PDB-4u53: Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome

Basic information

• Entry: Database: PDB / ID: 4u53
• Title: Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome

Components

• (40S ribosomal protein ...) x 32
• (60S ribosomal protein ...) x 40
• (Unknown Protein ...) x 3
• 18S ribosomal RNA
• 25S ribosomal RNA
• 5.8S ribosomal RNA
• 5S ribosomal RNA
• 60S acidic ribosomal protein P0
• Guanine nucleotide-binding protein subunit beta-like protein
• Suppressor protein STM1
• Ubiquitin-40S ribosomal protein S31
• Ubiquitin-60S ribosomal protein L40

• Keywords: RIBOSOME / translation / 40S / 60S / 80S / eukaryote / RNA-protein complex / inhibitor / antibiotic

Function / homology

Function:

triplex DNA binding / ribosome hibernation / translation elongation factor binding / Platelet degranulation / regulation of translational initiation in response to stress / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / negative regulation of glucose mediated signaling pathway / negative regulation of translational frameshifting / Negative regulators of DDX58/IFIH1 signaling / RMTs methylate histone arginines / positive regulation of translational fidelity / Protein methylation / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / nonfunctional rRNA decay / hexon binding / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / pre-mRNA 5'-splice site binding / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / preribosome, small subunit precursor / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / Ribosomal scanning and start codon recognition / response to cycloheximide / telomeric DNA binding / Major pathway of rRNA processing in the nucleolus and cytosol / mRNA destabilization / SRP-dependent cotranslational protein targeting to membrane / GTP hydrolysis and joining of the 60S ribosomal subunit / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / Formation of a pool of free 40S subunits / negative regulation of mRNA splicing, via spliceosome / preribosome, large subunit precursor / regulation of amino acid metabolic process / L13a-mediated translational silencing of Ceruloplasmin expression / translational elongation / ribosomal large subunit export from nucleus / 90S preribosome / G-protein alpha-subunit binding / positive regulation of protein kinase activity / TOR signaling / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / regulation of translational fidelity / Ub-specific processing proteases / protein-RNA complex assembly / ribosomal subunit export from nucleus / ribosomal small subunit export from nucleus / translation regulator activity / translational termination / translation repressor activity / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / DNA-(apurinic or apyrimidinic site) endonuclease activity / maturation of LSU-rRNA / telomere maintenance / cellular response to amino acid starvation / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rescue of stalled ribosome / ribosome assembly / ribosomal large subunit biogenesis / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / translational initiation / macroautophagy / protein kinase C binding / maintenance of translational fidelity / modification-dependent protein catabolic process / cytoplasmic stress granule / protein tag activity / rRNA processing / ribosomal small subunit biogenesis / small ribosomal subunit rRNA binding / ribosome biogenesis / viral capsid / ribosome binding / ribosomal small subunit assembly / small ribosomal subunit / 5S rRNA binding / large ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / ribosomal large subunit assembly / cytoplasmic translation / cytosolic large ribosomal subunit / negative regulation of translation / rRNA binding / ribosome / protein ubiquitination / structural constituent of ribosome / positive regulation of protein phosphorylation / G protein-coupled receptor signaling pathway / translation / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / negative regulation of apoptotic process / host cell nucleus

Domain/homology:

Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / Pre-hexon-linking protein VIII / Adenovirus hexon associated protein, protein VIII / 50S ribosomal protein L10, insertion domain superfamily / : / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal protein 60S L18 and 50S L18e / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S26e / Ribosomal protein S21e, conserved site / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S21e signature. / : / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / Small (40S) ribosomal subunit Asc1/RACK1 / S27a-like superfamily / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / 40S Ribosomal protein S10 / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L44e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L10e / Ribosomal protein L13e / Ribosomal protein S27a / Ribosomal protein L13e / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein L19, eukaryotic / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein S17e, conserved site / Ribosomal protein S17e signature. / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S30 / : / Ribosomal protein S30 / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein S7e signature. / : / Ribosomal protein L24e, conserved site / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L24e signature. / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / : / Ribosomal protein S19e / Ribosomal protein S3Ae, conserved site / Ribosomal protein S19e / Ribosomal protein L30e signature 1. / Ribosomal protein L6e signature. / Ribosomal protein S3Ae signature. / Ribosomal_S19e / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein S27e signature. / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal L40e family / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein S4e, N-terminal, conserved site / Ribosomal protein S4e signature.

Component:

Chem-3J6 / osmium (III) hexammine / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / : / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein uS11A / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Pre-hexon-linking protein VIII / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Small ribosomal subunit protein eS32A / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A

• Biological species: Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.3 Å
• Authors: Garreau de Loubresse, N. / Prokhorova, I. / Yusupova, G. / Yusupov, M.
• Citation: Journal: Nature / Year: 2014; Title: Structural basis for the inhibition of the eukaryotic ribosome.; Authors: Garreau de Loubresse, N. / Prokhorova, I. / Holtkamp, W. / Rodnina, M.V. / Yusupova, G. / Yusupov, M.

