PDB-4u50: Crystal structure of Verrucarin bound to the yeast 80S ribosome

Basic information

• Entry: Database: PDB / ID: 4u50
• Title: Crystal structure of Verrucarin bound to the yeast 80S ribosome

Components

• (40S ribosomal protein ...) x 32
• (60S ribosomal protein ...) x 40
• (UNKNOWN PROTEIN ...) x 3
• 18S ribosomal RNA
• 25S ribosomal RNA
• 5.8S ribosomal RNA
• 5S ribosomal RNA
• 60S acidic ribosomal protein P0
• Guanine nucleotide-binding protein subunit beta-like protein
• Suppressor protein STM1
• Ubiquitin-40S ribosomal protein S31
• Ubiquitin-60S ribosomal protein L40

• Keywords: RIBOSOME / translation / 40S / 60S / 80S / eukaryote / RNA-protein complex / inhibitor / antibiotic

Function / homology

Function:

ribosome hibernation / triplex DNA binding / translation elongation factor binding / regulation of translational initiation in response to stress / Platelet degranulation / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / negative regulation of glucose mediated signaling pathway / negative regulation of translational frameshifting / Protein methylation / RMTs methylate histone arginines / positive regulation of translational fidelity / GDP-dissociation inhibitor activity / mTORC1-mediated signalling / ribosome-associated ubiquitin-dependent protein catabolic process / Protein hydroxylation / : / pre-mRNA 5'-splice site binding / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / Ribosomal scanning and start codon recognition / preribosome, small subunit precursor / translational elongation / response to cycloheximide / telomeric DNA binding / mRNA destabilization / TOR signaling / Major pathway of rRNA processing in the nucleolus and cytosol / SRP-dependent cotranslational protein targeting to membrane / 90S preribosome / GTP hydrolysis and joining of the 60S ribosomal subunit / Formation of a pool of free 40S subunits / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / : / negative regulation of mRNA splicing, via spliceosome / protein-RNA complex assembly / ribosomal small subunit export from nucleus / preribosome, large subunit precursor / L13a-mediated translational silencing of Ceruloplasmin expression / translation regulator activity / ribosomal large subunit export from nucleus / G-protein alpha-subunit binding / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / regulation of translational fidelity / positive regulation of protein kinase activity / rescue of stalled ribosome / translational termination / maturation of SSU-rRNA / translation repressor activity / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / ribosomal large subunit biogenesis / DNA-(apurinic or apyrimidinic site) endonuclease activity / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / cellular response to amino acid starvation / ribosome assembly / telomere maintenance / small-subunit processome / protein kinase C binding / maintenance of translational fidelity / macroautophagy / modification-dependent protein catabolic process / ribosomal small subunit biogenesis / protein tag activity / small ribosomal subunit rRNA binding / rRNA processing / ribosomal small subunit assembly / cytoplasmic stress granule / ribosomal large subunit assembly / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / ribosome binding / ribosome biogenesis / 5S rRNA binding / cytoplasmic translation / small ribosomal subunit / cytosolic large ribosomal subunit / negative regulation of translation / protein ubiquitination / rRNA binding / ribosome / structural constituent of ribosome / positive regulation of protein phosphorylation / translation / G protein-coupled receptor signaling pathway / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / nucleolus / negative regulation of apoptotic process / perinuclear region of cytoplasm / mitochondrion / DNA binding / RNA binding / zinc ion binding / nucleoplasm

Domain/homology:

Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / : / Ribosomal protein S12e / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Small (40S) ribosomal subunit Asc1/RACK1 / Insertion domain in 60S ribosomal protein L10P / : / S27a-like superfamily / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein S25 / Ribosomal protein S26e signature. / Ribosomal protein S17e, conserved site / : / Ribosomal protein S30 / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein S3, eukaryotic/archaeal / S25 ribosomal protein / Ribosomal protein L10e, conserved site / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein L10e / Ribosomal protein L27e, conserved site / Ribosomal protein S19A/S15e / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein S30 / Ribosomal protein S3Ae, conserved site / Ribosomal protein S12e signature. / Ribosomal protein S17e / Ribosomal protein S17e-like superfamily / Ribosomal protein S27a / 40S ribosomal protein S11, N-terminal / 40S ribosomal protein S1/3, eukaryotes / Ribosomal protein S6, eukaryotic / Ribosomal protein S7e / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein S19e, conserved site / Ribosomal S17 / Ribosomal protein S19e signature. / Ribosomal protein L44e / Ribosomal protein L38e / Ribosomal protein S2, eukaryotic / Ribosomal protein L38e superfamily / Ribosomal protein L27e / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein L27e superfamily / Ribosomal protein S21e / Ribosomal protein S27, zinc-binding domain superfamily / Ribosomal L38e protein family / Ribosomal protein L29e / Ribosomal L29e protein family / 60S ribosomal protein L35 / Ribosomal protein S17, archaeal/eukaryotic / Ribosomal protein S27 / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S28e conserved site / Ribosomal protein S6/S6e/A/B/2, conserved site / Ribosomal protein S28e / Ribosomal protein L35Ae, conserved site / 40S Ribosomal protein S10 / Ribosomal_S17 N-terminal / Ribosomal protein S3Ae / Ribosomal S3Ae family / Ribosomal protein L44 / Ribosomal protein S7e / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal L27e protein family / Ribosomal protein S5/S7, eukaryotic/archaeal / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein S6e / Plectin/S10, N-terminal / Ribosomal protein S13/S15, N-terminal / Ribosomal protein S15P / Plectin/S10 domain / Ribosomal S13/S15 N-terminal domain / Ribosomal protein S6e / Ribosomal protein S4/S9, eukaryotic/archaeal / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein L31e, conserved site / Ribosomal protein L37ae / Ribosomal protein S27 / Ribosomal protein L19, eukaryotic / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal S3Ae family / Ribosomal protein L35A / Ribosomal protein S17e signature.

Component:

Chem-3L2 / osmium (III) hexammine / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein uS11A / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Large ribosomal subunit protein eL18A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A

• Biological species: Saccharomyces cerevisiae S288c (yeast)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.2 Å
• Authors: Garreau de Loubresse, N. / Prokhorova, I. / Yusupova, G. / Yusupov, M.
• Citation: Journal: Nature / Year: 2014; Title: Structural basis for the inhibition of the eukaryotic ribosome.; Authors: Garreau de Loubresse, N. / Prokhorova, I. / Holtkamp, W. / Rodnina, M.V. / Yusupova, G. / Yusupov, M.

History

Deposition	Jul 24, 2014	Deposition site: RCSB / Processing site: PDBE
Revision 1.0	Oct 22, 2014	Provider: repository / Type: Initial release
Supersession	Dec 10, 2014	ID: 4ulp, 4ulq, 4ulr, 4uls, 4ult
Revision 1.1	Dec 10, 2014	Group: Other
Revision 1.2	Dec 17, 2014	Group: Other
Revision 1.3	Jan 21, 2015	Group: Derived calculations
Revision 1.4	Jan 20, 2016	Group: Structure summary
Revision 1.5	Jul 18, 2018	Group: Advisory / Data collection / Derived calculations / Source and taxonomy Category: database_PDB_caveat / entity_src_nat / pdbx_unobs_or_zero_occ_atoms / pdbx_validate_close_contact / struct_conn / struct_conn_type Item: _entity_src_nat.pdbx_organism_scientific
Revision 1.6	Dec 20, 2023	Group: Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id

Assembly

Deposited unit

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

m2: UNKNOWN PROTEIN m2

p1: UNKNOWN PROTEIN p1

p2: UNKNOWN PROTEIN p2

hetero molecules

Summary:

• 6.63 MDa, 162 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	6,631,808	2722
Polymers	6,271,321	162
Non-polymers	360,487	2560
Water	0

1

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

hetero molecules

Summary:

• defined by author
• 3.28 MDa, 79 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,284,669	1322
Polymers	3,107,945	79
Non-polymers	176,724	1243
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

m2: UNKNOWN PROTEIN m2

p1: UNKNOWN PROTEIN p1

p2: UNKNOWN PROTEIN p2

hetero molecules

Summary:

• defined by author
• 3.35 MDa, 83 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,347,139	1400
Polymers	3,163,376	83
Non-polymers	183,763	1317
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	434.390, 285.580, 303.060
Angle α, β, γ (deg.)	90.000, 98.990, 90.000
Int Tables number	4
Space group name H-M	P1211

• Details: there are 2 biological units in the asymetric unit (segid *A and segid *B)

Components

RNA chain , 4 types, 8 molecules 2 6 1 5 3 7 4 8

#1: RNA chain

2 6 18S ribosomal RNA / / RNA (1750-MER)

Details:

Mass: 579761.938 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: GenBank: 1262303

#36: RNA chain

1 5 25S ribosomal RNA /

Details:

Mass: 1097493.875 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: TPG: 329138943

#37: RNA chain

3 7 5S ribosomal RNA / / RNA (121-MER)

Details:

Mass: 38951.105 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: TPG: 329138943

#38: RNA chain

4 8 5.8S ribosomal RNA / / RNA (158-MER)

Details:

Mass: 50682.922 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: GenBank: 618731124

40S ribosomal protein ... , 32 types, 62 molecules S0 s0 S1 s1 S2 s2 S3 s3 S4 s4 S5 s5 S6 s6 S7 s7 S8 s8 S9 s9 C0 c0 C1 c1 C2 c2 C3 c3 C4 c4 ...

#2: Protein

S0 s0 40S ribosomal protein S0-A / Ribosome / Nucleic acid-binding protein NAB1A

Details:

Mass: 27920.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P32905

#3: Protein

S1 s1 40S ribosomal protein S1-A / Ribosome / RP10A

Details:

Mass: 28667.275 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P33442

#4: Protein

S2 s2 40S ribosomal protein S2 / / Omnipotent suppressor protein SUP44 / RP12 / S4 / YS5

Details:

Mass: 27359.629 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P25443

#5: Protein

S3 s3 40S ribosomal protein S3 / / RP13 / YS3

Details:

Mass: 26411.596 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05750

#6: Protein

S4 s4 40S ribosomal protein S4-A / Ribosome / RP5 / S7 / YS6

Details:

Mass: 29338.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX35

#7: Protein

S5 s5 40S ribosomal protein S5 / / RP14 / S2 / YS8

Details:

Mass: 24941.402 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P26783

#8: Protein

S6 s6 40S ribosomal protein S6-A / Ribosome / RP9 / S10 / YS4

Details:

Mass: 27054.486 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX37

#9: Protein

S7 s7 40S ribosomal protein S7-A / Ribosome / RP30 / RP40

Details:

Mass: 21527.014 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P26786

#10: Protein

S8 s8 40S ribosomal protein S8-A / Ribosome / RP19 / S14 / YS9

Details:

Mass: 22537.803 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX39

#11: Protein

S9 s9 40S ribosomal protein S9-A / Ribosome / RP21 / S13 / YP28 / YS11

Details:

Mass: 22356.695 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: O13516

#12: Protein

C0 c0 40S ribosomal protein S10-A / Ribosome

Details:

Mass: 12771.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q08745

#13: Protein

C1 c1 40S ribosomal protein S11-A / Ribosome / RP41 / S18 / YS12

Details:

Mass: 17668.766 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX47

#14: Protein

C2 c2 40S ribosomal protein S12 /

Details:

Mass: 15385.485 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P48589

#15: Protein

C3 c3 40S ribosomal protein S13 / / S27a / YS15

Details:

Mass: 16928.748 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05756

#16: Protein

C4 c4 40S ribosomal protein S14-A / Ribosome / RP59A

Details:

Mass: 14431.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P06367

#17: Protein

C5 c5 40S ribosomal protein S15 / / RIG protein / RP52 / S21 / YS21

Details:

Mass: 15830.597 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q01855

#18: Protein

C6 c6 40S ribosomal protein S16-A / Ribosome / RP61R

Details:

Mass: 15746.292 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX51

#19: Protein

C7 c7 40S ribosomal protein S17-A / Ribosome / RP51A

Details:

Mass: 15820.413 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P02407

#20: Protein

C8 c8 40S ribosomal protein S18-A / Ribosome

Details:

Mass: 16940.443 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX55

#21: Protein

C9 c9 40S ribosomal protein S19-A / Ribosome / RP55A / S16a / YP45 / YS16A

Details:

Mass: 15810.930 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P07280

#22: Protein

D0 d0 40S ribosomal protein S20 /

Details:

Mass: 13797.850 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P38701

#23: Protein

D1 d1 40S ribosomal protein S21-A / Ribosome / S26 / YS25

Details:

Mass: 9758.829 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0C0V8

#24: Protein

D2 d2 40S ribosomal protein S22-A / Ribosome / RP50 / S24 / YP58 / YS22

Details:

