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- PDB-5on6: Crystal structure of haemanthamine bound to the 80S ribosome -

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Basic information

Entry
Database: PDB / ID: 5on6
TitleCrystal structure of haemanthamine bound to the 80S ribosome
Components
  • (40S ribosomal protein ...) x 31
  • (60S ribosomal protein ...) x 41
  • (Suppressor protein ...) x 2
  • (Ubiquitin-40S ribosomal protein ...) x 2
  • 18S ribosomal RNA
  • 25S ribosomal RNA
  • 5.8S ribosomal RNA
  • 5S ribosomal RNA
  • 60S acidic ribosomal protein P0
  • Guanine nucleotide-binding protein subunit beta-like protein
  • Ubiquitin-60S ribosomal protein L40
KeywordsRIBOSOME / Inhibitor / Cancer
Function / homology
Function and homology information


triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / regulation of amino acid metabolic process / negative regulation of glucose mediated signaling pathway / positive regulation of translational fidelity / Negative regulators of DDX58/IFIH1 signaling ...triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / regulation of amino acid metabolic process / negative regulation of glucose mediated signaling pathway / positive regulation of translational fidelity / Negative regulators of DDX58/IFIH1 signaling / RMTs methylate histone arginines / Protein methylation / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / pre-mRNA 5'-splice site binding / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / nonfunctional rRNA decay / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / response to cycloheximide / Ribosomal scanning and start codon recognition / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / preribosome, small subunit precursor / telomeric DNA binding / mRNA destabilization / Major pathway of rRNA processing in the nucleolus and cytosol / negative regulation of translational frameshifting / SRP-dependent cotranslational protein targeting to membrane / TOR signaling / GTP hydrolysis and joining of the 60S ribosomal subunit / negative regulation of mRNA splicing, via spliceosome / preribosome, large subunit precursor / positive regulation of protein kinase activity / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Formation of a pool of free 40S subunits / L13a-mediated translational silencing of Ceruloplasmin expression / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / translational elongation / ribosomal large subunit export from nucleus / G-protein alpha-subunit binding / 90S preribosome / Ub-specific processing proteases / ribosomal subunit export from nucleus / regulation of translational fidelity / protein-RNA complex assembly / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / translational termination / maturation of LSU-rRNA / ribosomal small subunit export from nucleus / translation regulator activity / translation repressor activity / DNA-(apurinic or apyrimidinic site) endonuclease activity / rescue of stalled ribosome / telomere maintenance / cellular response to amino acid starvation / protein kinase C binding / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / ribosomal large subunit biogenesis / ribosome assembly / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / macroautophagy / small-subunit processome / translational initiation / maintenance of translational fidelity / modification-dependent protein catabolic process / protein tag activity / cytoplasmic stress granule / rRNA processing / ribosome biogenesis / ribosome binding / ribosomal small subunit biogenesis / ribosomal small subunit assembly / small ribosomal subunit / 5S rRNA binding / ribosomal large subunit assembly / small ribosomal subunit rRNA binding / large ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / cytosolic large ribosomal subunit / cytoplasmic translation / negative regulation of translation / rRNA binding / protein ubiquitination / structural constituent of ribosome / ribosome / translation / G protein-coupled receptor signaling pathway / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / negative regulation of apoptotic process / nucleolus / perinuclear region of cytoplasm / mitochondrion / DNA binding
Similarity search - Function
Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P ...Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / : / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / : / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein L29e / Ribosomal L29e protein family / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein S2, eukaryotic / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / S27a-like superfamily / Ribosomal L38e protein family / Ribosomal protein L10e, conserved site / 40S Ribosomal protein S10 / Ribosomal protein L10e signature. / Ribosomal protein L19, eukaryotic / : / Ribosomal protein L10e / Ribosomal protein L6e signature. / Ribosomal protein L13e / Ribosomal protein L13e / Plectin/S10, N-terminal / Ribosomal protein L24e, conserved site / Plectin/S10 domain / Ribosomal protein L24e signature. / Ribosomal protein L44e signature. / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / : / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S7e signature. / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein S30 / Ribosomal protein S30 / Ribosomal protein S17e, conserved site / Ribosomal protein S17e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein S27a / : / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L23/L25, N-terminal / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein L23, N-terminal domain / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L18/L18-A/B/e, conserved site / Ribosomal L40e family / Ribosomal protein L18e signature. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein L30e signature 1. / Ribosomal protein L36e signature. / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein S3Ae, conserved site / Ribosomal protein S3Ae signature. / Ribosomal protein 60S L18 and 50S L18e / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein L35Ae, conserved site / Ribosomal protein L35Ae signature. / Ribosomal_L40e / Ribosomal protein L40e
Similarity search - Domain/homology
Haemanthamine / osmium (III) hexammine / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A ...Haemanthamine / osmium (III) hexammine / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Large ribosomal subunit protein eL18A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Small ribosomal subunit protein eS32A / Small ribosomal subunit protein eS32B / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein eS17B / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein uS11B / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A
Similarity search - Component
Biological speciesSaccharomyces cerevisiae (brewer's yeast)
MethodX-RAY DIFFRACTION / SYNCHROTRON / Resolution: 3.10000240787 Å
AuthorsPellegrino, S. / Meyer, M. / Yusupova, G. / Yusupov, M.
Funding support France, 3items
OrganizationGrant numberCountry
French National Research AgencyANR-15-CE11-0021-01 France
FRMDBF20160635745 France
European Research Council294312
CitationJournal: Structure / Year: 2018
Title: The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Authors: Pellegrino, S. / Meyer, M. / Zorbas, C. / Bouchta, S.A. / Saraf, K. / Pelly, S.C. / Yusupova, G. / Evidente, A. / Mathieu, V. / Kornienko, A. / Lafontaine, D.L.J. / Yusupov, M.
History
DepositionAug 3, 2017Deposition site: PDBE / Processing site: PDBE
Revision 1.0Feb 28, 2018Provider: repository / Type: Initial release
Revision 1.1Mar 14, 2018Group: Database references / Category: citation
Item: _citation.journal_volume / _citation.page_first / _citation.page_last
Revision 1.2May 8, 2024Group: Data collection / Database references / Derived calculations
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_conn_type
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_auth_comp_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr2_label_atom_id / _pdbx_struct_conn_angle.ptnr2_label_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Assembly

Deposited unit
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: 60S ribosomal protein L11-B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
lR: 60S ribosomal protein L23-A
6: 18S ribosomal RNA
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-B
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: 60S ribosomal protein L11-B
m2: 60S ribosomal protein L12
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-B
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
sM: Suppressor protein STM1,Suppressor protein STM1
p0: 60S acidic ribosomal protein P0
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: 40S ribosomal protein S3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-A
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: 40S ribosomal protein S20
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: 40S ribosomal protein S26-B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: 40S ribosomal protein S29-A
f: 40S ribosomal protein S30-A
g: Ubiquitin-40S ribosomal protein S31
h: Guanine nucleotide-binding protein subunit beta-like protein
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: 40S ribosomal protein S3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: 40S ribosomal protein S20
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: 40S ribosomal protein S26-B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: 40S ribosomal protein S29-A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin-40S ribosomal protein S31
sR: Guanine nucleotide-binding protein subunit beta-like protein
hetero molecules