History

Deposition	Jul 24, 2014	Deposition site: RCSB / Processing site: PDBE
Revision 1.0	Oct 22, 2014	Provider: repository / Type: Initial release
Supersession	Dec 10, 2014	ID: 4ukp, 4ukq, 4ukr, 4uks, 4ukt
Revision 1.1	Dec 10, 2014	Group: Other
Revision 1.2	Dec 17, 2014	Group: Other
Revision 1.3	Jan 20, 2016	Group: Structure summary
Revision 1.4	Dec 20, 2023	Group: Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_conn_type Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id

Assembly

Deposited unit

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m2: Unknown Protein m2

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

p1: Unknown Protein p1

p2: Unknown Protein p2

hetero molecules

Summary:

• 6.63 MDa, 162 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	6,630,579	2716
Polymers	6,271,175	162
Non-polymers	359,404	2554
Water	0	0

1

2: 18S ribosomal RNA

S0: 40S ribosomal protein S0-A

S1: 40S ribosomal protein S1-A

S2: 40S ribosomal protein S2

S3: 40S ribosomal protein S3

S4: 40S ribosomal protein S4-A

S5: 40S ribosomal protein S5

S6: 40S ribosomal protein S6-A

S7: 40S ribosomal protein S7-A

S8: 40S ribosomal protein S8-A

S9: 40S ribosomal protein S9-A

C0: 40S ribosomal protein S10-A

C1: 40S ribosomal protein S11-A

C2: 40S ribosomal protein S12

C3: 40S ribosomal protein S13

C4: 40S ribosomal protein S14-A

C5: 40S ribosomal protein S15

C6: 40S ribosomal protein S16-A

C7: 40S ribosomal protein S17-A

C8: 40S ribosomal protein S18-A

C9: 40S ribosomal protein S19-A

D0: 40S ribosomal protein S20

D1: 40S ribosomal protein S21-A

D2: 40S ribosomal protein S22-A

D3: 40S ribosomal protein S23-A

D4: 40S ribosomal protein S24-A

D5: 40S ribosomal protein S25-A

D6: 40S ribosomal protein S26-B

D7: 40S ribosomal protein S27-A

D8: 40S ribosomal protein S28-A

D9: 40S ribosomal protein S29-A

E0: 40S ribosomal protein S30-A

E1: Ubiquitin-40S ribosomal protein S31

SR: Guanine nucleotide-binding protein subunit beta-like protein

SM: Suppressor protein STM1

1: 25S ribosomal RNA

3: 5S ribosomal RNA

4: 5.8S ribosomal RNA

L2: 60S ribosomal protein L2-A

L3: 60S ribosomal protein L3

L4: 60S ribosomal protein L4-A

L5: 60S ribosomal protein L5

L6: 60S ribosomal protein L6-A

L7: 60S ribosomal protein L7-A

L8: 60S ribosomal protein L8-A

L9: 60S ribosomal protein L9-A

M0: 60S ribosomal protein L10

M1: 60S ribosomal protein L11-B

M3: 60S ribosomal protein L13-A

M4: 60S ribosomal protein L14-A

M5: 60S ribosomal protein L15-A

M6: 60S ribosomal protein L16-A

M7: 60S ribosomal protein L17-A

M8: 60S ribosomal protein L18-A

M9: 60S ribosomal protein L19-A

N0: 60S ribosomal protein L20-A

N1: 60S ribosomal protein L21-A

N2: 60S ribosomal protein L22-A

N3: 60S ribosomal protein L23-A

N4: 60S ribosomal protein L24-A

N5: 60S ribosomal protein L25

N6: 60S ribosomal protein L26-A

N7: 60S ribosomal protein L27-A

N8: 60S ribosomal protein L28

N9: 60S ribosomal protein L29

O0: 60S ribosomal protein L30

O1: 60S ribosomal protein L31-A

O2: 60S ribosomal protein L32

O3: 60S ribosomal protein L33-A

O4: 60S ribosomal protein L34-A

O5: 60S ribosomal protein L35-A

O6: 60S ribosomal protein L36-A

O7: 60S ribosomal protein L37-A

O8: 60S ribosomal protein L38

O9: 60S ribosomal protein L39

Q0: Ubiquitin-60S ribosomal protein L40

Q1: 60S ribosomal protein L41-A

Q2: 60S ribosomal protein L42-A

Q3: 60S ribosomal protein L43-A

hetero molecules

Summary:

• defined by author
• 3.28 MDa, 79 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,284,341	1320
Polymers	3,107,872	79
Non-polymers	176,469	1241
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

