: 21631.121 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX82

#56: Protein

N0 n0 60S ribosomal protein L20-A / L18a

Details:

Mass: 20478.852 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX23

#57: Protein

N1 n1 60S ribosomal protein L21-A

Details:

Mass: 18148.066 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02753

#58: Protein

N2 n2 60S ribosomal protein L22-A / L1c / RP4 / YL31

Details:

Mass: 13580.163 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05749

#59: Protein

N3 n3 60S ribosomal protein L23-A / L17a / YL32

Details:

Mass: 14362.755 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX41

#60: Protein

N4 n4 60S ribosomal protein L24-A / L30 / RP29 / YL21

Details:

Mass: 17661.717 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04449

#61: Protein

N5 n5 60S ribosomal protein L25 / RP16L / YL25 / YP42'

Details:

Mass: 15656.417 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04456

#62: Protein

N6 n6 60S ribosomal protein L26-A / L33 / YL33

Details:

Mass: 14134.588 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05743

#63: Protein

N7 n7 60S ribosomal protein L27-A

Details:

Mass: 15437.166 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H6

#64: Protein

N8 n8 60S ribosomal protein L28 / L27a / L29 / RP44 / RP62 / YL24

Details:

Mass: 16630.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02406

#65: Protein

N9 n9 60S ribosomal protein L29 / YL43

Details:

Mass: 6560.688 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05747

#66: Protein

O0 o0 60S ribosomal protein L30 / L32 / RP73 / YL38

Details:

Mass: 11299.168 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14120

#67: Protein

O1 o1 60S ribosomal protein L31-A / L34 / YL28

Details:

Mass: 12848.962 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H8

#68: Protein

O2 o2 60S ribosomal protein L32

Details:

Mass: 14678.246 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38061

#69: Protein

O3 o3 60S ribosomal protein L33-A / L37 / RP47 / YL37

Details:

Mass: 12045.935 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05744

#70: Protein

O4 o4 60S ribosomal protein L34-A

Details:

Mass: 13542.001 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P87262

#71: Protein

O5 o5 60S ribosomal protein L35-A

Details:

Mass: 13811.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX84

#72: Protein

O6 o6 60S ribosomal protein L36-A / L39 / YL39

Details:

Mass: 11020.063 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05745

#73: Protein

O7 o7 60S ribosomal protein L37-A / L43 / YL35 / YP55

Details:

Mass: 9746.199 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49166

#74: Protein

O8 o8 60S ribosomal protein L38

Details:

Mass: 8714.363 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49167

#75: Protein/peptide

O9 o9 60S ribosomal protein L39 / L46 / YL40

Details:

Mass: 6227.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04650

#77: Protein/peptide

Q1 q1 60S ribosomal protein L41-A

Details:

Mass: 3354.243 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#78: Protein

Q2 q2 60S ribosomal protein L42-A / L41 / YL27 / YP44

Details:

Mass: 12115.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX27

#79: Protein

Q3 q3 60S ribosomal protein L43-A / L37a / YL35

Details:

Mass: 9981.756 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX25

Unknown protein chain ... , 3 types, 3 molecules m2 p1 p2

#82: Protein

m2 unknown protein chain m2

Details:

Mass: 13634.798 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#83: Protein/peptide

p1 unknown protein chain p1

Details:

Mass: 4017.944 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#84: Protein/peptide

p2 unknown protein chain p2

Details:

Mass: 3932.839 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

Non-polymers , 4 types, 2558 molecules

#85: Chemical

2-1901 2-1902 2-1903 2-1904 2-1905 2-1906 2-1907 2-1908 2-1909 2-1910 2-1911 2-1912 2-1913 2-1914 2-1915 2-1916 2-1917 2-1918 2-1919 2-1920 ...
ChemComp-MG / MAGNESIUM ION

Details:

Mass: 24.305 Da / Num. of mol.: 1409 / Source method: obtained synthetically / Formula: Mg

#86: Chemical

2-2026 2-2027 2-2028 2-2029 2-2030 2-2031 2-2032 2-2033 2-2034 2-2035 2-2036 2-2037 2-2038 2-2039 2-2040 2-2041 2-2042 2-2043 2-2044 2-2045 ...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide

Details:

Mass: 286.365 Da / Num. of mol.: 1131 / Source method: obtained synthetically / Formula: H₁₂N₆Os

#87: Chemical

D6-500 D7-101 D9-101 E1-501 O7-101 Q0-500 Q2-501 Q3-501 d6-101 d7-101 d9-101 e1-501 o7-501 q0-201 q2-501 q3-501
ChemComp-ZN / ZINC ION

Details:

Mass: 65.409 Da / Num. of mol.: 16 / Source method: obtained synthetically / Formula: Zn

#88: Chemical

1-4206 5-4256 ChemComp-ZBA / 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate

Details:

Mass: 464.505 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Formula: C₂₄H₃₂O₉

Details

• Has protein modification: Y

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 3.07 ų/Da / Density % sol: 59.87 %
• Crystal grow: Temperature: 277 K / Method: vapor diffusion, hanging drop / pH: 7.5 ; Details: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: SOLEIL / Beamline: PROXIMA 1 / Wavelength: 1 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Jul 1, 2013
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 1 Å / Relative weight: 1
• Reflection: Resolution: 2.9→300.66 Å / Num. obs: 1614049 / % possible obs: 98.8 % / Observed criterion σ(I): -3 / Redundancy: 5.69 % / B_iso Wilson estimate: 71.82 Ų / R_merge F obs: 0.457 / R_merge(I) obs: 0.401 / R_rim(I) all: 0.436 / Χ²: 0.925 / Net I/σ(I): 4.19 / Num. measured all: 9178598

Reflection shell

Diffraction-ID: 1 / Rejects: _

Resolution (Å)	Highest resolution (Å)	Rmerge F obs	Rmerge(I) obs	Mean I/σ(I) obs	Num. measured obs	Num. possible	Num. unique obs	Rrim(I) all	% possible all
2.9-3		3.237	3.839	0.49	804886	157700	155367	4.259	98.5
3-3.1		2.174	2.663	0.76	744631	138084	137486	2.942	99.6
3.1-3.2		1.589	1.949	1.05	648724	121226	120642	2.154	99.5
3.2-3.3		1.265	1.548	1.33	559490	107007	106203	1.714	99.2
3.3-3.4		1.021	1.246	1.64	482990	94762	93921	1.382	99.1
3.4-3.6		0.747	0.955	2.18	847462	159586	157406	1.053	98.6
3.6-4		0.447	0.595	3.45	1248551	231347	229163	0.655	99.1
4-4.25		0.289	0.392	4.86	530834	103461	101894	0.434	98.5
4.25-4.5		0.219	0.316	5.87	432486	81804	80140	0.348	98
4.5-4.75		0.182	0.271	6.71	354614	65515	64616	0.298	98.6
4.75-5		0.157	0.237	7.42	283516	53066	52287	0.261	98.5
5-8		0.118	0.185	8.96	1253019	241716	236123	0.204	97.7
8-9		0.138	0.53	11.48	286684	23363	23329	0.553	99.9
9-10		0.11	0.428	13.05	196612	14933	14930	0.446	100
10-50		0.074	0.215	15.97	501722	40231	40200	0.225	99.9
50-200		0.031	0.074	32.18	2367	350	339	0.08	96.9
200-300		0.022	0.087	29.79	8	5	2	0.1	40
300-400		0.041	0.041	21.22	2	1	1	0.058	100
	400					1

Processing

Software

Name	Version	Classification
XDS		data reduction
PHENIX	(phenix.refine: dev_1702)	refinement
PDB_EXTRACT	3.14	data extraction
XSCALE		data scaling
XSCALE		data reduction

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 3U5B, 3U5C, 3U5D, 3U5E, 3U5F, 3U5G, 3U5H, 3U5I

3u5b
PDB Unreleased entry

3u5c
PDB Unreleased entry

3u5d
PDB Unreleased entry

3u5e
PDB Unreleased entry

3u5f
PDB Unreleased entry

3u5g
PDB Unreleased entry

3u5h
PDB Unreleased entry

3u5i
PDB Unreleased entry

Resolution: 3.1→300.66 Å / SU ML: 0.44 / Cross valid method: FREE R-VALUE / σ(F): 0 / Phase error: 24.67 / Stereochemistry target values: ML

	Rfactor	Num. reflection	% reflection
Rfree	0.2467	26417	2 %
Rwork	0.1978	1294469	-
obs	0.1988	1320886	98.7 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso max: 288.92 Ų / B_iso mean: 68.1262 Ų / B_iso min: 9.4 Ų

Refinement step

Cycle: final / Resolution: 3.1→300.66 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	179692	222781	10988	0	413461
Biso mean	-	-	129.01	-	-
Num. residues	-	-	-	-	33021

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.011	442182
X-RAY DIFFRACTION	f_angle_d	1.513	655755
X-RAY DIFFRACTION	f_chiral_restr	0.06	80075
X-RAY DIFFRACTION	f_plane_restr	0.007	42356
X-RAY DIFFRACTION	f_dihedral_angle_d	18.959	196436

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection all	% reflection obs (%)
3.1-3.1352	0.3565	884	0.3127	43326	44210	99
3.1352-3.1721	0.349	885	0.3027	43366	44251	99
3.1721-3.2108	0.3325	884	0.2894	43293	44177	99
3.2108-3.2515	0.3365	883	0.282	43265	44148	99
3.2515-3.2942	0.339	883	0.2824	43273	44156	99
3.2942-3.3394	0.3237	882	0.2662	43221	44103	99
3.3394-3.3871	0.2991	882	0.2516	43230	44112	99
3.3871-3.4376	0.2966	883	0.2511	43230	44113	99
3.4376-3.4914	0.3045	868	0.2455	42600	43468	98
3.4914-3.5486	0.2903	882	0.2323	43173	44055	99
3.5486-3.6098	0.2864	883	0.2297	43272	44155	99
3.6098-3.6755	0.271	885	0.2206	43381	44266	99
3.6755-3.7462	0.256	882	0.2031	43168	44050	99
3.7462-3.8226	0.2568	882	0.1964	43261	44143	99
3.8226-3.9058	0.2431	883	0.1891	43257	44140	99
3.9058-3.9966	0.2418	882	0.1835	43211	44093	99
3.9966-4.0966	0.2285	878	0.1753	43048	43926	99
4.0966-4.2073	0.2365	877	0.1744	42932	43809	98
4.2073-4.3312	0.2259	870	0.1735	42636	43506	98
4.3312-4.471	0.2233	877	0.1704	43007	43884	98
4.471-4.6308	0.2156	881	0.1628	43182	44063	99
4.6308-4.8162	0.2068	881	0.1587	43092	43973	99
4.8162-5.0354	0.2015	876	0.153	43022	43898	98
5.0354-5.3009	0.214	877	0.1605	43029	43906	98
5.3009-5.6331	0.2202	875	0.1637	42844	43719	98
5.6331-6.068	0.2058	868	0.1614	42529	43397	97
6.068-6.6787	0.211	874	0.1654	42836	43710	98
6.6787-7.6452	0.2227	876	0.1742	42846	43722	98
7.6452-9.6323	0.2401	891	0.1966	43658	44549	99
9.6323-302.0856	0.2461	903	0.2261	44281	45184	100