Theoretical massNumber of molelcules
Total (without water)6,484,5232708
Polymers6,142,211160
Non-polymers342,3122548
Water00
1
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: 60S ribosomal protein L11-B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
lR: 60S ribosomal protein L23-A
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-B
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: 40S ribosomal protein S3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-A
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: 40S ribosomal protein S20
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: 40S ribosomal protein S26-B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: 40S ribosomal protein S29-A
f: 40S ribosomal protein S30-A
g: Ubiquitin-40S ribosomal protein S31
h: Guanine nucleotide-binding protein subunit beta-like protein
hetero molecules


Theoretical massNumber of molelcules
Total (without water)3,224,4871308
Polymers3,058,91379
Non-polymers165,5731229
Water0
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
2
6: 18S ribosomal RNA
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: 60S ribosomal protein L11-B
m2: 60S ribosomal protein L12
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-B
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
sM: Suppressor protein STM1,Suppressor protein STM1
p0: 60S acidic ribosomal protein P0
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: 40S ribosomal protein S3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: 40S ribosomal protein S20
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: 40S ribosomal protein S26-B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: 40S ribosomal protein S29-A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin-40S ribosomal protein S31
sR: Guanine nucleotide-binding protein subunit beta-like protein
hetero molecules


Theoretical massNumber of molelcules
Total (without water)3,260,0361400
Polymers3,083,29881
Non-polymers176,7381319
Water0
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)303.130, 286.500, 435.660
Angle α, β, γ (deg.)90.000, 98.866, 90.000
Int Tables number4
Space group name H-MP1211
Space group name HallP2yb

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Components

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RNA chain , 4 types, 8 molecules 1AR3AS4AT6A

#1: RNA chain 25S ribosomal RNA


Mass: 1097493.875 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: REF: 831416132
#2: RNA chain 5S ribosomal RNA


Mass: 38951.105 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: GenBank: 1039024380
#3: RNA chain 5.8S ribosomal RNA


Mass: 50682.922 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: GenBank: 1214879358
#25: RNA chain 18S ribosomal RNA


Mass: 579761.938 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: REF: 831416132

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60S ribosomal protein ... , 41 types, 81 molecules jCDkCElCFmCGnCHoCIpCJqCKrCLsCMtCNuCOvCPwCQxCR...

#4: Protein 60S ribosomal protein L2-A / L5 / Large ribosomal subunit protein uL2-A / RP8 / YL6


Mass: 27217.289 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX45
#5: Protein 60S ribosomal protein L3 / Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin ...Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1


Mass: 43719.602 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P14126
#6: Protein 60S ribosomal protein L4-A / L2 / Large ribosomal subunit protein uL4-A / RP2 / YL2


Mass: 39027.926 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P10664
#7: Protein 60S ribosomal protein L5 / L1 / L1a / Large ribosomal subunit protein uL18 / Ribosomal 5S RNA-binding protein / YL3


Mass: 33633.633 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P26321
#8: Protein 60S ribosomal protein L6-A / L17 / Large ribosomal subunit protein eL6-A / RP18 / YL16


Mass: 19869.369 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q02326
#9: Protein 60S ribosomal protein L7-A / L6 / Large ribosomal subunit protein uL30-A / RP11 / YL8


Mass: 25240.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05737
#10: Protein 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Large ribosomal subunit protein eL8-A / Maintenance of killer protein 7 / RP6 / YL5


Mass: 25814.998 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P17076
#11: Protein 60S ribosomal protein L9-A / L8 / Large ribosomal subunit protein uL6-A / RP24 / YL11


Mass: 21605.061 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05738
#12: Protein 60S ribosomal protein L10 / L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI- ...L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein


Mass: 25279.271 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P41805
#13: Protein 60S ribosomal protein L11-B / L16 / Large ribosomal subunit protein uL5-B / RP39 / YL22


Mass: 19266.082 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q3E757
#14: Protein 60S ribosomal protein L13-A / Large ribosomal subunit protein eL13-A


Mass: 21885.234 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q12690
#15: Protein 60S ribosomal protein L14-A / Large ribosomal subunit protein eL14-A


Mass: 14976.794 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P36105
#16: Protein 60S ribosomal protein L15-A / L13 / Large ribosomal subunit protein eL15-A / RP15R / YL10 / YP18


Mass: 24351.162 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05748
#17: Protein 60S ribosomal protein L16-A / L13a / L21 / Large ribosomal subunit protein uL13-A / RP22 / YL15


Mass: 22028.951 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P26784
#18: Protein 60S ribosomal protein L17-A / L20A / Large ribosomal subunit protein uL22-A / YL17


Mass: 20458.322 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05740
#19: Protein 60S ribosomal protein L18-A / Large ribosomal subunit protein eL18-A / RP28


Mass: 20478.059 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX49
#20: Protein 60S ribosomal protein L19-A / L23 / Large ribosomal subunit protein eL19-A / RP15L / RP33 / YL14


Mass: 21631.121 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX82
#21: Protein 60S ribosomal protein L20-A / L18a / Large ribosomal subunit protein eL20-A


Mass: 20478.852 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX23
#22: Protein 60S ribosomal protein L21-A / Large ribosomal subunit protein eL21-A


Mass: 18148.066 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q02753
#23: Protein 60S ribosomal protein L22-A / L1c / Large ribosomal subunit protein eL22-A / RP4 / YL31


Mass: 11263.863 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05749
#24: Protein 60S ribosomal protein L23-A / L17a / Large ribosomal subunit protein uL14-A / YL32


Mass: 14362.755 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX41
#26: Protein 60S ribosomal protein L24-A / L30 / Large ribosomal subunit protein eL24-A / RP29 / YL21


Mass: 11369.424 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P04449
#27: Protein 60S ribosomal protein L25 / Large ribosomal subunit protein uL23 / RP16L / YL25 / YP42'


Mass: 13771.176 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P04456
#28: Protein 60S ribosomal protein L26-A / L33 / Large ribosomal subunit protein uL24-A / YL33


Mass: 14134.588 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05743
#29: Protein 60S ribosomal protein L27-A / Large ribosomal subunit protein eL27-A


Mass: 15437.166 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0C2H6
#30: Protein 60S ribosomal protein L28 / L27a / L29 / Large ribosomal subunit protein uL15 / RP44 / RP62 / YL24


Mass: 16630.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P02406
#31: Protein 60S ribosomal protein L29 / Large ribosomal subunit protein eL29 / YL43


Mass: 6560.688 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05747
#32: Protein 60S ribosomal protein L30 / L32 / Large ribosomal subunit protein eL30 / RP73 / YL38


Mass: 10558.344 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P14120
#33: Protein 60S ribosomal protein L31-A / L34 / Large ribosomal subunit protein eL31-A / YL28


Mass: 12649.754 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0C2H8
#34: Protein 60S ribosomal protein L32 / Large ribosomal subunit protein eL32


Mass: 14478.054 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P38061
#35: Protein 60S ribosomal protein L33-A / L37 / Large ribosomal subunit protein eL33-A / RP47 / YL37


Mass: 12045.935 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05744
#36: Protein 60S ribosomal protein L34-A / Large ribosomal subunit protein eL34-A