6: 18S ribosomal RNA

s0: 40S ribosomal protein S0-A

s1: 40S ribosomal protein S1-A

s2: 40S ribosomal protein S2

s3: 40S ribosomal protein S3

s4: 40S ribosomal protein S4-A

s5: 40S ribosomal protein S5

s6: 40S ribosomal protein S6-A

s7: 40S ribosomal protein S7-A

s8: 40S ribosomal protein S8-A

s9: 40S ribosomal protein S9-A

c0: 40S ribosomal protein S10-A

c1: 40S ribosomal protein S11-A

c2: 40S ribosomal protein S12

c3: 40S ribosomal protein S13

c4: 40S ribosomal protein S14-A

c5: 40S ribosomal protein S15

c6: 40S ribosomal protein S16-A

c7: 40S ribosomal protein S17-A

c8: 40S ribosomal protein S18-A

c9: 40S ribosomal protein S19-A

d0: 40S ribosomal protein S20

d1: 40S ribosomal protein S21-A

d2: 40S ribosomal protein S22-A

d3: 40S ribosomal protein S23-A

d4: 40S ribosomal protein S24-A

d5: 40S ribosomal protein S25-A

d6: 40S ribosomal protein S26-B

d7: 40S ribosomal protein S27-A

d8: 40S ribosomal protein S28-A

d9: 40S ribosomal protein S29-A

e0: 40S ribosomal protein S30-A

e1: Ubiquitin-40S ribosomal protein S31

sR: Guanine nucleotide-binding protein subunit beta-like protein

sM: Suppressor protein STM1

5: 25S ribosomal RNA

7: 5S ribosomal RNA

8: 5.8S ribosomal RNA

l2: 60S ribosomal protein L2-A

l3: 60S ribosomal protein L3

l4: 60S ribosomal protein L4-A

l5: 60S ribosomal protein L5

l6: 60S ribosomal protein L6-A

l7: 60S ribosomal protein L7-A

l8: 60S ribosomal protein L8-A

l9: 60S ribosomal protein L9-A

m0: 60S ribosomal protein L10

m1: 60S ribosomal protein L11-B

m2: Unknown Protein m2

m3: 60S ribosomal protein L13-A

m4: 60S ribosomal protein L14-A

m5: 60S ribosomal protein L15-A

m6: 60S ribosomal protein L16-A

m7: 60S ribosomal protein L17-A

m8: 60S ribosomal protein L18-A

m9: 60S ribosomal protein L19-A

n0: 60S ribosomal protein L20-A

n1: 60S ribosomal protein L21-A

n2: 60S ribosomal protein L22-A

n3: 60S ribosomal protein L23-A

n4: 60S ribosomal protein L24-A

n5: 60S ribosomal protein L25

n6: 60S ribosomal protein L26-A

n7: 60S ribosomal protein L27-A

n8: 60S ribosomal protein L28

n9: 60S ribosomal protein L29

o0: 60S ribosomal protein L30

o1: 60S ribosomal protein L31-A

o2: 60S ribosomal protein L32

o3: 60S ribosomal protein L33-A

o4: 60S ribosomal protein L34-A

o5: 60S ribosomal protein L35-A

o6: 60S ribosomal protein L36-A

o7: 60S ribosomal protein L37-A

o8: 60S ribosomal protein L38

o9: 60S ribosomal protein L39

q0: Ubiquitin-60S ribosomal protein L40

q1: 60S ribosomal protein L41-A

q2: 60S ribosomal protein L42-A

q3: 60S ribosomal protein L43-A

p0: 60S acidic ribosomal protein P0

p1: Unknown Protein p1

p2: Unknown Protein p2

hetero molecules

Summary:

• defined by author
• 3.35 MDa, 83 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	3,346,238	1396
Polymers	3,163,303	83
Non-polymers	182,936	1313
Water	0

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	435.840, 286.770, 303.770
Angle α, β, γ (deg.)	90.000, 99.030, 90.000
Int Tables number	4
Space group name H-M	P1211

• Details: there are 2 biological units in the asymetric unit (segid *A and segid *B)

Components

RNA chain , 4 types, 8 molecules 2 6 1 5 3 7 4 8

#1: RNA chain

2 6 18S ribosomal RNA / RNA (1750-MER)

Details:

Mass: 579761.938 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 1262303

#36: RNA chain

1 5 25S ribosomal RNA / RNA (3149-MER)

Details:

Mass: 1097493.875 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#37: RNA chain

3 7 5S ribosomal RNA / RNA (121-MER)

Details:

Mass: 38951.105 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: TPG: 329138943

#38: RNA chain

4 8 5.8S ribosomal RNA / RNA (158-MER)

Details:

Mass: 50682.922 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: GenBank: 618731124

40S ribosomal protein ... , 32 types, 62 molecules S0 s0 S1 s1 S2 s2 S3 s3 S4 s4 S5 s5 S6 s6 S7 s7 S8 s8 S9 s9 C0 c0 C1 c1 C2 c2 C3 c3 C4 c4 ...

#2: Protein

S0 s0 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A

Details:

Mass: 27920.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P32905

#3: Protein

S1 s1 40S ribosomal protein S1-A / RP10A

Details:

Mass: 28667.275 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P33442

#4: Protein

S2 s2 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / YS5

Details:

Mass: 27359.629 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P25443

#5: Protein

S3 s3 40S ribosomal protein S3 / RP13 / YS3

Details:

Mass: 26411.596 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05750

#6: Protein

S4 s4 40S ribosomal protein S4-A / RP5 / S7 / YS6

Details:

Mass: 29338.133 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX35

#7: Protein

S5 s5 40S ribosomal protein S5 / RP14 / S2 / YS8

Details:

Mass: 24941.402 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26783

#8: Protein

S6 s6 40S ribosomal protein S6-A / RP9 / S10 / YS4

Details:

Mass: 27054.486 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX37

#9: Protein

S7 s7 40S ribosomal protein S7-A / RP30 / RP40

Details:

Mass: 21527.014 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26786

#10: Protein

S8 s8 40S ribosomal protein S8-A / RP19 / S14 / YS9

Details:

Mass: 22537.803 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX39

#11: Protein

S9 s9 40S ribosomal protein S9-A / RP21 / S13 / YP28 / YS11

Details:

Mass: 22356.695 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: O13516

#12: Protein

C0 c0 40S ribosomal protein S10-A

Details:

Mass: 12771.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q08745

#13: Protein

C1 c1 40S ribosomal protein S11-A / RP41 / S18 / YS12

Details:

Mass: 17668.766 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX47

#14: Protein

C2 c2 40S ribosomal protein S12

Details:

Mass: 15385.485 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P48589

#15: Protein

C3 c3 40S ribosomal protein S13 / S27a / YS15

Details:

Mass: 16928.748 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05756

#16: Protein

C4 c4 40S ribosomal protein S14-A / RP59A

Details:

Mass: 14431.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P06367

#17: Protein

C5 c5 40S ribosomal protein S15 / RIG protein / RP52 / S21 / YS21

Details:

Mass: 15900.712 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q01855

#18: Protein

C6 c6 40S ribosomal protein S16-A / RP61R

Details:

Mass: 15746.292 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX51

#19: Protein

C7 c7 40S ribosomal protein S17-A / RP51A

Details:

Mass: 15820.413 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02407

#20: Protein

C8 c8 40S ribosomal protein S18-A

Details:

Mass: 16940.443 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX55

#21: Protein

C9 c9 40S ribosomal protein S19-A / RP55A / S16a / YP45 / YS16A

Details:

Mass: 15810.930 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P07280

#22: Protein

D0 d0 40S ribosomal protein S20

Details:

Mass: 13797.850 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38701

#23: Protein

D1 d1 40S ribosomal protein S21-A / S26 / YS25

Details:

Mass: 9758.829 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0V8

#24: Protein

D2 d2 40S ribosomal protein S22-A / RP50 / S24 / YP58 / YS22

Details:

Mass: 14518.867 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C0W1

#25: Protein

D3 d3 40S ribosomal protein S23-A / RP37 / S28 / YS14

Details:

Mass: 15942.699 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX29

#26: Protein

D4 d4 40S ribosomal protein S24-A / RP50

Details:

Mass: 15231.650 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX31

#27: Protein

D5 d5 40S ribosomal protein S25-A / RP45 / S31 / YS23

Details:

Mass: 11936.076 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E792

#28: Protein

D6 d6 40S ribosomal protein S26-B

Details:

Mass: 11022.989 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39939

#29: Protein

D7 d7 40S ribosomal protein S27-A / RP61 / YS20

Details:

Mass: 8762.195 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P35997

#30: Protein

D8 d8 40S ribosomal protein S28-A / S33 / YS27

Details:

Mass: 7474.652 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E7X9

#31: Protein

D9 d9 40S ribosomal protein S29-A / S36 / YS29

Details:

Mass: 6544.527 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41057

#32: Protein

E0 40S ribosomal protein S30-A

Details:

Mass: 6779.086 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

#80: Protein

e0 40S ribosomal protein S30-A

Details:

Mass: 7006.346 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX33

Protein , 5 types, 9 molecules E1 e1 SR sR SM sM Q0 q0 p0

#33: Protein

E1 e1 Ubiquitin-40S ribosomal protein S31

Details:

Mass: 8703.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05759

#34: Protein

SR sR Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1

Details:

Mass: 34710.023 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38011

#35: Protein

SM sM Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1

Details:

Mass: 30048.010 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P39015

#76: Protein

Q0 q0 Ubiquitin-60S ribosomal protein L40

Details:

Mass: 6032.321 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CH08

#82: Protein

p0 60S acidic ribosomal protein P0 / A0 / L10E

Details:

Mass: 33617.930 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05317

60S ribosomal protein ... , 40 types, 80 molecules L2 l2 L3 l3 L4 l4 L5 l5 L6 l6 L7 l7 L8 l8 L9 l9 M0 m0 M1 m1 M3 m3 M4 m4 M5 m5 M6 m6 M7 m7 ...

#39: Protein

L2 l2 60S ribosomal protein L2-A / L5 / RP8 / YL6

Details:

Mass: 27332.377 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX45

#40: Protein

L3 l3 60S ribosomal protein L3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1

Details:

Mass: 43719.602 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14126

#41: Protein

L4 l4 60S ribosomal protein L4-A / L2 / RP2 / YL2

Details:

Mass: 39027.926 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P10664

#42: Protein

L5 l5 60S ribosomal protein L5 / L1 / L1a / Ribosomal 5S RNA-binding protein / YL3

Details:

Mass: 33633.633 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26321

#43: Protein

L6 l6 60S ribosomal protein L6-A / L17 / RP18 / YL16

Details:

Mass: 19869.369 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02326

#44: Protein

L7 l7 60S ribosomal protein L7-A / L6 / RP11 / YL8

Details:

Mass: 27555.084 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05737

#45: Protein

L8 l8 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Maintenance of killer protein 7 / RP6 / YL5

Details:

Mass: 28044.621 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P17076

#46: Protein

L9 l9 60S ribosomal protein L9-A / L8 / RP24 / YL11

Details:

Mass: 21605.061 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05738

#47: Protein

M0 m0 60S ribosomal protein L10 / L9 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein

Details:

Mass: 25279.271 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P41805

#48: Protein

M1 m1 60S ribosomal protein L11-B / L16 / RP39 / YL22

Details:

Mass: 19654.520 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q3E757

#49: Protein

M3 m3 60S ribosomal protein L13-A

Details:

Mass: 22472.967 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q12690

#50: Protein

M4 m4 60S ribosomal protein L14-A

Details:

Mass: 15063.870 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P36105

#51: Protein

M5 m5 60S ribosomal protein L15-A / L13 / RP15R / YL10 / YP18

Details:

Mass: 24351.162 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05748

#52: Protein

M6 m6 60S ribosomal protein L16-A / L13a / L21 / RP22 / YL15

Details:

Mass: 22116.029 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P26784

#53: Protein

M7 m7 60S ribosomal protein L17-A / L20A / YL17

Details:

Mass: 20458.322 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05740

#54: Protein

M8 m8 60S ribosomal protein L18-A / RP28

Details:

Mass: 20478.059 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX49

#55: Protein

M9 m9 60S ribosomal protein L19-A / L23 / RP15L / RP33 / YL14

Details:

Mass: 21631.121 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX82

#56: Protein

N0 n0 60S ribosomal protein L20-A / L18a

Details:

Mass: 20478.852 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX23

#57: Protein

N1 n1 60S ribosomal protein L21-A

Details:

Mass: 18148.066 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: Q02753

#58: Protein

N2 n2 60S ribosomal protein L22-A / L1c / RP4 / YL31

Details:

Mass: 13580.163 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05749

#59: Protein

N3 n3 60S ribosomal protein L23-A / L17a / YL32

Details:

Mass: 14362.755 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX41

#60: Protein

N4 n4 60S ribosomal protein L24-A / L30 / RP29 / YL21

Details:

Mass: 17661.717 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04449

#61: Protein

N5 n5 60S ribosomal protein L25 / RP16L / YL25 / YP42'

Details:

Mass: 15656.417 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04456

#62: Protein

N6 n6 60S ribosomal protein L26-A / L33 / YL33

Details:

Mass: 14134.588 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05743

#63: Protein

N7 n7 60S ribosomal protein L27-A

Details:

Mass: 15437.166 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H6

#64: Protein

N8 n8 60S ribosomal protein L28 / L27a / L29 / RP44 / RP62 / YL24

Details:

Mass: 16630.471 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P02406

#65: Protein

N9 n9 60S ribosomal protein L29 / YL43

Details:

Mass: 6560.688 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05747

#66: Protein

O0 o0 60S ribosomal protein L30 / L32 / RP73 / YL38

Details:

Mass: 11299.168 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P14120

#67: Protein

O1 o1 60S ribosomal protein L31-A / L34 / YL28

Details:

Mass: 12848.962 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0C2H8

#68: Protein

O2 o2 60S ribosomal protein L32

Details:

Mass: 14678.246 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P38061

#69: Protein

O3 o3 60S ribosomal protein L33-A / L37 / RP47 / YL37

Details:

Mass: 12045.935 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05744

#70: Protein

O4 o4 60S ribosomal protein L34-A

Details:

Mass: 13412.820 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P87262

#71: Protein

O5 o5 60S ribosomal protein L35-A

Details:

Mass: 13811.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX84

#72: Protein

O6 o6 60S ribosomal protein L36-A / L39 / YL39

Details:

Mass: 11020.063 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P05745

#73: Protein

O7 o7 60S ribosomal protein L37-A / L43 / YL35 / YP55

Details:

Mass: 9746.199 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49166

#74: Protein

O8 o8 60S ribosomal protein L38

Details:

Mass: 8714.363 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P49167

#75: Protein/peptide

O9 o9 60S ribosomal protein L39 / L46 / YL40

Details:

Mass: 6227.444 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P04650

#77: Protein/peptide

Q1 q1 60S ribosomal protein L41-A / L47 / YL41

Details:

Mass: 3354.243 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX86

#78: Protein

Q2 q2 60S ribosomal protein L42-A / L41 / YL27 / YP44

Details:

Mass: 12115.462 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX27

#79: Protein

Q3 q3 60S ribosomal protein L43-A / L37a / YL35

Details:

Mass: 9981.756 Da / Num. of mol.: 2 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)
References: UniProt: P0CX25

Unknown Protein ... , 3 types, 3 molecules m2 p1 p2

#81: Protein

m2 Unknown Protein m2

Details:

Mass: 13634.798 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#83: Protein/peptide

p1 Unknown Protein p1

Details:

Mass: 4017.944 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

#84: Protein/peptide

p2 Unknown Protein p2

Details:

Mass: 3932.839 Da / Num. of mol.: 1 / Source method: isolated from a natural source
Source: (natural) Saccharomyces cerevisiae ATCC 204508 / S288c (yeast)

Non-polymers , 4 types, 2554 molecules

#85: Chemical

2-1901 2-1902 2-1903 2-1904 2-1905 2-1906 2-1907 2-1908 2-1909 2-1910 2-1911 2-1912 2-1913 2-1914 2-1915 2-1916 2-1917 2-1918 2-1919 2-1920 ...
ChemComp-MG / MAGNESIUM ION

Details:

Mass: 24.305 Da / Num. of mol.: 1406 / Source method: isolated from a natural source / Formula: Mg