Mass: 14518.867 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0C0W1

#25: Protein

D3 d3 40S ribosomal protein S23-A / Ribosome / RP37 / S28 / YS14

Details:

Mass: 15942.699 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX29

#26: Protein

D4 d4 40S ribosomal protein S24-A / Ribosome / RP50

Details:

Mass: 15231.650 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX31

#27: Protein

D5 d5 40S ribosomal protein S25-A / Ribosome / RP45 / S31 / YS23

Details:

Mass: 11936.076 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q3E792

#28: Protein

D6 d6 40S ribosomal protein S26-B / Ribosome

Details:

Mass: 11022.989 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P39939

#29: Protein

D7 d7 40S ribosomal protein S27-A / Ribosome / RP61 / YS20

Details:

Mass: 8762.195 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P35997

#30: Protein

D8 d8 40S ribosomal protein S28-A / Ribosome / S33 / YS27

Details:

Mass: 7474.652 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q3E7X9

#31: Protein

D9 d9 40S ribosomal protein S29-A / Ribosome / S36 / YS29

Details:

Mass: 6544.527 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P41057

#32: Protein

E0 40S ribosomal protein S30-A / Ribosome

Details:

Mass: 6779.086 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX33

#80: Protein

e0 40S ribosomal protein S30-A / Ribosome

Details:

Mass: 7006.346 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX33

Protein , 5 types, 9 molecules E1 e1 SR sR SM sM Q0 q0 p0

#33: Protein

E1 e1 Ubiquitin-40S ribosomal protein S31

Details:

Mass: 8717.488 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05759

#34: Protein

SR sR Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1

Details:

Mass: 34710.023 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P38011

#35: Protein

SM sM Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1

Details:

Mass: 30048.010 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P39015

#76: Protein

Q0 q0 Ubiquitin-60S ribosomal protein L40

Details:

Mass: 6032.321 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CH08

#81: Protein

p0 60S acidic ribosomal protein P0 / / A0 / L10E

Details:

Mass: 33617.930 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05317

60S ribosomal protein ... , 40 types, 80 molecules L2 l2 L3 l3 L4 l4 L5 l5 L6 l6 L7 l7 L8 l8 L9 l9 M0 m0 M1 m1 M3 m3 M4 m4 M5 m5 M6 m6 M7 m7 ...

#39: Protein

L2 l2 60S ribosomal protein L2-A / Ribosome / L5 / RP8 / YL6

Details:

Mass: 27332.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX45

#40: Protein

L3 l3 60S ribosomal protein L3 / / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1

Details:

Mass: 43719.602 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P14126

#41: Protein

L4 l4 60S ribosomal protein L4-A / Ribosome / L2 / RP2 / YL2

Details:

Mass: 39027.926 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P10664

#42: Protein

L5 l5 60S ribosomal protein L5 / / L1 / L1a / Ribosomal 5S RNA-binding protein / YL3

Details:

Mass: 33633.633 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P26321

#43: Protein

L6 l6 60S ribosomal protein L6-A / Ribosome / L17 / RP18 / YL16

Details:

Mass: 19869.369 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q02326

#44: Protein

L7 l7 60S ribosomal protein L7-A / Ribosome / L6 / RP11 / YL8

Details:

Mass: 27555.084 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05737

#45: Protein

L8 l8 60S ribosomal protein L8-A / Ribosome / L4 / L4-2 / L7a-1 / Maintenance of killer protein 7 / RP6 / YL5

Details:

Mass: 28044.621 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P17076

#46: Protein

L9 l9 60S ribosomal protein L9-A / Ribosome / L8 / RP24 / YL11

Details:

Mass: 21605.061 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05738

#47: Protein

M0 m0 60S ribosomal protein L10 / / L9 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein

Details:

Mass: 25279.271 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P41805

#48: Protein

M1 m1 60S ribosomal protein L11-B / Ribosome / L16 / RP39 / YL22

Details:

Mass: 19654.520 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q3E757

#49: Protein

M3 m3 60S ribosomal protein L13-A / Ribosome

Details:

Mass: 22472.967 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q12690

#50: Protein

M4 m4 60S ribosomal protein L14-A / Ribosome

Details:

Mass: 15063.870 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P36105

#51: Protein

M5 m5 60S ribosomal protein L15-A / Ribosome / L13 / RP15R / YL10 / YP18

Details:

Mass: 24351.162 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05748

#52: Protein

M6 m6 60S ribosomal protein L16-A / Ribosome / L13a / L21 / RP22 / YL15

Details:

Mass: 22116.029 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P26784

#53: Protein

M7 m7 60S ribosomal protein L17-A / Ribosome / L20A / YL17

Details:

Mass: 20458.322 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05740

#54: Protein

M8 m8 60S ribosomal protein L18-A / Ribosome / RP28

Details:

Mass: 20478.059 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX49

#55: Protein

M9 m9 60S ribosomal protein L19-A / Ribosome / L23 / RP15L / RP33 / YL14

Details:

Mass: 21631.121 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX82

#56: Protein

N0 n0 60S ribosomal protein L20-A / Ribosome / L18a

Details:

Mass: 20478.852 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX23

#57: Protein

N1 n1 60S ribosomal protein L21-A / Ribosome

Details:

Mass: 18148.066 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: Q02753

#58: Protein

N2 n2 60S ribosomal protein L22-A / Ribosome / L1c / RP4 / YL31

Details:

Mass: 13580.163 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05749

#59: Protein

N3 n3 60S ribosomal protein L23-A / Ribosome / L17a / YL32

Details:

Mass: 14362.755 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX41

#60: Protein

N4 n4 60S ribosomal protein L24-A / Ribosome / L30 / RP29 / YL21

Details:

Mass: 17661.717 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P04449

#61: Protein

N5 n5 60S ribosomal protein L25 / / RP16L / YL25 / YP42'

Details:

Mass: 15656.417 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P04456

#62: Protein

N6 n6 60S ribosomal protein L26-A / Ribosome / L33 / YL33

Details:

Mass: 14134.588 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05743

#63: Protein

N7 n7 60S ribosomal protein L27-A / Ribosome

Details:

Mass: 15437.166 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0C2H6

#64: Protein

N8 n8 60S ribosomal protein L28 / / L27a / L29 / RP44 / RP62 / YL24

Details:

Mass: 16630.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P02406

#65: Protein

N9 n9 60S ribosomal protein L29 / / YL43

Details:

Mass: 6560.688 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05747

#66: Protein

O0 o0 60S ribosomal protein L30 / / L32 / RP73 / YL38

Details:

Mass: 11299.168 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P14120

#67: Protein

O1 o1 60S ribosomal protein L31-A / Ribosome / L34 / YL28

Details:

Mass: 12848.962 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0C2H8

#68: Protein

O2 o2 60S ribosomal protein L32 /

Details:

Mass: 14678.246 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P38061

#69: Protein

O3 o3 60S ribosomal protein L33-A / Ribosome / L37 / RP47 / YL37

Details:

Mass: 12045.935 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05744

#70: Protein

O4 o4 60S ribosomal protein L34-A / Ribosome

Details:

Mass: 13542.001 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P87262

#71: Protein

O5 o5 60S ribosomal protein L35-A / Ribosome

Details:

Mass: 13811.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX84

#72: Protein

O6 o6 60S ribosomal protein L36-A / Ribosome / L39 / YL39

Details:

Mass: 11020.063 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P05745

#73: Protein

O7 o7 60S ribosomal protein L37-A / Ribosome / L43 / YL35 / YP55

Details:

Mass: 9746.199 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P49166

#74: Protein

O8 o8 60S ribosomal protein L38 /

Details:

Mass: 8714.363 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P49167

#75: Protein/peptide

O9 o9 60S ribosomal protein L39 / / L46 / YL40

Details:

Mass: 6227.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P04650

#77: Protein/peptide

Q1 q1 60S ribosomal protein L41-A / Ribosome

Details:

Mass: 3354.243 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast)

#78: Protein

Q2 q2 60S ribosomal protein L42-A / Ribosome / L41 / YL27 / YP44

Details:

Mass: 12115.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX27

#79: Protein

Q3 q3 60S ribosomal protein L43-A / Ribosome / L37a / YL35

Details:

Mass: 9981.756 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast) / References: UniProt: P0CX25

UNKNOWN PROTEIN ... , 3 types, 3 molecules m2 p1 p2

#82: Protein

m2 UNKNOWN PROTEIN m2

Details:

Mass: 13634.798 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast)

#83: Protein/peptide

p1 UNKNOWN PROTEIN p1

Details:

Mass: 4017.944 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast)

#84: Protein/peptide

p2 UNKNOWN PROTEIN p2

Details:

Mass: 3932.839 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Saccharomyces cerevisiae S288c (yeast)

Non-polymers , 4 types, 2560 molecules

#85: Chemical

2-1901 2-1902 2-1903 2-1904 2-1905 2-1906 2-1907 2-1908 2-1909 2-1910 2-1911 2-1912 2-1913 2-1914 2-1915 2-1916 2-1917 2-1918 2-1919 2-1920 ...
ChemComp-MG / MAGNESIUM ION

Details:

Mass: 24.305 Da / Num. of mol.: 1410 / Source method: obtained synthetically / Formula: Mg

#86: Chemical

2-2022 2-2023 2-2024 2-2025 2-2026 2-2027 2-2028 2-2029 2-2030 2-2031 2-2032 2-2033 2-2034 2-2035 2-2036 2-2037 2-2038 2-2039 2-2040 2-2041 ...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide

Details:

Mass: 286.365 Da / Num. of mol.: 1132 / Source method: obtained synthetically / Formula: H₁₂N₆Os

#87: Chemical

D6-500 D7-101 D9-101 E1-501 O7-101 Q0-500 Q2-501 Q3-501 d6-101 d7-101 d9-101 e1-501 o7-501 q0-201 q2-501 q3-501
ChemComp-ZN / ZINC ION

Details:

Mass: 65.409 Da / Num. of mol.: 16 / Source method: obtained synthetically / Formula: Zn

#88: Chemical

1-4212 5-4246 ChemComp-3L2 / (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione / Verrucarin A / Verrucarin A

Details:

Mass: 502.553 Da / Num. of mol.: 2 / Source method: obtained synthetically / Formula: C₂₇H₃₄O₉ / Comment: toxin*YM

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 3.02 ų/Da / Density % sol: 59.3 %
• Crystal grow: Temperature: 277 K / Method: vapor diffusion, hanging drop / pH: 7.5 ; Details: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: SOLEIL / Beamline: PROXIMA 1 / Wavelength: 1 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Jul 1, 2013
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 1 Å / Relative weight: 1
• Reflection: Resolution: 3.2→49.88 Å / Num. obs: 1195096 / % possible obs: 99.9 % / Observed criterion σ(I): -3 / Redundancy: 4.11 % / B_iso Wilson estimate: 72.42 Ų / R_merge F obs: 0.967 / R_merge(I) obs: 0.345 / R_rim(I) all: 0.395 / Χ²: 0.925 / Net I/σ(I): 5.59 / Num. measured all: 4861213

Reflection shell

Diffraction-ID: 1 / Rejects: 0

Resolution (Å)	Highest resolution (Å)	Rmerge F obs	Rmerge(I) obs	Mean I/σ(I) obs	Num. measured obs	Num. possible	Num. unique obs	Rrim(I) all	% possible all
3.2-3.3		0.28	2.237	0.95	432366	105265	105110	2.554	99.9
3.3-3.4		0.363	1.658	1.2	368042	93322	93200	1.908	99.9
3.4-3.5		0.486	1.283	1.53	342628	82836	82762	1.466	99.9
3.5-4		0.741	0.74	2.64	1226531	301318	301106	0.846	99.9
4-5		0.935	0.311	5.69	1213829	298907	298667	0.355	99.9
5-10		0.985	0.137	10.73	1123734	275239	275041	0.156	99.9
10-20		0.996	0.052	21.84	136664	34806	34666	0.06	99.6
20-30		0.998	0.034	30.59	13944	3563	3520	0.04	98.8
30-40		0.997	0.032	32.75	2981	881	811	0.038	92.1
40-50		0.997	0.035	14.59	494	323	213	0.045	65.9
	50					349

Processing

Software

Name	Version	Classification
XDS		data reduction
PHENIX	(phenix.refine: dev_1702)	refinement
PDB_EXTRACT	3.14	data extraction
XSCALE		data scaling
XSCALE		data reduction

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 3U5B, 3U5C, 3U5D, 3U5E, 3U5F, 3U5G, 3U5H, 3U5I

3u5b
PDB Unreleased entry

3u5c
PDB Unreleased entry

3u5d
PDB Unreleased entry

3u5e
PDB Unreleased entry

3u5f
PDB Unreleased entry

3u5g
PDB Unreleased entry

3u5h
PDB Unreleased entry

3u5i
PDB Unreleased entry

Resolution: 3.2→49.88 Å / SU ML: 0.44 / Cross valid method: FREE R-VALUE / σ(F): 0 / Phase error: 25.76 / Stereochemistry target values: ML