Mass: 12608.831 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P87262
#37: Protein 60S ribosomal protein L35-A / Large ribosomal subunit protein uL29-A


Mass: 13811.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX84
#38: Protein 60S ribosomal protein L36-A / L39 / Large ribosomal subunit protein eL36-A / YL39


Mass: 11020.063 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05745
#39: Protein 60S ribosomal protein L37-A / L43 / Large ribosomal subunit protein eL37-A / YL35 / YP55


Mass: 9746.199 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P49166
#40: Protein 60S ribosomal protein L38 / Large ribosomal subunit protein eL38


Mass: 8714.363 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P49167
#41: Protein/peptide 60S ribosomal protein L39 / L46 / Large ribosomal subunit protein eL39 / YL40


Mass: 6227.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P04650
#43: Protein/peptide 60S ribosomal protein L41-B / L47 / Large ribosomal subunit protein eL41-B / YL41


Mass: 3354.243 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX87, UniProt: P0CX86*PLUS
#44: Protein 60S ribosomal protein L42-A / L41 / Large ribosomal subunit protein eL42-A / YL27 / YP44


Mass: 12115.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX27
#45: Protein 60S ribosomal protein L43-A / L37a / Large ribosomal subunit protein eL43-A / YL35


Mass: 9981.756 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX25
#47: Protein 60S ribosomal protein L12


Mass: 12783.750 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)

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Protein , 3 types, 5 molecules ANDOp0hsR

#42: Protein Ubiquitin-60S ribosomal protein L40


Mass: 6032.321 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CH08
#49: Protein 60S acidic ribosomal protein P0 / A0 / L10e / Large ribosomal subunit protein uL10


Mass: 33617.930 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05317
#82: Protein Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ...Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ribosomal subunit protein RACK1


Mass: 34710.023 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P38011

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Suppressor protein ... , 2 types, 2 molecules isM

#46: Protein Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / ...3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1


Mass: 29916.814 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P39015
#48: Protein Suppressor protein STM1,Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / ...3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1


Mass: 10296.888 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P39015

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40S ribosomal protein ... , 31 types, 62 molecules Bs0Cs1Ds2Es3Fs4Gs5Hs6Is7Js8Ks9Lc0Mc1Nc2Oc3Pc4...

#50: Protein 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A / Small ribosomal subunit protein uS2-A


Mass: 22811.074 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P32905
#51: Protein 40S ribosomal protein S1-A / RP10A / Small ribosomal subunit protein eS1-A


Mass: 24498.365 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P33442
#52: Protein 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / Small ribosomal subunit protein uS5 / YS5


Mass: 23212.979 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P25443
#53: Protein 40S ribosomal protein S3 / RP13 / Small ribosomal subunit protein uS3 / YS3


Mass: 24702.791 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05750
#54: Protein 40S ribosomal protein S4-A / RP5 / S7 / Small ribosomal subunit protein eS4-A / YS6


Mass: 29338.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX35
#55: Protein 40S ribosomal protein S5 / RP14 / S2 / Small ribosomal subunit protein uS7 / YS8


Mass: 22908.338 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P26783
#56: Protein 40S ribosomal protein S6-A / RP9 / S10 / Small ribosomal subunit protein eS6-A / YS4


Mass: 25895.072 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX37
#57: Protein 40S ribosomal protein S7-A / RP30 / RP40 / Small ribosomal subunit protein eS7-A


Mass: 21158.648 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P26786
#58: Protein 40S ribosomal protein S8-A / RP19 / S14 / Small ribosomal subunit protein eS8-A / YS9


Mass: 22406.609 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX39
#59: Protein 40S ribosomal protein S9-A / RP21 / S13 / Small ribosomal subunit protein uS4-A / YP28 / YS11


Mass: 21210.662 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: O13516
#60: Protein 40S ribosomal protein S10-A / Small ribosomal subunit protein eS10-A


Mass: 12757.445 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q08745
#61: Protein 40S ribosomal protein S11-A / RP41 / S18 / Small ribosomal subunit protein uS17-A / YS12


Mass: 17654.738 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX47
#62: Protein 40S ribosomal protein S12 / Small ribosomal subunit protein eS12


Mass: 13327.331 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P48589
#63: Protein 40S ribosomal protein S13 / S27a / Small ribosomal subunit protein uS15 / YS15


Mass: 16928.748 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05756
#64: Protein 40S ribosomal protein S14-B / RP59B / Small ribosomal subunit protein uS11-B


Mass: 13560.528 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P39516
#65: Protein 40S ribosomal protein S15 / RIG protein / RP52 / S21 / Small ribosomal subunit protein uS19 / YS21


Mass: 15900.712 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q01855
#66: Protein 40S ribosomal protein S16-A / RP61R / Small ribosomal subunit protein uS9-A


Mass: 15746.292 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX51
#67: Protein 40S ribosomal protein S17-A / RP51A / Small ribosomal subunit protein eS17-A


Mass: 14268.545 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P02407, UniProt: P14127*PLUS
#68: Protein 40S ribosomal protein S18-A / Small ribosomal subunit protein uS13-A


Mass: 16940.443 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX55
#69: Protein 40S ribosomal protein S19-A / RP55A / S16a / Small ribosomal subunit protein eS19-A / YP45 / YS16A


Mass: 15810.930 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P07280
#70: Protein 40S ribosomal protein S20 / Small ribosomal subunit protein uS10


Mass: 12575.547 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P38701
#71: Protein 40S ribosomal protein S21-A / S26 / Small ribosomal subunit protein eS21-A / YS25


Mass: 9758.829 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0C0V8
#72: Protein 40S ribosomal protein S22-A / RP50 / S24 / Small ribosomal subunit protein uS8-A / YP58 / YS22


Mass: 14518.867 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0C0W1
#73: Protein 40S ribosomal protein S23-A / RP37 / S28 / Small ribosomal subunit protein uS12-A / YS14


Mass: 15942.699 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX29
#74: Protein 40S ribosomal protein S24-A / RP50 / Small ribosomal subunit protein eS24-A


Mass: 15231.650 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX31
#75: Protein 40S ribosomal protein S25-A / RP45 / S31 / Small ribosomal subunit protein eS25-A / YS23


Mass: 8001.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q3E792
#76: Protein 40S ribosomal protein S26-B / Small ribosomal subunit protein eS26-B


Mass: 11022.989 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P39939
#77: Protein 40S ribosomal protein S27-A / RP61 / Small ribosomal subunit protein eS27-A / YS20


Mass: 8762.195 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P35997
#78: Protein 40S ribosomal protein S28-A / S33 / Small ribosomal subunit protein eS28-A / YS27


Mass: 7116.281 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: Q3E7X9
#79: Protein 40S ribosomal protein S29-A / S36 / Small ribosomal subunit protein uS14-A / YS29


Mass: 6335.303 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P41057
#80: Protein 40S ribosomal protein S30-A / Small ribosomal subunit protein eS30-A


Mass: 7006.346 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P0CX33

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Ubiquitin-40S ribosomal protein ... , 2 types, 2 molecules ge1

#81: Protein Ubiquitin-40S ribosomal protein S31


Mass: 8101.675 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05759
#83: Protein Ubiquitin-40S ribosomal protein S31


Mass: 5704.610 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (yeast)
References: UniProt: P05759

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Non-polymers , 5 types, 2548 molecules

