PDB-4u4o: Crystal structure of Geneticin bound to the yeast 80S ribosome

Basic information

• Entry: Database: PDB / ID: 4u4o
• Title: Crystal structure of Geneticin bound to the yeast 80S ribosome

Components

• (40S ribosomal protein ...) x 32
• (60S ribosomal protein ...) x 40
• (Ubiquitin-40S ribosomal protein ...) x 2
• (unknown protein chain ...) x 3
• 18S ribosomal RNA
• 25S ribosomal RNA
• 5.8S ribosomal RNA
• 5S ribosomal RNA
• 60S acidic ribosomal protein P0
• Guanine nucleotide-binding protein subunit beta-like protein
• Suppressor protein STM1
• Ubiquitin-60S ribosomal protein L40

• Keywords: RIBOSOME / translation / 40S / 60S / 80S / eukaryote / RNA-protein complex / inhibitor / antibiotic

Function / homology

Function:

triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / negative regulation of glucose mediated signaling pathway / negative regulation of translational frameshifting / Negative regulators of DDX58/IFIH1 signaling / RMTs methylate histone arginines / positive regulation of translational fidelity / Protein methylation / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / nonfunctional rRNA decay / hexon binding / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / pre-mRNA 5'-splice site binding / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / preribosome, small subunit precursor / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / Ribosomal scanning and start codon recognition / response to cycloheximide / telomeric DNA binding / Major pathway of rRNA processing in the nucleolus and cytosol / mRNA destabilization / SRP-dependent cotranslational protein targeting to membrane / GTP hydrolysis and joining of the 60S ribosomal subunit / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Formation of a pool of free 40S subunits / negative regulation of mRNA splicing, via spliceosome / preribosome, large subunit precursor / regulation of amino acid metabolic process / L13a-mediated translational silencing of Ceruloplasmin expression / translational elongation / ribosomal large subunit export from nucleus / 90S preribosome / G-protein alpha-subunit binding / positive regulation of protein kinase activity / TOR signaling / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / regulation of translational fidelity / Ub-specific processing proteases / protein-RNA complex assembly / ribosomal subunit export from nucleus / ribosomal small subunit export from nucleus / translation regulator activity / translational termination / translation repressor activity / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / DNA-(apurinic or apyrimidinic site) endonuclease activity / maturation of LSU-rRNA / telomere maintenance / cellular response to amino acid starvation / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rescue of stalled ribosome / ribosome assembly / ribosomal large subunit biogenesis / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / translational initiation / macroautophagy / protein kinase C binding / maintenance of translational fidelity / modification-dependent protein catabolic process / cytoplasmic stress granule / protein tag activity / rRNA processing / ribosomal small subunit biogenesis / small ribosomal subunit rRNA binding / ribosome biogenesis / viral capsid / ribosome binding / ribosomal small subunit assembly / small ribosomal subunit / 5S rRNA binding / large ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / ribosomal large subunit assembly / cytoplasmic translation / cytosolic large ribosomal subunit / negative regulation of translation / rRNA binding / ribosome / protein ubiquitination / structural constituent of ribosome / positive regulation of protein phosphorylation / G protein-coupled receptor signaling pathway / translation / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / negative regulation of apoptotic process / host cell nucleus

Domain/homology:

Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / Pre-hexon-linking protein VIII / Adenovirus hexon associated protein, protein VIII / 50S ribosomal protein L10, insertion domain superfamily / : / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal protein 60S L18 and 50S L18e / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S26e / Ribosomal protein S21e, conserved site / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S21e signature. / : / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / Small (40S) ribosomal subunit Asc1/RACK1 / S27a-like superfamily / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / 40S Ribosomal protein S10 / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L44e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L10e / Ribosomal protein L13e / Ribosomal protein S27a / Ribosomal protein L13e / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein L19, eukaryotic / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein S17e, conserved site / Ribosomal protein S17e signature. / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S30 / : / Ribosomal protein S30 / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein S7e signature. / : / Ribosomal protein L24e, conserved site / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L24e signature. / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / : / Ribosomal protein S19e / Ribosomal protein S3Ae, conserved site / Ribosomal protein S19e / Ribosomal protein L30e signature 1. / Ribosomal protein L6e signature. / Ribosomal protein S3Ae signature. / Ribosomal_S19e / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein S27e signature. / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal L40e family / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein S4e, N-terminal, conserved site / Ribosomal protein S4e signature.

Component:

GENETICIN / osmium (III) hexammine / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein uS11A / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Pre-hexon-linking protein VIII / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Small ribosomal subunit protein eS32A / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A

• Biological species: Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.6 Å
• Authors: Garreau de Loubresse, N. / Prokhorova, I. / Yusupova, G. / Yusupov, M.
• Citation: Journal: Nature / Year: 2014; Title: Structural basis for the inhibition of the eukaryotic ribosome.; Authors: Garreau de Loubresse, N. / Prokhorova, I. / Holtkamp, W. / Rodnina, M.V. / Yusupova, G. / Yusupov, M.

History

Deposition	Jul 24, 2014	Deposition site: RCSB / Processing site: PDBE
Revision 1.0	Oct 22, 2014	Provider: repository / Type: Initial release
Supersession	Dec 10, 2014	ID: 4ukz, 4ul0, 4ul1, 4ul2, 4ul3
Revision 1.1	Dec 10, 2014	Group: Other
Revision 1.2	Dec 17, 2014	Group: Other
Revision 1.3	Jan 14, 2015	Group: Database references
Revision 1.4	Jan 20, 2016	Group: Derived calculations / Structure summary
Revision 1.5	Dec 20, 2023	Group: Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_conn_type Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id

Assembly

Deposited unit

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m2: unknown protein chain m2

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

p1: unknown protein chain p1

p2: unknown protein chain p2

hetero molecules

Summary:

• 6.63 MDa, 162 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	6,630,740	2720
Polymers	6,271,048	162
Non-polymers	359,692	2558
Water	0	0

1

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

hetero molecules

Summary:

• defined by author
• 3.28 MDa, 79 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,284,533	1322
Polymers	3,107,816	79
Non-polymers	176,718	1243
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m2: unknown protein chain m2

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

p1: unknown protein chain p1

p2: unknown protein chain p2

hetero molecules

Summary:

• defined by author
• 3.35 MDa, 83 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,346,207	1398
Polymers	3,163,233	83
Non-polymers	182,974	1315
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	437.000, 286.750, 305.180
Angle α, β, γ (deg.)	90.000, 99.240, 90.000
Int Tables number	4
Space group name H-M	P1211

• Details: there are 2 biological units in the asymetric unit (segid *A and segid *B)

Components

RNA chain , 4 types, 8 molecules 2 6 1 5 3 7 4 8

#1: RNA chain

2 6 18S ribosomal RNA / RNA (1750-MER)

Details:

Mass: 579761.938 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 1262303

#36: RNA chain

1 5 25S ribosomal RNA / RNA (3149-MER)

Details:

Mass: 1097493.875 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#37: RNA chain

3 7 5S ribosomal RNA / RNA (121-MER)

Details:

Mass: 38951.105 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#38: RNA chain

4 8 5.8S ribosomal RNA

Details:

Mass: 50682.922 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 618731124

40S ribosomal protein ... , 32 types, 62 molecules S0 s0 S1 s1 S2 s2 S3 s3 S4 s4 S5 s5 S6 s6 S7 s7 S8 s8 S9 s9 C0 c0 C1 c1 C2 c2 C3 c3 C4 c4 ...

#2: Protein

S0 s0 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A

Details:

Mass: 27920.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P32905

#3: Protein

S1 s1 40S ribosomal protein S1-A / RP10A

Details:

Mass: 28667.275 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P33442

#4: Protein

S2 s2 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / YS5

Details:

Mass: 27359.629 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P25443

#5: Protein

S3 s3 40S ribosomal protein S3 / RP13 / YS3

Details:

Mass: 26411.596 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05750

#6: Protein

S4 s4 40S ribosomal protein S4-A / RP5 / S7 / YS6

Details:

Mass: 29338.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX35

#7: Protein

S5 s5 40S ribosomal protein S5 / RP14 / S2 / YS8

Details:

Mass: 24941.402 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26783

#8: Protein

S6 s6 40S ribosomal protein S6-A / RP9 / S10 / YS4

Details:

Mass: 27054.486 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX37

#9: Protein

S7 s7 40S ribosomal protein S7-A / RP30 / RP40

Details:

Mass: 21527.014 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26786

#10: Protein

S8 s8 40S ribosomal protein S8-A / RP19 / S14 / YS9

Details:

Mass: 22537.803 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX39

#11: Protein

S9 s9 40S ribosomal protein S9-A / RP21 / S13 / YP28 / YS11

Details:

Mass: 22356.695 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: O13516

#12: Protein

C0 c0 40S ribosomal protein S10-A

Details:

Mass: 12771.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q08745

#13: Protein

C1 c1 40S ribosomal protein S11-A / RP41 / S18 / YS12

Details:

Mass: 17668.766 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX47

#14: Protein

C2 c2 40S ribosomal protein S12

Details:

Mass: 15385.485 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P48589

#15: Protein

C3 c3 40S ribosomal protein S13 / S27a / YS15

Details:

Mass: 16928.748 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05756

#16: Protein

C4 c4 40S ribosomal protein S14-A / RP59A

Details:

Mass: 14431.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P06367

#17: Protein

C5 c5 40S ribosomal protein S15 / RIG protein / RP52 / S21 / YS21

Details:

Mass: 15830.597 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q01855

#18: Protein

C6 c6 40S ribosomal protein S16-A / RP61R

Details:

Mass: 15746.292 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX51

#19: Protein

C7 c7 40S ribosomal protein S17-A / RP51A

Details:

Mass: 15820.413 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02407

#20: Protein

C8 c8 40S ribosomal protein S18-A

Details:

Mass: 16940.443 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX55

#21: Protein

C9 c9 40S ribosomal protein S19-A / RP55A / S16a / YP45 / YS16A

Details:

Mass: 15810.930 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P07280

#22: Protein

D0 d0 40S ribosomal protein S20

Details:

Mass: 13797.850 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38701

#23: Protein

D1 d1 40S ribosomal protein S21-A / S26 / YS25

Details:

Mass: 9758.829 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0V8

#24: Protein

D2 d2 40S ribosomal protein S22-A / RP50 / S24 / YP58 / YS22

Details:

Mass: 14518.867 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0W1

#25: Protein

D3 d3 40S ribosomal protein S23-A / RP37 / S28 / YS14

Details:

Mass: 15942.699 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX29

#26: Protein

D4 d4 40S ribosomal protein S24-A / RP50

Details:

Mass: 15231.650 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX31

#27: Protein

D5 d5 40S ribosomal protein S25-A / RP45 / S31 / YS23

Details:

Mass: 11936.076 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E792

#28: Protein

D6 d6 40S ribosomal protein S26-B

Details:

Mass: 11022.989 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39939

#29: Protein

D7 d7 40S ribosomal protein S27-A / RP61 / YS20

Details:

Mass: 8762.195 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P35997

#30: Protein

D8 d8 40S ribosomal protein S28-A / S33 / YS27

Details:

Mass: 7474.652 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E7X9

#31: Protein

D9 d9 40S ribosomal protein S29-A / S36 / YS29

Details:

Mass: 6544.527 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41057

#32: Protein

E0 40S ribosomal protein S30-A

Details:

Mass: 6779.086 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

#80: Protein

e0 40S ribosomal protein S30-A

Details:

Mass: 7006.346 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

Ubiquitin-40S ribosomal protein ... , 2 types, 2 molecules E1 e1

#33: Protein

E1 Ubiquitin-40S ribosomal protein S31

Details:

Mass: 8717.488 Da / Num. of mol.: 1 / Fragment: UNP residues 77-152 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05759

#81: Protein

e1 Ubiquitin-40S ribosomal protein S31

Details:

Mass: 8703.462 Da / Num. of mol.: 1 / Fragment: UNP residues 77-152 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05759

Protein , 4 types, 7 molecules SR sR SM sM Q0 q0 p0

#34: Protein

SR sR Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1

Details:

Mass: 34710.023 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38011

#35: Protein

SM sM Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1

Details:

Mass: 30048.010 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39015

#76: Protein

Q0 q0 Ubiquitin-60S ribosomal protein L40

Details:

Mass: 6032.321 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CH08

#83: Protein

p0 60S acidic ribosomal protein P0 / A0 / L10E

Details:

Mass: 33617.930 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05317

60S ribosomal protein ... , 40 types, 80 molecules L2 l2 L3 l3 L4 l4 L5 l5 L6 l6 L7 l7 L8 l8 L9 l9 M0 m0 M1 m1 M3 m3 M4 m4 M5 m5 M6 m6 M7 m7 ...