	Rfactor	Num. reflection	% reflection
Rfree	0.2619	23895	2 %
Rwork	0.2122	1170845	-
obs	0.2132	1194740	99.86 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso max: 273.29 Ų / B_iso mean: 65.147 Ų / B_iso min: 10.72 Ų

Refinement step

Cycle: final / Resolution: 3.2→49.88 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	179692	222116	11002	0	412810
Biso mean	-	-	111.26	-	-
Num. residues	-	-	-	-	32990

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.011	438213
X-RAY DIFFRACTION	f_angle_d	1.546	650261
X-RAY DIFFRACTION	f_chiral_restr	0.061	79434
X-RAY DIFFRACTION	f_plane_restr	0.007	41796
X-RAY DIFFRACTION	f_dihedral_angle_d	19.015	194820

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection all	% reflection obs (%)
3.2-3.2363	0.3457	794	0.3082	38880	39674	100
3.2363-3.2744	0.3572	793	0.304	38894	39687	100
3.2744-3.3143	0.3389	795	0.291	38984	39779	100
3.3143-3.3563	0.3114	794	0.2748	38935	39729	100
3.3563-3.4004	0.3223	795	0.2728	38934	39729	100
3.4004-3.447	0.3181	795	0.2702	38944	39739	100
3.447-3.4962	0.308	793	0.2614	38899	39692	100
3.4962-3.5484	0.3118	795	0.254	38952	39747	100
3.5484-3.6038	0.2916	796	0.2375	38990	39786	100
3.6038-3.6629	0.2844	796	0.2335	38965	39761	100
3.6629-3.7261	0.2931	794	0.2288	38958	39752	100
3.7261-3.7938	0.2823	798	0.224	39049	39847	100
3.7938-3.8667	0.2706	795	0.2113	38957	39752	100
3.8667-3.9456	0.2562	796	0.1992	39023	39819	100
3.9456-4.0314	0.2551	795	0.1961	38959	39754	100
4.0314-4.1251	0.2392	796	0.1895	39011	39807	100
4.1251-4.2282	0.253	795	0.191	38969	39764	100
4.2282-4.3425	0.2298	797	0.1813	39037	39834	100
4.3425-4.4702	0.2295	797	0.1794	39045	39842	100
4.4702-4.6144	0.2461	797	0.183	39062	39859	100
4.6144-4.7792	0.2365	796	0.1778	38995	39791	100
4.7792-4.9704	0.2357	798	0.1828	39122	39920	100
4.9704-5.1963	0.2243	798	0.1735	39115	39913	100
5.1963-5.47	0.2221	798	0.1766	39061	39859	100
5.47-5.8122	0.2325	797	0.1841	39079	39876	100
5.8122-6.2602	0.2471	800	0.1902	39160	39960	100
6.2602-6.8887	0.2662	800	0.2053	39218	40018	100
6.8887-7.8822	0.2565	800	0.2072	39225	40025	100
7.8822-9.9179	0.2608	802	0.2218	39286	40088	100
9.9179-49.8953	0.2498	800	0.2349	39137	39937	98