#84: Chemical...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide


Mass: 286.365 Da / Num. of mol.: 1064 / Source method: obtained synthetically / Formula: H12N6Os
#85: Chemical...
ChemComp-MG / MAGNESIUM ION


Mass: 24.305 Da / Num. of mol.: 1461 / Source method: obtained synthetically / Formula: Mg
#86: Chemical ChemComp-HN8 / Haemanthamine / Haemanthamin / Natalensin / 3-Epicrinamine


Mass: 301.337 Da / Num. of mol.: 2 / Source method: obtained synthetically / Formula: C17H19NO4
#87: Chemical
ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL


Mass: 92.094 Da / Num. of mol.: 5 / Source method: obtained synthetically / Formula: C3H8O3
#88: Chemical
ChemComp-ZN / ZINC ION


Mass: 65.409 Da / Num. of mol.: 16 / Source method: obtained synthetically / Formula: Zn

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 3.16 Å3/Da / Density % sol: 61.02 %
Crystal growTemperature: 277 K / Method: vapor diffusion, hanging drop / pH: 7
Details: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

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Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: SOLEIL / Beamline: PROXIMA 1 / Wavelength: 1.148 Å
DetectorType: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Jan 20, 2016
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 1.148 Å / Relative weight: 1
ReflectionResolution: 3.1→100 Å / Num. obs: 1317777 / % possible obs: 99.5 % / Redundancy: 7.48 % / Biso Wilson estimate: 67.2869062598 Å2 / Rrim(I) all: 0.304 / Net I/σ(I): 9.74
Reflection shell

Diffraction-ID: 1

Resolution (Å)Redundancy (%)Rmerge(I) obsMean I/σ(I) obsNum. unique obsCC1/2Rrim(I) all% possible all
3.1-3.26.4582.0591.361188380.5172.23499
3.2-3.36.3971.4551.861052090.631.5899.2
3.3-3.46.3171.1052.43931350.7061.20299.3
3.4-3.56.5410.8653.16830300.7870.93799.5
3.5-3.66.4810.6933.93740760.8420.75299.5
3.6-3.756.2780.5414.94965360.8880.58999.2
3.75-46.4010.3636.931308380.9420.39499.5
4-56.4140.1911.472994600.9810.20799.6
5-66.5140.11116.731326080.9910.12199.5
6-814.2070.39620.241060410.9880.411100
8-1013.980.18627.08378490.9960.193100
10-2013.660.09934.58350230.9980.103100
20-3013.7070.04750.6336040.9990.049100
30-4013.0660.04761.728810.9990.04999.8
40-5011.620.05563.63260.9990.058100
50-759.3620.04558.212320.9980.04896.3
75-1006.0360.03945.12550.9990.04288.7
99.836-1002.750.03610.31360.9990.04175