#39: Protein

L2 l2 60S ribosomal protein L2-A / L5 / RP8 / YL6

Details:

Mass: 27332.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX45

#40: Protein

L3 l3 60S ribosomal protein L3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1

Details:

Mass: 43719.602 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14126

#41: Protein

L4 l4 60S ribosomal protein L4-A / L2 / RP2 / YL2

Details:

Mass: 39027.926 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P10664

#42: Protein

L5 l5 60S ribosomal protein L5 / L1 / L1a / Ribosomal 5S RNA-binding protein / YL3

Details:

Mass: 33633.633 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26321

#43: Protein

L6 l6 60S ribosomal protein L6-A / L17 / RP18 / YL16

Details:

Mass: 19869.369 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02326

#44: Protein

L7 l7 60S ribosomal protein L7-A / L6 / RP11 / YL8

Details:

Mass: 27555.084 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05737

#45: Protein

L8 l8 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Maintenance of killer protein 7 / RP6 / YL5

Details:

Mass: 28044.621 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P17076

#46: Protein

L9 l9 60S ribosomal protein L9-A / L8 / RP24 / YL11

Details:

Mass: 21605.061 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05738

#47: Protein

M0 m0 60S ribosomal protein L10 / L9 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein

Details:

Mass: 25279.271 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41805

#48: Protein

M1 m1 60S ribosomal protein L11-B / L16 / RP39 / YL22

Details:

Mass: 19654.520 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E757

#49: Protein

M3 m3 60S ribosomal protein L13-A

Details:

Mass: 22472.967 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q12690

#50: Protein

M4 m4 60S ribosomal protein L14-A

Details:

Mass: 15063.870 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P36105

#51: Protein

M5 m5 60S ribosomal protein L15-A / L13 / RP15R / YL10 / YP18

Details:

Mass: 24351.162 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05748

#52: Protein

M6 m6 60S ribosomal protein L16-A / L13a / L21 / RP22 / YL15

Details:

Mass: 22116.029 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26784

#53: Protein

M7 m7 60S ribosomal protein L17-A / L20A / YL17

Details:

Mass: 20458.322 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05740

#54: Protein

M8 m8 60S ribosomal protein L18-A / RP28

Details:

Mass: 20478.059 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX49

#55: Protein

M9 m9 60S ribosomal protein L19-A / L23 / RP15L / RP33 / YL14

Details:

Mass: 21631.121 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX82

#56: Protein

N0 n0 60S ribosomal protein L20-A / L18a

Details:

Mass: 20478.852 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX23

#57: Protein

N1 n1 60S ribosomal protein L21-A

Details:

Mass: 18148.066 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02753

#58: Protein

N2 n2 60S ribosomal protein L22-A / L1c / RP4 / YL31

Details:

Mass: 13580.163 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05749

#59: Protein

N3 n3 60S ribosomal protein L23-A / L17a / YL32

Details:

Mass: 14362.755 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX41

#60: Protein

N4 n4 60S ribosomal protein L24-A / L30 / RP29 / YL21

Details:

Mass: 17661.717 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04449

#61: Protein

N5 n5 60S ribosomal protein L25 / RP16L / YL25 / YP42'

Details:

Mass: 15656.417 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04456

#62: Protein

N6 n6 60S ribosomal protein L26-A / L33 / YL33

Details:

Mass: 14134.588 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05743

#63: Protein

N7 n7 60S ribosomal protein L27-A

Details:

Mass: 15437.166 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H6

#64: Protein

N8 n8 60S ribosomal protein L28 / L27a / L29 / RP44 / RP62 / YL24

Details:

Mass: 16630.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02406

#65: Protein

N9 n9 60S ribosomal protein L29 / YL43

Details:

Mass: 6560.688 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05747

#66: Protein

O0 o0 60S ribosomal protein L30 / L32 / RP73 / YL38

Details:

Mass: 11299.168 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14120

#67: Protein

O1 o1 60S ribosomal protein L31-A / L34 / YL28

Details:

Mass: 12848.962 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H8

#68: Protein

O2 o2 60S ribosomal protein L32

Details:

Mass: 14678.246 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38061

#69: Protein

O3 o3 60S ribosomal protein L33-A / L37 / RP47 / YL37

Details:

Mass: 12045.935 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05744

#70: Protein

O4 o4 60S ribosomal protein L34-A

Details:

Mass: 13412.820 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P87262

#71: Protein

O5 o5 60S ribosomal protein L35-A

Details:

Mass: 13811.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX84

#72: Protein

O6 o6 60S ribosomal protein L36-A / L39 / YL39

Details:

Mass: 11020.063 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05745

#73: Protein

O7 o7 60S ribosomal protein L37-A / L43 / YL35 / YP55

Details:

Mass: 9746.199 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49166

#74: Protein

O8 o8 60S ribosomal protein L38

Details:

Mass: 8714.363 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49167

#75: Protein/peptide

O9 o9 60S ribosomal protein L39 / L46 / YL40

Details:

Mass: 6227.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04650

#77: Protein/peptide

Q1 q1 60S ribosomal protein L41-A / L47 / YL41

Details:

Mass: 3354.243 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX86

#78: Protein

Q2 q2 60S ribosomal protein L42-A / L41 / YL27 / YP44

Details:

Mass: 12115.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX27

#79: Protein

Q3 q3 60S ribosomal protein L43-A / L37a / YL35

Details:

Mass: 9981.756 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX25

Unknown protein chain ... , 3 types, 3 molecules m2 p1 p2

#82: Protein

m2 unknown protein chain m2

Details:

Mass: 13634.798 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#84: Protein/peptide

p1 unknown protein chain p1

Details:

Mass: 4017.944 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#85: Protein/peptide

p2 unknown protein chain p2

Details:

Mass: 3932.839 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

Non-polymers , 4 types, 2558 molecules

#86: Chemical

2-1901 2-1902 2-1903 2-1904 2-1905 2-1906 2-1907 2-1908 2-1909 2-1910 2-1911 2-1912 2-1913 2-1914 2-1915 2-1916 2-1917 2-1918 2-1919 2-1920 ...
ChemComp-MG / MAGNESIUM ION

Details:

Mass: 24.305 Da / Num. of mol.: 1410 / Source method: isolated from a natural source / Formula: Mg

#87: Chemical

2-2024 2-2025 2-2026 2-2027 2-2028 2-2029 2-2030 2-2031 2-2032 2-2033 2-2034 2-2035 2-2036 2-2037 2-2038 2-2039 2-2040 2-2041 2-2042 2-2043 ...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide

Details:

Mass: 286.365 Da / Num. of mol.: 1131 / Source method: isolated from a natural source / Formula: H₁₂N₆Os

#88: Chemical

2-2181 ChemComp-GET / GENETICIN / G418

Details:

Mass: 496.552 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Formula: C₂₀H₄₀N₄O₁₀ / Comment: antibiotic*YM

#89: Chemical

D6-500 D7-101 D9-101 E1-501 O7-101 Q0-500 Q2-501 Q3-501 d6-101 d7-101 d9-101 e1-501 o7-501 q0-201 q2-501 q3-501
ChemComp-ZN / ZINC ION

Details:

Mass: 65.409 Da / Num. of mol.: 16 / Source method: isolated from a natural source / Formula: Zn

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 3.07 ų/Da / Density % sol: 59.96 %
• Crystal grow: Temperature: 277 K / Method: vapor diffusion, hanging drop / pH: 7.5 ; Details: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: SOLEIL / Beamline: PROXIMA 1 / Wavelength: 1 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Jul 1, 2013
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 1 Å / Relative weight: 1
• Reflection: Resolution: 3.6→135.58 Å / Num. obs: 855160 / % possible obs: 100 % / Observed criterion σ(I): -3 / Redundancy: 13.52 % / B_iso Wilson estimate: 115.57 Ų / R_merge F obs: 0.992 / R_merge(I) obs: 0.517 / R_rim(I) all: 0.535 / Χ²: 0.919 / Net I/σ(I): 5.77 / Num. measured all: 12887521

Reflection shell

Diffraction-ID: 1 / Rejects: _

Resolution (Å)	Highest resolution (Å)	Rmerge F obs	Rmerge(I) obs	Mean I/σ(I) obs	Num. measured obs	Num. possible	Num. unique obs	Rrim(I) all	% possible all
3.6-3.7		0.367	3.303	0.96	909240	67259	67248	3.432	100
3.7-3.8		0.489	2.535	1.25	790894	60435	60417	2.637	100
3.8-3.9		0.596	1.96	1.62	724202	54408	54410	2.038	100
3.9-4		0.689	1.627	1.96	670605	49024	49017	1.689	100
4-4.1		0.749	1.36	2.35	601161	44434	44429	1.413	100
4.1-4.2		0.8	1.177	2.69	528223	40290	40286	1.225	100
4.2-4.4		0.856	0.965	3.28	939441	70037	70028	1.003	100
4.4-4.6		0.904	0.76	4.18	799825	58451	58446	0.79	100
4.6-5		0.936	0.586	5.27	1199244	90595	90587	0.61	100
5-10		0.982	0.465	9.42	4902982	279825	279787	0.478	100
10-50		0.993	0.167	20.16	820625	40208	40190	0.171	100
50-100		0.998	0.049	10.62	999	308	287	0.057	93.2
100-150		0.999	0.067	3.16	80	35	28	0.077	80
	150					14

Processing

Software

Name	Version	Classification
XDS		data reduction
PDB_EXTRACT	3.14	data extraction
PHENIX	(phenix.refine: dev_1702)	refinement
XSCALE		data scaling
XSCALE		data reduction

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 3U5B, 3U5C, 3U5D, 3U5E, 3U5F, 3U5G, 3U5H, 3U5I

3u5b
PDB Unreleased entry

3u5c
PDB Unreleased entry

3u5d
PDB Unreleased entry

3u5e
PDB Unreleased entry

3u5f
PDB Unreleased entry

3u5g
PDB Unreleased entry

3u5h
PDB Unreleased entry

3u5i
PDB Unreleased entry

Resolution: 3.6→135.579 Å / SU ML: 0.5 / Cross valid method: FREE R-VALUE / σ(F): 0 / Phase error: 25.83 / Stereochemistry target values: ML

	Rfactor	Num. reflection	% reflection
Rfree	0.2667	17100	2 %
Rwork	0.1898	837844	-
obs	0.1913	854944	99.97 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso max: 324.4 Ų / B_iso mean: 98.7847 Ų / B_iso min: 9.1 Ų

Refinement step

Cycle: final / Resolution: 3.6→135.579 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	179691	222027	10957	0	412675
Biso mean	-	-	145.01	-	-
Num. residues	-	-	-	-	32986

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.018	438061
X-RAY DIFFRACTION	f_angle_d	2.256	650015
X-RAY DIFFRACTION	f_chiral_restr	0.084	79413
X-RAY DIFFRACTION	f_plane_restr	0.01	41776
X-RAY DIFFRACTION	f_dihedral_angle_d	20.751	194723