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.6165	-0.0877	-0.5314	0.2728	0.0786	0.9021	0.0579	-0.1043	-0.1809	0.2432	-0.0947	0.0582	0.1265	0.0368	0.0155	0.635	-0.3847	0.4748	1.0502	-0.3235	1.0857	-110.4713	-8.0194	109.7736
2	0.4387	-0.4056	0.1261	0.6339	-0.0525	0.2676	-0.0543	-0.2607	-0.3319	0.4582	-0.1072	-0.0721	0.2663	-0.0159	0.0741	1.3607	-0.2076	0.0827	0.8656	0.2977	0.837	-46.9518	-27.6868	138.6665
3	0.5638	0.054	-0.2839	0.3697	0.102	0.6641	-0.0055	-0.0704	0.1075	0.13	0.0446	0.2931	0.0388	-0.3568	-0.0865	0.3878	-0.0679	0.0474	0.9998	-0.3127	0.9438	-100.8253	9.7318	76.5677
4	0.3969	0.2388	0.0379	0.3932	-0.0936	0.167	0.0411	0.0418	0.0577	0.021	-0.0176	0.2018	0.0522	-0.1029	-0.0391	0.5056	-0.1567	-0.0339	1.126	-0.3741	0.9654	-99.3645	-28.9593	45.6583
5	0.2764	-0.0846	-0.1704	0.3771	0.0552	0.4873	-0.0154	-0.0328	0.1577	0.0875	-0.0249	0.269	-0.0504	-0.2533	0.0467	0.6331	0.3207	0.0364	0.878	-0.0514	0.9419	-79.6885	81.0399	70.8688
6	0.3744	-0.2884	0.2056	0.2996	0.0904	0.9222	-0.0705	-0.2028	-0.147	0.0808	0.0205	-0.0224	0.3008	-0.0395	-0.0324	1.1057	-0.3048	0.0355	0.6573	-0.1583	0.7491	-76.3836	-76.7694	90.5285
7	0.2648	-0.0333	-0.187	0.4272	-0.0653	0.3834	-0.0542	0.1451	0.2056	-0.2681	-0.0955	0.0051	-0.2346	-0.1179	0.1445	0.8432	0.2494	-0.0297	0.6981	0.1595	0.8808	-29.9037	97.8909	48.5335
8	0.5607	-0.0962	-0.1752	0.4865	0.1144	0.5925	0.0163	-0.2626	0.1708	0.2244	-0.0562	0.0357	-0.205	-0.1619	-0.2207	0.8204	0.012	0.5861	1.0686	-0.3801	0.8757	-97.4554	47.976	135.8714
9	0.321	0.02	-0.0682	0.9817	0.2709	0.4314	0.0753	-0.1098	0.2375	0.1938	-0.063	0.0609	-0.2107	-0.0171	-0.052	0.6795	0.0925	0.1608	0.5117	-0.153	0.724	-31.3662	88.8264	94.3989
10	0.5035	0.0485	-0.0214	0.5102	0.0867	0.4063	0.035	0.1177	-0.0586	-0.1401	0.0528	0.3691	-0.1309	-0.1295	-0.0746	0.495	0.1709	-0.1813	1.1735	-0.1308	1.1653	-96.321	41.5647	48.1235
11	0.1378	0.0632	-0.0929	0.9571	-0.1599	1.2287	0.0549	0.2578	0.0272	-0.2309	0.0227	0.0448	-0.1371	-0.1904	-0.0825	0.6371	-0.2959	-0.1017	1.2534	-0.1415	0.7705	-86.3732	-32.8087	13.7698
12	0.9578	0.6153	0.1402	1.2217	0.2739	0.3385	0.1293	-0.2697	-0.0129	0.2518	-0.2636	0.0437	-0.0657	-0.0382	0.0763	0.5853	0.1124	0.1471	0.6439	-0.1293	0.6153	-52.1322	66.955	104.4985
13	1.2291	-0.757	-0.1766	0.886	-0.3978	0.644	0.0928	0.0201	0.1475	-0.0411	0.0863	0.0207	-0.0757	-0.0637	-0.1006	1.4716	-0.1915	0.0058	1.6497	0.0347	1.1712	-79.2875	-25.6815	-18.2949
14	0.418	-0.1791	-0.3609	0.3895	0.1928	0.5376	-0.0472	-0.1191	0.081	0.3164	0.0029	0.1368	-0.1197	-0.0896	-0.0118	0.6912	-0.1652	0.2165	0.7895	-0.189	0.495	-60.3886	30.0901	131.4022
15	0.094	-0.0965	0.0734	0.3774	-0.0453	0.0599	0.0537	-0.1351	-0.1552	0.3627	-0.0952	-0.0245	0.172	-0.0413	-0.0144	1.0251	-0.2125	0.0596	0.4264	0.1234	1.0453	-44.7469	-39.3581	115.6191
16	0.4922	0.2272	-0.3031	0.9802	-0.0953	0.9155	-0.088	0.0083	-0.1259	-0.24	-0.0598	-0.091	0.1455	-0.0124	0.0591	0.5537	-0.2149	0.1434	0.916	-0.53	1.0433	-46.7734	-69.7367	21.6352
17	0.4078	0.432	-0.1548	0.7678	-0.1963	0.1586	-0.0936	0.0186	0.0097	0.1492	0.0295	-0.0867	0.1424	-0.0641	0.0371	1.0208	-0.5163	0.2095	0.8692	-0.4384	0.933	-97.7874	-76.9016	73.1083
18	0.0661	-0.0288	0.0495	0.4809	0.6956	1.1479	0.0863	0.1484	-0.3243	0.007	0.0158	0.099	0.0329	0.0692	0.0506	0.6294	-0.3807	0.2706	0.8859	-0.3428	0.8967	-111.8393	-30.0788	97.989
19	0.3233	0.1084	-0.1164	0.4519	0.0124	0.106	-0.0191	-0.087	-0.1819	0.1767	0.1404	-0.1266	0.3446	0.0527	-0.0247	0.7428	-0.1058	0.0398	0.8386	-0.3961	1.1988	-49.1391	-89.8174	49.0354
20	0.4505	0.0624	0.2097	0.6679	0.1707	0.5478	-0.2095	0.1313	-0.1242	0.027	-0.008	-0.2257	0.1863	0.0038	-0.0297	0.957	-0.4185	0.2497	0.781	-0.4635	1.183	-82.5214	-94.7789	51.6417
21	2.0591	0.8838	0.7181	0.7969	0.4393	0.5923	0.0275	0.161	0.1632	-0.1981	0.0032	0.3914	0.0069	-0.1403	-0.023	0.5866	-0.3377	-0.0418	1.1709	-0.4403	1.1574	-107.2025	-55.5528	42.9266
22	0.5399	-0.2177	0.1816	0.3641	-0.055	0.8634	-0.0187	0.1479	0.049	0.1242	0.0915	0.2029	0.0124	-0.241	-0.0913	0.5505	-0.1019	0.4126	1.1236	-0.3265	1.1046	-110.6749	12.0991	101.1151
23	0.521	0.0359	0.1142	0.2043	0.0707	0.3365	0.0239	0.1146	0.2106	0.1399	-0.1042	0.1811	-0.0157	-0.2077	-0.0646	0.4325	0.0123	0.326	0.9042	-0.2405	0.7831	-89.7666	33.1883	101.4289
24	0.2121	0.0058	-0.018	0.4325	0.2462	0.1746	-0.0607	0.126	0.0434	-0.0212	0.0287	0.0825	0.1198	0.0368	0.005	0.3847	-0.0175	0.0818	0.6449	-0.0924	0.4592	-54.3305	21.4507	56.0588
25	0.563	-0.1393	0.3441	0.564	0.0289	0.5173	-0.0774	0.1946	0.054	-0.3324	0.1423	0.2879	-0.113	-0.3157	-0.0796	0.8194	0.3158	-0.1836	1.0561	0.0942	0.8838	-73.8956	76.796	33.3585
26	0.2315	-0.2511	-0.0497	0.2688	0.0531	0.0094	-0.0887	-0.2531	-0.0261	0.127	-0.1235	-0.1028	0.0629	0.1109	0.1068	1.6282	-0.2174	0.0511	1.0131	-0.1542	1.364	-63.6378	-101.7408	81.1498
27	0.4725	-0.0327	0.0288	0.1376	0.1716	0.2287	-0.1082	-0.1903	-0.3157	0.1414	0.0074	0.2431	0.3181	-0.1548	0.0531	0.7932	-0.335	0.2081	0.6718	-0.0576	0.9946	-61.0964	-22.7729	109.171
28	1.049	-0.0521	0.18	0.8764	0.0014	0.1933	0.0731	-0.342	0.071	0.3714	-0.0274	-0.1012	-0.1385	-0.0263	-0.0692	0.813	-0.2356	0.429	1.0037	-0.0774	0.7543	-80.5266	17.3877	140.8202
29	0.9252	-0.2942	0.1543	1.197	-0.0451	1.7985	0.0532	-0.2651	-0.0368	0.3308	0.0137	-0.1552	-0.1114	0.1972	-0.0151	1.3594	-0.3638	0.067	1.1509	-0.2277	0.8205	-76.0603	-56.6698	106.9058
30	0.8895	0.2159	-0.0031	0.4893	0.0981	0.1479	0.0451	0.1269	0.0994	0.0424	0.0173	-0.0549	0.0201	-0.038	-0.0277	0.4492	-0.3285	0.0368	0.9972	-0.3423	0.9177	-79.5771	-47.3697	36.5232
31	0.6167	-0.6337	0.0547	0.6726	-0.0086	0.0652	-0.1385	-0.0509	-0.2733	-0.0688	0.0919	0.3433	0.0343	-0.2643	0.0252	0.6063	0.0073	0.0166	1.073	-0.2592	0.7894	-80.3374	12.8157	37.3531
32	0.217	0.0329	-0.3029	0.4336	0.2386	0.5999	0.1103	0.0902	-0.0132	-0.1814	-0.037	-0.0164	0.1017	-0.1064	-0.0069	1.1498	0.0614	0.124	1.6106	-0.1717	0.9405	-60.4037	-42.6508	-7.2484
33	0.6156	-0.1156	-0.0954	0.6803	0.1437	0.2712	-0.0614	-0.1539	0.1156	0.1761	0.0704	0.2187	0.1253	-0.1212	0.0197	0.9065	-0.6223	0.387	1.2166	-0.4258	1.1388	-132.2246	-57.4563	86.4823
34	0.1041	-0.1072	-0.0211	0.0455	-0.0015	-0.0385	0.1012	0.0211	0.1484	0.0232	-0.0856	-0.1223	-0.0383	0.0206	-0.0402	0.4538	-0.1255	-0.0413	0.7848	-0.1557	0.885	-54.6369	-40.007	40.7297
35	0.1965	-0.1301	-0.2429	0.3042	-0.0007	0.5501	0.0356	-0.0805	-0.0667	0.1578	-0.0524	0.0759	0.022	-0.046	-0.0072	0.3965	-0.1306	0.098	0.5008	-0.046	0.3088	-3.0089	-3.6285	124.0402
36	0.2464	0.0421	-0.0276	0.2662	-0.0226	0.326	0.0642	0.092	0.2047	0.0398	-0.0313	0.0581	-0.2408	-0.0362	-0.0325	0.3994	0.0641	0.09	0.2922	0.1378	0.4918	31.9746	61.0639	38.5464
37	0.1524	0.0478	-0.0343	0.225	-0.0053	0.2626	0.0003	-0.0321	-0.0681	0.0806	-0.0727	-0.1868	0.0033	0.1723	0.074	0.2043	-0.0123	-0.0198	0.4415	0.0999	0.4043	92.158	-24.5023	73.3351
38	0.2952	0.081	-0.0789	0.6348	-0.0566	0.1149	0.1113	0.1698	-0.238	-0.1535	0.0449	-0.0722	0.4412	-0.1348	0.0054	0.8159	-0.1259	-0.1367	0.3451	-0.2642	0.7894	24.1937	-92.8522	30.2855
39	0.1687	0.1059	-0.1662	0.4611	-0.2	0.7159	0.0564	-0.012	-0.1613	-0.0929	-0.0569	-0.2154	-0.1231	0.0729	0.0209	0.2775	-0.0119	0.0884	0.4842	0.1054	0.434	105.5004	12.0823	12.5034
40	0.4347	-0.0268	-0.2677	0.6305	0.2637	0.8171	-0.0319	0.0405	-0.003	-0.0102	-0.0052	-0.1795	0.1758	0.0267	0.0522	0.2828	0.029	0.0526	0.2533	-0.0483	0.2407	75.4493	-31.189	16.9088
41	0.276	-0.3599	-0.1126	0.9063	0.2528	0.2455	-0.0903	-0.1928	-0.1288	0.412	0.007	0.1856	-0.0257	0.0581	0.0625	0.7027	-0.1436	0.1059	0.7792	0.168	0.3668	28.3205	-39.3705	160.8379
42	0.995	-0.2139	-0.2872	0.4787	0.1923	0.2902	-0.0052	0.2508	0.3173	-0.2223	0.0874	0.0984	-0.1104	-0.0993	-0.0654	0.4173	0.084	-0.0013	0.7891	0.2258	0.3933	20.4169	33.0085	-8.8756
43	0.6528	-0.0335	0.0753	0.5754	-0.1786	0.4043	-0.0405	0.1313	0.0021	-0.1648	-0.0946	0.1865	0.0615	-0.1267	0.0964	0.3483	-0.0798	-0.0862	0.646	-0.0357	0.343	11.3272	-26.9626	12.3234
44	0.7282	-0.0521	-0.0128	0.4426	0.0601	0.4081	0.0536	0.0697	-0.1528	-0.1316	0.0904	0.37	0.2772	-0.2717	-0.0864	0.6114	-0.2795	-0.1116	0.8212	-0.1437	0.8884	-12.5914	-78.4548	29.7723
45	0.1405	0.0021	0.093	0.3974	-0.0209	0.5794	-0.0165	-0.1225	-0.1176	0.1372	-0.0929	-0.1202	0.1611	0.1707	0.0806	0.435	-0.018	-0.0548	0.5855	0.2332	0.4092	70.8488	-54.6738	111.439
46	0.4945	0.286	0.158	0.2648	0.1421	0.3013	0.0941	0.1997	0.1762	-0.0816	-0.1408	-0.1524	0.0221	-0.0576	0.0216	0.347	-0.0634	0.086	0.5796	0.0857	0.362	68.2495	14.2225	-15.6915
47	0.138	-0.0099	-0.0036	-0.0056	-0.023	0.2266	0.0333	-0.1984	-0.1758	0.1164	-0.0616	-0.072	0.1662	0.0659	0.0395	0.457	-0.178	-0.0087	0.5587	0.1607	0.2634	41.9802	-31.8051	127.3686
48	0.1119	-0.0111	-0.0968	0.1541	0.169	0.2446	0.0165	0.2414	0.1796	-0.028	-0.0325	0.0097	-0.0459	-0.0904	0.0717	0.2811	0.0728	0.011	0.4271	0.161	0.3132	55.7335	30.0327	12.2229
49	0.2131	0.0119	0.3019	0.6239	0.2025	0.483	0.0776	0.128	0.2137	-0.0343	-0.0005	-0.0575	-0.0245	0.1048	-0.0902	0.3566	-0.0887	0.0028	0.2734	-0.0037	0.3459	72.8914	40.4576	67.6217
50	0.4201	0.0187	-0.0249	0.289	0.0174	0.2226	0.0053	-0.0753	-0.1851	0.0388	-0.0535	-0.0818	0.1068	0.0591	0.081	0.2802	0.0309	0.0434	0.2831	0.1199	0.4395	80.4443	-49.5761	65.4872
51	1.13	-0.1951	0.1559	0.3985	-0.0621	0.4281	0.0564	0.0056	0.194	0.047	-0.0211	-0.0802	-0.1626	0.001	-0.0142	0.6118	-0.0743	0.0388	0.4061	-0.1784	0.5372	36.6942	61.878	111.4702