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Processing

Software
NameVersionClassification
PHENIXdev_2450refinement
XSCALEdata scaling
XDSdata reduction
PHENIXphasing
RefinementResolution: 3.10000240787→99.8360192825 Å / SU ML: 0.42485159433 / Cross valid method: FREE R-VALUE / σ(F): 1.3453222355 / Phase error: 25.8770924525
Stereochemistry target values: GeoStd + Monomer Library + CDL v1.2
RfactorNum. reflection% reflection
Rfree0.252006497329 26196 1.98825837644 %
Rwork0.221759672393 1291339 -
obs0.222362191325 1317535 99.4564199961 %
Solvent computationShrinkage radii: 0.8 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL
Displacement parametersBiso mean: 72.5330409972 Å2
Refinement stepCycle: LAST / Resolution: 3.10000240787→99.8360192825 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms178888 222512 8993 0 410393
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.00562734859114437386
X-RAY DIFFRACTIONf_angle_d0.934912120925648733
X-RAY DIFFRACTIONf_chiral_restr0.045380452720779379
X-RAY DIFFRACTIONf_plane_restr0.0055069153758441681
X-RAY DIFFRACTIONf_dihedral_angle_d17.7039013546237047
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
3.1-3.13520.4101298108718470.38382121005642722X-RAY DIFFRACTION98.8766339869
3.1352-3.17210.3900226749198700.35582741616942684X-RAY DIFFRACTION99.0403856649
3.1721-3.21080.3770134697688680.33294471593142874X-RAY DIFFRACTION99.1679702555
3.2108-3.25150.3212169862028530.3123851651142885X-RAY DIFFRACTION99.1948835416
3.2515-3.29420.3309662466128740.3030922256342810X-RAY DIFFRACTION99.2051596494
3.2942-3.33940.3375008552238770.29886457023342875X-RAY DIFFRACTION99.2288850585
3.3394-3.38710.3274402831218740.28655817487442841X-RAY DIFFRACTION99.311645236
3.3871-3.43760.308732788798440.28081669044342893X-RAY DIFFRACTION99.4158294313
3.4376-3.49140.3045504716468810.27801048025143066X-RAY DIFFRACTION99.4636067355
3.4914-3.54860.3143028799648440.26829446360542885X-RAY DIFFRACTION99.5039479373
3.5486-3.60980.2754553513018800.24501809926142996X-RAY DIFFRACTION99.4402012556
3.6098-3.67540.255412184159300.23610002662342904X-RAY DIFFRACTION99.3923178087
3.6754-3.74610.2610938481159000.22181970373642694X-RAY DIFFRACTION98.9378602878
3.7461-3.82260.2545542022278660.21662074896342874X-RAY DIFFRACTION99.2602006082
3.8226-3.90570.248350192728970.2110469445942960X-RAY DIFFRACTION99.5279700443
3.9057-3.99660.2389919763368670.20529758084843135X-RAY DIFFRACTION99.5745643811
3.9966-4.09650.239944281918470.20217427436443054X-RAY DIFFRACTION99.5036264733
4.0965-4.20730.2472689848539150.20083717015543086X-RAY DIFFRACTION99.5700481999
4.2073-4.33110.2285046535788170.18825876679743064X-RAY DIFFRACTION99.6570675872
4.3311-4.47090.2242383902558880.18615205972843162X-RAY DIFFRACTION99.6944664479
4.4709-4.63070.2230251819828250.18728310561843192X-RAY DIFFRACTION99.6897223355
4.6307-4.81610.207963627748940.17962508230542966X-RAY DIFFRACTION99.4512720512
4.8161-5.03530.220398186168640.18176522125743069X-RAY DIFFRACTION99.4026743897
5.0353-5.30070.2076127765598640.18105343730843135X-RAY DIFFRACTION99.5903123585
5.3007-5.63280.2182182277648850.1852465814543179X-RAY DIFFRACTION99.5369219996
5.6328-6.06770.2105591921918730.18787089507443145X-RAY DIFFRACTION99.502689995
6.0677-6.67820.227075477898910.20020868051943350X-RAY DIFFRACTION99.9796610169
6.6782-7.64420.2311272376678850.20455927613543435X-RAY DIFFRACTION99.9887196842
7.6442-9.62960.2468319411848720.21704254995243598X-RAY DIFFRACTION100
9.6296-99.88780.2278683475529040.22855389983443806X-RAY DIFFRACTION99.5746197189
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.2193364292480.0238620613355-0.04131741607250.1781707983930.007730629717770.247022988558-0.000150325465469-0.000181524672597-0.0294308529074-0.00354252855604-0.0414455609608-0.06010405204450.004187667822630.06615453731180.03600491561550.367292332725-0.0169148838126-0.001980153896380.3542003385070.0644730706730.30216202792568.2830280065-1.3081460266747.9179580725
20.2553449844560.03909883744860.1640757054190.874238263914-0.3740372031470.430956738516-0.04150749915150.08129670062570.270797183533-0.1501187518710.09848479122180.40502247837-0.226912929429-0.192685217769-0.05594897478730.6967511457910.197689544688-0.05230878644060.5913698049240.1255207721710.65558026244712.924771407867.61473061526.2605517088
30.5660301954630.1509894868860.001768414958910.2769169755750.04809707574740.3600683260430.0168940188892-0.215888351242-0.1472297186140.107294584045-0.042204892818-0.2260775253860.08659449543950.3245562749810.03075168562330.4625734831890.00991386312057-0.08395730225620.7012286892810.1487460553150.533893846295114.929682687-7.2452523721982.4276352226
40.8482078692780.124581291318-0.346541365440.4980560118520.02693696412850.260027536525-0.02006033612070.07353207790010.0126728326658-0.14605160464-0.0456128492346-0.246817946873-0.07950353055460.1924668140190.06258070226360.463452412034-0.001428551988840.07997725978430.5874858694540.1189070326140.454475414328123.2158210014.3359817268816.5706329164
50.4705768056450.0783310732618-0.03577321138080.5773108122890.08408073213070.395981629096-0.0361315219560.0462162096555-0.3149978567310.0224651457953-0.06257925708040.04547593107560.304694181962-0.1149348811780.09478170489260.536882516659-0.09516061630530.07583003260860.372936603398-0.04099377406810.51898712614633.1299749181-60.569917677137.584221164
60.4046320778330.00291402013787-0.08385932061120.1925237625050.02388581483980.2625512110810.0501937908658-0.2248228786550.07354328351430.185229215826-0.0461619446469-0.0323102396294-0.08759470743410.0572767590957-0.004726262570880.534348794333-0.1003217460090.01188164996730.4819904092580.02237074001920.30645551322858.068590249725.1422396518102.916944883
70.416492901884-0.123748145884-0.02111503691750.90530565749-0.1680687860880.360907159892-0.1702440642130.05446844669620.523460659037-0.0438679161935-0.02628045927390.104319947602-0.397950409045-0.1150620200350.1691737415470.9435189652540.208347280313-0.1386503174640.4689285517380.108278346940.79857939013526.226594452893.856678654728.9465607073
80.6104846468190.263024576010.110776102710.5756433832160.003815175291710.1744068386990.0349851081396-0.131959111938-0.03528583512060.187006556294-0.05677469806980.0391859233644-0.0587377077982-0.01367342225010.02173446205630.46866732864-0.09198796252010.1041764255130.573805813929-0.0323570538680.326616325504-4.21739166601-11.6283758318106.414056536
91.43411942331-0.0821781009061-0.1754135665471.05107856516-0.08312992339860.757951428156-0.0247777943678-0.07690781532420.2621612348290.235411639322-0.01379579721410.17231271393-0.181238864743-0.177541590490.04759980481530.338596622670.0401584481360.03569772627390.322863054527-0.02452598432770.3260924322634.8754926212731.902012813777.4262234729
100.388895920755-0.22625015323-0.172811435970.9406915020530.3616061277010.5225861429840.0957322609542-0.05558612865090.0715134850943-0.04350854469690.00198449894824-0.427625066169-0.2161030634030.359776319338-0.1182095987070.545021074609-0.2747951133460.04983134266390.9824267825950.09855930953310.831030484663154.62688188540.123562779953.5283972257
110.63343657513-0.0766687870846-0.3864064097740.6847889949520.497983699960.973416315169-0.08237763760680.236355333101-0.24048005604-0.0204394199332-0.07812896749850.2060870915040.29284701907-0.3697584281780.1565441273230.592561433976-0.204577136953-0.004777557084480.744869837905-0.1216024853910.467563797575-11.9096554371-32.314597326618.6612727071