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection all	% reflection obs (%)
3.6-3.6409	0.36	570	0.274	27900	28470	100
3.6409-3.6837	0.3442	567	0.2689	27834	28401	100
3.6837-3.7287	0.3161	568	0.2486	27824	28392	100
3.7287-3.7759	0.3088	570	0.2376	27904	28474	100
3.7759-3.8256	0.2924	567	0.2207	27760	28327	100
3.8256-3.878	0.3118	571	0.2233	27974	28545	100
3.878-3.9334	0.2946	566	0.2104	27788	28354	100
3.9334-3.9921	0.291	570	0.2044	27891	28461	100
3.9921-4.0545	0.3017	568	0.2045	27854	28422	100
4.0545-4.1209	0.2777	569	0.1866	27902	28471	100
4.1209-4.192	0.2828	568	0.1829	27813	28381	100
4.192-4.2682	0.2682	570	0.1802	27944	28514	100
4.2682-4.3503	0.2665	570	0.1746	27901	28471	100
4.3503-4.4391	0.2579	566	0.1721	27785	28351	100
4.4391-4.5357	0.2672	571	0.172	27927	28498	100
4.5357-4.6412	0.2631	569	0.1712	27904	28473	100
4.6412-4.7573	0.2464	570	0.1633	27910	28480	100
4.7573-4.8859	0.2424	569	0.1591	27915	28484	100
4.8859-5.0297	0.2517	571	0.1667	27936	28507	100
5.0297-5.192	0.2669	570	0.1653	27920	28490	100
5.192-5.3776	0.2442	569	0.1642	27910	28479	100
5.3776-5.5929	0.2424	570	0.1614	27928	28498	100
5.5929-5.8475	0.2391	571	0.1613	27981	28552	100
5.8475-6.1557	0.2401	571	0.1621	27956	28527	100
6.1557-6.5414	0.2606	571	0.1754	27978	28549	100
6.5414-7.0465	0.269	570	0.1795	27979	28549	100
7.0465-7.7555	0.2697	573	0.1868	28055	28628	100
7.7555-8.8776	0.2442	573	0.1867	28068	28641	100
8.8776-11.184	0.2571	574	0.199	28114	28688	100
11.184-135.6753	0.2721	578	0.2417	28289	28867	99