#86: Chemical

2-2023 2-2024 2-2025 2-2026 2-2027 2-2028 2-2029 2-2030 2-2031 2-2032 2-2033 2-2034 2-2035 2-2036 2-2037 2-2038 2-2039 2-2040 2-2041 2-2042 ...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide

Details:

Mass: 286.365 Da / Num. of mol.: 1130 / Source method: isolated from a natural source / Formula: H₁₂N₆Os

#87: Chemical

D6-500 D7-101 D9-101 E1-501 O7-101 Q0-500 Q2-501 Q3-501 d6-101 d7-101 d9-101 e1-501 o7-501 q0-201 q2-501 q3-501
ChemComp-ZN / ZINC ION

Details:

Mass: 65.409 Da / Num. of mol.: 16 / Source method: isolated from a natural source / Formula: Zn

#88: Chemical

1-4213 5-4246 ChemComp-3J6 / (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one

Details:

Mass: 296.316 Da / Num. of mol.: 2 / Source method: isolated from a natural source / Formula: C₁₅H₂₀O₆ / Comment: toxin*YM

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 3.05 ų/Da / Density % sol: 59.7 %
• Crystal grow: Temperature: 277 K / Method: vapor diffusion, hanging drop / pH: 7.5 ; Details: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: SOLEIL / Beamline: PROXIMA 1 / Wavelength: 1 Å
• Detector: Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Jul 1, 2013
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 1 Å / Relative weight: 1
• Reflection: Resolution: 3.3→49.702 Å / Num. obs: 1095552 / % possible obs: 99.4 % / Observed criterion σ(I): -3 / Redundancy: 5.73 % / B_iso Wilson estimate: 90.07 Ų / R_merge F obs: 0.986 / R_merge(I) obs: 0.312 / R_rim(I) all: 0.341 / Χ²: 0.944 / Net I/σ(I): 5.8 / Num. measured all: 6419636

Reflection shell

Diffraction-ID: 1 / Rejects: _

Resolution (Å)	Highest resolution (Å)	Rmerge F obs	Rmerge(I) obs	Mean I/σ(I) obs	Num. measured obs	Num. possible	Num. unique obs	Rrim(I) all	% possible all
3.3-3.4		0.372	1.916	0.99	533947	94070	93228	2.103	99.1
3.4-3.5		0.489	1.525	1.27	496005	83785	83100	1.666	99.2
3.5-3.6		0.591	1.214	1.6	443584	74666	74079	1.326	99.2
3.6-3.8		0.713	0.907	2.14	727810	126824	125933	0.994	99.3
3.8-4		0.836	0.634	3.09	608381	102771	102139	0.692	99.4
4-4.5		0.917	0.42	4.58	1074808	184002	183088	0.46	99.5
4.5-5		0.959	0.281	6.72	682255	117694	117159	0.307	99.5
5-6		0.975	0.21	8.83	788588	133645	133163	0.229	99.6
6-7		0.982	0.173	10.44	397289	68046	67839	0.189	99.7
7-8		0.988	0.138	13.22	226118	38322	38222	0.151	99.7
8-9		0.99	0.118	14.93	128880	23155	23096	0.13	99.7
9-10		0.993	0.105	17.48	88571	14838	14807	0.114	99.8
10-20		0.995	0.083	20.42	197955	35127	35003	0.091	99.6
20-30		0.995	0.058	26.19	20378	3615	3583	0.064	99.1
30-40		0.995	0.055	26.26	4387	882	861	0.061	97.6
	40	0.99	0.076	9.9	680	679	252	0.093	37.1

Processing

Software

Name	Version	Classification
XDS		data reduction
PHENIX	(phenix.refine: dev_1702)	refinement
PDB_EXTRACT	3.14	data extraction
XSCALE		data scaling
XSCALE		data reduction

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 3U5B, 3U5C, 3U5D, 3U5E, 3U5F, 3U5G, 3U5H, 3U5I

3u5b
PDB Unreleased entry

3u5c
PDB Unreleased entry

3u5d
PDB Unreleased entry

3u5e
PDB Unreleased entry

3u5f
PDB Unreleased entry

3u5g
PDB Unreleased entry

3u5h
PDB Unreleased entry

3u5i
PDB Unreleased entry

Resolution: 3.3→49.702 Å / SU ML: 0.44 / Cross valid method: FREE R-VALUE / σ(F): 0 / Phase error: 24.64 / Stereochemistry target values: ML

	Rfactor	Num. reflection	% reflection
Rfree	0.2553	21905	2 %
Rwork	0.2016	1073376	-
obs	0.2027	1095281	99.42 %

• Solvent computation: Shrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
• Displacement parameters: B_iso max: 299.51 Ų / B_iso mean: 79.0567 Ų / B_iso min: 17.14 Ų

Refinement step

Cycle: final / Resolution: 3.3→49.702 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	179693	222116	10954	0	412763
Biso mean	-	-	125.97	-	-
Num. residues	-	-	-	-	32990

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.012	438169
X-RAY DIFFRACTION	f_angle_d	1.576	650191
X-RAY DIFFRACTION	f_chiral_restr	0.063	79432
X-RAY DIFFRACTION	f_plane_restr	0.007	41786
X-RAY DIFFRACTION	f_dihedral_angle_d	19.126	194786

LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection all	% reflection obs (%)
3.3-3.3375	0.3403	725	0.2991	35543	36268	99
3.3375-3.3767	0.3346	725	0.2854	35522	36247	99
3.3767-3.4179	0.3232	726	0.2737	35555	36281	99
3.4179-3.4612	0.3144	727	0.2667	35629	36356	99
3.4612-3.5067	0.321	727	0.2608	35610	36337	99
3.5067-3.5547	0.2904	726	0.2449	35577	36303	99
3.5547-3.6055	0.3031	728	0.2452	35674	36402	99
3.6055-3.6593	0.2897	728	0.2264	35649	36377	99
3.6593-3.7165	0.2768	727	0.2226	35632	36359	99
3.7165-3.7774	0.2714	729	0.2153	35707	36436	99
3.7774-3.8425	0.2665	727	0.21	35651	36378	99
3.8425-3.9123	0.2836	729	0.2049	35719	36448	99
3.9123-3.9875	0.2624	729	0.1962	35747	36476	99
3.9875-4.0689	0.2516	729	0.1893	35683	36412	99
4.0689-4.1573	0.2511	731	0.1847	35816	36547	99
4.1573-4.254	0.2468	727	0.1823	35669	36396	100
4.254-4.3603	0.2174	732	0.1746	35867	36599	100
4.3603-4.4781	0.2275	732	0.1724	35815	36547	100
4.4781-4.6098	0.2389	729	0.1783	35739	36468	100
4.6098-4.7585	0.2292	731	0.1701	35826	36557	100
4.7585-4.9284	0.2287	731	0.171	35809	36540	100
4.9284-5.1256	0.2213	733	0.1708	35904	36637	100
5.1256-5.3586	0.2225	731	0.1695	35866	36597	100
5.3586-5.6407	0.2455	733	0.1748	35931	36664	100
5.6407-5.9936	0.2378	734	0.1804	35908	36642	100
5.9936-6.4554	0.2538	734	0.1911	35975	36709	100
6.4554-7.1034	0.2407	734	0.1884	35964	36698	100
7.1034-8.1274	0.2528	736	0.2014	36051	36787	100
8.1274-10.225	0.2607	738	0.2125	36193	36931	100
10.225-49.7077	0.252	737	0.231	36145	36882	99