52	0.9445	0.2413	-0.7185	0.218	-0.3164	0.8454	0.0618	-0.0534	0.0594	0.0223	-0.0268	0.1701	-0.2118	-0.0006	-0.0543	0.5812	0.1084	0.1034	0.5657	-0.2313	0.609	-15.2137	52.1399	118.2482
53	0.4902	-0.3432	-0.0557	0.4419	0.1506	0.3477	-0.1052	0.0204	-0.0689	0.1325	-0.1089	0.1241	0.018	-0.3873	0.1568	0.7569	0.0714	0.1426	0.8212	-0.2227	0.6742	-48.1732	58.4461	133.0509
54	0.3053	0.1338	-0.1829	0.3651	-0.0329	0.2875	-0.0538	0.2398	0.0018	-0.0781	0.1133	0.1827	0.1383	-0.1285	-0.0381	0.3679	0.0038	0.0086	0.5722	-0.0301	0.2632	48.6002	-14.1385	-4.7714
55	0.0307	0.0715	-0.1547	0.1553	-0.2554	0.5948	-0.0382	0.0593	0.0264	-0.164	-0.0046	-0.0124	0.1787	-0.0531	0.0456	0.4098	-0.0283	-0.0389	0.3178	-0.1254	0.4122	45.9201	-54.7019	29.4616
56	0.5799	0.0222	0.5066	1.532	0.1571	1.4639	-0.0291	-0.0571	0.2104	-0.0789	-0.0371	-0.1236	-0.4366	-0.0228	-0.0086	1.2169	-0.0005	-0.0029	0.6216	-0.4825	0.8288	23.8584	89.7087	118.3342
57	0.5422	0.0804	0.0706	0.7562	-0.0632	0.1369	0.0697	0.1807	0.2044	-0.1491	-0.1252	0.0657	0.0046	-0.0225	0.0827	0.3236	0.1405	0.0438	0.4611	0.0057	0.4316	-7.8102	45.4177	48.1021
58	0.6042	-0.3347	0.2894	0.2015	-0.1414	0.1647	-0.0618	0.2389	0.4528	-0.0299	0.0438	0.0281	-0.394	-0.2143	0.0304	0.6447	0.143	0.1358	0.4814	0.0811	0.9245	-5.1407	81.1934	56.8166
59	0.3794	-0.1128	0.1372	0.0992	0.0893	0.2979	0.0068	-0.1515	-0.0308	0.2253	-0.0296	-0.072	0.0219	0.02	0.0577	0.6107	-0.1551	-0.0077	0.5795	-0.1743	0.3412	52.1367	25.0692	143.0233
60	0.4689	0.0663	0.0445	0.4983	0.0093	0.436	0.0537	-0.1119	-0.022	0.0894	0.0658	-0.2275	-0.1154	0.2338	-0.0961	0.3856	-0.2085	-0.143	0.6943	0.0111	0.3956	100.4389	11.7821	113.9039
61	0.3164	-0.1532	-0.0216	0.3195	-0.125	0.647	-0.1125	-0.2316	-0.0319	0.162	-0.0355	0.0817	-0.0041	0.017	0.0225	0.9137	-0.0579	0.3163	0.9837	-0.21	0.3267	-7.8802	27.6923	173.371
62	0.0465	0.1167	-0.0773	0.5048	-0.199	0.234	0.0035	-0.0119	-0.1176	-0.0081	0.0073	0.0492	0.1247	0.0584	-0.0125	0.2323	-0.0418	-0.0137	0.3243	0.0894	0.3274	66.1021	-53.8055	83.7837
63	0.0123	0.0697	0.0555	1.3305	-0.1691	0.3378	0.0144	0.0424	-0.1845	-0.1277	-0.0113	-0.2669	0.1357	-0.025	0.0061	0.3668	-0.0238	-0.0219	0.421	-0.0984	0.526	55.7617	-55.9725	51.2226
64	0.5191	-0.3605	0.2295	0.5807	-0.0768	1.2037	0.0179	-0.0886	-0.0136	0.0771	-0.0318	0.2177	-0.0277	-0.3009	0.0173	0.601	-0.0478	0.3546	1.081	-0.194	0.5653	-32.5604	23.632	152.2644
65	1.1496	0.4637	0.013	1.952	0.0434	1.3135	0.0181	-0.0143	0.1922	0.0937	-0.075	-0.2001	-0.2625	0.2116	-0.0227	0.4278	-0.0327	0.0939	0.2417	-0.0435	0.5195	43.8002	71.9465	80.7804
66	1.2193	0.0103	0.2919	0.1044	-0.0543	0.4203	0.0442	0.0921	-0.0296	-0.0601	-0.0282	-0.1228	-0.1161	0.1853	-0.0331	0.2634	-0.0411	0.0121	0.341	0.0716	0.352	89.3214	-0.0583	57.6753
67	0.6111	-0.0802	-0.2276	0.8891	0.0923	1.0017	-0.0319	0.0148	0.0035	0.1022	-0.0193	-0.22	-0.0293	0.0695	0.0248	0.2656	-0.0424	0.0623	0.4368	0.1093	0.2702	81.1903	14.3396	22.1692
68	0.6025	-0.0249	-0.4048	0.0657	-0.1437	0.5914	-0.122	-0.2016	-0.0644	0.0981	-0.0125	-0.1305	0.0424	-0.0291	0.0412	0.6242	-0.1095	0.164	0.6507	-0.1866	0.3694	5.925	27.6881	144.0353
69	0.2156	-0.0716	-0.027	0.7614	0.1146	0.1818	0.0099	-0.3851	0.008	0.1854	0.0351	-0.1506	0.0329	0.0084	-0.0447	0.4721	-0.1053	-0.1022	0.8193	-0.0287	0.2732	72.9454	-0.5046	141.5295
70	0.6221	-0.4163	-0.2588	0.36	0.3276	0.5987	-0.073	-0.0158	-0.2955	0.104	-0.0133	0.084	0.2413	-0.198	0.1062	0.6431	-0.2829	-0.0261	0.5102	0.2189	0.4785	36.2031	-63.2434	127.2705
71	0.3793	-0.3746	0.1235	0.8032	-0.2439	0.7511	-0.1071	-0.0377	0.1721	0.17	-0.0021	-0.036	0.0668	0.0735	0.0797	0.3786	-0.1075	-0.0155	0.4239	-0.0016	0.2634	53.0035	2.8994	117.6186
72	0.591	-0.0572	-0.0406	1.2022	0.2422	1.4305	-0.0029	-0.0321	0.0911	0.1331	0.0017	0.0486	-0.1505	-0.1391	0.0805	0.8466	-0.0656	-0.001	0.7037	-0.3872	0.3266	28.6306	61.8247	154.917
73	1.2854	0.0049	0.0911	0.2789	-0.0355	0.1128	0.0079	0.1847	0.0774	0.0845	-0.0548	-0.0644	-0.1527	-0.041	0.0131	0.5555	-0.1044	-0.0259	0.5113	-0.0762	0.2681	58.8139	24.0312	111.903
74	0.447	0.2162	0.3791	0.8	-0.3376	1.2561	0.0057	0.0613	-0.0253	-0.0993	0.0626	0.1708	0.0312	-0.1873	-0.0811	0.2397	0.0747	-0.0519	0.6844	0.1509	0.3886	7.5672	17.286	2.8294
75	0.2855	0.3391	-0.4822	0.4087	-0.5827	0.8325	0.0192	-0.0033	0.0104	0.0917	-0.0937	0.1539	-0.071	0.0715	0.0038	0.5233	-0.0921	0.086	0.5872	-0.0052	0.5027	-35.3455	5.5754	82.0492
76	0.3376	0.4283	0.1991	1.4723	0.6115	1.0689	0.0249	0.0135	-0.0996	0.0579	-0.0605	0.1239	0.3016	-0.2447	-0.0075	0.4918	-0.1897	0.0639	0.3666	0.0619	0.5005	20.03	-60.6291	77.079
77	0.4234	-0.0306	-0.0201	0.3291	0.0659	0.5408	0.0606	-0.2269	0.0809	0.2733	-0.0475	0.1231	-0.0866	-0.1801	-0.0613	0.4832	-0.0442	0.2189	0.6149	-0.1266	0.3719	-17.8174	14.1587	123.2363
78	0.6036	0.0182	-0.3018	-0.0067	-0.0149	0.505	-0.0253	-0.0481	-0.0941	-0.1981	-0.1323	-0.2358	0.188	0.0549	0.069	0.4893	0.2587	0.5066	0.7522	0.4011	1.3844	293.5158	-1.515	217.1276
79	0.4931	0.1871	0.1534	0.7338	-0.0465	0.3359	-0.0359	0.3426	-0.1441	-0.3406	-0.1112	-0.0959	0.2092	-0.0201	0.1396	0.6223	0.2081	0.2454	0.7386	-0.1676	0.6529	237.6555	-25.1252	176.5216
80	0.7817	-0.0149	-0.1558	0.5662	-0.1409	0.7875	-0.0311	-0.0603	0.1447	0.1014	-0.1005	-0.3698	0.0299	0.3461	0.1087	0.4094	-0.0597	-0.1259	0.5177	0.2264	1.077	276.3604	17.019	246.6062
81	0.1246	0.0209	-0.0881	0.386	0.018	0.3969	0.4515	-0.3689	0.4298	0.5365	-0.1296	-0.183	-0.3523	0.287	-0.2246	1.3588	-0.3149	0.2899	0.6552	-0.0445	0.8268	272.541	-22.8148	277.9195
82	0.1718	0.1483	-0.2387	0.4264	-0.0628	0.3751	0.0462	0.0552	0.1613	0.0414	-0.0164	-0.4022	-0.1142	0.2623	-0.0241	0.6447	-0.234	-0.2031	0.338	0.1524	1.2594	251.8785	87.5138	243.6302
83	0.6343	0.3455	0.0841	0.2997	-0.0314	1.2599	-0.0721	0.3116	-0.0952	-0.2699	0.0909	-0.1176	0.4437	-0.2142	-0.0332	1.0364	-0.1365	0.1479	0.5888	0.0431	0.5744	254.2532	-69.8505	230.5562
84	0.6569	0.079	-0.1352	0.5261	-0.0983	0.4712	-0.0705	0.0003	0.235	0.3755	-0.0571	-0.2169	-0.2126	-0.0705	0.113	0.8823	0.0275	-0.0884	0.2768	-0.015	0.833	196.5907	103.0458	255.2045
85	0.6898	0.1108	-0.0236	0.5481	-0.1019	1.0811	-0.0815	0.1992	0.1763	-0.1898	-0.057	-0.0799	-0.2771	0.0791	-0.106	0.5773	-0.1673	0.2561	0.9802	0.4589	1.1537	284.5677	52.7653	186.1061
86	0.2737	0.0276	0.0138	0.5253	-0.1461	0.3467	0.0702	0.1739	0.1735	-0.1732	-0.1497	0.0748	-0.246	-0.0552	0.0285	0.7508	0.0397	-0.0261	0.4173	0.2141	0.7226	209.4526	91.9504	210.224
87	0.524	0.0992	0.095	0.6961	0.0144	0.6519	0.0242	-0.0298	0.1331	0.2678	-0.0384	-0.3748	-0.0625	0.2074	-0.0503	0.5739	-0.1468	-0.4397	0.6067	0.0633	1.1647	264.7534	49.9434	271.6348
88	0.077	0.0701	0.1568	0.1584	0.0166	0.445	-0.004	-0.2176	0.0311	0.1746	-0.0864	-0.2549	0.0841	0.2017	0.0386	1.618	-0.2988	0.4159	1.0703	-0.4351	1.3631	255.9285	-27.1345	307.75
89	0.6627	-0.6399	0.4011	1.2924	-0.3131	0.3696	-0.024	0.0928	0.1073	-0.3218	-0.0839	-0.1612	-0.1947	0.0556	0.0196	0.5935	-0.0533	0.1119	0.44	0.221	0.7026	232.4041	71.279	206.7994
90	0.2997	-0.0899	-0.0779	0.0245	0.0245	0.0203	0.0291	-0.0432	-0.0242	0.0651	-0.0363	-0.2343	-0.0038	0.0317	-0.0251	2.508	-0.1745	0.5115	2.0721	-0.3536	1.9272	245.0869	-19.7343	339.3102
91	0.2003	-0.0662	-0.1351	0.4661	-0.048	0.3966	-0.0083	0.033	0.1237	-0.2165	-0.1003	-0.1542	-0.0723	0.3103	0.0084	0.5785	0.0195	0.201	0.813	0.1999	0.5922	247.762	33.3377	183.5286
92	0.2913	-0.0021	0.0927	0.9577	0.3337	0.4061	0.0643	0.1502	-0.1865	0.0872	-0.0747	0.1409	0.3208	0.2072	-0.0269	0.6581	0.1729	0.0918	0.5415	-0.1463	0.8007	231.187	-36.8082	198.7725
93	0.6524	0.032	-0.103	0.6282	0.0642	0.7725	0.2415	0.0268	0.2684	0.2639	-0.0739	0.2487	0.0082	-0.3743	-0.1086	0.973	0.1983	0.5883	0.8125	0.4899	1.1808	214.173	-59.6866	293.9444
94	0.7099	0.0327	-0.4608	0.8987	0.3016	0.7944	-0.0986	0.0458	-0.0239	-0.0827	-0.0122	-0.2583	0.3744	0.2993	0.1012	0.8312	0.2112	0.2223	0.5325	0.1668	0.912	272.6732	-70.6105	251.0157
95	0.0482	0.1448	-0.1673	0.6406	-0.6524	0.6524	0.1875	0.0666	-0.0093	-0.24	-0.2175	-0.3155	-0.0075	0.0155	0.0684	0.6652	0.1735	0.1634	0.7986	0.2063	1.1109	292.7088	-25.2474	229.5222
96	0.6446	-0.0402	0.0614	0.8695	-0.2617	0.2419	0.14	0.2982	0.1329	-0.1547	0.1556	0.2804	0.258	-0.5017	-0.0664	0.8941	-0.2291	0.1089	0.9225	0.5176	0.8502	220.3238	-80.9189	267.3985
97	0.8209	0.0207	0.1552	0.7867	-0.1925	0.508	-0.12	-0.0328	-0.1668	-0.0386	0.0613	-0.1495	0.3283	0.0868	0.0319	1.0712	0.1183	0.1141	0.4273	0.2202	0.7878	253.5349	-87.3416	269.9959
98	0.3363	0.2761	0.0823	0.4287	0.0536	0.8297	0.216	-0.3994	0.217	0.545	-0.0328	-0.2014	-0.3348	0.2723	-0.1617	0.9207	-0.1691	-0.2195	0.7322	0.1765	0.9083	279.1702	-49.9493	282.7055
99	0.5442	0.1473	0.0781	0.2162	0.2162	1.3484	-0.1606	0.0114	0.0605	-0.0419	-0.143	-0.2329	0.1025	0.2674	0.1141	0.351	0.0155	0.1178	0.8197	0.3383	1.1752	291.0538	18.8774	224.4367
100	0.5252	-0.0251	0.133	0.4316	-0.0867	0.4247	0.0066	-0.0173	0.2352	-0.0424	-0.153	-0.3392	-0.0753	0.1794	0.1074	0.3383	-0.0768	0.1153	0.5906	0.1789	0.8957	269.9615	38.8052	218.8151
101	0.3097	0.1055	0.0146	0.5209	-0.1899	0.1759	-0.0232	0.021	0.0494	0.2497	-0.0574	-0.1896	-0.1233	-0.0087	0.0966	0.4341	-0.0388	-0.0592	0.2981	0.0722	0.5312	226.2488	27.4657	256.3579
102	0.8581	0.1023	0.4455	0.3267	0.0065	0.4347	0.0449	-0.2999	0.075	0.3205	-0.1115	-0.3431	-0.2069	0.001	0.0435	1.0584	-0.148	-0.4341	0.4191	-0.1307	0.9339	238.542	84.8909	279.2781