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.567	-0.0995	-0.5679	0.0993	-0.0962	1.1225	-0.0172	0.1637	-0.2515	0.1123	0.0179	0.0938	0.1946	0.068	0.1037	1.0893	-0.6294	0.7686	1.623	-0.4496	1.4775	-111.3248	-7.5504	109.3288
2	0.3668	-0.1639	0.0698	0.6597	0.0681	0.5205	0.1064	-0.3766	-0.4177	0.79	-0.0212	0.093	0.5895	-0.1462	-0.0807	2.6513	-0.5333	0.0025	1.6037	0.1828	1.2372	-48.0104	-27.4932	138.3919
3	0.9612	0.3571	-0.1395	0.8868	0.0727	1.0489	0.2029	-0.1142	0.3473	0.0327	-0.0249	0.5474	0.0175	-0.3813	-0.2079	0.7275	-0.1176	0.1103	1.1737	-0.3671	1.5771	-101.57	10.5215	76.2951
4	0.5329	0.2546	-0.0576	0.5383	-0.0793	0.308	0.1228	0.2751	0.0459	-0.0603	0.0073	0.3837	-0.0119	-0.3689	-0.0881	0.8197	-0.2629	-0.0436	1.5781	-0.3598	1.5188	-100.1395	-28.2783	44.9665
5	0.3708	-0.133	-0.3219	0.4258	0.0439	0.4797	-0.0496	0.1792	0.0874	-0.1599	0.0619	0.4956	0.0365	-0.0629	0.0465	1.0113	0.2936	-0.2329	1.2577	-0.2163	1.903	-79.9338	81.798	70.9567
6	0.4072	-0.3486	0.0719	0.2929	-0.1384	0.8268	0.1751	-0.2972	-0.0941	0.2532	-0.2258	-0.275	0.1334	-0.1267	0.1607	1.6261	-0.6793	0.1148	1.2262	-0.0459	1.7104	-77.2253	-76.3577	89.8067
7	0.1445	0.3012	-0.1096	0.5873	-0.1731	0.6246	-0.3721	0.0325	-0.0232	-0.4794	-0.0266	-0.2002	-0.1258	-0.0068	0.3026	1.1433	0.0425	-0.0575	0.7485	0.112	1.2563	-29.8066	98.5459	48.8435
8	0.5109	0.1545	-0.2394	0.2682	0.0185	0.2809	-0.0838	-0.3469	0.2671	0.2605	-0.1296	0.2904	0.0159	-0.3529	0.0702	1.3737	-0.2659	0.5833	2.0586	-0.8093	1.4657	-98.1596	48.368	135.9211
9	0.8533	-0.0303	0.0341	1.0491	0.1205	0.7681	-0.0674	-0.133	0.3553	0.1762	-0.1135	0.5046	-0.132	0.0776	0.1196	0.9675	0.117	0.1079	0.9515	-0.4041	1.2209	-31.7545	89.303	94.898
10	0.5266	0.0209	-0.2345	0.5374	0.0559	0.3577	0.0805	0.126	0.1002	-0.2644	-0.1943	0.8769	-0.2484	-0.3121	0.0857	1.0307	0.0944	-0.3827	1.5797	-0.2675	2.0098	-96.6237	42.449	47.7359
11	0.082	-0.3009	0.2789	1.2575	-0.6057	1.8971	0.1494	0.2442	0.0214	-0.1905	0.1153	0.3284	0.1568	-0.0383	-0.2537	0.9432	-0.4615	-0.0882	1.5081	-0.0431	1.2023	-86.9806	-32.2379	13.0647
12	0.933	0.5586	0.2855	1.1151	0.0544	0.1782	-0.0534	-0.3435	-0.078	0.3441	-0.2933	0.1727	0.001	-0.0891	0.2783	0.7777	0.0654	0.241	1.2147	-0.3106	1.1326	-52.7314	67.3465	104.8604
13	0.9428	-0.2408	0.1207	0.513	-0.4747	0.455	0.1188	0.2387	-0.0168	-0.238	0.0859	0.0887	-0.0229	0.0489	-0.1649	2.273	-0.3941	-0.1784	2.2651	0.0624	1.7029	-79.5753	-25.0068	-18.9896
14	0.5633	-0.079	-0.3846	0.4253	0.3162	0.8448	0.1138	-0.3574	0.2394	0.5663	-0.3201	0.24	0.1862	-0.4553	0.1448	1.4501	-0.4662	0.2493	1.5818	-0.3563	1.0196	-61.1446	30.2995	131.4821
15	0.0487	-0.0487	0.0133	0.036	-0.0176	0.0027	0.3027	-0.184	-0.3638	0.6613	-0.0923	-0.0882	0.3783	-0.0158	-0.0727	2.0055	-0.5524	-0.5509	0.7276	0.2105	1.6495	-45.9849	-39.3034	115.1982
16	0.3539	0.0806	-0.1197	1.3689	0.2121	0.9733	0.0201	-0.1988	-0.0052	-0.2517	-0.1248	-0.0971	0.0827	-0.0199	0.0237	0.7621	-0.1275	0.2187	1.211	-0.561	1.5804	-47.2376	-69.0848	21.1136
17	0.3669	0.4335	-0.1093	0.9254	-0.2273	0.3859	-0.1731	0.0504	0.3635	0.1044	-0.0577	-0.108	-0.0495	-0.0416	0.1814	1.2491	-0.7304	0.2572	1.1554	-0.6258	1.7901	-98.7608	-76.2655	72.3016
18	0.034	-0.0498	-0.001	0.0887	0.1611	0.3736	0.1289	0.1573	-0.3064	0.041	-0.0292	0.1544	-0.02	0.1253	0.0799	0.9599	-0.5575	0.3259	1.2068	-0.5201	1.5946	-112.597	-29.505	97.3951
19	0.1777	0.1864	-0.064	0.6528	-0.0326	0.0353	0.2073	-0.0825	-0.1758	0.1799	0.0665	-0.3013	0.1947	0.1072	-0.2115	0.9076	-0.1729	-0.101	1.3754	-0.3533	1.8826	-49.819	-89.1972	48.4046
20	0.2397	-0.1199	0.1378	0.2337	0.1739	0.3955	-0.1228	0.0878	-0.2093	-0.0295	-0.1178	-0.0415	0.5167	-0.2944	0.0356	1.1344	-0.4783	0.1659	1.0829	-0.4096	2.1619	-83.2933	-94.1986	50.7984
21	2.0238	0.611	0.37	0.7056	-0.0466	0.4971	0.2841	-0.04	0.3193	0.0797	-0.0377	0.3602	-0.0657	-0.1206	-0.0738	0.6308	-0.3648	-0.0024	1.6262	-0.5521	1.7223	-108.0159	-54.7781	42.0941
22	1.2585	-0.0794	-0.2082	0.1565	-0.2329	0.7167	0.0885	-0.0245	0.2039	0.2093	0.1277	0.249	-0.221	-0.2244	-0.2725	1.0449	-0.2317	0.812	1.7941	-0.441	1.8529	-111.475	12.7057	100.7999
23	0.7714	0.0588	0.1133	0.2367	-0.1688	0.1614	0.1412	0.0053	0.4405	0.2443	-0.1395	0.2906	-0.092	-0.0864	-0.0311	0.6637	-0.1992	0.5285	1.5962	-0.4765	1.6037	-90.4257	33.7385	101.3612
24	0.3177	-0.1529	-0.0124	0.6862	0.5247	0.8178	-0.1737	0.0716	0.1562	0.0358	0.0438	0.1869	0.1753	-0.2137	0.1239	0.7462	-0.0253	0.0445	0.8945	-0.1394	1.0232	-54.8762	22.0219	55.998
25	0.8675	0.0952	0.2357	0.4723	-0.0136	0.3698	-0.1725	0.1819	0.1749	-0.4322	0.0159	0.3939	-0.096	-0.4145	0.0496	1.3891	0.209	-0.4991	1.3429	0.1421	1.593	-73.72	77.6859	33.3293
26	0.0426	-0.0257	0.0153	0.1958	-0.1137	0.2219	-0.0478	-0.3432	0.2054	0.1892	-0.1729	-0.0888	-0.0934	0.2418	0.1693	1.9682	-0.2666	-0.4943	1.3909	0.1525	2.2109	-64.5874	-101.3305	80.4917
27	0.5363	0.1476	-0.1279	0.3349	0.1014	0.4432	-0.1476	-0.3321	-0.1309	0.328	0.1292	0.2753	0.2267	-0.1126	0.0409	1.6486	-0.6158	0.0424	1.0992	-0.0197	1.3216	-62.096	-22.4772	108.8584
28	0.6795	-0.1877	0.1605	0.5538	-0.1514	0.7029	0.224	-0.1554	0.1274	0.4732	-0.1041	0.0211	-0.1797	-0.1846	-0.1217	1.6587	-0.7525	0.535	2.0404	0.0325	1.2679	-81.4748	17.6202	140.6376
29	0.2655	0.1581	0.2887	0.7483	-0.0316	0.3767	0.0044	-0.2569	-0.1574	0.3029	0.0973	-0.0152	-0.0105	-0.068	-0.0426	1.9685	-0.1914	0.3348	1.7329	-0.1613	1.5866	-76.8499	-56.2829	106.3606
30	1.1869	-0.0285	-0.7167	0.5767	-0.1164	0.5464	0.2048	-0.0293	0.0721	0.1235	-0.1328	0.1219	0.1375	-0.2495	-0.0047	0.9398	-0.303	0.0907	1.2842	-0.4968	1.4628	-80.1865	-46.661	35.8318
31	1.767	-1.5146	0.0009	1.346	-0.1894	0.6939	0.0129	-0.0893	-0.1381	-0.1519	0.0771	0.634	-0.1109	-0.2789	-0.0393	1.1534	-0.1899	-0.1067	1.4929	-0.3906	1.3243	-80.6623	13.5838	36.8872
32	0.0557	0.0989	0.0697	0.1973	0.2259	0.285	0.0795	-0.1659	0.121	-0.2944	-0.1062	0.0574	-0.0014	-0.0512	0.0289	1.7649	0.0189	-0.0038	1.9486	-0.4207	1.2786	-60.6954	-42.0142	-7.6097
33	0.7368	0.1938	-0.0643	0.3981	-0.0997	0.2086	-0.0236	-0.2889	0.0103	-0.0414	-0.1347	-0.2015	0.0446	-0.0879	-0.0112	1.2217	-1.0249	0.6219	1.6986	-0.521	1.6752	-133.1603	-56.857	85.8134
34	0.2236	-0.1015	-0.0117	0.055	-0.0916	0.0161	0.1844	-0.0104	0.0554	0.0909	-0.139	-0.0075	0.0179	-0.0306	-0.0054	1.0686	-0.2247	-0.0211	1.1047	-0.0845	1.3552	-55.2589	-39.4793	40.3729
35	0.2124	0.0407	-0.498	0.3855	-0.0103	1.0589	0.0268	-0.1262	0.1259	0.1995	-0.1158	-0.0338	0.0637	-0.1632	0.0784	0.6617	-0.3199	0.1117	0.9117	-0.0838	0.6671	-3.5057	-3.654	124.2401
36	0.266	-0.1763	0.0712	0.5181	-0.0738	0.8022	0.0023	0.0615	0.1937	0.045	-0.0487	-0.0982	-0.2538	0.0723	0.0375	0.4403	0.0116	0.1177	0.5059	0.1415	0.8459	32.2695	61.4878	39.1445
37	0.1675	0.1334	-0.0452	0.1484	-0.0909	0.2976	0.0376	-0.0349	-0.1315	0.1469	-0.1238	-0.2282	0.0515	0.1159	0.0964	0.5213	-0.0765	-0.0849	0.6995	0.1094	0.826	91.9766	-24.6146	74.1066
38	0.45	-0.2122	0.1394	0.6876	-0.1599	0.7378	0.051	-0.003	-0.1921	-0.0331	0.1956	-0.0927	0.3058	0.0931	-0.2709	0.9904	-0.1969	-0.1442	0.703	-0.2804	1.1896	23.9428	-92.6909	30.2181
39	0.0515	0.0334	-0.1173	0.5426	-0.3122	1.0019	-0.0069	-0.1271	-0.0333	-0.0894	-0.2985	-0.5825	-0.1258	0.4218	0.2973	0.4691	-0.0975	0.1068	0.6786	0.1035	0.8121	105.914	12.1874	13.3359
40	1.1154	-0.1764	-0.1936	1.0074	0.4105	1.351	-0.1174	0.0664	0.2772	-0.0705	0.0269	-0.447	0.0634	0.1128	0.0513	0.4863	-0.0452	0.1139	0.4916	-0.0661	0.6595	75.6916	-31.0925	17.4363
41	0.3673	-0.2265	-0.1538	0.7791	0.4762	0.2138	0.0389	-0.2712	-0.2466	0.4897	-0.2083	0.0752	0.0383	-0.1188	0.1137	1.2064	-0.4041	0.152	1.3646	0.1835	0.7568	27.3975	-39.5622	161.2057
42	1.4902	-0.3226	-0.43	0.7394	0.0567	0.3605	-0.0755	0.5608	0.4042	-0.2831	0.0935	0.3544	-0.2708	-0.1627	-0.0071	0.5968	0.0502	-0.1579	1.0784	0.2169	0.7941	20.9169	33.5142	-8.5335
43	0.7721	-0.2479	-0.0365	0.6526	-0.0135	0.7445	-0.2306	0.0663	-0.067	-0.1722	-0.1823	0.3068	-0.1875	0.0009	0.31	0.6738	-0.2271	-0.1639	0.952	-0.0289	0.7781	11.3297	-26.5183	12.577
44	0.9062	-0.072	0.0378	0.6228	0.0634	0.7833	0.0856	0.0955	-0.2258	-0.1083	-0.1061	0.5444	0.5262	-0.6245	-0.1437	0.9835	-0.3649	-0.1679	1.1379	-0.0945	1.4777	-12.8469	-78.199	29.6456
45	0.3101	-0.0436	0.1281	0.7049	-0.3792	0.7752	0.0364	-0.1384	-0.085	0.0077	-0.069	-0.0755	0.2793	0.3281	0.0776	0.7792	-0.022	-0.0999	0.9736	0.2591	0.7995	70.3212	-54.8724	112.0488
46	1.1131	0.257	0.1865	0.276	0.0346	0.5698	0.2223	0.2942	0.4282	0.0242	-0.1291	-0.0415	0.1088	0.107	-0.0261	0.6255	-0.2097	0.1752	0.8883	0.0187	0.5409	68.8258	14.5484	-15.1658
47	0.4442	-0.0103	-0.094	-0.008	-0.0125	0.4528	0.0131	-0.3632	-0.0622	0.2485	-0.0868	-0.1814	0.096	-0.1258	0.0882	0.8083	-0.3468	-0.0572	1.0763	0.2543	0.7634	41.2675	-31.8746	127.7879
48	0.8943	-0.167	-0.217	0.4603	-0.0092	0.4066	0.1786	0.3439	0.2096	0.0357	-0.0016	0.1119	-0.1032	-0.1574	-0.2036	0.5038	-0.0059	0.0123	0.6188	0.1384	0.4778	56.1379	30.3674	12.786
49	0.3	-0.1112	0.5151	0.9684	0.1512	0.994	0.2452	0.2828	-0.0102	-0.1277	-0.0413	-0.3751	0.2552	0.3099	-0.1896	0.5627	-0.0516	0.025	0.4582	-0.0349	0.6735	72.9607	40.4965	68.4213
50	0.8431	-0.004	-0.0143	0.4406	-0.2204	0.2999	0.0047	-0.1979	-0.2844	0.0663	-0.1551	0.0244	0.2384	0.049	0.1078	0.5123	0.0021	0.0284	0.5761	0.1984	0.9925	80.3013	-49.6865	66.104
51	2.0413	-0.1404	0.2249	0.5205	0.0001	0.5865	0.0598	-0.1367	0.1441	0.1079	0.0008	-0.324	-0.2682	0.0836	-0.1141	0.9237	-0.1761	0.1051	1.0268	-0.1885	0.8236	36.5664	61.9135	112.0827