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.9043	-0.0455	-0.6523	0.0907	-0.0263	1.3241	0.0371	-0.0394	-0.3029	0.2005	-0.0636	0.1448	0.0897	-0.0494	0.0211	0.8076	-0.392	0.4954	1.1583	-0.2978	1.2351	-110.7203	-8.3003	110.2796
2	0.6698	-0.6349	0.2527	1.0714	-0.1202	0.3663	-0.1027	-0.3766	-0.4162	0.5544	0.0553	0.1486	0.276	-0.0057	0.073	1.4484	-0.1803	0.232	0.9291	0.3702	0.8513	-46.9191	-27.943	139.2478
3	0.9485	0.2726	-0.0653	0.6721	0.0994	0.8068	0.0459	-0.0709	0.1686	0.131	-0.0348	0.4483	0.0673	-0.4022	-0.0079	0.392	-0.1146	0.0577	0.9445	-0.267	0.9392	-101.1152	9.6287	77.0387
4	0.6687	0.3067	-0.1497	0.537	-0.1426	0.2688	-0.0325	0.2761	0.0525	-0.0279	0.0436	0.1877	-0.0574	-0.1492	0.0077	0.4656	-0.1423	-0.0074	1.1207	-0.2496	0.9229	-99.6062	-29.3142	46.05
5	0.628	-0.0027	-0.2697	0.7215	0.1195	0.8422	0.0392	0.0142	0.163	-0.0203	0.0199	0.5038	-0.0984	-0.2344	-0.0268	0.5576	0.2801	0.0357	0.8111	0.0116	0.9912	-79.9548	81.2001	71.4813
6	0.9561	-0.4917	0.371	0.3909	0.2184	1.6444	0.0285	-0.3428	-0.2355	0.133	-0.1253	-0.0096	0.175	-0.0442	0.0879	0.9598	-0.3432	0.1416	0.5834	0.0349	0.7405	-76.6091	-77.3244	90.955
7	0.4994	-0.128	-0.1619	0.6815	-0.1	0.6813	0.0108	0.2294	0.2935	-0.2703	-0.1905	-0.157	-0.217	-0.0748	0.1609	0.764	0.1971	0.0585	0.6058	0.2374	0.9839	-30.0784	98.209	49.0095
8	0.9685	0.0515	-0.2716	0.4861	-0.204	0.5831	0.0401	-0.2396	0.2762	0.3585	-0.1394	0.1251	-0.0571	-0.2097	0.0685	0.8753	-0.065	0.4102	1.1223	-0.4059	0.9283	-97.6938	47.9463	136.5463
9	0.5928	0.0421	0.0442	1.6214	0.3499	0.7181	0.1286	-0.1369	0.2976	0.1097	-0.0879	-0.0708	-0.2002	-0.042	-0.0462	0.5695	0.0823	0.1605	0.4569	-0.0839	0.7463	-31.5326	89.0561	95.1007
10	0.668	0.0043	0.0552	0.6927	0.2735	0.8656	0.0229	0.2002	-0.0551	-0.0838	0.0149	0.2816	-0.0617	-0.1288	-0.0726	0.4155	0.098	-0.13	1.1201	-0.0758	1.0105	-96.5576	41.5635	48.6494
11	0.3633	-0.0085	0.1131	1.5769	-0.361	2.1714	0.2438	0.3853	0.0928	-0.1953	0.0607	0.1153	-0.0453	-0.3389	-0.267	0.5534	-0.1172	0.0205	1.2702	-0.0799	0.8016	-86.5562	-33.2112	14.121
12	1.0889	0.8565	0.2183	1.6136	0.3194	0.5224	0.1257	-0.3722	0.0902	0.2888	-0.2463	0.1132	-0.0511	-0.0472	0.0897	0.6293	0.0514	0.2014	0.6237	-0.1066	0.5816	-52.3284	67.078	105.1643
13	2.338	-1.2345	-0.1993	1.6068	-0.8252	0.9294	-0.032	0.0115	0.1332	-0.1667	-0.0195	0.1072	-0.0983	-0.1034	0.0342	1.1931	0.0221	-0.1009	1.5491	0.068	1.0452	-79.3338	-25.8037	-17.9348
14	0.4807	-0.0648	-0.5742	0.4712	0.0055	0.7717	0.0781	-0.3359	0.0453	0.4423	-0.1708	0.2526	-0.133	-0.1455	0.0423	0.7599	-0.2127	0.2692	0.8592	-0.1438	0.528	-60.5935	30.005	131.9713
15	0.2085	0.0567	0.1208	0.6715	0.1372	0.0865	-0.1016	-0.2169	-0.4124	0.1715	-0.0735	0.0843	0.4475	-0.0089	0.1361	1.1644	-0.2107	0.2236	0.5242	0.168	1.1413	-44.7904	-39.7201	116.2263
16	0.7458	0.5225	-0.4492	2.2276	0.1927	1.5692	-0.1003	0.1542	-0.0676	-0.3461	-0.0552	-0.1205	0.1617	-0.0042	0.1277	0.3911	-0.1576	0.1258	0.8339	-0.2872	0.9241	-46.8933	-70.3125	21.991
17	0.8243	0.4535	-0.3938	1.0499	-0.5376	0.4932	-0.0757	0.0345	0.0569	0.2265	0.0023	0.073	0.2284	-0.1319	0.0714	0.8771	-0.4299	0.2515	0.8556	-0.3699	0.9684	-98.1921	-77.3345	73.5386
18	0.0131	-0.0571	-0.0703	0.4744	0.7718	1.302	0.1324	0.0076	-0.0988	0.1486	-0.1169	0.1001	0.0074	-0.0859	0.0071	0.689	-0.3952	0.2391	0.8853	-0.3564	0.9765	-112.0558	-30.3605	98.4637
19	0.1983	0.1692	-0.1866	0.9727	-0.2303	0.3887	-0.1308	0.0654	-0.3066	0.1642	0.1666	-0.0355	0.364	0.0032	-0.0039	0.6626	-0.1956	0.1043	0.8207	-0.207	1.2493	-49.4139	-90.4588	49.3793
20	0.6206	0.3831	0.2241	0.9644	0.1252	0.15	-0.1716	0.1013	-0.2467	0.1076	-0.117	-0.0555	0.2054	-0.2374	0.191	0.904	-0.4167	0.2984	0.8024	-0.3969	1.2487	-82.935	-95.3644	51.9933
21	3.9247	1.5594	1.3042	1.2633	0.481	0.7893	0.0044	0.2525	0.2109	-0.1099	-0.1446	0.3652	-0.0387	-0.3063	0.1155	0.5084	-0.2341	0.0246	1.083	-0.3462	0.9675	-107.5071	-55.844	43.3342
22	0.9414	-0.2551	0.2771	0.5373	-0.0545	1.0572	0.0921	0.1953	0.1075	0.1659	0.0284	0.2284	0.0884	-0.3321	-0.1072	0.5971	-0.1459	0.3474	1.3306	-0.3418	1.3922	-111.0288	11.9887	101.6587
23	0.7976	0.0004	0.0353	0.482	0.3286	0.4822	0.1866	0.1091	0.2912	0.2689	-0.1015	0.5585	-0.0341	-0.4296	-0.0606	0.4679	-0.0277	0.2996	1.0001	-0.1496	0.9544	-90.0573	33.2037	101.9239
24	0.272	0.0023	-0.0128	0.7466	0.4971	0.6828	-0.0517	0.1603	0.0254	-0.0831	0.0239	0.1882	0.0021	-0.0237	-0.0355	0.4008	-0.0354	0.0801	0.6545	-0.1257	0.5838	-54.4628	21.3862	56.5561
25	1.1997	-0.064	0.3548	1.0074	-0.0366	0.6627	-0.1556	0.3311	0.1768	-0.3929	0.0491	0.3422	-0.3084	-0.5275	0.0908	0.7527	0.3003	-0.1646	1.0148	0.0618	0.8057	-74.0697	76.9017	33.9139
26	1.4916	-1.0771	-0.2874	1.4302	0.3531	1.1756	-0.1233	-0.2925	-0.134	0.1431	-0.1239	-0.2562	0.0783	0.1914	0.1835	1.3661	-0.2817	0.1572	0.6977	0.1322	1.256	-63.8226	-102.2718	81.5006
27	1.0468	-0.2589	0.1266	0.7608	0.0966	0.685	-0.0403	-0.1786	-0.3153	0.1918	0.1194	0.3999	0.5204	-0.4097	-0.051	0.9458	-0.2875	0.1669	0.7774	0.0413	1.2052	-61.1405	-23.0647	109.7595
28	1.7741	-0.0834	0.1518	1.186	0.0004	0.0127	0.0752	-0.4067	0.0646	0.4843	-0.0935	0.0287	-0.0678	-0.0557	0.0326	0.902	-0.2053	0.4518	1.0755	0.0148	0.8669	-80.7679	17.2441	141.306
29	1.614	-0.6654	0.3313	2.1216	-0.2725	2.7246	0.0865	-0.4564	0.0496	0.4878	-0.0805	-0.3069	-0.3165	0.2451	-0.0079	1.4273	-0.4366	0.1534	1.0977	-0.1858	0.8251	-76.1504	-57.1709	107.411
30	1.8965	-0.1037	-0.8798	1.1839	0.1513	0.8701	-0.0847	0.2532	-0.0625	-0.1024	-0.0378	0.3543	0.0222	-0.2012	0.1069	0.4274	-0.2096	0.0905	0.8425	-0.2624	0.8686	-79.7833	-47.8344	36.9845
31	1.5248	-1.362	0.1789	1.2304	-0.0918	0.3921	-0.084	-0.0125	-0.3931	-0.1033	0.0964	0.3994	-0.0475	-0.2404	-0.0001	0.6513	-0.0137	-0.0271	1.128	-0.1799	0.6502	-80.4818	12.7315	37.7649
32	0.1213	-0.0137	-0.2805	0.4181	0.2689	1.8389	0.0124	0.1951	0.0719	-0.1393	0.0062	-0.1095	0.1179	0.0328	-0.0043	0.9521	0.0822	0.1541	1.5793	-0.0915	0.7467	-60.3972	-42.9588	-6.9005
33	1.228	-0.2469	-0.1607	1.4123	0.2372	0.7235	-0.055	-0.1663	0.0702	0.2684	-0.0169	0.3339	0.1642	-0.1856	0.0745	0.7973	-0.4582	0.3167	1.1533	-0.3868	1.014	-132.5477	-57.7695	86.9175
34	0.3929	-0.246	-0.1163	0.1398	0.0328	0.0316	0.1609	0.0366	0.1256	0.0211	-0.1111	-0.027	-0.0482	-0.0239	-0.0604	0.4295	-0.1797	0.0397	0.8196	-0.1087	0.976	-54.7504	-40.3637	41.092