103	2.0237	1.0387	0.2371	1.1024	0.0315	1.5827	0.0578	0.1615	-0.2209	-0.1404	0.0095	0.0664	0.1121	-0.1437	-0.0128	1.6524	-0.352	0.1774	0.666	0.0974	0.8344	239.0946	-94.0173	238.2182
104	0.2984	0.2391	0.2142	0.2218	0.2292	0.6111	0.0151	0.1884	-0.2154	-0.0518	0.0951	-0.1682	0.1523	0.2822	-0.0433	0.3924	0.1345	0.1052	0.5144	0.0225	0.839	245.4341	-18.4902	208.0962
105	1.0307	0.055	-0.1049	0.8725	0.029	0.1747	0.0692	0.334	0.0771	-0.3672	0.0051	-0.1072	-0.1233	0.1321	0.0389	0.5043	-0.0574	0.4041	0.832	0.137	0.8148	269.62	21.1227	179.0569
106	1.4936	-0.0311	0.0509	2.0374	0.1894	2.0765	0.0599	0.428	-0.0916	-0.3898	-0.0296	0.0981	-0.0622	-0.0672	-0.0038	1.2531	-0.1353	0.354	0.8943	0.2636	0.764	257.3168	-50.0718	214.0357
107	0.5136	-0.2884	0.1693	0.9282	0.2922	0.2493	0.0563	-0.3272	0.0378	0.3868	-0.1029	0.2627	-0.03	0.0037	0.0278	1.3126	0.119	0.3698	0.6147	0.0083	0.8206	250.4371	-40.0187	284.1052
108	1.4261	1.1925	0.3279	1.0817	0.4347	0.4575	-0.131	-0.0546	-0.25	0.2786	0.0466	-0.3919	0.0656	0.2482	0.0632	0.7476	-0.0252	-0.1874	0.5606	0.1927	0.7084	248.2598	20.6429	280.6274
109	0.1851	-0.0742	0.2213	0.3059	-0.3886	1.4535	0.0132	-0.0483	0.0192	0.039	-0.0381	-0.1232	0.087	0.1976	0.0437	1.8364	-0.0869	0.2753	1.7256	-0.45	1.5368	226.5859	-34.5396	322.1661
110	0.7347	0.0531	-0.2181	0.4754	-0.0241	0.4692	0.0137	-0.1559	-0.0746	-0.0801	-0.0522	-0.432	0.2603	0.5523	-0.0569	0.641	0.4093	0.1971	1.3167	0.2739	1.5965	309.128	-53.0413	242.1147
111	0.1879	0.0935	0.0012	0.0204	0.0464	-0.0409	0.1398	-0.1793	-0.0459	-0.1022	-0.0065	-0.0605	-0.1484	-0.0118	-0.1496	0.7145	-0.1757	0.1066	0.7031	0.0931	0.947	216.5809	-39.3952	280.6099
112	0.4371	0.0304	-0.4299	0.3006	0.1561	0.5318	0.0269	0.3166	0.0152	-0.0573	0.0515	-0.1377	0.1696	-0.0274	-0.0901	0.4149	0.0532	0.0476	0.5385	-0.1202	0.3487	191.7256	-6.6173	183.5544
113	0.1696	-0.0627	0.0839	0.4458	0.0076	0.3332	0.0226	-0.0047	0.1668	0.0827	0.0286	0.0272	-0.1883	-0.0162	-0.0207	0.348	0.0341	0.0383	0.0262	0.1062	0.517	136.6246	66.1448	249.8165
114	0.181	-0.0618	0.1229	0.1457	-0.0263	0.2588	0.0853	0.1027	-0.0941	-0.0981	0.0455	0.132	0.1189	-0.1556	-0.0474	0.4219	-0.1409	-0.16	0.4041	0.0133	0.3665	87.8703	-25.9323	213.8139
115	0.3825	-0.0822	0.037	0.8092	-0.3357	0.1278	0.0452	-0.1138	-0.2223	0.1324	0.1512	0.2395	0.1668	-0.1332	-0.0512	0.6638	-0.0201	-0.2212	0.148	0.1542	0.6181	144.4071	-84.8247	280.3855
116	0.3598	-0.1885	-0.135	0.6019	0.2964	0.5178	0.1556	-0.0181	-0.0817	0.0498	-0.0971	0.1338	0.0322	-0.2828	-0.0387	0.3005	0.0398	0.0472	0.4732	0.1522	0.3883	60.1725	16.9699	264.8951
117	0.5789	0.0005	-0.1928	0.6077	-0.1004	0.5548	-0.0315	0.0214	-0.1591	0.1078	0.1038	0.213	0.1306	-0.1389	-0.0165	0.3685	-0.104	-0.0047	0.1822	0.1501	0.3416	91.293	-24.9691	272.9643
118	0.1552	0.0534	0.0053	0.5898	-0.061	0.3785	-0.0274	0.2687	-0.167	-0.1446	-0.0223	-0.1309	0.241	0.173	0.0162	0.926	0.1384	0.0684	0.935	-0.4178	0.4442	170.0915	-48.1702	145.7377
119	1.4088	0.3374	-0.362	0.4358	0.0246	0.2512	-0.0307	-0.2041	0.0977	0.1074	0.0362	-0.1133	-0.0443	-0.055	-0.0356	0.4623	0.0263	0.0004	0.2386	-0.0606	0.2419	137.892	44.3121	302.0075
120	0.3376	-0.0969	-0.1036	0.5423	0.2014	0.1492	-0.1734	-0.1992	0.0347	0.4994	-0.0598	-0.2588	-0.1992	0.0262	-0.3852	1.0213	0.2227	-0.5234	0.2239	0.037	0.4606	153.4799	-16.4594	290.459
121	1.0229	0.0624	-0.0599	0.3796	-0.0509	0.4977	-0.0923	0.0807	-0.0785	0.0704	0.0377	-0.2516	0.0349	0.1468	0.084	0.5642	0.0643	-0.1415	0.2735	0.0059	0.5984	180.3866	-69.3067	286.9038
122	1.0142	0.619	0.1304	2.4947	-0.2053	0.56	-0.0018	-0.0981	-0.2429	0.1096	-0.1224	-0.087	0.1317	0.1508	0.0466	1.0049	-0.2231	-0.2321	0.4467	0.175	1.0485	172.7612	21.6509	346.1933
123	0.1491	0.0723	-0.0401	0.4407	0.0645	0.5148	0.0458	0.1736	-0.1422	-0.1963	0.0629	-0.0448	0.2728	-0.0155	-0.0433	0.6705	-0.0569	-0.2205	0.5382	-0.2374	0.4511	117.9902	-59.5219	185.7694
124	0.5868	-0.3349	0.2683	0.3048	-0.2335	0.6381	0.022	-0.0861	0.1299	0.0176	0.1429	0.1139	0.0047	-0.0835	-0.1117	0.3649	0.0559	0.1187	0.3033	0.0662	0.3482	90.1258	24.5854	300.3385
125	0.0321	-0.0348	0.0329	0.0169	-0.0487	0.0756	0.0185	0.1787	-0.2501	-0.188	0.0402	-0.0886	0.1373	0.0138	-0.0556	0.6936	0.0252	0.0016	0.6004	-0.2832	0.3839	149.2895	-37.2953	173.9758
126	0.3326	0.049	0.0379	0.1139	-0.0687	0.2048	-0.0203	-0.0918	0.0999	0.0945	0.0526	-0.0263	-0.0267	0.0424	-0.0462	0.2847	0.0218	0.0405	0.1216	0.0039	0.2631	108.2925	37.4463	273.9752
127	0.7338	0.1033	0.4176	0.3741	-0.1196	0.5424	0.0874	0.117	0.1328	-0.0677	-0.0281	0.0626	0.0877	-0.2114	-0.1096	0.3487	0.0511	-0.0231	0.3238	0.1505	0.3537	109.7102	41.111	210.7698
128	0.2368	0.0013	-0.0507	0.192	-0.0302	0.1846	0.0616	0.0374	-0.054	-0.0923	0.0091	-0.0122	0.0479	-0.0737	-0.066	0.469	-0.1332	-0.1293	0.3151	-0.0576	0.479	97.8388	-49.2731	227.2693
129	0.4447	0.1606	0.1488	0.4844	0.1076	0.4929	-0.0017	0.1439	0.1161	-0.109	-0.0074	0.0041	-0.1067	0.1045	0.045	0.6167	-0.0645	-0.0234	0.5808	0.2524	0.3058	148.6856	57.8356	178.2173
130	0.979	-0.1154	-0.4176	0.2569	0.0386	0.58	0.0183	0.1177	0.0625	-0.0395	-0.0398	-0.1409	-0.0374	0.0769	-0.0091	0.4809	-0.1003	0.0767	0.4984	0.188	0.4808	200.696	50.1815	184.5366
131	1.215	0.4794	0.2802	0.1816	0.1081	0.0609	-0.1601	0.2437	0.1375	-0.0829	0.0297	-0.2223	-0.0912	0.2405	0.1227	0.6885	-0.0978	0.1328	1.0179	0.213	0.6116	235.8113	60.507	177.7348
132	0.2759	-0.0465	-0.0592	0.4476	-0.068	0.2947	0.0267	-0.147	-0.0438	0.0764	-0.0204	-0.0908	0.0296	-0.0432	-0.0177	0.4142	-0.0097	-0.0166	0.2759	0.0358	0.2327	112.1437	-4.0165	297.858
133	0.1052	-0.1675	-0.212	0.1905	0.2938	0.3606	0.0339	-0.0317	-0.1236	0.1219	-0.0145	0.1014	0.0782	0.0299	0.0063	0.5353	-0.024	-0.0771	0.2084	0.0816	0.3894	123.3717	-48.0769	270.6881
134	0.3683	-0.4071	0.0103	0.9243	-0.4589	1.5986	-0.0233	0.1114	0.0949	-0.0488	0.0387	0.0594	-0.2248	-0.1381	-0.1528	1.0014	-0.147	-0.0494	0.729	0.4668	0.4934	161.5627	85.3879	171.1181
135	0.5066	-0.0162	0.2309	0.5929	0.0489	0.2018	0.124	-0.2191	0.1976	0.0577	-0.0731	-0.2651	-0.0213	0.0776	-0.0226	0.3777	-0.0485	-0.0166	0.2022	0.073	0.4352	177.7633	51.3735	251.6864
136	0.2731	0.5251	0.2498	0.8666	0.4392	0.1667	-0.1137	0.0268	0.1779	0.1076	0.1206	0.1178	-0.2011	0.0748	0.0189	0.765	-0.0747	-0.0279	0.3599	0.0674	0.7026	190.7939	100.2665	248.1773
137	0.2016	0.055	0.0341	0.0172	-0.0148	0.36	-0.0032	0.2867	-0.0764	-0.2112	-0.0087	0.0253	-0.1219	-0.0425	-0.0499	0.6494	-0.1143	-0.1461	0.8917	0.1953	0.2089	141.6454	16.9402	149.2112
138	0.4565	-0.4932	0.026	0.5544	-0.0801	0.4006	0.1589	0.3472	0.0273	-0.0966	0.0579	0.0891	-0.0824	0.0058	0.085	0.5932	-0.1242	-0.3148	0.7725	0.1405	0.3316	88.5468	4.6082	168.1151
139	0.1566	0.0135	-0.1391	0.2238	0.0645	0.6145	0.0203	0.157	-0.0232	-0.1737	0.0251	-0.0312	-0.0327	-0.0051	-0.0089	0.8189	-0.1224	0.2941	1.4028	0.0219	0.3528	207.2516	18.4632	132.9781
140	0.1805	-0.0895	0.0248	0.3492	-0.0003	0.0629	0.0376	0.0745	-0.0522	-0.0519	0.0494	0.0705	0.1617	-0.0339	-0.0837	0.5364	-0.097	-0.1154	0.3735	-0.1143	0.3985	116.0419	-55.0046	213.4016
141	0.0221	0.1001	-0.0277	2.2423	-0.1415	0.2069	0.0321	0.0347	-0.0962	-0.0709	-0.0002	0.2265	0.1315	-0.0513	0.0008	0.5116	-0.063	-0.1799	0.3311	0.0103	0.4365	118.5335	-52.5492	247.6234
142	0.5164	0.0002	-0.51	0.6549	0.4216	1.262	0.0563	-0.0912	0.001	-0.0313	-0.0093	-0.2092	0.018	0.3188	0.0375	0.4271	-0.0898	0.2798	1.0449	0.0486	0.5006	226.8103	18.5519	159.891
143	1.5066	-0.6888	-0.0611	1.9277	-0.2305	1.3882	-0.0525	0.1691	0.1071	-0.1403	-0.0136	0.2023	-0.06	-0.2236	0.0528	0.444	-0.0409	0.0179	0.3678	0.1892	0.4564	134.4476	71.4268	205.0154
144	0.9956	0.1006	0.5021	0.2075	0.1886	0.6474	0.0744	0.0236	-0.0273	0.031	0.0683	0.2083	-0.1272	-0.2532	-0.1379	0.2751	-0.046	-0.0821	0.3943	0.0743	0.3584	86.5487	0.3365	226.4659
145	0.9951	-0.0883	-0.3823	1.0122	0.0521	1.0871	-0.0212	0.1257	0.125	0.0094	0.0353	0.0341	-0.0762	-0.1848	-0.0421	0.2239	0.0064	0.037	0.219	0.089	0.3576	86.0344	19.4133	260.7736
146	0.3605	0.0849	-0.2077	0.0432	-0.0085	0.1694	-0.2123	0.3287	-0.1258	-0.0957	0.0896	0.0523	0.065	0.183	0.0336	0.5842	-0.0475	0.134	0.9284	0.0497	0.3112	186.9879	21.5156	158.2227
147	0.2784	0.0816	0.0604	0.7219	-0.1579	0.1073	0.0125	0.3765	-0.0224	-0.2917	0.1081	0.025	0.1611	-0.0742	-0.0855	0.6911	-0.0918	-0.1327	0.9114	-0.0265	0.2726	121.9194	-9.5403	149.089
148	0.6355	0.4298	-0.1614	0.3158	-0.1381	0.4085	0.0244	-0.0351	-0.2191	-0.0974	0.0255	-0.1011	0.2546	0.2516	0.012	0.7904	0.1386	-0.0173	0.502	-0.2752	0.533	155.5903	-68.1219	179.4881
149	0.3805	0.436	0.2238	0.8649	0.5319	0.9454	-0.0693	0.28	0.126	-0.1283	-0.0336	0.0095	0.0733	-0.1567	0.1057	0.5413	-0.0374	-0.0189	0.5638	0.0035	0.2355	135.6177	-2.2705	176.2702
150	0.6184	0.1154	-0.3853	1.6813	-0.2739	1.0395	0.0695	-0.0122	0.1297	-0.1844	-0.0833	-0.1499	-0.0695	0.1482	0.0519	0.8924	-0.0722	0.0771	0.9707	0.3774	0.3895	166.3182	52.7984	138.2239
151	0.8345	-0.1701	0.1903	0.4449	-0.0043	0.5419	0.0713	-0.1436	0.1071	-0.0995	0.0869	0.1733	0.0024	0.0452	-0.1067	0.5006	-0.062	-0.0873	0.6456	0.1462	0.3879	128.1352	19.1211	177.7248
152	0.6064	0.1345	0.259	1.3192	0.6969	1.3872	-0.1348	-0.1019	0.0013	0.1544	0.0616	-0.0915	0.0352	0.06	0.1023	0.4056	-0.0297	-0.0927	0.2116	-0.0526	0.3057	153.3357	28.1484	295.3657
153	0.6194	-0.6345	-0.6411	0.6462	0.6543	0.659	-0.0164	0.2265	-0.0075	-0.2097	-0.154	-0.0085	-0.1221	-0.1543	0.0938	0.3179	-0.0994	-0.0052	0.3413	-0.0363	0.4984	213.5559	9.609	228.3839