52	1.266	0.4271	-0.8959	0.5344	-0.589	1.8463	0.2012	-0.0611	0.174	0.0809	0.0287	0.0264	-0.0423	0.1043	-0.1638	0.7611	-0.0225	0.0209	1.1793	-0.4502	1.1832	-15.6258	52.198	118.6113
53	1.0257	-0.396	-0.1494	0.5022	0.1482	0.2421	-0.2061	-0.215	-0.033	0.2852	-0.1256	0.4373	-0.0808	-0.6271	0.2079	1.1327	-0.0353	0.0336	1.4109	-0.4477	1.1145	-48.6975	58.5154	133.255
54	0.4064	0.2697	-0.414	0.7156	-0.0584	0.4503	0.0118	0.3031	-0.0302	0.013	-0.0793	0.2119	0.1532	-0.0999	0.0128	0.6653	-0.0688	-0.0533	0.9388	-0.0483	0.607	49.0718	-13.8428	-4.4803
55	0.1048	0.1667	-0.2482	0.2725	-0.267	0.4808	-0.0326	0.1471	-0.1437	-0.1558	0.0923	-0.1728	0.1209	-0.094	-0.0145	0.7128	-0.0852	-0.0738	0.6796	-0.2263	0.9672	45.8951	-54.5876	29.7077
56	0.5937	0.1417	0.503	1.4665	-0.1483	1.363	-0.0242	-0.2878	0.2719	0.1911	-0.3217	-0.1866	-0.3058	-0.0714	0.1771	1.4617	0.027	0.079	1.0139	-0.5074	1.0753	23.4776	89.8961	119.1129
57	0.8696	0.1776	0.1273	1.1841	-0.1183	0.2391	0.055	0.0545	0.1873	0.0271	0.0177	0.3658	0.0823	-0.1534	-0.1255	0.5836	0.0648	0.0398	0.7816	0.0983	0.9772	-7.7245	45.903	48.3142
58	1.0214	-0.7276	0.3649	0.7861	-0.0263	0.4441	-0.1085	0.1499	1.068	-0.2261	0.1909	0.1792	-0.98	-0.4987	-0.0914	1.0005	0.0909	0.0606	0.872	-0.0886	1.7255	-4.9964	81.7407	57.2899
59	0.7642	-0.2285	0.143	0.3702	0.1127	0.3975	-0.1886	-0.3397	-0.0837	0.1433	0.0455	-0.0685	-0.1395	0.1717	0.0068	1.1249	-0.4978	-0.0394	1.2604	-0.1706	0.6062	51.4928	25.0537	143.6493
60	0.521	0.2834	-0.1135	0.8313	0.1528	0.4467	0.2269	-0.4097	-0.0944	0.1529	-0.0717	-0.1632	0.1227	0.1204	-0.0833	0.6746	-0.2869	-0.1721	1.2395	0.2255	0.9005	100.0771	11.5589	114.8453
61	0.5531	-0.0921	-0.1558	0.29	0.0682	0.9545	-0.2569	-0.3139	-0.1462	0.0131	-0.0055	0.081	-0.1622	0.1081	0.1221	1.4164	-0.2822	0.4679	1.7052	-0.416	0.7982	-8.6878	27.5124	173.7545
62	0.1686	0.1324	0.0119	0.8342	-0.3054	0.381	0.1844	-0.1071	-0.183	0.1597	-0.2389	-0.0849	0.1136	0.1747	0.0701	0.7275	-0.0364	-0.0306	0.8368	0.1842	0.892	65.7885	-53.9458	84.3075
63	0.1735	0.0283	0.1752	1.5398	-0.0378	0.6702	0.0398	-0.053	-0.0467	0.0877	0.0782	-0.3958	0.2799	-0.1137	-0.0537	0.7594	-0.0381	-0.1651	0.7143	-0.0817	1.3043	55.6314	-56.0191	51.6292
64	0.3114	0.0739	0.2164	0.659	-0.1692	0.9147	0.0784	-0.1266	0.0045	0.0719	-0.1612	0.2139	0.0973	-0.3321	0.0468	0.7676	-0.2152	0.2519	1.702	-0.3303	0.8322	-33.2462	23.562	152.4687
65	1.487	0.9284	0.0085	2.5812	0.0053	1.7485	0.1634	-0.1679	0.1117	0.0464	0.0098	0.0024	-0.1664	0.1662	-0.1515	0.6971	-0.0399	0.2303	0.6939	-0.1542	0.8035	43.7156	72.1608	81.5912
66	1.4895	-0.032	0.3675	0.4372	-0.043	0.786	-0.066	0.0738	0.0649	0.0942	-0.021	-0.074	-0.0245	0.1259	0.0311	0.5287	-0.0497	0.0193	0.6293	0.141	0.6446	89.3327	-0.0333	58.4172
67	1.6347	0.0362	-0.436	1.5292	-0.0402	1.8918	-0.0501	0.0138	0.2094	0.0181	0.0727	-0.24	-0.3312	0.1689	-0.0772	0.4802	-0.082	0.0521	0.5269	-0.0005	0.5365	81.5012	14.4887	22.9006
68	0.5139	0.011	-0.1736	0.023	-0.1105	0.444	-0.1226	-0.2058	-0.0257	0.0326	-0.1615	0.0457	-0.1383	-0.0086	0.3266	1.046	-0.2306	0.1518	1.2467	-0.3528	0.759	5.3041	27.6829	144.4592
69	0.3447	-0.233	-0.135	0.6778	0.2476	0.3122	0.059	-0.396	-0.0643	0.1444	0.1877	-0.3409	0.2166	0.1239	-0.2219	0.9388	-0.3027	-0.0888	1.4272	-0.0791	0.729	72.2806	-0.6533	142.2989
70	0.3813	-0.4651	-0.0936	0.7435	0.4826	0.7739	-0.0086	-0.2211	-0.226	0.2979	-0.2351	0.2326	0.2416	-0.2396	0.1935	1.1345	-0.4727	-0.0564	1.0062	0.2034	0.8485	35.45	-63.3446	127.5843
71	0.1585	-0.099	-0.1948	0.9182	-0.1609	0.7306	0.0474	-0.13	0.0248	0.341	-0.1462	0.1907	0.1721	-0.0733	0.0928	0.7298	-0.2535	0.1092	0.8906	-0.0656	0.6053	52.5009	2.9231	118.1725
72	0.909	-0.6185	-0.3424	1.9602	0.3094	0.7179	0.1075	-0.1451	0.1903	0.2475	0.0153	0.0526	-0.2249	0.072	-0.0941	1.3559	-0.3442	0.1695	1.3886	-0.3979	0.5962	28.1261	61.7224	155.5715
73	1.5758	-0.0068	0.1547	0.82	-0.0168	0.6712	-0.0402	0.1145	0.1332	0.0796	-0.1537	-0.0386	-0.0919	0.116	0.1889	0.8601	-0.3955	0.1971	0.9179	-0.112	0.7214	58.4696	24.0233	112.5668
74	0.4028	0.2948	0.0791	1.7924	-0.6188	2.08	-0.3039	0.1793	0.0644	-0.1506	-0.2135	-0.0637	0.0222	0.0777	0.3814	0.5383	0.1156	-0.1218	1.0369	0.0822	0.7836	7.81	17.7335	3.0133
75	0.5213	0.2992	-0.6204	0.4683	-0.5537	0.877	0.1356	-0.1339	0.0211	0.1096	-0.2275	0.0624	-0.0875	0.105	0.0751	0.7775	-0.1183	0.0967	1.1118	-0.0728	1.0361	-35.981	5.9709	81.8173
76	0.371	0.4085	0.0929	2.1761	0.8571	1.4212	0.1722	-0.0505	-0.2631	0.5058	-0.0918	0.142	0.3722	-0.3503	-0.0689	0.8979	-0.2529	0.0491	0.8066	0.1293	0.8959	19.6642	-60.597	77.2217
77	0.2113	0.0215	0.1453	0.449	-0.2785	0.849	0.2204	-0.2115	0.1198	0.0676	0.1373	0.0618	-0.3456	-0.1795	-0.2049	0.5508	-0.1018	0.3359	1.0772	-0.3114	0.7275	-18.3136	14.1833	123.446
78	0.9485	0.1303	-0.3185	0.0216	-0.0336	0.7087	-0.0932	-0.1975	-0.0267	0.0479	-0.2181	-0.0493	0.3763	0.055	0.2151	0.663	0.2757	0.6721	0.9243	0.5093	1.4199	292.6608	-1.2182	217.6567
79	0.5573	0.4386	0.0809	1.0877	-0.2232	0.3436	0.0206	0.4218	-0.3138	-0.3748	-0.0424	-0.2383	0.1282	-0.0919	0.0661	1.2558	0.2534	0.2709	1.0125	-0.0616	0.8805	236.3112	-24.7669	177.5998
80	1.2337	-0.3729	0.002	0.4378	0.0326	0.9204	-0.0134	0.0256	-0.063	-0.072	-0.1713	-0.3815	-0.0406	0.1198	0.1787	0.7248	-0.013	0.0195	0.7301	0.4394	1.474	275.8827	17.3624	247.4276
81	0.459	0.0039	-0.0288	0.3533	-0.1116	0.4136	0.4875	-0.3066	0.5046	0.48	-0.2736	0.0291	-0.7086	0.2548	-0.2735	1.552	-0.2704	0.2744	0.7861	-0.0827	1.0048	271.8739	-22.4367	278.7324
82	0.4293	-0.0532	-0.3243	0.4016	-0.0089	0.6391	0.1122	-0.0204	0.1053	0.1077	-0.1839	-0.4054	-0.3164	0.3643	0.0531	0.9925	-0.1614	-0.0451	0.5973	0.2525	1.6145	251.3088	87.9718	245.1335
83	1.0142	0.3451	0.3416	0.5446	-0.0237	1.785	-0.0872	0.2057	0.1469	-0.3331	0.0611	-0.0684	0.5593	-0.3215	0.0279	1.0606	0.0021	0.2715	0.8513	0.1282	0.7264	253.5077	-70.0179	231.6536
84	1.0391	-0.0757	-0.3046	0.7386	-0.0228	0.6377	-0.0769	0.0489	0.137	0.4409	-0.2557	-0.206	-0.3527	-0.0634	0.1537	1.1919	0.0531	-0.0127	0.5318	0.1296	1.0308	195.9658	103.5686	256.896
85	0.5112	-0.0202	0.177	0.001	0.0609	0.9587	-0.1866	0.0912	0.3008	-0.3718	-0.1089	-0.2506	-0.3264	0.0736	-0.1659	1.2282	-0.1017	0.3659	1.2761	0.5665	1.2001	283.456	53.2686	186.9065
86	0.6639	0.1162	0.0639	0.868	0.0662	0.7375	-0.1543	0.1371	0.1203	-0.1729	-0.1903	-0.3472	-0.0549	-0.1245	0.2758	1.132	0.1981	0.2282	0.6149	0.2586	0.8597	208.6078	92.5565	211.8469
87	0.6977	-0.0163	0.1247	0.8576	0.0414	0.8558	0.1079	0.0017	0.3003	0.3127	0.1012	-0.8363	-0.1231	0.134	-0.1644	0.9528	-0.0472	-0.3979	0.8236	0.2216	1.9248	264.3369	50.2235	272.9519
88	0.1858	-0.0313	0.1581	0.4522	0.1371	0.8003	0.1165	-0.4183	0.2374	0.4806	0.0633	-0.3057	-0.0775	0.2556	-0.1272	2.1955	-0.4273	0.3795	1.101	-0.3005	1.4052	255.2891	-26.5084	308.5186
89	0.9741	-0.5724	0.4616	1.643	-0.3726	0.5627	0.0985	0.1899	-0.0618	-0.4936	-0.1019	-0.345	-0.418	-0.0162	0.0277	1.2975	0.08	0.4284	0.781	0.3365	1.0214	231.6382	71.9213	208.2867
90	0.3101	0.1396	0.0565	0.1337	0.1186	0.1194	0.1076	-0.224	0.2406	0.2527	0.0316	-0.0916	-0.1103	-0.0093	-0.1001	3.0887	-0.5473	0.8489	2.2655	-0.3982	1.9112	244.8707	-19.3433	340.2988
91	0.4894	0.1801	-0.2134	0.63	-0.0243	0.5514	-0.0912	-0.006	-0.1101	-0.5195	-0.2152	-0.2634	-0.2148	0.3239	0.2343	1.1953	0.2438	0.3137	1.1095	0.2847	0.7387	246.5822	33.8745	184.6609
92	0.3979	0.2546	0.1873	0.9072	0.1703	0.649	0.1911	0.0866	-0.1413	-0.1286	-0.2955	0.1635	0.2138	0.3016	-0.0965	1.2082	0.4408	0.1201	0.9687	-0.0513	0.736	230.2811	-36.4539	199.9986
93	1.5219	-0.0701	-0.0604	0.9039	0.2914	1.2114	0.1692	0.2162	0.4073	0.3231	-0.0063	0.2987	-0.2143	-0.4008	-0.1773	0.7796	0.1592	0.4879	0.8845	0.2676	1.0412	213.8614	-59.6613	295.261
94	1.2863	-0.234	-0.5686	1.3087	0.331	0.8691	-0.2603	-0.1756	0.2693	-0.0838	0.238	-0.1383	0.2982	0.1034	0.0716	1.0187	0.1583	0.294	0.4969	0.199	0.8932	272.3084	-70.6771	252.0024
95	0.1961	0.3358	-0.158	0.7504	-0.6742	0.9594	0.1828	-0.1023	-0.1506	0.1011	-0.3475	-0.2832	0.2149	-0.073	0.1735	0.8024	0.2555	0.378	0.9593	0.3626	1.2583	292.0675	-25.1175	230.2223
96	0.7292	-0.0687	0.012	1.3436	0.054	0.5322	-0.0266	0.6058	0.1707	-0.3226	0.256	0.422	0.1267	-0.6258	-0.2382	0.7922	-0.1496	0.0673	0.9706	0.402	0.8859	220.0109	-80.9552	268.9793
97	1.4258	0.387	0.1011	1.0615	-0.2089	1.0296	0.0264	-0.1635	-0.0978	-0.0403	-0.1012	-0.2426	0.3403	0.065	0.0703	1.0469	0.1206	0.1207	0.5417	0.2082	0.8459	253.373	-87.38	271.3093
98	1.7977	0.109	0.3931	1.4024	0.1803	1.7792	0.4783	-0.3487	-0.0772	0.6323	-0.1447	-0.4759	-0.2322	0.3569	-0.2569	0.8517	-0.0625	-0.1269	0.77	0.1252	1.0827	278.898	-49.5236	283.688
99	0.8658	-0	-0.2891	0.7501	0.2788	1.7387	0.1099	-0.0824	0.1682	-0.2802	-0.1384	-0.5392	0.0536	0.5014	0.071	0.8325	0.0294	0.2478	0.9486	0.4673	1.3741	290.3746	19.1822	225.0386
100	0.8108	-0.1639	0.136	0.6323	0.0397	0.8294	0.2216	-0.2905	0.2261	-0.2074	-0.0471	-0.2646	-0.0556	0.0757	-0.0976	0.7468	-0.0566	0.3737	0.8754	0.3396	1.2152	269.185	39.3338	219.778
101	0.6244	0.1237	-0.3723	0.5822	-0.6231	0.7918	0.0924	0.2465	0.1082	0.0373	0.0155	-0.037	0.12	-0.1713	-0.1068	0.7419	-0.0698	0.1264	0.5539	0.1577	0.7556	225.8056	27.6788	257.6962
102	0.9613	0.2029	0.5989	0.4953	0.0433	0.6206	-0.1634	-0.2886	0.0214	0.0454	-0.0497	-0.4392	-0.3838	0.1085	0.1532	1.3891	-0.0328	-0.267	0.7226	-0.0518	1.0549	238.0684	85.2336	280.8241