35	0.3354	0.0092	-0.3517	0.368	0.0731	1.0168	0.0274	-0.1517	-0.0928	0.1767	-0.0989	0.0985	0.0539	-0.0196	0.0566	0.4074	-0.1081	0.0678	0.465	0.0021	0.3664	-2.8143	-3.8805	124.427
36	0.5448	-0.0151	0.0152	0.6709	-0.2226	0.5408	0.0601	0.0932	0.289	0.0458	-0.0073	-0.0786	-0.2255	-0.0285	-0.053	0.4016	0.0566	0.0963	0.35	0.131	0.551	32.0674	61.3656	38.9489
37	0.3316	-0.0173	-0.0698	0.1855	-0.0665	0.3614	0.0122	-0.093	-0.0492	0.0696	-0.0299	-0.1413	0.0256	0.1905	0.0247	0.2801	-0.0186	-0.0254	0.4008	0.0453	0.3983	92.5962	-24.6016	73.4262
38	0.5148	0.1352	0.1386	1.0188	-0.1768	0.6491	0.0834	0.1292	-0.2964	-0.0779	0.0636	-0.0491	0.4388	-0.0148	-0.1471	0.7019	-0.087	-0.069	0.4109	-0.2711	0.7533	24.4069	-93.161	30.1574
39	0.3025	0.0989	-0.2349	0.7876	-0.5752	1.0818	0.0647	-0.0495	0.0817	-0.0599	-0.1418	-0.2903	-0.0487	0.2173	0.0994	0.3087	-0.0008	0.079	0.5393	0.1003	0.4579	105.7876	12.3025	12.4616
40	0.7677	-0.1822	-0.2676	1.1037	0.3861	1.3269	-0.0556	0.0997	0.0228	-0.1287	-0.0117	-0.1251	0.1021	0.0092	0.0673	0.2972	-0.016	0.0295	0.3366	-0.0149	0.2655	75.6517	-31.2152	16.8851
41	0.6686	-0.5778	-0.2419	1.2144	0.3447	0.4178	-0.0133	-0.2525	-0.2168	0.4242	-0.034	0.1108	0.0759	-0.0018	0.0583	0.7154	-0.1963	0.0761	0.7546	0.1937	0.3919	28.7496	-39.8177	161.2143
42	1.6593	-0.5365	-0.4036	0.5194	0.075	0.3231	0.0542	0.3914	0.2922	-0.1472	0.0153	0.0115	-0.0829	-0.1738	-0.0908	0.4227	0.1051	-0.0152	0.7456	0.2389	0.4344	20.3285	33.2489	-8.6573
43	1.0153	-0.2193	0.2234	0.8308	-0.1876	0.4319	-0.0135	0.1776	-0.1026	-0.3177	-0.0347	0.2413	-0.0505	-0.2104	0.0509	0.4248	-0.1023	-0.1433	0.7212	-0.037	0.4607	11.2323	-26.936	12.5597
44	0.7465	-0.1204	0.0606	0.6243	0.0774	0.6815	0.1304	0.0844	-0.4212	-0.0361	0.0278	0.2639	0.1853	-0.4572	-0.1047	0.4687	-0.2093	-0.1266	0.7269	-0.1145	0.9167	-12.5408	-78.8392	29.804
45	0.243	0.1109	0.0891	0.6805	-0.0921	0.8722	-0.0062	-0.0457	-0.1101	0.2894	-0.0653	-0.1494	0.063	0.2436	0.074	0.4115	-0.0168	-0.0647	0.4647	0.1327	0.3628	71.3705	-54.9826	111.5666
46	0.8694	0.1811	0.3093	0.1381	0.0593	0.6047	0.0959	0.2972	0.246	-0.0352	-0.0451	-0.0128	0.0335	-0.0134	-0.0497	0.3882	-0.0233	0.0623	0.5964	0.081	0.3481	68.3821	14.4278	-15.6481
47	0.2216	-0.0813	-0.0276	0.0481	-0.073	0.3556	0.0337	-0.2046	-0.1272	0.1051	-0.0004	-0.007	0.0579	0.0127	-0.0425	0.4813	-0.1339	-0.0328	0.4914	0.1527	0.3182	42.3991	-32.1136	127.6744
48	0.1013	-0.0476	0.0742	0.3593	0.0642	0.2672	0.0897	0.3544	0.2132	-0.0139	-0.0299	0.0585	0.0276	-0.0887	-0.102	0.2279	0.0631	0.0264	0.3958	0.1606	0.3179	55.8699	30.3119	12.3642
49	0.0902	-0.1022	0.0511	0.7615	0.4266	0.698	0.1188	0.0161	0.1586	-0.024	-0.0411	-0.1318	-0.1213	0.1771	-0.0781	0.3841	-0.1152	-0.0046	0.3166	0.0196	0.4736	73.1879	40.6367	67.9066
50	0.7717	0.0639	-0.1122	0.3171	0.1282	0.3698	-0.071	-0.0556	-0.2156	0.0779	-0.0009	0.0014	0.1098	0.1202	0.1056	0.2998	0.0115	0.0374	0.3091	0.0733	0.4297	80.847	-49.7271	65.5019
51	1.6141	-0.0511	0.5365	0.5852	-0.2083	0.7728	0.0066	-0.1695	0.2096	0.1774	-0.0103	0.0145	-0.07	-0.0313	-0.0108	0.5357	-0.0792	0.0348	0.4277	-0.1394	0.5302	36.9549	61.9768	112.0062
52	1.7341	0.4258	-1.0109	0.7505	-0.5011	1.0745	0.1193	-0.1069	0.1496	0.2097	-0.1002	0.068	-0.0608	-0.0552	0.0033	0.5276	0.0462	0.1171	0.5765	-0.207	0.5013	-15.1054	52.1345	118.8755
53	2.3912	-1.5306	-1.19	1.0141	0.8851	1.0013	-0.1532	0.1236	-0.3126	0.2891	-0.0315	0.1134	0.1025	-0.487	0.1763	0.711	0.0574	0.2162	0.9435	-0.2195	0.744	-48.2121	58.4465	133.6912
54	0.4823	0.2432	-0.3071	0.8137	-0.0712	0.5444	0.0273	0.2782	0.0415	-0.095	0.1021	0.1464	0.1524	-0.1109	-0.1242	0.3738	0.0037	-0.005	0.6891	-0.0506	0.2364	48.7058	-14.0481	-4.7673
55	0.2245	0.2362	-0.3322	0.3118	-0.3454	0.882	-0.1301	0.1133	-0.0573	-0.1921	-0.0053	0.0661	0.2198	-0.1224	0.1309	0.4144	-0.0471	-0.0368	0.4565	-0.1575	0.4068	46.1137	-54.8249	29.4905
56	0.9259	0.2218	0.3723	2.4798	0.1592	2.6764	-0.0153	-0.1978	0.3583	-0.0738	-0.0862	-0.0464	-0.6937	0.0622	0.1041	1.0266	-0.0452	-0.045	0.4758	-0.2682	0.7143	24.0954	89.8904	118.9684
57	1.3151	0.2581	0.0837	1.6036	-0.2492	0.2179	0.1746	0.2994	0.325	-0.2198	-0.1233	0.2402	-0.0107	-0.0511	-0.0536	0.3595	0.1375	0.0573	0.4276	0.0325	0.5207	-7.8707	45.595	48.5503
58	0.9055	-0.6337	0.3736	0.4405	-0.2637	0.1525	-0.0328	0.107	0.5112	-0.1349	0.0721	0.0527	-0.4345	-0.2848	0.0303	0.7411	0.1325	0.1311	0.4736	0.1255	0.8916	-5.1838	81.4048	57.39
59	0.4704	-0.3849	0.1387	0.4828	0.1088	0.5883	-0.0233	-0.2381	0.0146	0.2268	0.073	-0.1704	-0.0096	0.0629	-0.0232	0.5499	-0.1676	-0.0072	0.6899	-0.1356	0.3137	52.5032	24.9511	143.4962
60	0.9603	-0.0842	-0.0646	0.7902	-0.0571	0.8323	-0.0246	-0.2464	0.1196	0.1947	0.0604	-0.2215	-0.1883	0.2657	-0.0253	0.4244	-0.1566	-0.1053	0.7229	-0.0209	0.4391	101.0283	11.7351	114.1712
61	0.787	-0.1953	0.2059	1.1122	-0.0811	0.7725	-0.0665	-0.51	0.0528	0.3856	-0.033	0.0195	0.0617	-0.1347	0.0918	0.8617	-0.0419	0.2308	0.9286	-0.1209	0.3819	-7.6423	27.5591	173.9537
62	0.1329	0.234	-0.0505	0.8401	-0.4197	0.5143	0.0314	-0.0274	-0.1669	0.0609	-0.0458	-0.1029	0.1262	0.1242	0.04	0.3258	-0.0109	-0.0928	0.4179	0.0979	0.462	66.5552	-54.0495	83.8665
63	0.015	0.1438	0.0363	1.5879	-0.0052	0.3868	0.0094	-0.0254	-0.2522	-0.1661	-0.0084	-0.2896	0.0517	0.0314	-0.0168	0.3612	-0.1184	-0.0484	0.5188	-0.0705	0.5572	56.0458	-56.0865	51.2601
64	0.5711	-0.2817	0.6207	1.3977	-0.3602	2.9027	0.1291	-0.2036	0.042	0.1401	-0.0013	0.4803	0.0983	-0.3675	-0.0529	0.4858	-0.0859	0.2566	0.7956	-0.0756	0.5267	-32.4623	23.3968	152.8024
65	2.3928	1.0048	-0.1185	3.2299	-0.0859	2.2716	0.0628	-0.0959	0.2453	-0.0641	-0.0361	-0.327	-0.3448	0.2126	-0.0404	0.4448	-0.0458	0.0945	0.2845	-0.0368	0.5753	43.9489	72.2272	81.2016
66	1.8898	-0.02	0.4883	0.1243	-0.0535	0.6469	-0.025	0.1596	0.0915	-0.0012	-0.0931	-0.0862	-0.0273	0.321	0.1012	0.2627	-0.0361	-0.0016	0.4077	0.0842	0.36	89.6973	-0.0082	57.7615
67	1.3428	0.2043	-0.4717	1.3932	0.2012	1.5418	0.0675	0.1147	0.0353	0.1529	-0.0256	-0.1761	0.1065	0.0204	-0.034	0.2493	-0.0156	0.0446	0.3865	0.0925	0.3203	81.4143	14.4664	22.262
68	1.2633	0.1641	-0.959	0.1612	-0.4134	1.2809	-0.0722	-0.2867	0.0087	0.0729	-0.0255	0.0052	0.0288	0.0209	0.0994	0.6241	-0.1072	0.1437	0.6605	-0.1672	0.3804	6.1455	27.53	144.5716