154	0.2687	-0.3423	-0.02	1.1723	-0.6859	0.8449	-0.0703	0.0941	0.0376	-0.0575	-0.0586	-0.3421	0.2252	0.0251	0.1009	0.6036	0.0824	-0.063	0.2607	-0.1366	0.4581	159.181	-58.8704	231.3778
155	0.4325	-0.1833	-0.3188	0.1551	0.2509	0.7285	0.1125	0.1832	0.1048	-0.1968	0.0348	-0.2285	-0.1284	0.0983	-0.0724	0.3922	-0.0226	0.1289	0.6332	0.0256	0.3653	205.4794	12.0434	185.364
156	1.2125	0.1471	-0.2603	0.6331	-0.2633	0.9036	-0.0498	-0.3027	0.3029	0.2911	-0.0543	0.0366	0.028	-0.0891	0.1168	1.3031	-0.2133	-0.016	0.7286	-0.059	0.6442	133.8221	15.1824	349.1796
157	0.4077	0.0382	0.1566	0.7447	0.0405	0.0614	-0.043	0.0356	0.1488	0.0115	-0.0207	-0.1974	-0.109	0.2244	0.0316	1.8454	-0.1254	0.2602	1.8999	-0.0253	1.7457	116.9954	15.4973	368.3437
158	0.0003	-0.0012	0.0001	0.0035	-0.0011	0.0009	0.0014	0.1098	0.0545	-0.0646	0.0033	0.256	-0.093	-0.2912	-0.0083	2.4874	0.0165	0.1645	2.4202	0.004	2.3352	102.2363	12.7023	377.047
159	0.2155	0.009	-0.0505	0.1261	-0.0246	0.1809	0.0423	-0.0332	0.0275	0.0443	-0.0423	-0.0072	-0.0248	-0.0154	-0.0093	0.248	-0.0607	-0.0059	0.2786	-0.0067	0.2734	39.2145	2.1365	75.6664
160	0.6689	0.1068	-0.2581	0.0133	-0.0381	0.0976	-0.0033	-0.1339	-0.3386	0.1079	0.1798	0.7396	0.2105	-0.6449	-0.0781	0.9025	-0.3859	-0.1062	1.5406	0.0215	1.3776	-17.1254	-48.6465	14.9116
161	0.1486	0.0645	0.0266	0.0253	0.0115	0.0021	-0.1803	0.0197	-0.0922	-0.0456	0.0209	0.8757	0.0997	-0.4809	0.095	1.3519	0.1086	-0.1459	1.8115	-0.0915	1.3877	-2.3595	-0.1363	-24.9655
162	0.3214	-0.3129	-0.4711	0.5905	0.3956	0.7011	-0.1224	-0.7081	0.4569	0.5187	-0.178	-0.1162	-0.5415	-0.0719	0.2511	1.1455	-0.0638	0.013	1.0823	-0.1651	0.7656	28.0635	0.9879	155.7337
163	0.8374	0.4737	-0.5768	0.9648	0.1209	0.7019	0.1808	0.0862	-0.0307	-0.1019	-0.0323	0.0849	0.1754	-0.0117	-0.0968	0.669	-0.0216	0.0854	0.785	-0.2537	0.7058	-29.7111	-15.5918	61.5271
164	0.133	-0.0221	0.359	0.0041	-0.0551	1.0202	-0.0165	-0.1786	-0.6295	-0.041	0.1361	0.6915	0.7833	-0.7078	-0.0852	2.1081	-0.1849	-0.0466	2.1693	-0.2495	2.0157	-21.7405	-27.3709	163.3726
165	1.0624	-0.6746	-0.6932	1.4331	-0.5825	1.5468	0.1149	-0.4202	0.3818	0.4834	0.0546	-0.6662	-0.326	0.4254	-0.0881	1.4188	-0.0658	-0.0021	1.4403	-0.0293	1.0544	11.7862	-2.2325	182.1016
166	0.0002	0.0305	0.0379	0.4782	0.6121	0.7768	-0.0074	-0.5066	0.6008	0.5163	0.2341	-0.0375	-0.5596	-0.0392	-0.1478	1.0612	0.1183	0.1073	0.7945	-0.3325	1.0654	-4.7835	88.8131	100.6392
167	0.2189	0.2131	0.1903	0.6162	0.0083	0.1752	0.0284	0.2205	-0.2061	-0.3593	0.0105	0.0132	0.2251	-0.0142	-0.0284	0.5912	-0.1193	-0.0443	0.5465	-0.2316	0.5415	23.7042	-66.6362	16.8149
168	0.2311	0.0349	-0.0595	0.1967	-0.0857	0.4221	0.0876	-0.2926	0.0684	0.2087	-0.0403	-0.0704	-0.1045	0.1539	-0	0.4744	-0.1396	-0.0529	0.6346	-0.0512	0.311	63.1219	7.8045	126.2371
169	0.2528	0.0379	-0.0535	0.4374	-0.0445	0.2207	0.0142	0.1081	0.1386	-0.1146	-0.0498	0.2343	-0.1737	-0.2557	0.0257	0.5094	0.2132	-0.0002	0.7291	-0.0663	0.6212	-54.2364	63.3283	62.642
170	1.4007	0.9896	-0.9566	3.8112	1.7617	2.6315	-0.1788	0.4129	0.472	-0.5574	-0.0973	0.6	-0.5777	-0.5173	0.172	1.0106	0.3794	-0.2147	1.0876	0.146	0.9573	-49.4023	101.9431	34.3288
171	2.0348	-0.081	0.7197	3.9462	0.5927	0.3516	0.0479	-0.2926	0.1963	0.3174	-0.022	0.2584	-0.2198	-0.2489	0.0066	1.5098	0.3874	-0.0389	1.4765	-0.1785	1.7599	-42.7406	127.7074	104.0743
172	0.7122	0.2247	-0.0964	0.0729	-0.0335	0.0148	0.0465	0.1652	0.5675	0.0059	0.067	0.1127	-0.5566	-0.1708	-0.0486	1.6888	0.0352	0.1926	1.6985	-0.2332	1.8341	-59.3479	113.3894	117.9709
173	0.1426	0.3471	0.0474	0.836	0.1166	0.0195	-0.1514	-0.3595	-0.475	0.3527	-0.1294	0.4717	0.4342	-0.2961	0.1582	2.361	-0.1123	-0.1593	2.3328	-0.1293	2.2081	-112.3806	14.7682	27.4793
174	0.4007	-0.0002	0.0172	0.4101	-0.286	0.1974	0.0371	0.2848	-0.0036	-0.3118	0.0756	0.1512	0.0257	-0.3762	-0.1329	0.7823	0.2375	-0.2049	1.3899	0.0041	0.8678	-83.6549	48.6864	24.5019
175	0.4937	0.0677	-0.0615	0.6413	0.0113	0.3397	0.103	-0.1256	-0.0907	0.3246	-0.1696	0.19	0.0778	-0.2593	0.057	0.4836	-0.1543	0.1501	0.6776	-0.1716	0.5395	-60.5154	10.5082	106.0018
176	0.4705	0.3704	-0.1315	0.6715	0.5167	1.0396	0.081	0.2833	0.2422	-0.2991	0.229	0.436	-0.411	-0.6567	-0.1902	1.2661	0.3313	0.0418	1.7846	-0.4303	1.8718	-109.1105	58.0748	96.5527
177	0.0037	-0.0074	0.0097	0.0096	-0.0161	0.016	-0.1718	-0.0024	-0.0173	-0.1845	-0.0533	0.6168	0.0421	-0.465	0.159	2.145	0.086	0.0978	2.2708	-0.1649	2.0213	-99.9149	79.5013	108.7981
178	0.134	-0.088	-0.323	0.556	-0.2817	1.2324	0.027	0.0188	0.1668	0.1411	0.0459	0.1999	-0.3484	0.1852	-0.0025	0.5914	0.2327	0.1966	1.0045	-0.1967	1.016	-80.0798	56.4478	78.5594
179	0.1304	0.5868	-0.1836	2.453	-0.7899	0.2467	0.1984	0.0944	0.2081	0.0751	-0.1142	0.1754	-0.4049	-0.1016	-0.0608	1.2357	-0.0658	0.389	1.226	-0.427	1.317	-63.8133	78.6979	126.776
180	0.1075	0.1378	-0.0127	0.3299	0.2675	0.2431	0.0092	0.1962	-0.1254	0.1565	-0.0786	0.0523	0.1386	-0.2857	0.0075	0.5198	-0.3171	0.0678	0.9715	-0.3958	0.8963	-74.4564	-47.5848	56.1464
181	0.2673	0.2659	-0.0135	0.5849	0.0688	0.2181	0.0706	0.1014	-0.0704	0.0158	-0.092	0.0173	-0.0379	-0.1505	0.0576	0.3555	0.072	0.0524	0.5606	-0.1075	0.519	-35.7069	24.6352	74.3344
182	0.2118	0.0173	0.0049	0.1416	-0.0222	0.1484	0.0122	0.1454	-0.0011	-0.0592	0.0272	0.0156	0.0364	-0.0153	-0.038	0.3386	0.0001	-0.0456	0.2599	0.025	0.2476	139.1001	2.8578	220.1629
183	1.8867	-0.0801	-0.1327	0.0015	0.0058	0.0133	0.0244	-0.1652	-0.4586	0.2319	0.194	-1.0496	0.2106	1.0611	-0.1236	1.1824	0.2917	-0.2576	1.292	0.0438	1.4308	182.2887	-36.8244	297.9504
184	0.2312	0.1201	0.4046	0.73	0.1196	0.6853	0.1664	0.2472	0.0292	0.1081	-0.3087	-0.3005	0.1222	0.0862	0.2133	1.1102	-0.1794	0.0078	0.6564	0.1142	0.5995	153.9296	21.5133	329.0757
185	0.5489	0.0919	-0.2308	0.2367	-0.0106	0.0989	-0.1702	0.8299	0.4293	-0.6912	0.0819	0.0319	-0.4682	0.4797	0.1035	1.349	-0.0998	0.0788	1.4259	0.0781	0.8145	169.2371	-7.6292	145.2631
186	1.0112	-0.4065	-0.8535	1.7035	0.0102	0.8139	0.1517	-0.1317	0.0023	0.1883	-0.0215	-0.0884	0.2569	-0.0722	-0.0559	0.6919	-0.0765	0.0833	0.6067	0.0689	0.6349	204.6533	-10.9566	248.3189
187	0.0037	-0.0073	0.0048	0.0104	-0.0099	0.007	-0.0237	-0.1024	-0.7442	0.027	0.0595	-0.3536	0.747	0.4911	-0.0139	2.1547	0.1995	-0.0611	2.0838	-0.0273	2.0845	219.822	-35.4698	150.9354
188	1.4863	0.5033	-0.1632	0.7718	0.7079	0.9858	0.036	0.5846	0.3684	-0.6628	0.0394	0.5795	-0.232	-0.362	-0.0614	1.565	-0.0046	0.0203	1.4266	-0.3338	0.9677	191.2009	-13.6541	123.9551
189	0.063	0.005	-0.0434	0.009	-0.0144	0.0333	-0.041	0.3173	0.3252	-0.3696	0.1215	-0.0888	-0.4372	0.146	-0.0564	0.9826	-0.1354	0.2042	0.7787	0.5488	1.1347	186.3702	88.0875	195.7016
190	0.1862	-0.1672	0.1812	0.2148	-0.176	0.0859	-0.0872	-0.1381	-0.1536	0.4068	0.1718	0.0939	0.0346	-0.1056	-0.0929	0.647	0.0727	-0.0661	0.2899	0.0881	0.418	142.1109	-56.9009	289.859
191	0.2026	0.0068	-0.0229	0.1232	0.0188	0.323	0.0078	0.3298	0.0274	-0.2325	0.0851	0.0396	0.0287	-0.0293	-0.0369	0.6211	-0.0832	-0.0909	0.7396	0.0307	0.2943	127.6893	0.9763	165.1021
192	0.3302	-0.114	0.0118	0.6339	-0.0056	0.2039	-0.0328	-0.0047	0.2408	0.1665	-0.065	-0.3159	-0.165	0.0765	0.086	0.5356	-0.1061	-0.1107	0.3345	0.0852	0.6857	226.1806	68.6992	247.6363
193	1.5852	-0.8734	-1.2352	2.5752	-0.8548	2.0878	0.0235	-0.4815	0.4678	0.5044	-0.1539	-0.4465	-0.2991	0.5503	0.0206	1.2085	-0.1511	-0.348	0.4856	-0.1846	0.8891	213.8543	108.9433	272.1104
194	0.6416	0.4627	0.1116	1.8461	-0.3091	0.1189	0.1441	0.3183	0.399	-0.2667	0.0329	-0.2463	-0.4365	0.2465	-0.1322	1.8245	-0.1577	-0.1663	1.1865	0.2534	1.6832	221.194	131.3258	201.3147
195	0.0165	0.0275	0.0169	0.0466	0.035	0.0298	-0.0349	-0.0816	0.4054	-0.1304	-0.0283	-0.1081	-0.4193	0.0346	0.0148	2.4519	0.126	0.0846	2.5133	0.1091	2.532	241.2064	117.8483	191.1054
196	0.6081	-1.0426	0.2325	1.9986	-0.1306	0.3939	-0.1405	0.2546	-0.3028	-0.3341	-0.2071	-0.4988	0.4527	0.5253	0.1889	1.9555	0.1409	-0.5653	1.7476	-0.1126	1.675	277.3744	25.2172	296.6117
197	0.3082	-0.2296	0.1106	0.4238	0.1082	0.1725	-0.0768	-0.2411	0.1574	0.161	-0.0191	0.0143	-0.1156	0.1654	0.0437	1.0365	-0.1183	-0.4364	0.8075	-0.0365	0.957	247.1472	57.6117	291.6611
198	0.3978	0.0051	0.0913	0.5957	0.1683	0.2151	0.0516	0.2084	-0.0197	-0.1265	-0.1338	-0.3087	-0.0046	0.1312	0.0544	0.3499	0.0282	0.1441	0.4979	0.146	0.6321	243.1441	14.7218	209.4221
199	0.3642	-0.0788	0.6483	0.23	-0.3885	1.5073	-0.0268	-0.5536	0.1031	0.459	0.1435	-0.3455	-0.2357	0.6398	0.0008	1.65	-0.3341	0.0121	1.9816	0.2851	2.0572	290.2359	59.252	235.5464
200	0.507	0.2027	0.0177	0.8047	-0.0737	0.0082	0.0678	0.369	0.1258	-0.3141	0.0615	-0.1189	-0.1119	0.1319	-0.0447	2.1944	-0.2321	-0.0061	1.962	0.0779	1.9515	271.8456	89.3584	186.5157
201	0.4172	-0.0736	-0.5574	0.5299	0.2524	0.8651	0.1116	0.042	0.1099	0.0225	-0.1089	-0.1354	-0.3213	-0.1728	-0.0021	0.466	-0.1656	-0.0587	0.5351	0.2796	1.0734	254.9254	62.6943	238.0156
202	1.0094	-0.709	-0.2585	0.766	0.1234	0.5575	0.0331	-0.0304	0.2146	0.0588	0.0255	-0.1694	-0.2844	-0.1494	0.0482	1.2195	-0.093	0.1754	1.1957	0.4921	1.1282	248.7443	83.187	187.0939
203	-0.2289	-0.0565	0.192	0.9904	-0.3495	0.3128	-0.0548	-0.0354	-0.0342	0.4071	0.1795	0.0782	0.0587	-0.0387	0.0023	0.6802	0.159	0.2391	0.5219	0.2949	0.8119	248.1015	-40.4454	263.7378
204	0.4172	0.0518	-0.0839	0.3284	0.0159	0.3537	0.0386	0.0279	0.099	0.0218	-0.1005	0.0747	-0.1811	0.0038	0.0866	0.375	-0.0729	-0.0473	0.3658	0.0672	0.4222	207.9953	47.8936	234.5147