103	2.2504	1.0747	0.0613	1.6754	-0.1282	1.7154	0.0274	0.3358	-0.337	-0.2568	0.0626	0.0711	0.212	-0.2309	-0.0349	1.3742	-0.2951	0.12	0.7505	0.0381	0.9555	238.4238	-94.2449	239.6119
104	0.6399	0.3368	0.3331	0.9741	0.3224	0.8192	-0.3399	0.013	-0.5208	0.146	0.3516	-0.3779	0.08	0.2156	-0.0207	0.9178	0.2324	0.2296	1.0191	0.1457	1.0053	244.4897	-18.1329	209.0882
105	1.0243	0.2201	-0.146	0.7909	0.354	0.2187	-0.0816	0.1173	-0.2182	-0.2914	-0.1072	-0.1779	0.1523	0.3496	0.1574	1.2125	0.2693	0.5804	1.307	0.4406	1.1006	268.5015	21.5488	179.9335
106	1.6565	0.259	-0.1967	1.2245	0.0174	2.9797	0.0395	0.4373	-0.0659	-0.534	0.061	0.039	-0.1673	-0.1535	-0.0655	1.4702	0.1483	0.2436	1.2406	0.2528	0.6986	256.4115	-50.3704	214.9611
107	2.3581	-0.217	-0.4417	1.7206	0.2488	0.3201	0.0397	-0.3543	0.1272	0.3547	-0.2142	0.2872	-0.0866	0.0988	0.1388	1.0964	0.1164	0.481	0.6801	0.1222	1.0723	250.227	-39.7557	285.1493
108	1.0934	0.89	-0.1005	1.031	0.218	0.3731	-0.2698	-0.2121	-0.1599	0.3521	-0.0317	-0.4965	-0.0163	0.4895	0.2601	1.2859	-0.1054	-0.2278	1.0293	0.3909	1.3383	247.8249	20.902	281.8335
109	0.4478	-0.1234	0.5425	0.5071	-0.1457	0.7391	-0.0831	0.2151	0.1018	-0.0895	0.1214	-0.0086	0.2125	0.2999	0.046	2.4423	-0.0232	0.4637	1.9711	-0.4225	1.6451	226.0919	-34.1631	323.25
110	1.0588	0.2647	-0.2671	0.9172	-0.0872	0.7979	-0.0497	-0.046	-0.4765	-0.3109	-0.1552	-0.6042	0.339	0.7634	0.1089	0.8046	0.4011	0.2764	1.3738	0.2142	1.4442	308.7202	-52.85	243.096
111	0.1428	0.0031	0.1834	0.3699	-0.0849	0.4438	0.2738	-0.2157	-0.0221	-0.2045	0.3563	0.3073	-0.0926	-0.2655	0.1562	0.8059	0.0489	0.3498	0.6162	-0.0886	0.8438	216.1013	-39.2239	281.8288
112	0.5439	-0.0256	-0.5875	0.2291	0.1994	0.8252	0.1585	0.1585	-0.1492	-0.2231	-0.0645	-0.0622	0.1585	0.0634	-0.1275	1.0502	0.1888	0.0509	0.9102	-0.1119	0.4489	190.3613	-6.2891	185.0037
113	0.8042	-0.0893	0.1451	0.6203	-0.0605	0.7244	0.118	0.0626	0.151	-0.0444	-0.0727	-0.0335	-0.2486	-0.0458	-0.0606	0.558	0.019	0.0987	0.3277	0.1152	0.5207	135.5446	66.4691	251.8015
114	0.0973	-0.0412	0.0969	0.171	0.1325	0.4033	0.0233	0.1392	-0.0534	-0.1889	0.015	0.2946	0.1452	-0.1272	-0.0233	0.8369	-0.0306	-0.3433	0.7495	-0.051	0.8539	86.722	-25.9019	216.1011
115	0.6784	-0.1961	0.0019	1.2668	-0.2428	0.5548	0.0695	-0.0788	-0.2437	0.0318	0.1153	0.2164	0.2542	-0.0009	-0.223	0.7662	-0.0122	-0.1481	0.3652	0.0869	0.8847	144.0502	-84.7603	282.4741
116	0.4512	-0.2693	-0.2147	0.951	0.4886	0.8032	0.0824	-0.0907	-0.2617	0.1616	-0.0835	0.3702	0.1757	-0.2496	0.0027	0.4415	0.0045	0.0503	0.7173	0.2056	0.8938	59.2443	17.0549	267.416
117	0.7377	-0.0147	-0.2571	0.8842	-0.2589	1.3024	-0.0316	0.0741	-0.193	0.025	-0.0233	0.3584	0.1874	-0.0782	0.0861	0.6042	-0.0582	-0.033	0.3483	0.0538	0.6335	90.4735	-24.9526	275.2715
118	0.356	0.1615	0.0664	0.5322	-0.1497	0.2743	0.1868	0.459	-0.2831	-0.3683	-0.1263	-0.1488	0.3154	0.215	-0.0402	1.9713	0.1826	-0.0779	1.2974	-0.353	0.7852	168.6386	-47.8314	147.2533
119	2.2909	0.4247	-0.314	0.9638	0.0962	0.3146	0.0665	-0.2687	-0.0903	0.2162	-0.0433	-0.1552	-0.2051	-0.004	-0.041	0.6093	-0.0331	0.0482	0.4061	-0.0142	0.3807	137.2232	44.4968	304.0455
120	0.9516	0.1293	-0.0208	0.8796	0.2941	0.613	-0.2923	-0.1804	-0.0053	0.4445	-0.0795	-0.3172	-0.1675	0.0518	0.2729	0.9279	0.0929	-0.246	0.4028	-0.035	0.6049	153.3188	-16.209	292.1899
121	1.1467	0.0571	-0.2743	0.3037	-0.044	0.554	-0.0622	0.1611	-0.318	0.0162	-0.0933	-0.2513	0.2137	0.1631	0.1274	0.8656	0.0866	-0.0531	0.3901	-0.0258	0.8222	180.1274	-69.2491	288.5147
122	1.0682	1.0578	-0.2781	3.2855	0.0327	0.6664	0.0933	-0.1797	-0.2566	0.4545	-0.2256	-0.0973	0.158	0.1448	0.0855	1.2204	-0.4773	-0.4481	0.8487	0.2928	1.715	172.726	22.1601	348.2255
123	0.1861	0.1026	-0.0611	0.6059	0.0095	0.8472	0.0564	-0.0398	-0.141	-0.3411	-0.0039	-0.1404	0.3147	-0.3261	-0.1018	1.2766	-0.0154	-0.2184	0.8264	-0.1676	0.6906	116.8037	-59.4596	187.7738
124	1.1197	-0.2555	0.415	0.1419	-0.1705	0.8277	-0.206	0.0238	0.1343	-0.0923	0.1586	0.0318	-0.069	-0.2948	0.0123	0.6559	0.0643	0.1183	0.5157	0.0735	0.5079	89.4213	24.6808	302.7227
125	0.1231	-0.009	-0.0681	-0.0003	-0.0633	0.4751	-0.014	0.0836	-0.2199	-0.5009	-0.1046	0.2905	0.0082	0.1103	0.0552	1.4533	0.1557	-0.1544	0.906	-0.2706	0.6568	147.9968	-37.0268	175.7827
126	0.7411	-0.0271	0.0856	0.4096	0.0434	0.3607	-0.0239	-0.0801	0.1597	0.0766	0.0633	-0.1257	0.0343	-0.119	-0.0749	0.5248	0.0176	0.0772	0.2762	0.0231	0.4134	107.4543	37.608	276.223
127	1.1309	0.0199	0.4959	0.4246	-0.2974	0.6488	0.0368	0.1061	0.052	-0.0662	0.0458	0.3107	0.2388	-0.0712	-0.0418	0.7386	0.1451	-0.0843	0.4738	0.148	0.5954	108.3525	41.2907	212.9034
128	0.5456	-0.2569	-0.0555	0.2201	-0.0642	0.1081	0.1269	0.1728	0.1076	-0.3024	-0.2158	0.1939	0.0762	-0.0161	0.0222	0.7123	-0.1083	-0.221	0.6565	-0.1651	0.8173	96.89	-49.2586	229.5199
129	1.5737	0.518	-0.2727	0.5065	-0.1033	0.0478	-0.007	0.2783	0.1215	-0.1674	0.0419	0.0542	-0.0296	-0.082	-0.008	1.1122	0.1453	-0.0992	1.2412	0.1539	0.4698	147.119	58.3084	180.2257
130	0.9061	-0.317	-0.2712	0.5312	0.198	0.6562	0.193	0.121	0.1267	-0.0245	0.0267	0.1395	-0.0276	-0.21	-0.1653	1.1331	0.0845	0.0178	0.9714	0.1183	0.77	199.4446	50.6488	185.9781
131	0.6781	0.206	0.2489	0.0872	0.0894	0.0958	-0.1284	0.1596	0.1287	0.0581	-0.0762	-0.3662	-0.0719	0.4113	0.157	1.1508	-0	0.0843	1.1155	0.4028	0.8771	234.499	61.0228	178.9125
132	0.5838	0.1308	-0.2074	0.9561	-0.1173	0.4261	-0.0034	-0.0709	-0.1134	0.0091	0.0464	-0.1343	0.0471	-0.0255	-0.0384	0.4963	-0.0271	0.0738	0.4657	0.0475	0.4092	111.4584	-3.9601	300.1317
133	0.2236	-0.3447	-0.2258	0.5675	0.5622	0.7037	-0.0378	0.1086	-0.0814	0.0478	0.0262	0.1921	0.1129	-0.0055	0.0261	0.704	-0.0636	-0.1631	0.3954	0.0747	0.712	122.7481	-48.0689	272.8455
134	0.2324	-0.0807	-0.1154	0.7345	-0.0663	1.8062	0.0198	0.2377	0.0907	-0.1805	-0.0511	0.0296	-0.1296	-0.429	-0.1717	1.5047	-0.0281	-0.0922	1.2143	0.5892	0.6543	160.171	85.9242	172.9002
135	0.8454	-0.0844	0.2423	1.2514	0.0558	0.4681	-0.0458	-0.1351	0.1347	0.2686	0.034	-0.2276	0.0451	0.0489	0.0091	0.6165	-0.0267	-0.0012	0.3537	0.1288	0.6474	176.8164	51.7734	253.4739
136	0.1816	0.384	0.1567	0.8703	0.3644	0.268	-0.2	-0.1134	0.1043	-0.0858	0.1422	-0.0852	-0.2002	0.2966	0.0368	0.9071	0.0031	-0.0592	0.752	0.0841	0.8689	189.874	100.6399	249.9078
137	0.6033	0.0234	0.1695	0.1851	0.0917	0.5028	-0.1044	0.3838	0.0616	-0.2904	-0.0846	0.034	0.2291	-0.1274	0.2167	1.7505	0.1279	-0.2251	1.1846	-0.0066	0.4962	140.0447	17.3744	151.1033
138	0.5287	-0.2557	-0.1847	0.6369	-0.1221	0.2113	0.1474	0.3572	-0.1444	-0.0059	0.1692	0.0255	0.1216	-0.1869	-0.2688	1.241	0.0778	-0.5671	1.2127	0.0571	0.9498	87.032	4.6842	170.3202
139	0.6657	-0.0914	0.0235	0.4658	-0.2151	1.1853	0.1209	0.0959	0.2483	-0.1969	0.2213	-0.0896	-0.3404	0.1648	-0.2371	1.6288	-0.0034	0.2124	1.6393	0.0107	0.5008	205.6085	19.0612	134.3065
140	0.2205	-0.1896	0.0523	0.5111	0.0279	0.311	0.1076	0.176	-0.1757	-0.3318	0.0035	0.1491	0.0721	0.005	-0.1333	1.0146	-0.0754	-0.2077	0.6702	-0.1325	0.6876	115.0629	-54.9767	215.5003
141	0.0517	-0.0743	-0.0969	2.4325	-0.3514	0.4357	0.1425	0.2796	-0.1708	-0.1371	-0.0536	0.4907	0.1513	0.2059	-0.106	0.703	0.0381	-0.3425	0.7086	-0.0927	1.1217	117.8235	-52.5151	249.7639
142	0.9467	0.501	-0.0489	0.8209	0.2247	1.6385	0.1064	0.0102	-0.1934	-0.1968	-0.0718	-0.3136	0.0111	0.398	0.0392	1.2252	0.3881	0.2938	1.4177	0.0545	0.5711	225.4772	18.9872	161.0466
143	1.8298	-0.5434	-0.3162	2.5156	-0.0866	1.6081	-0.0501	0.3327	0.2242	-0.2845	0.0771	0.1759	-0.1874	-0.178	-0.0686	0.7659	0.0131	0.084	0.7203	0.1931	0.4951	133.2007	71.6809	206.9123
144	1.0059	0.0133	0.3393	0.6401	0.1196	0.8884	-0.082	0.0011	0.1826	0.1224	0.0999	0.1724	-0.2606	-0.3894	0.0064	0.591	0.0202	-0.2155	0.5979	0.0783	0.7284	85.4369	0.4314	228.7986
145	1.6224	-0.1522	-0.4635	1.4592	0.1979	1.5445	0.0634	0.2083	0.1776	-0.1878	0.0251	0.2305	-0.2299	-0.3452	-0.1709	0.4319	0.017	0.0218	0.5436	0.0725	0.5581	85.1052	19.5768	263.1684
146	0.5666	0.0696	-0.2326	0.0675	0.1384	0.3937	-0.0002	0.3024	-0.1708	-0.2444	0.0585	0.1664	-0.0875	-0.2403	-0.0475	1.2457	0.0725	0.1573	1.041	0.1088	0.5517	185.4804	21.9527	159.7061
147	0.2287	0.2998	0.0706	0.6104	-0.0166	0.27	0.0725	0.145	-0.1814	-0.1463	0.229	0.0821	0.4808	-0.0426	-0.2945	1.4336	-0.1841	-0.4861	1.3516	0.1029	0.8224	120.3997	-9.2169	151.0458
148	0.7885	0.3039	-0.265	0.1608	-0.0885	0.4641	0.1028	0.1087	-0.2621	-0.2102	0.0266	0.0627	0.3945	0.2291	-0.0861	1.476	0.1277	-0.1422	0.857	-0.519	0.8587	154.4458	-67.9417	181.2621
149	0.5174	0.1732	-0.442	1.1013	0.3102	0.9171	-0.132	0.3007	-0.0743	-0.0438	-0.1602	0.0234	-0.3335	-0.2518	0.3356	1.1738	0.0949	-0.0319	0.7557	0.0631	0.5019	134.2776	-1.9842	178.2106
150	0.6295	0.1596	-0.1076	0.8597	0.3466	0.4645	0.0877	0.1576	0.2346	-0.0863	0	-0.1573	-0.099	-0.0566	-0.1036	1.8599	0.0534	0.2227	1.4568	0.2337	0.5923	164.6461	53.3984	139.939
151	0.5743	0.3394	-0.0206	0.5092	-0.0098	0.4853	0.0365	-0.0861	0.0663	-0.2658	-0.092	0.074	-0.1524	-0.0461	-0.0078	1.2682	0.0681	-0.1822	1.1337	0.1803	0.734	126.6992	19.4091	179.7215
152	1.65	-0.023	-0.0686	2.055	0.3752	1.9493	-0.2334	-0.2352	-0.1148	0.2547	-0.1798	0.1692	0.0116	-0.0167	0.4411	0.634	-0.0765	0.0071	0.4438	-0.0311	0.2858	152.8215	28.3545	297.2874
153	0.2581	-0.4103	-0.2958	1.8035	0.4782	1.1488	-0.0858	0.2545	0.0419	-0.1369	0.0086	0.1696	0.115	-0.1304	0.099	0.7369	-0.07	0.2824	0.8052	0.1323	0.944	212.7417	9.8292	229.8396