69	0.2948	-0.2211	-0.0237	1.2132	0.1679	0.2442	-0.0158	-0.2752	-0.0122	0.2022	0.069	-0.1916	-0.0129	0.0769	-0.067	0.5108	-0.0511	-0.084	0.7538	-0.0204	0.2867	73.467	-0.6574	141.9042
70	0.6758	-0.626	-0.221	0.6534	0.4611	1.0218	-0.0745	-0.0749	-0.4184	0.3278	-0.0784	0.1278	0.3126	-0.3205	0.1526	0.6752	-0.1966	0.0069	0.5253	0.2058	0.5095	36.6504	-63.7183	127.5226
71	0.4194	-0.3294	0.2083	0.9005	-0.3082	0.82	-0.0025	-0.063	0.1678	0.116	-0.0118	0.0303	0.0885	0.012	0.0012	0.3583	-0.1055	0.0014	0.415	-0.0129	0.3315	53.399	2.7701	118.0018
72	1.1104	-0.3089	-0.186	3.0261	-0.0363	2.2062	-0.0515	-0.2089	0.1492	0.4081	-0.0393	0.1016	-0.3597	-0.2033	0.0735	0.8019	-0.1172	0.0403	0.8751	-0.3834	0.4916	28.9093	61.8794	155.4674
73	1.5023	-0.4381	-0.216	0.3449	0.1456	0.2497	0.0972	0.374	0.0902	0.0573	-0.1767	-0.0546	-0.0831	-0.0818	0.0475	0.4843	-0.1341	0.0192	0.6603	-0.0108	0.3163	59.2145	24.0131	112.2513
74	0.6084	0.2777	0.8715	1.7427	-0.405	1.6479	0.0663	0.1243	-0.1096	-0.1264	0.247	0.2057	0.0513	-0.1288	-0.2774	0.4161	0.0792	-0.0953	0.8563	0.1696	0.3856	7.3728	17.4367	3.1107
75	1.1176	0.5224	-1.4331	1.1787	-1.2939	2.2547	0.1287	-0.1157	0.0818	0.1433	-0.0729	0.0167	-0.0517	0.0091	-0.0128	0.5513	-0.0616	0.125	0.5529	-0.1061	0.8216	-35.4749	5.4256	82.5281
76	0.4183	0.4333	0.2444	1.8548	0.7098	1.5178	-0.0198	-0.0483	-0.1854	0.0306	-0.0026	0.2496	0.3454	-0.2509	0.0308	0.4838	-0.1345	0.0098	0.4095	0.0247	0.509	20.3436	-60.9381	77.2358
77	0.8883	0.0659	-0.0711	0.8169	-0.0296	1.2934	0.1969	-0.2914	-0.0511	0.307	0.0076	0.23	-0.2413	-0.29	-0.1754	0.3827	-0.1062	0.1861	0.5911	-0.1138	0.4872	-17.7057	13.9442	123.702
78	0.8378	-0.1664	-0.3762	0.0671	-0.0804	0.8196	-0.1176	-0.0677	-0.2108	-0.1572	-0.1801	-0.2234	0.2794	0.2419	0.2516	0.5326	0.1608	0.3532	0.7351	0.3521	1.4315	294.955	-0.9281	218.6223
79	0.9182	0.5486	0.0668	1.3201	0.0446	0.7363	0.0731	0.3557	-0.2348	-0.4017	-0.103	-0.2515	0.1435	0.1257	0.0374	0.6076	0.1852	0.1949	0.674	-0.1907	0.7053	238.8651	-24.7448	177.6624
80	1.3706	-0.4977	0.0877	1.1001	-0.0321	1.4121	0.0297	0.0205	-0.0589	0.0675	-0.1628	-0.1229	0.0788	0.2962	0.1412	0.4163	-0.043	-0.0787	0.5375	0.2152	0.8957	277.4882	17.5629	248.1567
81	0.9689	0.0562	-0.4671	0.6415	0.0394	0.7305	0.2767	-0.3318	0.3013	0.2068	-0.0643	-0.0799	-0.2857	0.2345	-0.2231	0.6603	-0.0501	0.0508	0.519	-0.0686	0.7377	273.9662	-22.6306	279.2549
82	0.6374	0.0842	-0.4892	0.723	-0.1368	0.798	0.0046	-0.0589	0.2539	-0.0072	-0.0068	-0.5162	-0.2035	0.2312	-0.0127	0.5851	-0.1543	-0.1619	0.3888	0.135	1.1142	252.8016	88.3273	245.1024
83	1.0883	0.5794	-0.1507	0.6644	0.0454	1.9622	-0.1919	0.5156	0.0169	-0.1908	0.1285	-0.1076	0.4584	-0.304	0.0043	0.9341	-0.0976	0.1527	0.6379	0.0645	0.4886	255.1609	-69.5549	231.8059
84	1.3035	-0.0752	-0.2791	0.7822	0.0186	0.5332	-0.0057	0.0612	0.2905	0.3821	-0.1053	-0.0721	-0.2806	-0.106	0.08	0.8523	0.1005	-0.1292	0.3107	-0.0514	0.7014	197.2282	103.9055	256.4512
85	1.1564	-0.1617	-0.1588	0.6756	0.1917	0.9667	-0.0119	0.1864	-0.0016	-0.2906	-0.2396	-0.3869	-0.2206	0.3642	0.2115	0.5638	-0.0924	0.2282	0.9155	0.3341	0.9821	285.818	53.6038	187.5367
86	0.3757	0.27	-0.1736	1.1638	-0.1387	0.6699	0.0282	0.1887	0.3129	-0.2707	-0.1412	-0.0443	-0.229	-0.0328	0.1012	0.6352	0.0531	-0.0646	0.3896	0.1933	0.5893	210.3437	92.7376	211.4182
87	0.6899	0.1737	0.0151	0.8454	0.0305	1.2829	-0.0119	-0.1533	0.216	0.2631	0.0049	-0.3044	-0.0236	0.207	-0.0577	0.5353	-0.0227	-0.3348	0.5078	0.0362	0.9656	265.6318	50.5826	273.0922
88	0.3271	0.3919	0.3972	0.6053	0.1569	1.2119	0.1688	-0.4691	0.2592	0.3132	-0.2301	0.0548	-0.0619	0.1511	0.0181	0.9993	-0.1018	0.145	0.9095	-0.2573	0.8434	257.0661	-26.9182	309.0258
89	1.1563	-1.0567	0.4251	2.0532	-0.6256	0.7372	-0.0439	0.3839	0.1523	-0.3647	-0.0869	-0.2627	-0.2272	0.0764	0.0953	0.6176	-0.0587	0.1068	0.4661	0.198	0.6491	233.4145	72.0483	208.1155
90	1.2395	0.2753	-0.1186	0.8026	0.6462	0.6219	-0.0528	-0.1429	0.1851	0.1761	-0.0638	-0.1885	-0.0117	-0.0102	0.0815	2.0392	-0.3505	0.3675	1.8676	-0.3905	1.2491	246.0231	-19.2282	340.5582
91	0.6788	0.027	-0.2936	0.8576	-0.2422	0.9507	0.0648	0.1489	0.0906	-0.1811	-0.1173	-0.2347	-0.1482	0.3628	0.0012	0.4721	-0.0059	0.0752	0.5734	0.158	0.5389	248.955	33.9876	184.9064
92	0.5725	-0.0345	0.1312	1.1252	0.8112	1.277	0.2132	0.1434	-0.0731	0.1859	-0.1268	-0.0141	0.6672	0.0389	-0.1117	0.7088	0.1149	0.0849	0.5802	-0.1089	0.8537	232.479	-36.5868	199.9054
93	2.2756	0.1377	-0.451	1.6057	0.2253	1.6735	0.0389	-0.3025	0.3775	0.1494	-0.0146	0.3058	0.3263	-0.2832	-0.0606	0.6911	0.0347	0.2449	0.7196	0.1737	0.6711	215.5792	-59.5689	295.6145
94	1.4029	-0.3339	-0.6227	1.4179	0.5651	0.8651	-0.1449	0.0364	0.0953	-0.0382	0.0982	-0.2857	0.2966	0.1019	0.0555	0.6689	0.1204	0.1584	0.3727	0.1053	0.6043	273.9835	-70.6169	252.1335
95	0.2369	0.4201	-0.506	0.7676	-0.9675	1.3643	0.1903	0.2108	0.0872	-0.2812	-0.2286	-0.3547	0.0337	0.0542	0.0762	0.5754	0.2425	0.23	0.6645	0.1986	0.9519	294.1918	-25.0503	230.7227
96	0.8024	-0.0642	-0.1551	1.5387	0.0956	0.4785	-0.0028	0.2736	-0.0095	0.0284	0.1065	0.1975	0.3462	-0.4177	-0.1014	0.8313	-0.201	0.0041	0.7421	0.2853	0.5913	221.4989	-80.6323	269.0761
97	1.4619	-0.33	0.224	1.7455	-0.2726	0.8857	-0.2071	-0.1412	-0.4214	0.1473	0.1793	-0.0679	0.5551	0.0158	-0.0116	0.9452	0.0865	0.1095	0.4378	0.111	0.8309	254.8298	-87.441	271.2325
98	1.3907	-0.5036	0.5021	1.6057	-0.3219	1.6665	0.1766	-0.2562	0.1084	0.2819	-0.0271	-0.1171	-0.0149	0.3837	-0.1541	0.6033	0.0982	-0.0448	0.6073	0.0376	0.62	280.6606	-49.8072	284.0014
99	1.4058	-0.1611	0.2937	0.0215	0.0262	1.1276	-0.0445	0.0309	0.1106	-0.118	-0.0998	-0.4043	0.0378	0.3424	0.0815	0.3974	0.0362	0.0966	0.7651	0.3702	1.3537	292.3394	19.489	225.9288
100	0.4494	-0.1421	0.089	0.3806	-0.2104	0.5742	0.0617	0.0031	0.2154	0.0412	-0.1443	-0.2779	-0.0075	0.188	0.0954	0.3765	-0.0892	0.0742	0.5487	0.2196	0.9228	271.112	39.4938	220.2456
101	0.5424	-0.0264	-0.1263	0.6721	-0.26	0.4095	-0.0548	-0.031	-0.0026	0.1175	-0.069	-0.1668	0.0972	-0.0093	0.1089	0.3587	0.0069	-0.0499	0.2724	0.0485	0.444	227.0869	27.9647	257.7273
102	0.7472	0.3525	0.3351	0.63	0.1182	0.6306	0.0538	-0.3826	0.1319	0.4105	-0.1043	-0.4188	-0.2757	0.0947	0.0113	0.9445	-0.0755	-0.3694	0.4395	-0.1226	0.8242	239.247	85.6269	280.756