120.5637590030080.2723270949650.007579248336840.55584969850.08412842145270.8321419744470.09060163562340.1500200319380.0627020818294-0.239108405853-0.001248066209630.215242031365-0.0918529280451-0.238888930226-0.0788401300350.5562750161140.0325426463656-0.0743452539470.5767919936020.07416086230280.33828315197510.445659860327.832164232213.1968835959
130.523652290608-0.088230157309-0.04214304511540.524108962566-0.04468847931990.576378535241-0.02286997170380.4995666691820.250549400314-0.419906796158-0.07930074095130.0106568821627-0.35772781877-0.01104164895780.1092930471191.207128876790.074592633636-0.0790113979870.8337348539860.2436901569420.63625558415731.446286495579.4996411114-7.62237945951
140.9180551754980.1631326478650.1481523957870.8908844710390.1227398780480.2191043333940.0715748136775-0.1683884770590.2186980457710.143571044284-0.00119573789228-0.209876575-0.1722263529360.150447941999-0.06428928563970.555804825486-0.257921277919-0.03133737830610.605309161425-0.04379466622240.44877780988599.108088515855.397359603187.8726077892
150.4299226096040.1115854633580.1135892433410.226989173612-0.1770577086760.880502295792-0.0145795569729-0.03259147559130.005415859506530.033550840579-0.004428612054020.1261303126690.102478910764-0.344489327623-0.00208372205480.350955460376-0.07654285384750.06831904687790.5599880946670.0008976549431680.420349709352-26.2214789648-13.619198155465.0637421963
160.4904065826580.0433558359733-0.008457643173710.2684537424750.1037903846560.2765805731060.01825609197340.01517136497080.0792415236183-0.0549715495132-0.0088289475466-0.20571178039-0.1703212639130.225860018942-0.008488157109060.428240560734-0.173543971547-0.01140708576720.6510314859220.1187626237730.503161161001119.41799481632.4978791161.7353848555
170.0883737879191-0.120576728477-0.005066518034740.260457378870.07708122905030.435340646559-0.01628075996390.131539861582-0.05023443900180.03532620244720.001355359443240.104893349540.108984374839-0.1965373064280.03404761631560.396057250359-0.1288127583180.03698421616870.4732696681-0.07367810338830.3690782124623.3553840553-29.447793042457.0144715646
180.943624967668-0.3655380282360.4305965999880.853278439435-0.06878834320730.339464612655-0.080257736558-0.2831364739-0.1164604830760.164024646658-0.01165677864690.2280419508790.132782252331-0.0487088383650.07661259562290.463679874344-0.01300667603080.02386711732320.3843958874070.1111324366830.4314636671255.4220316749-39.95991075982.7935007915
190.4936244010880.0608923987827-0.03627977350510.4389653730050.05682276457560.5987214948370.085283972097-0.1561306338950.2089813374180.0662859586232-0.0690152792973-0.00985295281086-0.2389171018920.0478545198683-0.03773551745110.497306831756-0.07687561154960.03154551634510.361611635857-0.03139176339570.35073813265852.143666483350.281304295490.1264232282
200.4393973179560.0344922272316-0.101535467090.3102421331390.01078407499120.495445185108-0.07042791401110.216592183791-0.148628057173-0.146119334971-0.0288201905199-0.1938738017630.1598335348960.07375747487060.1325866410010.6237287018140.2409653365370.1242281656860.6635626571430.05066700085510.833523825886121.546160418-57.479972075310.6827556326
210.6801809443170.217447141717-0.2016914075490.561844882193-0.1689855440390.494063699209-0.1022056609290.1145889582220.115778196188-0.167070807420.06610056974020.078168851056-0.0301582467974-0.261408759290.0431609696450.3236804092940.0473688928355-0.01652621143380.558822674941-0.003610636026840.339423382404-12.326769314214.856788081447.3666215722
221.017514687150.4559985113740.09440390113340.499944469992-0.141935629620.147000731375-0.0253303715063-0.08110665323550.292237950890.0356057943747-6.74835380571E-50.213437930715-0.0858144042043-0.06581162206250.02987349094540.5363665943990.144734538096-0.02295329785680.409099217670.02288904344350.45240813742121.954236745855.557217056350.2416086576
230.942347218164-0.1877970605580.5134266014191.13613046430.1692501028950.4134090037640.0454303271018-0.0453186406498-0.5434051185950.0417136798699-0.0400204678992-0.04034636075110.2420161611820.1269682918490.002696249270411.07947975410.286830024619-0.00664707443010.7762786982120.05197703462711.33817982009113.270091475-89.327601172742.1793180078
240.3682676634290.11668431515-0.02934990363720.756850711898-0.03180203544330.473577927493-0.09531142127270.197229858713-0.135190033632-0.2274858127220.05631825987750.0557512606230.09715712629-0.1216697256150.04013385205050.4971535865560.02935644930550.06440507319460.495257535492-0.1260098740360.37908853174448.8808821066-44.8257415329-0.291363374934
250.26505798527-0.03604069010750.01720469244540.5001347633290.163731150840.2327288358640.0854158634397-0.115443212788-0.04279164100940.285111918134-0.06502198264490.001149375813210.109249708109-0.0251372519727-0.02702305779520.762141861341-0.1374581431190.05754978950070.5414017059130.04356337486230.403595283626201.666431594-25.1420024833274.745402494
260.4123041495530.2561939251410.3051319770410.8972324129170.6285687198060.6937410249020.1119192834930.502529252819-0.626512882228-0.1285863174510.0333454525504-0.06283335767540.843063520025-0.187242676016-0.1978491558461.03856007541-0.09044727676210.1073194712510.623104701401-0.1356258154060.92980964296556.9953518947-80.6236121313.64412405505
270.390975934535-0.1264883954160.1611294893520.3698196982630.1533648879260.39738247214-0.0110845003125-0.124380905211-0.1243694282940.0801067349876-0.0719759352553-0.3728421104140.07327717831480.2688674757260.07134125283530.4927539975870.148694879003-0.0695479039820.8046644637150.1982159749370.693469608218133.314109557-24.572442947374.1703961064
280.395592607891-0.175069203863-0.0268001148940.628575407622-0.06990093926970.50738400933-0.0737552522963-0.258810662897-0.1075544225220.3003904460450.170760602454-0.1184702936510.09825291254720.257408265988-0.08264662185610.62901894414-0.0914744345324-0.1518431662950.8732458448990.1647311131560.45160897764696.8705762186-11.322258398117.434847804
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1210.009908855367240.0505475017819-0.0307640999070.5352993745240.1279642196640.692979684799-0.006365737856950.281931998681-0.06185519792240.030635160899-0.0266095332378-0.333449613684-0.04818056653760.3501363854570.02612885633250.8081424381440.01054513799320.4018397671321.289107138810.1747874160770.994173504344152.027184691-16.7869736908-57.615953518
1220.726963797920.01438021028880.2467439233160.07331907796870.09820151085580.2071846148630.040018586872-0.121115193039-0.08518499557290.119997525410.0105955655673-0.344844519760.0411595796330.224131780344-0.03145861217751.085135324260.2780106429030.1079331171531.305354683560.3706375909091.66236803634117.8238292257.3519641284-58.4256587992
1230.231134292365-0.1993114950070.07082481431850.3377955199950.1303783208310.2723077652670.01018371145120.1578579637460.0509278105834-0.152206705801-0.0674056866343-0.01725167659790.0835449715352-0.05180229545680.05459207345631.063106830320.3117881429820.08137032258371.210538890480.2993563913180.60726422586148.825748173348.2887267523-72.9725676539
1240.711218037558-0.03500261981890.1834086319631.299203269040.906389549841.094523479210.05863572814220.3221228031120.117385669049-0.5227357147860.178291824120.000708999991834-0.1736727181080.179814706856-0.2301122519790.793519060290.2421595972330.02611310073351.152436616480.03151367788240.65311386895949.704617785-12.0901108985-73.7607391746