154	0.3485	-0.1454	0.1289	1.4677	-0.929	1.5765	-0.134	0.1528	-0.16	-0.1293	0.0777	-0.2971	0.2501	0.2516	0.0379	1.0277	0.1613	-0.1032	0.6271	-0.1834	0.8248	158.2765	-58.7793	233.1424
155	0.4759	-0.0574	-0.218	0.2468	0.2507	1.0524	0.3644	0.4184	0.0339	-0.3229	-0.2628	-0.0925	-0.2993	0.3909	-0.0047	0.9841	0.1721	0.0759	1.0132	0.0257	0.5154	204.2168	12.4478	186.7381
156	1.4705	0.1386	-0.141	0.8534	-0.3745	0.7719	0.0306	-0.4427	0.2854	0.2578	-0.335	-0.0655	-0.0789	-0.0077	0.3244	1.6694	-0.301	-0.1752	1.2024	-0.0505	1.1002	133.6736	15.3358	351.3034
157	0.6907	-0.3677	0.2722	1.5095	0.9735	1.0657	0.0444	-0.0674	0.0492	0.0857	-0.007	-0.0662	0.0627	0.0445	-0.0105	2.429	0.0236	0.154	2.4579	0.1238	2.3812	117.106	15.7556	370.3719
158	0.3323	-0.0255	0.008	0.3616	0.2188	0.1358	-0.0189	0.1519	0.0694	-0.1291	0.0577	0.0991	-0.0256	-0.0254	-0.0182	2.7571	0.221	0.9334	2.8174	0.0836	2.5175	102.2692	12.7033	379.2325
159	0.2592	0.0449	-0.0414	0.1681	-0.0163	0.1671	0.0691	-0.1088	0.0176	0.0954	-0.0802	-0.0207	-0.009	-0.0108	0.0089	0.4781	-0.1129	0.0117	0.5631	-0.0162	0.5813	39.0274	2.2325	76.1216
160	1.0513	0.1487	-0.285	0.0161	-0.0354	0.0982	-0.0179	0.0253	-0.4234	-0.0045	0.1686	0.9078	0.2982	-0.5921	-0.1397	1.4663	-0.3689	-0.1948	1.7076	-0.301	1.7603	-17.3896	-48.0676	14.7586
161	0.4128	0.0151	0.4691	0.5214	0.0655	0.5245	-0.3227	0.171	-0.1531	-0.1109	0.1894	0.9647	-0.1211	-0.7629	0.1879	1.643	0.1397	-0.1862	2.1386	0.0804	1.7154	-1.9878	0.2754	-24.7502
162	1.3838	-0.3935	-0.7001	1.3159	-0.4627	0.746	-0.0968	-0.5193	0.4437	1.0027	-0.0374	-0.4048	-0.388	0.1293	0.1473	1.4539	-0.2578	-0.0464	1.4774	0.0425	1.0232	27.2433	0.8414	156.1642
163	0.1979	-0.0918	0.0786	0.5798	-0.3365	0.42	0.0766	0.0579	-0.0057	-0.067	-0.0997	0.2578	0.1371	0.0381	0.0095	1.0583	-0.085	0.209	1.1237	-0.305	1.2436	-30.3665	-15.4446	61.2647
164	0.4921	-0.2751	0.5669	1.2326	0.3472	1.0661	-0.0227	-0.1484	-0.5053	-0.0606	0.1259	0.8494	0.7897	-0.8185	-0.0836	2.7375	-0.5013	-0.0567	2.6099	-0.2596	2.501	-22.5409	-27.3707	163.2987
165	2.1048	-1.0565	-0.5857	1.9863	-0.6434	2.8882	-0.1082	-0.5037	0.3565	0.5317	-0.0369	-0.6081	-0.3376	0.4866	0.101	2.1121	-0.2905	0.0456	1.9773	-0.0531	1.3852	10.9063	-2.396	182.4749
166	0.4296	-0.1526	-0.0908	1.745	1.0872	1.5315	0.3116	-0.8092	0.6493	0.6662	0.4728	-0.0727	-0.6686	-0.0083	-0.6285	1.4084	-0.0407	0.2891	1.4293	-0.3169	2.0464	-5.2317	88.9462	101.1893
167	0.4637	0.2711	0.3245	0.9035	0.1682	0.3528	0.0531	0.3735	-0.3812	-0.3945	0.099	0.0228	0.2996	0.0152	-0.1408	0.7917	-0.1783	-0.0442	0.9176	-0.2908	0.9317	23.6453	-66.3752	16.8221
168	0.2603	0.0285	0.0114	0.1471	-0.0607	0.6631	0.1075	-0.392	0.0142	0.2881	-0.1206	-0.0926	-0.1221	0.1664	0.0089	0.8327	-0.2869	-0.0634	1.0644	-0.041	0.6514	62.5993	7.7017	126.9188
169	0.4552	0.1257	-0.1194	0.7537	-0.0474	0.371	-0.0146	0.0455	0.3283	-0.2001	-0.0448	0.4554	-0.291	-0.2115	0.0656	0.8024	0.1837	-0.1554	0.9415	-0.1448	1.1367	-54.5275	63.9897	62.7726
170	1.9126	0.8208	-1.4519	4.8328	2.5284	3.3201	-0.1232	0.5591	0.6867	-0.8481	-0.1966	0.8839	-0.7998	-0.7972	0.2209	2.0148	0.4726	-0.3115	1.5882	-0.014	1.537	-49.2257	102.6546	34.5129
171	0.0503	0.0539	0.0573	2.7738	1.5178	0.8428	0.0234	-0.2621	0.3392	0.2839	-0.0222	0.1695	-0.3762	-0.2631	0.0071	1.7497	0.4614	0.2325	1.676	-0.2617	2.3222	-42.8542	128.2206	104.5285
172	1.0285	0.1312	0.0298	0.4295	-0.4926	0.6128	0.0115	0.0051	0.3969	0.4021	0.0871	0.0257	-0.2457	-0.0278	-0.1113	2.204	-0.2771	0.2731	2.242	-0.6816	2.1957	-59.7334	113.6536	118.6457
173	1.2146	-0.2138	-0.0646	0.4389	0.3349	0.3586	-0.5431	0.0386	-0.1818	0.1203	-0.1779	0.3949	0.2421	-0.1251	0.4546	3.0796	-0.1158	-0.6838	2.9067	-0.4356	2.7104	-112.4705	15.5674	26.7892
174	0.3463	-0.0541	-0.1871	0.7376	-0.3281	0.2747	0.0771	0.1227	-0.0957	-0.6136	0.1832	0.4728	0.1752	-0.6799	-0.3315	1.4161	0.3006	-0.514	1.7841	-0.0527	1.7297	-83.6562	49.6339	24.1732
175	0.6766	0.1958	0.0974	0.9642	0.3843	0.655	0.2272	-0.3498	0.0109	0.6549	-0.2991	0.2955	0.2477	-0.4356	0.043	0.9136	-0.4141	0.2213	1.0968	-0.1948	0.9841	-61.3275	10.8328	105.8569
176	0.0932	0.1476	-0.3039	0.7104	0.1646	1.8593	0.2771	0.1138	0.3025	-0.2483	0.5558	0.2297	-0.6135	-0.3124	-0.546	1.8341	0.2464	0.3428	2.0223	-0.5543	2.6476	-109.4795	58.7147	96.3958
177	0.1794	-0.2808	0.0755	0.5301	-0.2552	0.5468	-0.1388	0.2283	0.0294	-0.2288	0.1921	0.8012	0.0513	-0.4132	-0.0038	2.6679	-0.2056	0.0177	2.3935	-0.1562	2.0768	-100.4083	79.9718	108.8381
178	0.2569	-0.0841	-0.3729	0.6316	-0.1416	0.6467	0.1696	-0.1333	0.1406	-0.1632	-0.0435	0.2274	-0.2393	0.2191	-0.1673	0.9914	0.1628	0.0661	1.6056	-0.4507	1.7464	-80.5112	57.2234	78.5617
179	0.1399	0.442	-0.1213	1.9508	-0.4926	0.1268	0.2475	0.0956	0.1495	0.0659	-0.2988	0.2306	-0.5361	-0.358	0.0386	1.8022	0.0532	0.3748	2.0659	-0.6936	1.9146	-64.2679	79.0527	127.309
180	0.1908	0.2726	-0.0163	0.6419	0.1568	0.1584	0.0667	0.1353	-0.1519	0.1398	-0.0981	0.207	0.1836	-0.2755	-0.025	0.7771	-0.3604	0.0629	1.3478	-0.4164	1.4412	-75.2334	-46.957	55.5053
181	0.2318	0.2973	0.148	0.9884	0.3187	0.1729	0.0903	0.0967	-0.1505	-0.0497	-0.1133	-0.0652	-0.0159	-0.2118	0.0487	0.6485	0.0701	0.0582	0.9984	-0.1764	1.003	-36.1761	25.0787	74.2057
182	0.1981	-0.0036	-0.0166	0.2084	-0.0351	0.1547	0.0525	0.1927	-0.0329	-0.2016	-0.0172	0.1052	0.0616	-0.0222	-0.0364	0.7247	0.07	-0.1031	0.5256	-0.0025	0.4177	138.0221	3.0776	222.0862
183	3.0556	-0.2694	-0.1573	1.2758	0.1144	1.1377	0.0513	-0.4298	-0.49	0.3792	0.3045	-1.2655	0.1672	1.4331	-0.3109	1.4091	0.0167	-0.2503	1.4255	-0.111	1.6153	182.2124	-36.6034	299.5678
184	0.2013	0.042	0.3634	0.5525	0.1657	0.6405	0.2779	0.2645	0.0459	-0.0152	-0.3602	-0.4236	-0.0695	0.0056	0.1043	1.485	-0.2361	-0.0362	1.0521	0.2158	0.8985	153.7822	21.6283	331.224
185	1.2459	-0.094	-0.1517	0.9651	0.2651	0.0837	-0.3321	1.0855	0.5576	-0.9595	-0.0074	0.1051	-0.3392	0.3975	0.2662	2.1551	-0.3322	-0.0377	2.009	-0.1228	0.8573	167.7673	-7.3256	146.9494
186	0.8721	0.0492	-0.1169	0.9537	0.1255	0.4805	0.1487	-0.2977	-0.1409	0.1405	-0.1728	-0.195	0.1947	-0.1186	-0.0354	1.144	0.0284	0.1262	0.9662	0.2355	0.8377	204.1118	-10.9634	249.839
187	2.7133	0.2176	-0.2287	1.2984	-0.1685	1.9382	0.1299	0.2996	-0.9487	-0.6572	-0.023	-0.3666	0.6846	0.4306	-0.0298	2.7322	0.3177	-0.2175	2.1746	-0.2845	2.0235	218.518	-35.1227	152.1506
188	2.0683	-0.0599	-0.6396	1.9173	0.6104	0.7875	-0.0552	0.5797	0.1693	-0.6403	-0.1375	0.4407	-0.1191	-0.2929	0.1048	2.5967	0.0258	-0.1305	1.6451	-0.1925	1.3055	189.6207	-13.1448	125.3694
189	0.0838	0.0788	0.0747	0.3715	-0.0178	0.0888	0.0792	0.6822	0.7841	-0.3934	-0.0336	0.0484	-0.6065	0.1039	-0.0857	1.5188	0.0394	0.2701	1.1142	0.5849	1.3993	185.3171	88.7236	197.4562
190	0.4548	-0.1193	0.1321	0.662	-0.3125	0.3482	-0.0835	-0.1875	-0.2485	0.4809	0.1638	0.2221	-0.0082	-0.1005	-0.0932	0.6967	0.0531	-0.0532	0.3752	-0.0119	0.4677	141.7751	-56.7664	291.9216
191	0.1402	-0.1345	-0.1172	0.1623	-0.0278	0.2027	0.1366	0.263	0.0079	-0.391	0.0862	0.1725	0.1448	0.0158	-0.0271	1.2601	0.0306	-0.3	1.1708	-0.0046	0.5165	126.2289	1.2886	167.07
192	0.3748	-0.2078	0.0209	0.7982	-0.0335	0.2203	-0.0142	0.0605	0.2746	0.0206	-0.0991	-0.4811	-0.1941	0.0829	0.1095	0.828	-0.082	0.0029	0.5764	0.1927	0.8697	225.5804	69.1329	249.1325
193	1.7639	-0.881	-0.9747	3.4106	-1.3319	1.6503	0.1128	-0.5962	0.6609	0.6972	-0.2206	-0.3809	-0.5346	0.599	0.1203	1.9975	-0.2911	-0.3434	0.7469	-0.1463	1.3317	213.3149	109.2943	273.7329
194	3.2606	-0.3318	0.1485	4.0059	0.5365	0.7462	0.0087	0.5102	0.5945	-0.3617	0.1342	-0.3026	-0.5918	0.2826	-0.0875	2.3775	-0.3386	-0.025	1.5034	0.389	2.3814	220.0549	131.8199	202.8546
195	1.5241	0.6272	0.4008	0.5282	0.4989	1.1468	-0.1872	0.0033	0.4204	-0.2453	-0.095	0.0193	-0.44	-0.1133	0.2061	2.6559	0.3785	0.4474	2.8017	0.3822	2.6605	240.079	118.1681	192.2622
196	1.2507	-1.3319	-0.0619	2.1236	-0.1914	0.4139	-0.297	0.1726	-0.0909	-0.3519	-0.3877	-0.2738	0.2745	0.2135	0.5477	2.1345	0.065	-0.5445	2.0068	-0.0536	1.8767	276.9735	25.4991	297.8215
197	0.2667	-0.1583	0.0669	0.8181	0.1282	0.1183	-0.0858	-0.2914	0.0652	0.4385	0.1546	-0.262	0.0377	0.2447	-0.0536	1.4415	-0.1167	-0.5856	1.1041	-0.0545	1.543	246.8087	57.8829	293.055
198	0.321	-0.222	0.0385	0.5152	0.0671	0.2228	0.0984	0.2217	0.0054	-0.2683	-0.2063	-0.3372	0.0078	0.0922	0.0857	0.9237	0.0954	0.2669	0.8152	0.2287	0.7974	242.2353	15.1375	210.6004
199	1.6576	0.177	0.3887	0.841	0.5224	1.5013	0.3006	-1.0592	-0.0763	0.6553	0.2665	-0.1873	-0.0209	0.5498	-0.4154	1.975	-0.235	0.2558	2.0639	0.4615	2.3128	289.7638	59.755	236.5164
200	1.3356	-0.3747	0.1435	1.6681	0.6265	0.7264	0.0937	0.9799	0.3285	-1.0697	0.3508	-0.5755	-0.3031	0.5891	-0.2083	2.8224	-0.239	0.2083	2.595	-0.1278	2.6637	270.6642	90.1331	187.5241
201	0.4502	-0.132	-0.3607	0.2471	0.2866	0.6355	0.0158	0.128	0.3461	-0.1176	-0.2941	-0.3993	-0.2514	0.0767	0.165	0.9351	-0.0993	0.2734	0.7737	0.3792	1.5359	254.2763	63.1605	239.2681
202	0.6134	-0.7342	-0.0476	0.8713	0.0548	-0.0081	0.1602	0.0165	0.5599	-0.0588	-0.0778	-0.2891	-0.2196	-0.1791	-0.018	1.812	0.0409	0.4394	1.4269	0.5338	1.4264	247.4206	83.6812	187.7725
203	-0.2168	0.1272	0.0247	1.0276	-0.4764	0.4051	0.0385	0.0031	0.0476	0.2913	0.0967	0.0533	-0.0609	-0.0028	-0.0208	0.6416	0.153	0.2557	0.6179	0.2744	0.8153	247.6842	-40.3651	264.7813
204	0.8879	-0.3348	0.037	0.5177	-0.0553	0.689	0.1357	-0.0234	0.2365	-0.1482	-0.2222	-0.1594	-0.3017	-0.0838	0.103	0.6266	-0.1068	0.1145	0.6677	0.134	0.4202	206.7454	49.509	235.5719