103	2.7004	1.1539	0.2376	1.9016	0.5039	2.2593	-0.1337	0.2901	-0.4127	-0.126	-0.0002	0.014	0.2996	-0.1147	0.1178	1.3971	-0.2852	0.2451	0.5383	0.0386	0.7451	239.9123	-93.7907	239.5132
104	0.6036	0.27	0.2913	0.4063	0.234	0.9455	0.0029	0.0936	-0.5571	-0.0229	-0.0063	-0.1119	0.2296	0.2832	-0.0139	0.4967	0.0902	0.0561	0.5318	0.0288	0.9288	246.6193	-18.1816	209.3304
105	1.3986	0.0873	-0.2152	1.3674	0.2305	0.0785	-0.049	0.5766	-0.0012	-0.3722	0.0515	-0.1182	-0.053	0.1935	0.0514	0.6067	0.0007	0.2771	0.9359	0.1162	0.7529	270.9806	21.7749	180.4467
106	2.0401	0.1982	0.13	1.831	-0.0289	3.1417	0.0146	0.5491	-0.0138	-0.4725	-0.0486	0.0373	-0.135	-0.0773	0.0168	1.1482	-0.1293	0.22	0.9969	0.1522	0.5763	258.2704	-49.6664	215.3418
107	2.5045	-0.0529	-0.6654	1.5058	0.1057	0.4609	0.0161	-0.4667	0.2369	0.0153	-0.0558	-0.0899	-0.0085	0.0444	0.0612	0.691	0.1506	-0.0103	0.5692	0.0395	0.5963	252.1558	-39.9819	285.6782
108	2.2437	1.5706	0.12	1.5987	0.4518	0.6239	-0.1305	-0.1202	-0.4244	0.5678	0.0592	-0.5999	0.024	0.1686	0.0937	0.8609	-0.0531	-0.2498	0.5701	0.3034	0.8125	249.112	21.1654	281.9757
109	0.4166	0.0575	-0.312	0.7695	-0.9777	1.3783	-0.0187	-0.1668	0.1761	0.1343	0.0169	-0.0137	0.1274	0.1934	-0.0224	1.7152	-0.2213	0.2943	1.6743	-0.2944	0.9559	227.5707	-34.1922	323.4367
110	1.1434	0.3725	-0.2482	1.0869	0.0713	0.979	0.0657	0.2336	0.1134	-0.1794	-0.0082	-0.6389	0.3823	0.5853	-0.0789	0.7417	0.4009	0.2409	1.0316	0.0904	1.2779	310.5825	-52.9424	243.2418
111	0.9226	0.527	0.3594	0.2826	0.2066	0.1277	0.0148	-0.0928	-0.0137	-0.1262	0.0704	0.0793	0.0045	0.0219	-0.0991	0.5387	-0.0112	-0.0216	0.5021	0.0219	0.6605	217.7415	-38.9844	282.0685
112	0.6614	-0.0963	-0.6044	0.3521	-0.062	0.7426	0.0377	0.2631	-0.0989	-0.0945	-0.0551	-0.0243	0.0434	-0.1116	0.0289	0.4065	0.0245	0.0249	0.5022	-0.0989	0.3136	192.7618	-6.2721	184.7339
113	0.3851	-0.0743	0.0402	0.4217	0.0132	0.4888	0.0173	-0.0199	0.1442	-0.0138	0.0203	0.0411	-0.1676	-0.104	-0.0396	0.4083	0.0397	0.0429	0.2044	0.0483	0.4355	137.1533	66.7982	250.767
114	0.1272	-0.0443	0.1374	0.1458	-0.0037	0.5688	0.0702	0.0953	-0.0601	-0.101	0.0422	0.1456	0.1574	-0.1917	-0.0721	0.38	-0.086	-0.137	0.4123	-0.0271	0.4321	88.5894	-25.9062	214.8468
115	0.7005	0.0216	0.0209	1.3071	-0.3578	0.6938	0.0058	-0.0418	-0.1994	0.1317	0.0931	0.2182	0.1057	-0.0998	-0.1044	0.516	-0.0217	-0.1309	0.2583	0.1283	0.4858	145.502	-84.5858	281.8731
116	0.5747	-0.2921	-0.5852	0.7681	0.6758	0.9881	0.1407	0.019	-0.1352	0.0492	-0.1445	0.1893	-0.0206	-0.37	0.023	0.3362	0.0381	0.0441	0.4855	0.1565	0.4221	60.5594	17.1648	265.9546
117	0.7087	-0.0313	-0.331	0.9379	-0.2243	0.7673	-0.0583	0.0478	-0.0855	0.0651	0.1191	0.1866	0.0654	-0.1493	-0.0451	0.3734	-0.0641	-0.0199	0.2612	0.1164	0.3399	91.9771	-24.8456	274.1436
118	0.432	0.3094	0.0726	1.0597	0.1378	0.4162	0.0443	0.3493	-0.2094	-0.1649	-0.0208	-0.0644	0.1856	-0.0422	-0.005	0.8293	0.1111	0.0414	0.8547	-0.34	0.4556	171.2402	-48.1736	146.8128
119	2.1105	0.6996	-0.3605	0.5728	-0.0139	0.3113	-0.044	-0.1626	0.0618	0.1343	0.0615	-0.0369	-0.0988	-0.1234	-0.0343	0.5192	0.075	-0.0082	0.3291	-0.0343	0.2862	138.4234	44.9894	303.2107
120	0.2199	-0.1457	-0.1138	0.6127	0.4771	0.3749	-0.1791	-0.0911	0.0049	0.5444	-0.0197	-0.2156	-0.1042	0.0355	-0.254	0.9285	0.0743	-0.3777	0.2731	-0.0841	0.4606	154.7681	-15.904	291.4985
121	1.565	-0.193	-0.231	0.5335	-0.0033	0.8294	-0.1472	-0.0662	0.0685	0.1251	0.1366	-0.174	0.1429	0.1502	-0.0093	0.5369	0.0226	-0.1515	0.2217	-0.0113	0.5129	181.5779	-69.0602	288.2244
122	1.2162	0.7521	-0.1502	3.3173	-0.0654	1.1999	0.0467	-0.22	-0.3046	0.2914	-0.1603	-0.092	0.4227	0.2315	0.1203	0.9599	-0.2819	-0.2697	0.6527	0.1889	1.4064	173.5322	22.4834	347.5143
123	0.2583	-0.0844	0.0178	0.6858	0.0226	0.852	-0.0112	0.1931	-0.13	-0.2229	0.0605	-0.0268	0.2181	0.0024	-0.0542	0.548	-0.0989	-0.1243	0.5258	-0.1426	0.4142	118.9531	-59.5907	186.8549
124	0.8546	-0.3141	0.4465	0.1771	-0.2825	0.9372	-0.0661	-0.1514	0.0778	-0.0687	0.0903	0.047	0.0142	-0.2019	-0.0119	0.3721	0.0338	0.0901	0.3123	0.0724	0.329	90.5299	25.0044	301.4752
125	0.0948	-0.0608	0.0369	0.1115	0.0188	0.2744	0.09	0.2302	-0.1719	-0.1505	-0.0016	-0.083	0.1286	-0.0046	-0.0957	0.6326	0.0151	-0.0759	0.5741	-0.2382	0.4135	150.3195	-37.191	175.0394
126	0.4666	0.1577	0.0376	0.3328	-0.068	0.3635	-0.0361	-0.0904	-0.0119	0.0407	0.029	0.0521	-0.035	-0.1351	0.008	0.2443	0.0376	0.0565	0.1509	0.0544	0.1324	108.7724	37.9869	275.0522
127	1.2695	-0.0368	0.7595	0.8006	-0.2666	0.9175	0.1288	0.2166	0.1828	-0.1332	-0.0728	0.2848	-0.0837	-0.144	-0.0644	0.3543	0.0643	-0.0038	0.3001	0.1427	0.3373	110.2914	41.506	211.6595
128	0.5968	-0.0189	0.0559	0.3986	0.0569	0.3273	0.0417	-0.0726	-0.2344	-0.1481	-0.0479	0.0591	0.1757	-0.1237	0.0031	0.4931	-0.1452	-0.1076	0.344	0.0336	0.4344	98.662	-49.2392	228.4613
129	0.502	0.3641	-0.1632	0.6066	0.1901	0.3661	-0.1223	0.0875	0.185	-0.2672	-0.029	-0.1064	-0.0868	-0.0399	0.1563	0.6343	-0.005	-0.0456	0.5324	0.1774	0.3334	149.4356	58.3809	179.1742
130	1.9666	-1.0407	-0.9479	0.7598	0.8102	1.2095	0.1494	0.2083	0.2631	-0.126	0.0477	-0.103	-0.2346	0.0943	-0.1545	0.3644	-0.0757	0.0527	0.544	0.1611	0.4594	201.7491	50.8624	185.6411
131	2.9839	1.3517	0.3245	0.7315	0.0839	0.0676	-0.1866	0.3187	0.0304	-0.0844	0.0003	-0.2825	-0.0897	0.3586	0.1728	0.6617	-0.0507	0.0894	0.9456	0.2005	0.5968	236.8183	61.2784	178.8179
132	0.4663	-0.0738	-0.1433	0.7429	-0.0381	0.3532	0.0522	-0.0784	-0.0096	0.2171	0.0184	-0.0609	0.0628	-0.0669	-0.068	0.4166	0.0271	-0.0305	0.3004	0.0663	0.2467	112.7167	-3.6476	299.1155
133	0.291	-0.264	-0.2794	0.3319	0.4112	0.5079	0.0128	-0.0571	-0.1742	0.2075	0.0438	0.0485	0.1272	0.055	-0.0417	0.5288	0.0115	-0.0659	0.2577	0.0643	0.4071	124.2945	-47.8333	272.0087
134	0.4547	-0.6195	-0.0206	1.8561	-0.6434	2.4156	0.0261	0.2845	0.2189	-0.1904	0.0739	0.0835	-0.3651	-0.1727	-0.1161	1.0627	-0.1179	-0.035	0.7059	0.4075	0.6359	162.3375	86.0368	171.9668
135	0.8991	-0.2033	0.4821	1.6464	0.0947	0.3828	0.0836	-0.1619	0.2144	0.2329	-0.0919	-0.3338	-0.0844	0.0508	-0.0081	0.4636	-0.0791	-0.033	0.2415	0.0541	0.4114	178.4726	52.1026	252.7943
136	0.3764	0.5995	0.2418	0.916	0.3823	0.1465	-0.0259	-0.0237	0.2111	0.1409	0.0606	0.0905	-0.1497	0.0621	-0.0086	0.6839	-0.0969	0.0013	0.3703	-0.0167	0.7427	191.4861	101.0922	249.2469