1250.365664758491-0.173850324361-0.1700846294380.512820212285-0.1492907170840.32408234292-0.01860587197070.059665010456-0.0451973761351-0.07986527375530.02471597219150.17161130035-0.0491752308522-0.24735759528-0.01877892301521.23075041460.1481594250370.04985048384891.655809077550.001974668448191.302655245212.563180856343.5806992591-60.5218579134
1260.393680715383-0.0762689191539-0.08083449732420.6082631446310.1544467748620.4434749536840.0658547511920.1503669263630.124106390056-0.2672263216330.0207076057639-0.314045333096-0.04193656322210.183761096093-0.0614569948611.334989656580.3777537028510.4141708798981.496799241480.587505527641.15857020376106.37449049658.2336984213-117.437016922
1270.9104867440970.0364819990971-0.09211657989530.2845388442570.007457880807670.360340811017-0.00568993153821-0.3867788037880.2618162428420.416300946144-0.0585362117150.2533454386270.0233578176446-0.1148007734660.03923686109531.5560793583-0.3084533128530.4685087428171.01829385687-0.2513891753130.823117318633169.3480858751.84267276876325.273782795
1280.6525330387250.0897673041132-0.201931764220.7871461098640.049901324240.545613063244-0.03798562400810.003480182614270.1978993756180.105111704269-0.059538849020.369921545613-0.148899425101-0.4091616100960.09027210470340.7850089019670.2211387850920.2249170873090.886319107855-0.1718087309970.861989100503137.47660885725.510279937263.534066788
1290.6962704431690.0338937642356-0.1186496127490.36188787866-0.05084087343830.9134165808450.0819221783413-0.3618076322580.08736063134060.424700834025-0.06949719850430.00665761597678-0.0210664851846-0.000532574705566-0.005975592184991.36829102634-0.2324799433640.0001717989926440.7373956062080.003537913706150.503562978207201.231466332-16.6750041425312.568447793
1301.42859884232-0.0471074424709-0.4301185053710.793776319999-0.2734783693390.833936764337-0.199103138403-0.4130225325-0.4100316021480.0944298970947-0.0507143163626-0.2141622638250.2677583197370.2991038617830.2537747096660.9995909496360.0518843469137-0.02422563637320.7562375564370.03052479200680.858821401649232.67212873923.2568095141313.720092382
1310.6846130003930.0294908784505-0.4078484530260.585671152208-0.1519763902890.5040174351680.0031371813739-0.29803386998-0.2336569574690.501086212539-0.06153226910010.1169052835550.351919252883-0.04657401019090.07002570389251.47945892094-0.129384493052-0.03282452439360.5810109622750.1655187347010.696065136709202.065122528-87.3440726579287.84363189
1321.17946552198-0.482891070755-0.2678847255420.388427531127-0.3276735663411.10852762020.03301008741930.2536063242970.3780328710860.00922847874030.153125094050.2329700541660.00961831049557-0.388961725436-0.1630558475340.891164336842-0.1531939179750.07433821245850.8740800763320.1353323556011.36647468891188.54520104970.1469407672287.936617658
1330.646217582486-0.0802770037464-0.1891861803380.7568902264240.09342666097710.8240438256110.09777043710680.0766609665831-0.2921611803950.203354542276-0.100575112581-0.2958251463580.3211714781550.01915057200720.03850551014370.9384368055950.0767237806895-0.1366337929180.423224921973-0.06917674935290.863232352898221.830981868-102.883004913234.687076249
1340.832963143958-0.0208672299248-0.08908512296980.53422841702-0.003222749863270.6865143575340.116460011637-0.351639609167-0.2813228814120.291909518518-0.109967996520.463374924390.203393386649-0.356944459182-0.01286697384461.35180594338-0.4634963306770.366229445241.239988085960.04209308434390.96488389498140.011400587-52.5422573002311.455651799
1350.411993927225-0.332330069536-0.08894728709550.70853911952-0.2505829133470.7729317924690.09471636354910.0574759312861-0.488532405078-0.00338398727107-0.07892677418450.3067061095750.368602235126-0.337052255564-0.003975071802960.910564088817-0.228844865713-0.04267244377110.56176005653-0.1116771708270.921085483467175.343747776-91.7960188664240.6385928
1360.493211287816-0.1512984229460.06824290648910.697184344035-0.07106337656540.684877359797-0.105785875228-0.339832135946-0.05961649021320.4873240555280.0879979624223-0.1810976107240.2038282251230.1400603760030.01933470378841.55390168426-0.0659779648056-0.2723314789480.774788904290.04232523982970.591829546055227.71505091-49.6468988497304.77896428
1370.480641250272-0.2890473085940.2158781742870.6603721620610.5233523348981.331133268580.172894297607-0.00313751982811-0.1792266576710.304546570143-0.1248371796520.5239025536440.286235444341-0.310714854545-0.05127195166850.911578778509-0.2671130810790.1785743479410.617551247759-0.006707118626310.837592936509168.451719976-71.1075297299262.880400344
1380.285202464105-0.3053641280620.09029945978890.3641859686940.04642900038840.5183709617420.05261284908560.1001726978310.04910696911330.1578474271870.0448941743005-0.0845006800380.06725412383560.0839276468415-0.08429205203931.586378401940.2422381403850.1412840385282.11481016870.2181761121842.13951436788297.67373775720.1282595444295.702637292
1390.4809867039720.146895296206-0.07555273872390.605994155928-0.03667821779440.07487473844190.00325662554345-0.264173480369-0.1043597926060.20547380192-0.07802315555810.3093109798610.171841300456-0.3513877831060.07644341341770.792610574009-0.2056549029510.2839815229550.913255337497-0.06205396123870.773109269609143.079805348-33.1046309094274.631212443
1400.268555884126-0.1910183457250.1026437486540.477566773269-0.05931200213070.113710396365-0.019336378013-0.08655165599460.338627118594-0.007112281049390.0154243668320.00466007373262-0.256556970968-0.1470782576870.001638956334831.075868556190.1563143941230.113988720170.753443149395-0.1109802054240.956760038467160.4751734937.3178266419260.646820367
1410.6162361222250.196632210819-0.5453950000791.04067355064-0.6321384387440.882579705793-0.1588351295020.2283790283660.0408217076177-0.136577605919-0.124586604753-0.2161321967360.2420076379970.0640672166250.2557233055741.08720716677-0.2805998037760.2612223177790.910811974258-0.1359112130421.07584155977257.68834652660.0690145128258.488350309
1421.05969841495-0.359766598225-0.5411472859260.770556336899-0.3020852295910.647672666320.0914219337079-0.2789299423460.5529928557580.2727461580930.195776261256-0.0424253511805-0.09853530077860.0587272302382-0.2669101201120.946607448896-0.07380115693110.172501106030.640586716155-0.2849692413011.17300234207205.8659675871.1329829849309.648266943
1430.1893790641070.180678019247-0.09914513695630.3059847106630.0278104855880.1541486302320.053138436735-0.2025129927570.0137380933290.284557912562-0.1837582775170.293040572347-0.047042943851-0.1590613085260.1292169390651.28593729883-0.1024844898040.2917860395861.04479012785-0.2417991092630.946537403134181.70496412325.7849948006326.378097522
1440.4432748324650.0241609386963-0.07985057375840.413732229555-0.03032230714070.53937109812-0.07258298015350.3534155075690.290969144231-0.2339773813560.07455068102860.04354565379660.0397986722602-0.26043795562-0.0008184906982280.991497534299-0.431492573190.03900311748511.021119156610.1409762010551.23122108712230.47752485281.1873358709260.282466453
1450.6840033158040.0928321850287-0.001428561873280.9927526980030.009536414515910.6737812897520.00321884087295-0.1815875279580.6526949547650.2097521863660.0768061946491-0.0250896115928-0.2889154258010.0510846238696-0.06801743041751.01574054141-0.2236566420.001949213961590.650907975133-0.2115270496481.24143450712227.63934097887.9376203418293.57040675