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth seq-ID	Auth asym-ID
1	X-RAY DIFFRACTION	1	segid S0A	0
2	X-RAY DIFFRACTION	2	segid S1A	0
3	X-RAY DIFFRACTION	3	segid S2A	0
4	X-RAY DIFFRACTION	4	segid S3A	0
5	X-RAY DIFFRACTION	5	segid S4A	0
6	X-RAY DIFFRACTION	6	segid S5A	0
7	X-RAY DIFFRACTION	7	segid S6A	0
8	X-RAY DIFFRACTION	8	segid S7A	0
9	X-RAY DIFFRACTION	9	segid S8A	0
10	X-RAY DIFFRACTION	10	segid S9A	0
11	X-RAY DIFFRACTION	11	segid S10A	1 - 96	0
12	X-RAY DIFFRACTION	12	segid S11A	2 - 156	1
13	X-RAY DIFFRACTION	13	segid S12A	20 - 143	2
14	X-RAY DIFFRACTION	14	segid S13A	2 - 151	3
15	X-RAY DIFFRACTION	15	segid S14A	11 - 137	4
16	X-RAY DIFFRACTION	16	segid S15A	8 - 131	5
17	X-RAY DIFFRACTION	17	segid S16A	3 - 143	6
18	X-RAY DIFFRACTION	18	segid S17A	2 - 126	7
19	X-RAY DIFFRACTION	19	segid S18A	2 - 146	8
20	X-RAY DIFFRACTION	20	segid S19A	2 - 144	9
21	X-RAY DIFFRACTION	21	segid S20A	15 - 121	0
22	X-RAY DIFFRACTION	22	segid S21A	1 - 87	1
23	X-RAY DIFFRACTION	23	segid S22A	2 - 130	2
24	X-RAY DIFFRACTION	24	segid S23A	2 - 145	3
25	X-RAY DIFFRACTION	25	segid S24A	2 - 135	4
26	X-RAY DIFFRACTION	26	segid S25A	36 - 105	5
27	X-RAY DIFFRACTION	27	segid S26A	2 - 500	6
28	X-RAY DIFFRACTION	28	segid S27A	2 - 101	7
29	X-RAY DIFFRACTION	29	segid S28A	5 - 67	8
30	X-RAY DIFFRACTION	30	segid S29A	4 - 99	9
31	X-RAY DIFFRACTION	31	segid S30A	2 - 61	0
32	X-RAY DIFFRACTION	32	segid S31A	82 - 501	1
33	X-RAY DIFFRACTION	33	segid SRKA	2 - 319	R
34	X-RAY DIFFRACTION	34	segid STMA	9 - 176	M
35	X-RAY DIFFRACTION	35	segid L2A	0
36	X-RAY DIFFRACTION	36	segid L3A	0
37	X-RAY DIFFRACTION	37	segid L4A	0
38	X-RAY DIFFRACTION	38	segid L5A	0
39	X-RAY DIFFRACTION	39	segid L6A	0
40	X-RAY DIFFRACTION	40	segid L7A	0
41	X-RAY DIFFRACTION	41	segid L8A	0
42	X-RAY DIFFRACTION	42	segid L9A	0
43	X-RAY DIFFRACTION	43	segid L10A	2 - 221	0
44	X-RAY DIFFRACTION	44	segid L11A	6 - 174	1
45	X-RAY DIFFRACTION	45	segid L13A	2 - 194	3
46	X-RAY DIFFRACTION	46	segid L14A	3 - 138	4
47	X-RAY DIFFRACTION	47	segid L15A	2 - 204	5
48	X-RAY DIFFRACTION	48	segid L16A	3 - 199	6
49	X-RAY DIFFRACTION	49	segid L17A	2 - 184	7
50	X-RAY DIFFRACTION	50	segid L18A	2 - 186	8
51	X-RAY DIFFRACTION	51	segid L19A and resid 2:73	2 - 73	9
52	X-RAY DIFFRACTION	52	segid L19A and resid 74:126	74 - 126	9
53	X-RAY DIFFRACTION	53	segid L19A and resid 127:183	127 - 183	9
54	X-RAY DIFFRACTION	54	segid L20A	1 - 172	0
55	X-RAY DIFFRACTION	55	segid L21A	2 - 160	1
56	X-RAY DIFFRACTION	56	segid L22A	9 - 108	2
57	X-RAY DIFFRACTION	57	segid L23A	2 - 137	3
58	X-RAY DIFFRACTION	58	segid L24A	1 - 98	4
59	X-RAY DIFFRACTION	59	segid L25A	22 - 142	5
60	X-RAY DIFFRACTION	60	segid L26A	2 - 127	6
61	X-RAY DIFFRACTION	61	segid L27A	2 - 136	7
62	X-RAY DIFFRACTION	62	segid L28A	2 - 149	8
63	X-RAY DIFFRACTION	63	segid L29A	2 - 59	9
64	X-RAY DIFFRACTION	64	segid L30A	9 - 105	0
65	X-RAY DIFFRACTION	65	segid L31A	4 - 112	1
66	X-RAY DIFFRACTION	66	segid L32A	2 - 128	2
67	X-RAY DIFFRACTION	67	segid L33A	2 - 107	3
68	X-RAY DIFFRACTION	68	segid L34A	2 - 113	4
69	X-RAY DIFFRACTION	69	segid L35A	2 - 120	5
70	X-RAY DIFFRACTION	70	segid L36A	2 - 100	6
71	X-RAY DIFFRACTION	71	segid L37A	2 - 100	7
72	X-RAY DIFFRACTION	72	segid L38A	2 - 78	8
73	X-RAY DIFFRACTION	73	segid L39A	2 - 51	9
74	X-RAY DIFFRACTION	74	segid L40A	77 - 500	0
75	X-RAY DIFFRACTION	75	segid L41A	1 - 25	1
76	X-RAY DIFFRACTION	76	segid L42A	2 - 501	2
77	X-RAY DIFFRACTION	77	segid L43A	2 - 501	3
78	X-RAY DIFFRACTION	78	segid S0B	0
79	X-RAY DIFFRACTION	79	segid S1B	0
80	X-RAY DIFFRACTION	80	segid S2B	0
81	X-RAY DIFFRACTION	81	segid S3B	0
82	X-RAY DIFFRACTION	82	segid S4B	0
83	X-RAY DIFFRACTION	83	segid S5B	0
84	X-RAY DIFFRACTION	84	segid S6B	0
85	X-RAY DIFFRACTION	85	segid S7B	0
86	X-RAY DIFFRACTION	86	segid S8B	0
87	X-RAY DIFFRACTION	87	segid S9B	0
88	X-RAY DIFFRACTION	88	segid S10B	1 - 98	0
89	X-RAY DIFFRACTION	89	segid S11B	2 - 147	1
90	X-RAY DIFFRACTION	90	segid S12B	20 - 143	2
91	X-RAY DIFFRACTION	91	segid S13B	2 - 151	3
92	X-RAY DIFFRACTION	92	segid S14B	10 - 137	4
93	X-RAY DIFFRACTION	93	segid S15B	4 - 138	5
94	X-RAY DIFFRACTION	94	segid S16B	2 - 143	6
95	X-RAY DIFFRACTION	95	segid S17B	2 - 122	7
96	X-RAY DIFFRACTION	96	segid S18B	2 - 146	8
97	X-RAY DIFFRACTION	97	segid S19B	2 - 144	9
98	X-RAY DIFFRACTION	98	segid S20B	12 - 121	0
99	X-RAY DIFFRACTION	99	segid S21B	1 - 87	1
100	X-RAY DIFFRACTION	100	segid S22B	2 - 130	2
101	X-RAY DIFFRACTION	101	segid S23B	2 - 145	3
102	X-RAY DIFFRACTION	102	segid S24B	2 - 135	4
103	X-RAY DIFFRACTION	103	segid S25B	37 - 105	5
104	X-RAY DIFFRACTION	104	segid S26B	2 - 500	6
105	X-RAY DIFFRACTION	105	segid S27B	2 - 1	7
106	X-RAY DIFFRACTION	106	segid S28B	5 - 67	8
107	X-RAY DIFFRACTION	107	segid S29B	4 - 99	9
108	X-RAY DIFFRACTION	108	segid S30B	2 - 63	0
109	X-RAY DIFFRACTION	109	segid S31B	77 - 501	1
110	X-RAY DIFFRACTION	110	segid SRKB	2 - 319	R
111	X-RAY DIFFRACTION	111	segid STMB	23 - 174	M
112	X-RAY DIFFRACTION	112	segid L2B	0
113	X-RAY DIFFRACTION	113	segid L3B	0
114	X-RAY DIFFRACTION	114	segid L4B	0
115	X-RAY DIFFRACTION	115	segid L5B	0
116	X-RAY DIFFRACTION	116	segid L6B	0
117	X-RAY DIFFRACTION	117	segid L7B	0
118	X-RAY DIFFRACTION	118	segid L8B	0
119	X-RAY DIFFRACTION	119	segid L9B	0
120	X-RAY DIFFRACTION	120	segid L10B	2 - 221	0
121	X-RAY DIFFRACTION	121	segid L11B	6 - 174	1
122	X-RAY DIFFRACTION	122	segid L12B	9 - 163	2
123	X-RAY DIFFRACTION	123	segid L13B	2 - 195	3
124	X-RAY DIFFRACTION	124	segid L14B	2 - 138	4
125	X-RAY DIFFRACTION	125	segid L15B	2 - 204	5
126	X-RAY DIFFRACTION	126	segid L16B	3 - 199	6
127	X-RAY DIFFRACTION	127	segid L17B	2 - 156	7
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