137	0.3273	0.0189	-0.007	0.4381	0.2201	0.459	0.0446	0.1225	0.0056	-0.4055	-0.0921	0.1995	-0.1814	-0.1067	0.056	0.6599	-0.0418	-0.1097	0.807	0.1388	0.2834	142.6021	17.207	150.0587
138	1.0362	-0.3261	-0.0116	0.9823	-0.132	0.9531	0.127	0.3264	-0.1605	-0.2629	0.0656	0.1378	-0.0783	-0.0343	-0.1543	0.5132	-0.0046	-0.218	0.7227	0.082	0.4362	89.2437	4.6024	168.9226
139	0.3814	0.0196	0.1994	0.6521	0.0203	0.299	0.1003	0.1765	0.0985	-0.5007	-0.0181	-0.2241	0.0899	0.1287	-0.0808	0.874	-0.0684	0.2701	1.3502	0.0492	0.4457	208.3984	18.9818	134.0672
140	0.1637	-0.0517	0.0541	0.9806	0.2656	0.2205	-0.0872	0.146	-0.0714	-0.1316	0.1585	0.1606	0.1274	-0.0322	-0.066	0.5114	-0.107	-0.1392	0.3959	-0.0681	0.4037	116.9395	-54.9665	214.5651
141	0.0061	-0.0428	-0.032	2.7691	-0.3256	0.3917	0.0652	0.0305	-0.1896	0.1251	-0.0714	0.4125	0.1477	0.0406	0.0087	0.5112	0.0342	-0.1554	0.3071	0.0407	0.5357	119.4687	-52.3993	248.896
142	1.3384	0.3052	-0.7042	1.4356	0.7328	2.1653	0.1061	0.2249	-0.0698	-0.0008	-0.0298	-0.3474	0.1359	0.6586	-0.0452	0.4293	0.0555	0.1188	1.0482	-0.0372	0.5241	227.9752	19.0362	161.0445
143	2.2623	-0.6863	0.1323	3.0285	-0.0468	2.186	-0.1537	0.2257	0.0686	-0.1379	0.1281	0.3566	-0.2912	-0.2857	0.0238	0.3941	0.003	0.0123	0.3817	0.1875	0.3673	135.0834	72.0082	205.9351
144	1.8687	0.1302	0.9635	0.1894	0.1882	1.2339	0.0927	-0.0433	-0.197	0.0067	0.0317	0.0876	-0.1229	-0.374	-0.1158	0.3142	-0.0192	-0.055	0.4203	0.1011	0.3564	87.1688	0.5164	227.4717
145	2.0009	-0.3665	-0.3768	1.9723	-0.0927	1.8567	-0.0835	0.1525	-0.0722	-0.0922	0.0405	0.1169	0.0506	-0.3392	0.0212	0.2114	0.0007	0.0163	0.2982	0.0622	0.2683	86.5217	19.6957	261.8259
146	1.0886	-0.0786	-0.5056	0.1821	0.1375	0.589	-0.156	0.2357	-0.1708	-0.0851	0.0813	0.1054	-0.0208	0.1314	0.0791	0.6276	-0.0057	0.1145	0.7671	0.0847	0.2601	188.0413	21.9076	159.291
147	0.3931	0.1436	0.1219	0.786	-0.1836	0.4503	-0.0285	0.4334	-0.0572	-0.2698	0.0819	0.0633	0.0215	-0.0286	-0.0915	0.5941	-0.0663	-0.1923	0.9535	-0.0321	0.3482	122.8105	-9.4114	150.0005
148	1.0301	0.5884	-0.3226	0.372	-0.1806	0.6148	-0.0957	0.0899	-0.2766	-0.1998	0.0487	0.016	0.2534	0.1972	0.062	0.8292	0.0917	-0.0769	0.5536	-0.2741	0.4922	156.7097	-68.1745	180.583
149	0.6577	0.7319	0.3687	1.5353	0.6049	0.8366	0.0239	0.3214	-0.0118	-0.1059	-0.0546	-0.0767	0.0699	-0.1541	0.0203	0.4789	-0.0071	-0.0266	0.5642	-0.0453	0.2618	136.476	-2.0899	177.2501
150	0.6967	-0.0533	-0.3579	1.8712	0.0097	1.8507	0.0984	0.0167	0.1153	-0.4419	-0.0694	-0.143	-0.1302	0.2338	0.0101	0.7541	-0.0699	0.049	0.9557	0.281	0.3539	167.2584	53.318	139.1661
151	1.1931	-0.0117	0.1306	0.5457	-0.0251	0.5542	0.1225	-0.1101	0.0693	-0.1405	-0.0607	0.1537	-0.0361	0.2467	-0.0552	0.5269	-0.0084	-0.0846	0.6669	0.0996	0.4316	128.848	19.3624	178.6428
152	0.8893	-0.3243	-0.0108	1.7719	0.6932	2.0499	-0.1281	-0.086	-0.1059	-0.0726	0.0174	0.052	0.1714	0.0845	0.1243	0.4708	0.0038	-0.0578	0.2708	-0.0162	0.3028	154.0189	28.8017	296.5286
153	1.2833	-1.568	-1.1391	1.9157	1.3927	1.012	0.0481	-0.0018	0.1844	-0.1072	-0.1852	0.0694	-0.1361	-0.1062	0.1293	0.3101	-0.0241	0.0184	0.4066	-0.0144	0.7934	214.5907	10.0028	229.7123
154	0.395	-0.4105	0.3176	1.4774	-1.1967	2.0941	-0.0465	0.0311	-0.0517	-0.0274	-0.0332	-0.322	0.3123	0.1696	0.0598	0.5729	0.0656	-0.1008	0.3434	-0.1016	0.4218	160.2114	-58.7247	232.6198
155	1.0091	-0.1594	-0.5774	0.9168	0.573	2.0298	0.0541	0.33	0.111	-0.3835	0.1661	-0.3045	-0.2215	0.1159	-0.1793	0.3671	-0.017	0.0914	0.4722	0.0141	0.3359	206.5432	12.5185	186.5407
156	1.7675	0.2821	-0.3997	0.8083	-0.4664	1.5246	-0.0611	-0.4567	0.1248	0.4477	-0.2165	0.0695	-0.2404	0.0297	0.2532	1.2477	-0.2261	-0.0057	0.8035	-0.0256	0.5749	134.5187	15.7006	350.5264
157	2.7928	-0.0263	1.7841	2.2624	0.6201	1.3189	-0.0505	0.1816	0.2951	-0.0627	-0.0207	-0.2945	-0.1852	0.2539	0.0609	1.8938	-0.1812	0.2737	2.0096	-0.05	1.7287	117.7136	15.9481	369.4184
158	0.0102	0.0483	-0.0386	0.3901	-0.2917	0.2212	0.1261	0.2132	0.1121	-0.1668	-0.0131	0.3253	-0.12	-0.3498	-0.1029	2.006	-0.003	0.5189	2.2124	-0.045	2.0498	102.881	13.0934	378.0963
159	0.2198	-0.0052	-0.0447	0.1161	-0.0194	0.1518	0.0437	-0.0187	0.0314	0.0408	-0.0329	-0.0064	-0.0173	-0.0021	-0.0141	0.3241	-0.0552	-0.0162	0.337	0.003	0.3593	39.4451	2.1006	75.9437
160	2.9769	0.9037	-0.2392	0.2745	-0.0711	0.021	-0.2049	-0.0606	-0.4072	0.1229	0.3014	0.3883	0.1676	-0.3953	-0.0788	0.8436	-0.3448	-0.0428	1.3708	0.041	1.2844	-17.2225	-48.8476	15.304
161	0.5869	0.3216	0.7197	1.1417	0.0361	1.0168	-0.3182	-0.1399	0.2379	-0.1046	-0.0879	0.9781	-0.0578	-0.5131	0.392	1.2667	0.1836	-0.1583	1.5166	-0.1821	1.3181	-2.4626	-0.1548	-24.6809
162	0.7638	-0.4925	-0.5369	0.6754	0.0564	0.8432	-0.1486	-0.9365	0.5858	0.7834	-0.3577	-0.0573	-0.6539	-0.4084	0.4683	1.3717	0.0218	0.1222	1.3362	-0.248	1.0266	28.3701	0.7215	156.0745
163	0.5735	0.07	-0.3731	1.7257	-0.5519	1.5115	0.2054	-0.0222	-0.0788	-0.1407	0.0805	0.2136	0.1282	0.0887	-0.2262	0.6616	-0.021	0.0674	0.8249	-0.1544	0.7523	-29.7734	-15.7979	61.9896
164	0.0124	0.0008	0.0092	0.0005	0.0015	0.0079	0.003	-0.2465	-0.7549	0.1048	0.1301	0.8869	0.9474	-0.9027	-0.1185	1.5438	-0.3366	0.0972	2.0263	-0.3321	1.8874	-21.3847	-27.6915	163.8511
165	2.2001	-1.0524	-1.466	3.7401	-1.8376	2.9873	0.1896	-0.7103	0.4874	0.8767	0.0334	-0.7841	-0.4248	0.4748	-0.213	1.3443	-0.2466	-0.0931	1.3472	-0.0061	0.8446	12.1519	-2.5131	182.4306
166	0.1018	-0.3682	-0.2955	1.3483	1.0638	0.8599	-0.016	-0.9228	0.9894	0.648	0.4106	0.0119	-0.7757	-0.1496	-0.3941	1.2367	0.2238	0.1986	1.0402	-0.4484	1.2582	-4.7551	89.0739	101.2492
167	0.3581	0.3946	0.1936	0.8926	0.0731	0.1297	-0.0257	0.2797	-0.2305	-0.3739	0.1021	0.0337	0.1632	-0.0484	-0.0586	0.6021	-0.1242	-0.0288	0.6549	-0.2756	0.596	23.7945	-66.8019	16.7698
168	0.3483	0.0374	-0.1134	0.2451	-0.1378	0.6341	0.0535	-0.2989	0.0809	0.2255	-0.0495	-0.0553	-0.103	0.1044	0.0186	0.514	-0.1187	-0.0473	0.5987	-0.0572	0.4097	63.5498	7.6885	126.5951
169	0.3395	0.0664	-0.0705	0.3851	0.0054	0.2913	0.0426	0.112	0.1471	-0.1032	-0.0616	0.1884	-0.1692	-0.2589	0.0263	0.5126	0.1891	0.0116	0.6842	-0.0151	0.6564	-54.4157	63.4539	63.2087
170	2.1117	1.597	-1.0378	5.2679	2.0394	3.3593	-0.128	0.7532	0.5777	-0.7679	-0.0994	1.0477	-0.7033	-0.6979	0.189	1.0779	0.4126	-0.1632	1.2912	0.2062	0.9733	-49.7051	102.215	34.8065