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth seq-ID	Auth asym-ID
1	X-RAY DIFFRACTION	1	segid S0A	0
2	X-RAY DIFFRACTION	2	segid S1A	0
3	X-RAY DIFFRACTION	3	segid S2A	0
4	X-RAY DIFFRACTION	4	segid S3A	0
5	X-RAY DIFFRACTION	5	segid S4A	0
6	X-RAY DIFFRACTION	6	segid S5A	0
7	X-RAY DIFFRACTION	7	segid S6A	0
8	X-RAY DIFFRACTION	8	segid S7A	0
9	X-RAY DIFFRACTION	9	segid S8A	0
10	X-RAY DIFFRACTION	10	segid S9A	0
11	X-RAY DIFFRACTION	11	segid S10A	1 - 96	0
12	X-RAY DIFFRACTION	12	segid S11A	2 - 156	1
13	X-RAY DIFFRACTION	13	segid S12A	20 - 143	2
14	X-RAY DIFFRACTION	14	segid S13A	2 - 151	3
15	X-RAY DIFFRACTION	15	segid S14A	11 - 137	4
16	X-RAY DIFFRACTION	16	segid S15A	8 - 131	5
17	X-RAY DIFFRACTION	17	segid S16A	3 - 143	6
18	X-RAY DIFFRACTION	18	segid S17A	2 - 126	7
19	X-RAY DIFFRACTION	19	segid S18A	2 - 146	8
20	X-RAY DIFFRACTION	20	segid S19A	2 - 144	9
21	X-RAY DIFFRACTION	21	segid S20A	15 - 121	0
22	X-RAY DIFFRACTION	22	segid S21A	1 - 87	1
23	X-RAY DIFFRACTION	23	segid S22A	2 - 130	2
24	X-RAY DIFFRACTION	24	segid S23A	2 - 145	3
25	X-RAY DIFFRACTION	25	segid S24A	2 - 135	4
26	X-RAY DIFFRACTION	26	segid S25A	36 - 105	5
27	X-RAY DIFFRACTION	27	segid S26A	2 - 500	6
28	X-RAY DIFFRACTION	28	segid S27A	2 - 101	7
29	X-RAY DIFFRACTION	29	segid S28A	5 - 67	8
30	X-RAY DIFFRACTION	30	segid S29A	4 - 99	9
31	X-RAY DIFFRACTION	31	segid S30A	2 - 61	0
32	X-RAY DIFFRACTION	32	segid S31A	82 - 501	1
33	X-RAY DIFFRACTION	33	segid SRKA	2 - 319	R
34	X-RAY DIFFRACTION	34	segid STMA	9 - 176	M
35	X-RAY DIFFRACTION	35	segid L2A	0
36	X-RAY DIFFRACTION	36	segid L3A	0
37	X-RAY DIFFRACTION	37	segid L4A	0
38	X-RAY DIFFRACTION	38	segid L5A	0
39	X-RAY DIFFRACTION	39	segid L6A	0
40	X-RAY DIFFRACTION	40	segid L7A	0
41	X-RAY DIFFRACTION	41	segid L8A	0
42	X-RAY DIFFRACTION	42	segid L9A	0
43	X-RAY DIFFRACTION	43	segid L10A	2 - 221	0
44	X-RAY DIFFRACTION	44	segid L11A	6 - 174	1
45	X-RAY DIFFRACTION	45	segid L13A	2 - 194	3
46	X-RAY DIFFRACTION	46	segid L14A	3 - 138	4
47	X-RAY DIFFRACTION	47	segid L15A	2 - 204	5
48	X-RAY DIFFRACTION	48	segid L16A	3 - 199	6
49	X-RAY DIFFRACTION	49	segid L17A	2 - 184	7
50	X-RAY DIFFRACTION	50	segid L18A	2 - 186	8
51	X-RAY DIFFRACTION	51	segid L19A and resid 2:73	2 - 73	9
52	X-RAY DIFFRACTION	52	segid L19A and resid 74:126	74 - 126	9
53	X-RAY DIFFRACTION	53	segid L19A and resid 127:183	127 - 183	9
54	X-RAY DIFFRACTION	54	segid L20A	1 - 172	0
55	X-RAY DIFFRACTION	55	segid L21A	2 - 160	1
56	X-RAY DIFFRACTION	56	segid L22A	9 - 108	2
57	X-RAY DIFFRACTION	57	segid L23A	2 - 137	3
58	X-RAY DIFFRACTION	58	segid L24A	1 - 98	4
59	X-RAY DIFFRACTION	59	segid L25A	22 - 142	5
60	X-RAY DIFFRACTION	60	segid L26A	2 - 127	6
61	X-RAY DIFFRACTION	61	segid L27A	2 - 136	7
62	X-RAY DIFFRACTION	62	segid L28A	2 - 149	8
63	X-RAY DIFFRACTION	63	segid L29A	2 - 59	9
64	X-RAY DIFFRACTION	64	segid L30A	9 - 105	0
65	X-RAY DIFFRACTION	65	segid L31A	4 - 112	1
66	X-RAY DIFFRACTION	66	segid L32A	2 - 128	2
67	X-RAY DIFFRACTION	67	segid L33A	2 - 107	3
68	X-RAY DIFFRACTION	68	segid L34A	2 - 113	4
69	X-RAY DIFFRACTION	69	segid L35A	2 - 120	5
70	X-RAY DIFFRACTION	70	segid L36A	2 - 100	6
71	X-RAY DIFFRACTION	71	segid L37A	2 - 100	7
72	X-RAY DIFFRACTION	72	segid L38A	2 - 78	8
73	X-RAY DIFFRACTION	73	segid L39A	2 - 51	9
74	X-RAY DIFFRACTION	74	segid L40A	77 - 500	0
75	X-RAY DIFFRACTION	75	segid L41A	1 - 25	1
76	X-RAY DIFFRACTION	76	segid L42A	2 - 501	2
77	X-RAY DIFFRACTION	77	segid L43A	2 - 501	3
78	X-RAY DIFFRACTION	78	segid S0B	0
79	X-RAY DIFFRACTION	79	segid S1B	0
80	X-RAY DIFFRACTION	80	segid S2B	0
81	X-RAY DIFFRACTION	81	segid S3B	0
82	X-RAY DIFFRACTION	82	segid S4B	0
83	X-RAY DIFFRACTION	83	segid S5B	0
84	X-RAY DIFFRACTION	84	segid S6B	0
85	X-RAY DIFFRACTION	85	segid S7B	0
86	X-RAY DIFFRACTION	86	segid S8B	0
87	X-RAY DIFFRACTION	87	segid S9B	0
88	X-RAY DIFFRACTION	88	segid S10B	1 - 98	0
89	X-RAY DIFFRACTION	89	segid S11B	2 - 147	1
90	X-RAY DIFFRACTION	90	segid S12B	20 - 143	2
91	X-RAY DIFFRACTION	91	segid S13B	2 - 151	3
92	X-RAY DIFFRACTION	92	segid S14B	10 - 137	4
93	X-RAY DIFFRACTION	93	segid S15B	4 - 138	5
94	X-RAY DIFFRACTION	94	segid S16B	2 - 143	6
95	X-RAY DIFFRACTION	95	segid S17B	2 - 122	7
96	X-RAY DIFFRACTION	96	segid S18B	2 - 146	8
97	X-RAY DIFFRACTION	97	segid S19B	2 - 144	9
98	X-RAY DIFFRACTION	98	segid S20B	12 - 121	0
99	X-RAY DIFFRACTION	99	segid S21B	1 - 87	1
100	X-RAY DIFFRACTION	100	segid S22B	2 - 130	2
101	X-RAY DIFFRACTION	101	segid S23B	2 - 145	3
102	X-RAY DIFFRACTION	102	segid S24B	2 - 135	4
103	X-RAY DIFFRACTION	103	segid S25B	37 - 105	5
104	X-RAY DIFFRACTION	104	segid S26B	2 - 500	6
105	X-RAY DIFFRACTION	105	segid S27B	2 - 1	7
106	X-RAY DIFFRACTION	106	segid S28B	5 - 67	8
107	X-RAY DIFFRACTION	107	segid S29B	4 - 99	9
108	X-RAY DIFFRACTION	108	segid S30B	2 - 63	0
109	X-RAY DIFFRACTION	109	segid S31B	77 - 501	1
110	X-RAY DIFFRACTION	110	segid SRKB	2 - 319	R
111	X-RAY DIFFRACTION	111	segid STMB	23 - 174	M
112	X-RAY DIFFRACTION	112	segid L2B	0
113	X-RAY DIFFRACTION	113	segid L3B	0
114	X-RAY DIFFRACTION	114	segid L4B	0
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