1460.642640125156-0.2785210563930.2897782741030.423719864485-0.2236088943460.1591018947680.0233975278368-0.00327205006529-0.06154436650560.0337759145536-0.125639931625-0.3625970989260.1692240519840.3762245760670.08595281603341.293808799090.3323555478670.1386454979941.345369783860.137079441351.41703610136264.72779909627.5313741699301.596831875
1471.31031484628-0.348309078301-0.2069715349421.20098906725-0.2967616229590.978167630769-0.295100167977-0.560857690010.1422638605880.355467145485-0.111845264642-0.387257637596-0.3199159346440.2768986590090.3920905459751.03427352115-0.0839326895042-0.1180606213271.02029929372-0.1021737332310.939264129316236.3386991650.4613291168321.052158246
1481.100649788010.01818948485620.04130708387310.290887194928-0.09491795802410.4106148883980.0594548198629-0.4558609490170.1237976488520.549530333378-0.05754511272610.1786437414870.0784824541147-0.0456695908271-0.01177972149591.45550560549-0.2089950632740.2815649304391.06498146323-0.06271574734910.568566708285176.896898197-18.5640601004323.845452467
1490.7325964989190.136543460814-0.0909975500290.284319442570.1547983097740.657960655386-0.0932308933866-0.314228867652-0.1446017853070.427906527599-0.02797580291730.1513277762320.286133557552-0.06064602011240.09311845116161.0911626883-0.2350458343510.2512687843760.7520644567430.01743318049080.495591740522174.649000474-38.5485793462301.992737039
1500.6103329620560.191442191436-0.1475964457410.4780411978390.009065299115770.4629751767040.0681578595849-0.001005900164530.06777848288890.205723317559-0.0219209257784-0.04901643576810.0452595910261-0.00322871562849-0.04367365231720.654468752448-0.105459801889-0.02563240418390.3951815752330.003110849790380.440897633171218.401747495-27.0901664763264.377237947
1510.5632120279510.01992791166670.4560724952220.683014922275-0.03629630861770.6271245008980.147800408277-0.180270678839-0.2121209994920.5519810117650.114590076551-0.2413135319460.4317736523680.337259811667-0.2022336900661.166645688340.112912640468-0.3728646692570.6049708764760.06772771731940.899514427192239.352625822-84.6459006513279.926206466
1520.6311085211560.0166386202160.07862969300540.392295114606-0.1678832360660.4240872478660.02918364471350.1407560116060.255043126207-0.148996912249-0.06385323782320.0168330683089-0.348584577236-0.09616734833380.02342984002611.18953442859-0.09220922742770.04008762635980.8218367617730.2630942005631.81729894426198.46499477994.2963962111274.056166541
1530.6158240671470.02726899956850.09888085316750.0159764120428-0.07381542138850.44634824533-0.0540171781336-0.1889793923240.2405621633090.3868362875280.1050530490590.0668416164051-0.319214738638-0.271679272422-0.05079341662220.9697719895230.04131171761560.2213916620570.669813587649-0.1679859801860.57870870888167.58544543818.9184988699276.127335505
1540.0287705131074-0.128163933816-0.04029012157230.799808407068-0.1425270386850.890383409893-0.000736326253421-0.27340378332-0.143959199030.147879146559-0.04581359142540.4087881275370.0384108689172-0.5358549584870.04083459549530.915282147136-0.08696242090460.4298052729951.02194483784-0.03262192520370.88767701969135.274976344-20.8978432452295.632769677
1550.633410452690.06534952779220.1962128269590.0510483254647-0.1057663701010.453514039031-0.0241352456479-0.0374386465383-0.128587828421-0.0407309310756-0.05580144249560.3159400367580.0176025797006-0.2967538454960.07536589267950.954176501538-0.2529400680650.1636884119641.28581824180.1127746035511.47585215571171.90253435650.2517739628288.576807235
1560.4544482789560.586837330283-0.3293553717960.772651011524-0.3628978381131.05469948218-0.0736805059832-0.0547267687787-0.135636805648-0.07538067353-0.0654613916657-0.05123584123880.1709099757050.2423934405080.1431535793480.8911255379220.01039727958210.05130077349860.70376619385-0.1325387267841.01525966853242.34506853540.514818645293.07132728
1570.529473260467-0.114857301383-0.1619416670840.799942516179-0.8812757768061.202058882610.0818422570372-0.3435613228670.1623316180070.3637888174950.0485500101572-0.0886541891008-0.1943457601050.135458582087-0.1166772011351.05336257733-0.195992421765-0.1998712395480.767307640186-0.01768335185540.796025472202239.057060232-20.2485884945289.860180044
1580.05175262150740.0787687343892-0.05268496783580.123918709662-0.05075413883220.153568753087-0.00260169374424-0.105162434192-0.06098220819330.068648355660.0375695425714-0.08798510648670.1202045583940.129161894299-0.02927784096051.415690207840.1474055669310.1263936722521.999409471730.1952737508811.90092410797294.53635540639.7761707183279.363469895
1590.5436249319080.128070643418-0.08693848622250.626230296161-0.005637033366430.772349130737-0.0257383976637-0.6316273463760.3613513509920.706098379850.02583173357310.1848354419180.000471647293643-0.22441103183-0.009949354546991.63116503652-0.07271492596330.3060528404271.43824904172-0.5117905567791.0912698201191.46609065753.4406528567344.397035094
1600.834491725850.721926373518-0.2755218476570.651989896663-0.3273158569071.706531690310.03964985173340.0494682070958-0.1368104242830.05748888407950.083906979056-0.2676658180140.2510916384850.350896046568-0.1041678149270.9912112244480.0149858968476-0.05346614403270.9885439974330.2157557742511.53746164813324.365627611-14.8559969522187.014097794
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection details
1X-RAY DIFFRACTION1chain 1
2X-RAY DIFFRACTION2chain 3
3X-RAY DIFFRACTION3chain 4
4X-RAY DIFFRACTION4chain j
5X-RAY DIFFRACTION5chain k
6X-RAY DIFFRACTION6chain l
7X-RAY DIFFRACTION7chain m
8X-RAY DIFFRACTION8chain n
9X-RAY DIFFRACTION9chain o
10X-RAY DIFFRACTION10chain p
11X-RAY DIFFRACTION11chain q
12X-RAY DIFFRACTION12chain r
13X-RAY DIFFRACTION13chain s
14X-RAY DIFFRACTION14chain t
15X-RAY DIFFRACTION15chain u
16X-RAY DIFFRACTION16chain v
17X-RAY DIFFRACTION17chain w
18X-RAY DIFFRACTION18chain x
19X-RAY DIFFRACTION19chain y
20X-RAY DIFFRACTION20chain z
21X-RAY DIFFRACTION21chain 0
22X-RAY DIFFRACTION22chain 2
23X-RAY DIFFRACTION23chain 5
24X-RAY DIFFRACTION24chain lR
25X-RAY DIFFRACTION25chain 6
26X-RAY DIFFRACTION26chain 7
27X-RAY DIFFRACTION27chain 8
28X-RAY DIFFRACTION28chain 9
29X-RAY DIFFRACTION29chain AA
30X-RAY DIFFRACTION30chain AB
31X-RAY DIFFRACTION31chain AC
32X-RAY DIFFRACTION32chain AD
33X-RAY DIFFRACTION33chain AE
34X-RAY DIFFRACTION34chain AF
35X-RAY DIFFRACTION35chain AG
36X-RAY DIFFRACTION36chain AH
37X-RAY DIFFRACTION37chain AI
38X-RAY DIFFRACTION38chain AJ
39X-RAY DIFFRACTION39chain AK
40X-RAY DIFFRACTION40chain AL
41X-RAY DIFFRACTION41chain AM
42X-RAY DIFFRACTION42chain AN
43X-RAY DIFFRACTION43chain AO
44X-RAY DIFFRACTION44chain AP
45X-RAY DIFFRACTION45chain AQ
46X-RAY DIFFRACTION46chain o1
47X-RAY DIFFRACTION47chain i
48X-RAY DIFFRACTION48chain AR
49X-RAY DIFFRACTION49chain AS
50X-RAY DIFFRACTION50chain AT
51X-RAY DIFFRACTION51chain CD
52X-RAY DIFFRACTION52chain CE
53X-RAY DIFFRACTION53chain CF
54X-RAY DIFFRACTION54chain CG
55X-RAY DIFFRACTION55chain CH
56X-RAY DIFFRACTION56chain CI
57X-RAY DIFFRACTION57chain CJ
58X-RAY DIFFRACTION58chain CK
59X-RAY DIFFRACTION59chain CL
60X-RAY DIFFRACTION60chain CM
61X-RAY DIFFRACTION61chain CN
62X-RAY DIFFRACTION62chain CO
63X-RAY DIFFRACTION63chain CP
64X-RAY DIFFRACTION64chain CQ
65X-RAY DIFFRACTION65chain CR
66X-RAY DIFFRACTION66chain CS
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