171	2.8974	-0.5528	-0.1962	5.1155	1.0676	0.6355	0.0709	-0.2975	0.4463	0.148	0.0255	0.1422	-0.5736	-0.2724	-0.0832	1.5467	0.3175	-0.0962	1.3278	-0.253	1.728	-42.9329	127.8768	104.6879
172	2.2573	0.4703	-0.3924	0.3188	-0.696	1.7729	-0.0242	-0.0765	0.6652	0.4092	-0.0653	0.4404	-0.7267	-0.321	0.1167	1.6108	-0.0311	0.439	1.2335	-0.3787	1.6975	-59.5311	113.4542	118.7339
173	0.0765	0.3497	-0.0392	1.5958	-0.1777	0.0199	-0.2824	-0.0563	-0.3672	0.1785	-0.1507	0.4158	0.4298	-0.2763	0.3434	1.8969	-0.1027	-0.2753	1.9692	-0.1815	1.7032	-112.3943	14.6739	28.0177
174	0.6385	0.1613	0.0202	0.9268	-0.46	0.2507	-0.0306	0.1181	0.0867	-0.4564	-0.0379	0.3473	-0.0134	-0.302	0.018	0.704	0.1849	-0.1691	1.3664	-0.0142	0.8603	-83.8908	48.7106	24.9728
175	0.5245	0.0284	-0.017	0.5127	-0.0298	0.3396	0.0746	-0.1302	-0.1575	0.2934	-0.1447	0.2585	0.0666	-0.2002	0.0479	0.5618	-0.1433	0.1756	0.6728	-0.1065	0.6379	-60.6916	10.3732	106.5748
176	0.6457	0.5053	-0.337	1.2053	0.7545	1.505	0.0421	-0.0464	0.3146	-0.3002	0.3232	0.6689	-0.7352	-0.9426	-0.3417	0.9965	0.2357	0.0419	1.4456	-0.1975	2.0266	-109.2463	58.0375	97.1257
177	0.0119	0.0091	0.0069	0.0333	-0.0119	0.0224	-0.321	-0.2212	0.0365	-0.2319	0.0548	0.6744	0.0091	-0.712	0.2476	1.6444	0.1824	-0.0102	1.97	-0.2047	1.8608	-99.9291	79.4741	109.4454
178	0.0006	0.0238	-0.0166	0.291	0.0138	2.3082	0.0767	0.1476	0.1109	-0.0758	0.005	0.0909	-0.3154	0.1405	-0.1049	0.5173	0.1153	0.1347	1.0111	-0.1163	1.0565	-80.3538	56.5527	79.1512
179	0.0594	0.3848	-0.1159	2.6169	-0.8046	0.2462	0.4733	-0.0844	0.2544	0.2	-0.266	0.3493	-0.6384	-0.0252	-0.1985	1.3149	0.0505	0.3776	1.1384	-0.4005	1.2401	-64.0416	78.7829	127.5604
180	0.1352	0.1383	-0.0996	0.2888	0.1477	0.1114	0.0264	0.1065	-0.0872	0.1692	-0.141	0.0644	0.1328	-0.2321	0.0775	0.5489	-0.2384	0.0581	0.9187	-0.2667	0.9108	-74.7009	-48.0512	56.5801
181	0.6794	-0.1834	0.0319	0.1109	0.1524	0.4798	0.0562	0.1069	0.1634	-0.0863	-0.1155	-0.1803	-0.1422	-0.1478	0.0609	0.3896	0.0913	0.055	0.4889	-0.0549	0.4516	-32.8259	43.2829	72.5163
182	0.1838	0.0055	0.0071	0.1281	-0.0121	0.136	0.0181	0.1229	-0.0028	-0.0487	0.02	0.0165	0.0236	-0.0279	-0.0376	0.3799	0.0042	-0.0548	0.3236	0.0162	0.3188	139.92	3.2022	221.2414
183	2.6373	-0.1719	-0.4743	0.017	0.0494	0.1657	-0.0964	-0.3317	-0.647	0.5136	0.2576	-1.3812	0.2201	1.4198	-0.1084	1.0263	0.2282	-0.2265	1.3804	-0.0484	1.5192	183.381	-36.4192	299.0312
184	0.6205	0.4073	0.5971	0.883	0.2905	0.7289	0.2229	0.1554	0.0799	-0.0655	-0.3514	-0.4494	-0.1027	0.2442	0.1174	1.1696	-0.2783	0.0737	0.8503	0.1591	0.8093	154.6704	22.154	330.3968
185	0.6883	0.1347	-0.2372	0.2708	0.02	0.1005	-0.1908	0.9907	0.4747	-0.7218	0.2022	-0.0719	-0.4268	0.6983	0.0235	1.3436	-0.2493	0.0883	1.5161	0.0475	0.9216	170.2837	-7.3909	146.3269
186	1.4368	-0.8601	-1.3209	2.368	0.0685	1.4961	0.2193	-0.2752	-0.0938	0.279	-0.0115	-0.2476	0.2025	-0.0968	-0.2028	0.7461	-0.1264	0.0318	0.7913	0.0299	0.7355	205.6226	-10.6303	249.6413
187	0.0011	0.0009	-0.0001	0.0013	-0.0025	0.0102	0.0278	0.0281	-1.138	-0.1084	0.0483	-0.5683	1.1489	0.6866	-0.0418	2.0489	0.3561	-0.1117	1.8862	-0.1431	1.6643	221.0426	-35.1215	152.1729
188	2.4296	-0.5024	-0.2056	2.4334	-0.4844	0.1365	0.131	0.8279	0.1804	-0.8673	0.0835	0.5063	-0.1367	-0.0757	-0.2099	1.5169	0.0519	0.021	1.5035	-0.3128	0.8269	192.3762	-13.2415	125.1138
189	0.3415	0.3015	-0.4192	0.2702	-0.3715	0.5147	-0.1421	0.6331	0.874	-0.6637	0.0476	-0.0786	-0.6425	0.3196	0.061	1.1052	-0.1649	0.0624	0.9716	0.4622	1.1042	187.3085	88.8835	196.6681
190	0.2789	-0.4454	0.2334	0.8943	-0.3806	0.1314	-0.1177	-0.1141	-0.1032	0.5215	0.1818	0.0549	-0.0409	-0.1034	-0.0619	0.6213	0.0415	-0.0477	0.386	0.0704	0.4592	143.2013	-56.5236	291.26
191	0.2284	-0.0525	-0.1303	0.1386	0.1733	0.4958	0.0316	0.2954	0.0492	-0.1838	0.0277	0.0225	-0.0229	-0.0579	-0.0299	0.5906	-0.038	-0.0938	0.766	0.0342	0.3859	128.5326	1.1629	166.0356
192	0.3815	-0.1222	0.0174	0.6373	0.0582	0.2302	-0.0433	0.0082	0.2017	0.1327	-0.0482	-0.2511	-0.1953	0.0644	0.084	0.5234	-0.0773	-0.1032	0.3499	0.0714	0.6117	227.0052	69.4218	248.9589
193	2.6637	-1.3095	-1.6355	2.4113	-1.151	3.2509	0.1058	-0.8405	0.7849	0.7542	-0.3339	-0.4965	-0.439	0.5971	0.1516	1.3832	-0.091	-0.3473	0.7065	-0.1818	0.7967	214.4313	109.8093	273.4306
194	1.8406	-0.0907	0.032	2.3606	0.4312	0.0801	0.2564	0.4675	0.5482	-0.3128	0.1689	-0.267	-0.484	0.2316	-0.379	1.9124	-0.1845	-0.1032	1.2243	0.3446	1.7332	222.0758	132.1383	202.3844
195	0.0025	0.002	-0.0002	0.0055	0.0018	0.0005	0.0251	-0.0452	0.5544	-0.1945	-0.0616	-0.3403	-0.5971	0.1156	0.0362	2.1003	0.1316	0.391	2.1529	0.2366	2.0446	241.9055	118.4465	192.3781
196	0.3423	-0.7638	0.4562	2.9893	-0.8448	0.9957	-0.2192	0.2834	-0.1204	-0.3069	-0.4187	-0.6296	0.4321	0.3811	0.5451	1.669	0.0538	-0.5908	1.4778	0.0175	1.6026	278.2646	25.9088	298.0395
197	0.712	-0.1767	0.153	0.7313	0.3374	0.3945	0.012	-0.2833	0.305	0.4086	-0.0025	-0.0773	0.0752	0.1131	-0.0064	1.026	-0.0511	-0.3743	0.8577	-0.0397	0.8244	247.8814	58.2387	293.1876
198	0.424	0.0536	0.1059	0.6458	0.1639	0.2611	0.0231	0.1827	-0.08	-0.1282	-0.0599	-0.2459	0.0036	0.0968	0.0361	0.3832	0.0313	0.0964	0.4983	0.0991	0.6455	244.3051	15.2241	210.7455
199	0.9507	-0.1997	1.254	0.5203	-0.3036	2.6477	0.0564	-0.5018	0.0165	0.385	0.2484	-0.2898	-0.3385	0.7625	-0.2379	1.0631	-0.2968	-0.1241	1.8421	0.2162	1.6848	291.2564	59.973	236.8448
200	1.9074	0.7925	-0.8366	2.0971	-1.2379	1.2256	0.0654	0.4747	0.1686	-0.2452	0.3465	0.1573	-0.2893	0.1375	-0.3554	1.7435	-0.3095	-0.1208	1.3885	0.2159	1.4564	272.7315	90.0806	187.5839
201	0.5651	-0.1457	-0.7548	0.5992	0.5214	1.1962	0.172	-0.0302	0.1611	-0.0437	0.0112	-0.2892	-0.4178	-0.1464	-0.1756	0.5347	-0.1168	-0.0384	0.5808	0.2261	1.022	255.8863	63.4536	239.4181
202	1.21	-0.7444	-0.2577	0.4891	0.2389	0.5445	-0.0297	0.0123	0.2467	0.2491	0.0751	-0.1046	-0.3602	-0.204	-0.0026	1.1716	-0.0206	0.1321	1.0705	0.3801	0.9598	249.781	83.9798	188.1375
203	-0.094	0.0148	0.0729	0.4651	-0.2349	0.2824	-0.0168	-0.056	0.0594	0.0541	0.0222	-0.0859	0.1572	-0.0316	-0.0067	0.5653	0.0705	0.0976	0.5319	0.1489	0.7491	249.4999	-40.2824	265.1813
204	0.4311	-0.1182	-0.0338	0.6003	0.0681	0.305	0.013	0.0157	0.0538	-0.0236	-0.0587	0.0784	-0.1728	0.0121	0.0351	0.4775	-0.0727	-0.0618	0.3625	0.0864	0.4748	208.9845	48.098	235.8334

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth seq-ID	Auth asym-ID
1	X-RAY DIFFRACTION	1	segid S0A	0
2	X-RAY DIFFRACTION	2	segid S1A	0
3	X-RAY DIFFRACTION	3	segid S2A	0
4	X-RAY DIFFRACTION	4	segid S3A	0
5	X-RAY DIFFRACTION	5	segid S4A	0
6	X-RAY DIFFRACTION	6	segid S5A	0
7	X-RAY DIFFRACTION	7	segid S6A	0
8	X-RAY DIFFRACTION	8	segid S7A	0
9	X-RAY DIFFRACTION	9	segid S8A	0
10	X-RAY DIFFRACTION	10	segid S9A	0
11	X-RAY DIFFRACTION	11	segid S10A	1 - 96	0
12	X-RAY DIFFRACTION	12	segid S11A	2 - 156	1
13	X-RAY DIFFRACTION	13	segid S12A	20 - 143	2
14	X-RAY DIFFRACTION	14	segid S13A	2 - 151	3
15	X-RAY DIFFRACTION	15	segid S14A	11 - 137	4
16	X-RAY DIFFRACTION	16	segid S15A	8 - 131	5
17	X-RAY DIFFRACTION	17	segid S16A	3 - 143	6
18	X-RAY DIFFRACTION	18	segid S17A	2 - 126	7
19	X-RAY DIFFRACTION	19	segid S18A	2 - 146	8
20	X-RAY DIFFRACTION	20	segid S19A	2 - 144	9
21	X-RAY DIFFRACTION	21	segid S20A	15 - 121	0
22	X-RAY DIFFRACTION	22	segid S21A	1 - 87	1
23	X-RAY DIFFRACTION	23	segid S22A	2 - 130	2
24	X-RAY DIFFRACTION	24	segid S23A	2 - 145	3
25	X-RAY DIFFRACTION	25	segid S24A	2 - 135	4
26	X-RAY DIFFRACTION	26	segid S25A	36 - 105	5
27	X-RAY DIFFRACTION	27	segid S26A	2 - 500	6
28	X-RAY DIFFRACTION	28	segid S27A	2 - 101	7
29	X-RAY DIFFRACTION	29	segid S28A	5 - 67	8
30	X-RAY DIFFRACTION	30	segid S29A	4 - 99	9
31	X-RAY DIFFRACTION	31	segid S30A	2 - 61	0
32	X-RAY DIFFRACTION	32	segid S31A	82 - 501	1
33	X-RAY DIFFRACTION	33	segid SRKA	2 - 319	R
34	X-RAY DIFFRACTION	34	segid STMA	9 - 176	M
35	X-RAY DIFFRACTION	35	segid L2A	0
36	X-RAY DIFFRACTION	36	segid L3A	0
37	X-RAY DIFFRACTION	37	segid L4A	0
38	X-RAY DIFFRACTION	38	segid L5A	0
39	X-RAY DIFFRACTION	39	segid L6A	0
40	X-RAY DIFFRACTION	40	segid L7A	0
41	X-RAY DIFFRACTION	41	segid L8A	0
42	X-RAY DIFFRACTION	42	segid L9A	0
43	X-RAY DIFFRACTION	43	segid L10A	2 - 221	0
44	X-RAY DIFFRACTION	44	segid L11A	6 - 174	1
45	X-RAY DIFFRACTION	45	segid L13A	2 - 194	3
46	X-RAY DIFFRACTION	46	segid L14A	3 - 138	4
47	X-RAY DIFFRACTION	47	segid L15A	2 - 204	5
48	X-RAY DIFFRACTION	48	segid L16A	3 - 199	6
49	X-RAY DIFFRACTION	49	segid L17A	2 - 184	7
50	X-RAY DIFFRACTION	50	segid L18A	2 - 186	8
51	X-RAY DIFFRACTION	51	segid L19A and resid 2:73	2 - 73	9
52	X-RAY DIFFRACTION	52	segid L19A and resid 74:126	74 - 126	9
53	X-RAY DIFFRACTION	53	segid L19A and resid 127:183	127 - 183	9
54	X-RAY DIFFRACTION	54	segid L20A	1 - 172	0
55	X-RAY DIFFRACTION	55	segid L21A	2 - 160	1
56	X-RAY DIFFRACTION	56	segid L22A	9 - 108	2
57	X-RAY DIFFRACTION	57	segid L23A	2 - 137	3
58	X-RAY DIFFRACTION	58	segid L24A	1 - 98	4
59	X-RAY DIFFRACTION	59	segid L25A	22 - 142	5
60	X-RAY DIFFRACTION	60	segid L26A	2 - 127	6
61	X-RAY DIFFRACTION	61	segid L27A	2 - 136	7
62	X-RAY DIFFRACTION	62	segid L28A	2 - 149	8
63	X-RAY DIFFRACTION	63	segid L29A	2 - 59	9
64	X-RAY DIFFRACTION	64	segid L30A	9 - 105	0
65	X-RAY DIFFRACTION	65	segid L31A	4 - 112	1
66	X-RAY DIFFRACTION	66	segid L32A	2 - 128	2
67	X-RAY DIFFRACTION	67	segid L33A	2 - 107	3
68	X-RAY DIFFRACTION	68	segid L34A	2 - 113	4
69	X-RAY DIFFRACTION	69	segid L35A	2 - 120	5
70	X-RAY DIFFRACTION	70	segid L36A	2 - 100	6
71	X-RAY DIFFRACTION	71	segid L37A	2 - 100	7
72	X-RAY DIFFRACTION	72	segid L38A	2 - 78	8
73	X-RAY DIFFRACTION	73	segid L39A	2 - 51	9
74	X-RAY DIFFRACTION	74	segid L40A	77 - 500	0
75	X-RAY DIFFRACTION	75	segid L41A	1 - 25	1
76	X-RAY DIFFRACTION	76	segid L42A	2 - 501	2
77	X-RAY DIFFRACTION	77	segid L43A	2 - 501	3
78	X-RAY DIFFRACTION	78	segid S0B	0
79	X-RAY DIFFRACTION	79	segid S1B	0
80	X-RAY DIFFRACTION	80	segid S2B	0
81	X-RAY DIFFRACTION	81	segid S3B	0
82	X-RAY DIFFRACTION	82	segid S4B	0
83	X-RAY DIFFRACTION	83	segid S5B	0
84	X-RAY DIFFRACTION	84	segid S6B	0
85	X-RAY DIFFRACTION	85	segid S7B	0
86	X-RAY DIFFRACTION	86	segid S8B	0
87	X-RAY DIFFRACTION	87	segid S9B	0
88	X-RAY DIFFRACTION	88	segid S10B	1 - 98	0
89	X-RAY DIFFRACTION	89	segid S11B	2 - 147	1
90	X-RAY DIFFRACTION	90	segid S12B	20 - 143	2
91	X-RAY DIFFRACTION	91	segid S13B	2 - 151	3
92	X-RAY DIFFRACTION	92	segid S14B	10 - 137	4
93	X-RAY DIFFRACTION	93	segid S15B	4 - 138	5
94	X-RAY DIFFRACTION	94	segid S16B	2 - 143	6
95	X-RAY DIFFRACTION	95	segid S17B	2 - 122	7
96	X-RAY DIFFRACTION	96	segid S18B	2 - 146	8
97	X-RAY DIFFRACTION	97	segid S19B	2 - 144	9
98	X-RAY DIFFRACTION	98	segid S20B	12 - 121	0
99	X-RAY DIFFRACTION	99	segid S21B	1 - 87	1
100	X-RAY DIFFRACTION	100	segid S22B	2 - 130	2
101	X-RAY DIFFRACTION	101	segid S23B	2 - 145	3
102	X-RAY DIFFRACTION	102	segid S24B	2 - 135	4
103	X-RAY DIFFRACTION	103	segid S25B	37 - 105	5
104	X-RAY DIFFRACTION	104	segid S26B	2 - 500	6
105	X-RAY DIFFRACTION	105	segid S27B	2 - 1	7
106	X-RAY DIFFRACTION	106	segid S28B	5 - 67	8
107	X-RAY DIFFRACTION	107	segid S29B	4 - 99	9
108	X-RAY DIFFRACTION	108	segid S30B	2 - 63	0
109	X-RAY DIFFRACTION	109	segid S31B	77 - 501	1
110	X-RAY DIFFRACTION	110	segid SRKB	2 - 319	R
111	X-RAY DIFFRACTION	111	segid STMB	23 - 174	M
112	X-RAY DIFFRACTION	112	segid L2B	0
113	X-RAY DIFFRACTION	113	segid L3B	0
114	X-RAY DIFFRACTION	114	segid L4B	0
115	X-RAY DIFFRACTION	115	segid L5B	0
116	X-RAY DIFFRACTION	116	segid L6B	0
117	X-RAY DIFFRACTION	117	segid L7B	0
118	X-RAY DIFFRACTION	118	segid L8B	0
119	X-RAY DIFFRACTION	119	segid L9B	0
120	X-RAY DIFFRACTION	120	segid L10B	2 - 221	0
121	X-RAY DIFFRACTION	121	segid L11B	6 - 174	1
122	X-RAY DIFFRACTION	122	segid L12B	9 - 163	2
123	X-RAY DIFFRACTION	123	segid L13B	2 - 195	3
124	X-RAY DIFFRACTION	124	segid L14B	2 - 138	4
125	X-RAY DIFFRACTION	125	segid L15B	2 - 204	5
126	X-RAY DIFFRACTION	126	segid L16B	3 - 199	6
127	X-RAY DIFFRACTION	127	segid L17B	2 - 156	7
128	X-RAY DIFFRACTION	128	segid L18B	2 - 186	8
129	X-RAY DIFFRACTION	129	segid L19B and resid 2:73	2 - 73	9
130	X-RAY DIFFRACTION	130	segid L19B and resid 74:126	74 - 126	9
131	X-RAY DIFFRACTION	131	segid L19B and resid 127:183	127 - 183	9
132	X-RAY DIFFRACTION	132	segid L20B	1 - 172	0
133	X-RAY DIFFRACTION	133	segid L21B	2 - 160	1
134	X-RAY DIFFRACTION	134	segid L22B	11 - 108	2
135	X-RAY DIFFRACTION	135	segid L23B	2 - 137	3
136	X-RAY DIFFRACTION	136	segid L24B	1 - 135	4
137	X-RAY DIFFRACTION	137	segid L25B	23 - 142	5
138	X-RAY DIFFRACTION	138	segid L26B	2 - 127	6
139	X-RAY DIFFRACTION	139	segid L27B	2 - 136	7
140	X-RAY DIFFRACTION	140	segid L28B	2 - 149	8
141	X-RAY DIFFRACTION	141	segid L29B	2 - 59	9
142	X-RAY DIFFRACTION	142	segid L30B	6 - 105	0
143	X-RAY DIFFRACTION	143	segid L31B	4 - 112	1
144	X-RAY DIFFRACTION	144	segid L32B	2 - 128	2
145	X-RAY DIFFRACTION	145	segid L33B	2 - 107	3
146	X-RAY DIFFRACTION	146	segid L34B	2 - 113	4
147	X-RAY DIFFRACTION	147	segid L35B	2 - 120	5
148	X-RAY DIFFRACTION	148	segid L36B	2 - 100	6
149	X-RAY DIFFRACTION	149	segid L37B	2 - 501	7
150	X-RAY DIFFRACTION	150	segid L38B	2 - 78	8
151	X-RAY DIFFRACTION	151	segid L39B	2 - 51	9
152	X-RAY DIFFRACTION	152	segid L40B	77 - 500	0
153	X-RAY DIFFRACTION	153	segid L41B	1 - 25	1
154	X-RAY DIFFRACTION	154	segid L42B	2 - 501	2
155	X-RAY DIFFRACTION	155	segid L43B	2 - 501	3
156	X-RAY DIFFRACTION	156	segid LP0B	3 - 221	0
157	X-RAY DIFFRACTION	157	segid LP1B	1 - 47	1
158	X-RAY DIFFRACTION	158	segid LP2B	1 - 46	2
159	X-RAY DIFFRACTION	159	(segid 25SA and (not resid 1011:1039) and (not resid 1219:1288) and (not resid 1552:1583) and (not resid 2250:2266) and (not resid 2455:2502) and (not resid 2532:2547) and (not resid 2563:2578) and (not resid 3341:3364))	0
160	X-RAY DIFFRACTION	160	(segid 25SA and resid 1011:1039)	1011 - 1039	1
161	X-RAY DIFFRACTION	161	(segid 25SA and resid 1219:1288)	1219 - 1288	1
162	X-RAY DIFFRACTION	162	(segid 25SA and resid 1552:1583)	1552 - 1583	1
163	X-RAY DIFFRACTION	163	(segid 25SA and resid 2250:2266)	2250 - 2266	1
164	X-RAY DIFFRACTION	164	(segid 25SA and resid 2532:2547)	2532 - 2547	1
165	X-RAY DIFFRACTION	165	(segid 25SA and resid 2563:2578)	2563 - 2578	1
166	X-RAY DIFFRACTION	166	(segid 25SA and resid 3341:3364)	3341 - 3364	1
167	X-RAY DIFFRACTION	167	segid 5SA	0
168	X-RAY DIFFRACTION	168	segid 58SA	1 - 158	4
169	X-RAY DIFFRACTION	169	((segid 18SA and resid 1:602) and (not resid 64:86) and (not resid 185:200) and (not resid 219:237) and (not resid 480:509) and (not resid 510:545))	0
170	X-RAY DIFFRACTION	170	(segid 18SA and resid 64:86)	64 - 86	2
171	X-RAY DIFFRACTION	171	(segid 18SA and resid 185:200)	185 - 200	2
172	X-RAY DIFFRACTION	172	(segid 18SA and resid 219:237)	219 - 237	2
173	X-RAY DIFFRACTION	173	(segid 18SA and resid 480:509)	480 - 509	2
174	X-RAY DIFFRACTION	174	(segid 18SA and resid 510:545)	510 - 545	2
175	X-RAY DIFFRACTION	175	((segid 18SA and resid 603:1106) and (not resid 640:694) and (not resid 698:742) and (not resid 743:765) and (not resid 810:855))	0
176	X-RAY DIFFRACTION	176	(segid 18SA and resid 640:694)	640 - 694	2
177	X-RAY DIFFRACTION	177	(segid 18SA and resid 698:742)	698 - 742	2
178	X-RAY DIFFRACTION	178	(segid 18SA and resid 743:765)	743 - 765	2
179	X-RAY DIFFRACTION	179	(segid 18SA and resid 810:855)	810 - 855	2
180	X-RAY DIFFRACTION	180	(segid 18SA and resid 1107:1635)	1107 - 1635	2
181	X-RAY DIFFRACTION	181	(segid 18SA and resid 1636:1799)	1636 - 1799	2
182	X-RAY DIFFRACTION	182	(segid 25SB and (not resid 1011:1039) and (not resid 1219:1288) and (not resid 1552:1583) and (not resid 2250:2266) and (not resid 2455:2502) and (not resid 2532:2547) and (not resid 2563:2578) and (not resid 3341:3364))	0
183	X-RAY DIFFRACTION	183	(segid 25SB and resid 1011:1039)	1011 - 1039	5
184	X-RAY DIFFRACTION	184	(segid 25SB and resid 1219:1288)	1219 - 1288	5
185	X-RAY DIFFRACTION	185	(segid 25SB and resid 1552:1583)	1552 - 1583	5
186	X-RAY DIFFRACTION	186	(segid 25SB and resid 2250:2266)	2250 - 2266	5
187	X-RAY DIFFRACTION	187	(segid 25SB and resid 2532:2547)	2532 - 2547	5
188	X-RAY DIFFRACTION	188	(segid 25SB and resid 2563:2578)	2563 - 2578	5
189	X-RAY DIFFRACTION	189	(segid 25SB and resid 3341:3364)	3341 - 3364	5
190	X-RAY DIFFRACTION	190	segid 5SB	0
191	X-RAY DIFFRACTION	191	segid 58SB	1 - 158	8
192	X-RAY DIFFRACTION	192	((segid 18SB and resid 1:602) and (not resid 64:86) and (not resid 185:200) and (not resid 219:237) and (not resid 480:509) and (not resid 510:545))	0
193	X-RAY DIFFRACTION	193	(segid 18SB and resid 64:86)	64 - 86	6
194	X-RAY DIFFRACTION	194	(segid 18SB and resid 185:200)	185 - 200	6
195	X-RAY DIFFRACTION	195	(segid 18SB and resid 219:237)	219 - 237	6
196	X-RAY DIFFRACTION	196	(segid 18SB and resid 480:509)	480 - 509	6
197	X-RAY DIFFRACTION	197	(segid 18SB and resid 510:545)	510 - 545	6
198	X-RAY DIFFRACTION	198	((segid 18SB and resid 603:1106) and (not resid 640:694) and (not resid 698:742) and (not resid 743:765) and (not resid 810:855))	0
199	X-RAY DIFFRACTION	199	(segid 18SB and resid 640:694)	640 - 694	6
200	X-RAY DIFFRACTION	200	(segid 18SB and resid 698:742)	698 - 742	6
201	X-RAY DIFFRACTION	201	(segid 18SB and resid 743:765)	743 - 765	6
202	X-RAY DIFFRACTION	202	(segid 18SB and resid 810:855)	810 - 855	6
203	X-RAY DIFFRACTION	203	(segid 18SB and resid 1107:1635)	1107 - 1635	6
204	X-RAY DIFFRACTION	204	(segid 18SB and resid 1636:1799)	1636 - 1799	6