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	1.0362	-0.0953	-0.7047	0.6514	0.2969	1.8731	0.0729	-0.0252	-0.3972	0.2967	-0.0927	0.0092	0.3018	-0.0059	-0.0087	0.7814	-0.4137	0.4784	1.2029	-0.3782	1.3141	-110.6709	-8.1122	109.9028
2	0.5835	-0.5016	0.2234	0.6323	0.0924	0.4309	-0.0548	-0.3137	-0.4756	0.6107	-0.0641	-0.0001	0.3676	-0.1487	0.1469	1.5453	-0.3429	0.0363	1.0921	0.3045	1.0112	-46.9958	-27.7343	138.7377
3	0.9999	0.1763	-0.1897	0.5658	0.1148	1.0561	0.0182	0.1858	0.0606	-0.0697	-0.0928	0.571	0.0381	-0.5487	0.0363	0.5354	-0.0652	-0.0251	1.0805	-0.2914	1.1462	-101.0236	9.7484	76.7395
4	0.3519	0.3229	-0.0172	0.6868	-0.0466	0.6681	-0.0175	0.205	0.0308	0.0785	0.1683	0.2265	-0.181	-0.1711	-0.1087	0.502	-0.1398	-0.0415	1.2453	-0.3235	1.0166	-99.5425	-28.9826	45.7185
5	0.6757	-0.054	-0.2917	0.9279	0.2145	0.9854	-0.0158	-0.0337	0.3495	-0.0051	0.0579	0.3847	-0.214	-0.3008	-0.0767	0.7362	0.329	0.0226	1.0271	0.0163	1.1876	-79.8529	81.1893	71.118
6	1.0039	-0.6309	0.2748	0.4134	0.0304	1.6775	-0.1088	-0.2622	-0.228	0.1988	-0.0239	-0.0412	0.3538	-0.0015	0.0798	1.2289	-0.347	0.0034	0.6849	-0.1526	0.9704	-76.4616	-76.8638	90.5061
7	0.5204	0.0522	-0.398	0.6092	-0.0549	0.4994	-0.0747	0.1119	0.2324	-0.3987	-0.1071	-0.2195	-0.2392	0.0437	0.1539	0.8463	0.2068	-0.0072	0.7434	0.1916	0.9866	-29.942	98.1362	48.7297
8	1.048	-0.2285	-0.6197	0.5845	-0.1673	0.6096	-0.0203	-0.4093	0.235	0.1393	-0.2203	0.0491	-0.1283	-0.0758	-0.0221	0.85	-0.045	0.3938	1.2138	-0.6107	1.0471	-97.6216	47.8967	136.123
9	0.6748	-0.0137	-0.0442	1.7587	0.4112	0.7941	0.0086	-0.1751	0.3194	0.3875	0.0987	-0.005	-0.1479	0.0273	-0.1694	0.6575	0.0729	0.1218	0.607	-0.168	0.7475	-31.4675	89.0175	94.6505
10	0.6606	-0.0165	-0.0013	0.7862	0.2804	1.0254	0.1806	0.0933	0.0372	-0.1971	0.0415	0.2833	-0.1315	-0.2269	-0.2398	0.5767	0.105	-0.1922	1.3651	-0.1357	1.4693	-96.4586	41.6683	48.2899
11	0.1953	-0.5488	0.3724	1.7278	-0.5191	2.1009	0.1295	0.3638	-0.1104	-0.2943	0.0585	-0.0192	-0.0625	-0.1083	-0.2453	0.7894	-0.3375	-0.0341	1.4377	-0.1113	1.0518	-86.5884	-32.7364	13.8491
12	1.2856	0.807	0.005	1.6276	0.266	0.4607	0.1992	-0.3171	0.0099	0.3187	-0.3391	0.1386	-0.1063	-0.0323	0.1099	0.7435	0.0819	0.2048	0.8315	-0.1261	0.6783	-52.2352	67.0409	104.7733
13	2.4149	-1.1795	-0.1042	1.6627	-0.9785	0.9878	0.0827	-0.0247	0.0627	-0.0065	-0.0085	0.1231	0.0092	-0.1039	-0.0389	1.5053	-0.2617	-0.0459	1.8386	-0.0148	1.1715	-79.3728	-25.5561	-18.2693
14	1.0828	-0.2983	-0.7256	0.8157	0.3148	1.1887	0.0845	-0.3004	0.1731	0.5218	-0.0946	0.1794	-0.1837	-0.2282	-0.1222	0.856	-0.2497	0.2064	1.1435	-0.1865	0.6658	-60.5554	30.0837	131.6466
15	0.0977	-0.177	0.0427	0.3989	-0.08	0.0151	0.0411	-0.1155	-0.3415	0.3636	-0.1158	-0.1432	0.1964	-0.054	0.0818	1.193	-0.3171	-0.0986	0.7398	0.2961	1.4134	-44.8231	-39.4625	115.6282
16	1.0523	0.3566	-0.4863	2.2522	0.1139	1.7209	-0.0201	-0.0056	-0.0487	-0.3434	-0.1473	-0.043	0.3086	-0.0674	0.1871	0.5008	-0.0995	0.1849	0.9771	-0.4574	1.0793	-46.8879	-69.7131	21.5945
17	0.8338	0.3531	-0.7297	1.0271	-0.5876	0.7184	-0.1141	0.119	0.0099	0.4668	0.1396	0.0481	0.1737	-0.1156	0.048	1.2473	-0.4874	0.1807	0.9799	-0.4818	1.1824	-97.9565	-77.0379	73.1084
18	0.0167	-0.0448	-0.0312	0.6002	0.8438	1.1574	0.0614	0.2317	-0.4541	-0.2351	-0.0229	0.0732	0.0189	0.0641	0.0864	0.6226	-0.3424	0.2724	0.9355	-0.352	1.1883	-112.0796	-30.2203	98.0926
19	0.3797	0.2972	-0.1153	0.556	0.1002	0.2172	-0.0035	-0.0199	-0.1868	0.1288	0.2098	-0.255	0.2878	0.2339	-0.1421	0.8072	-0.1087	0.0543	1.0138	-0.4049	1.3104	-49.2525	-89.8881	49.0055
20	0.5893	0.3128	0.2645	1.1875	0.2814	0.6972	-0.189	0.1832	-0.213	0.1036	-0.0613	-0.0864	0.2943	-0.0618	0.0562	1.0962	-0.4578	0.2318	0.9281	-0.5592	1.5147	-82.6784	-94.9444	51.6295
21	4.361	1.5423	1.7175	1.3193	0.665	1.1892	-0.0279	0.2742	0.2135	-0.3727	-0.1104	0.4843	-0.0925	-0.1996	0.0988	0.7316	-0.3447	-0.0239	1.353	-0.444	1.2791	-107.4335	-55.5472	42.9766
22	1.0699	-0.4057	0.2498	0.7367	0.0035	1.4082	0.2456	0.1564	0.3645	0.3109	-0.0919	0.3798	-0.1004	-0.4085	-0.1768	0.6857	-0.0962	0.4101	1.4378	-0.2952	1.3433	-110.8749	12.1323	101.2911
23	0.8718	-0.1589	0.3679	0.3623	0.1854	0.726	0.0874	0.1331	0.4575	0.239	-0.0573	0.2422	-0.0279	-0.276	-0.0523	0.5563	-0.0362	0.3282	1.1469	-0.2012	1.03	-89.954	33.2229	101.6429
24	0.1879	-0.075	0.0447	0.7961	0.393	0.3536	-0.1101	0.1233	-0.0277	-0.1515	-0.0765	0.2073	0.027	0.0506	0.0687	0.5553	-0.0054	0.0901	0.7611	-0.0758	0.6381	-54.4504	21.5375	56.1993
25	1.7162	-0.0653	0.6181	1.1212	-0.0111	0.8746	-0.0836	0.3516	0.1765	-0.4584	0.1462	0.42	-0.1718	-0.432	-0.1277	0.8375	0.3044	-0.1842	1.1764	0.0587	1.052	-73.993	76.9734	33.5425
26	0.3269	-0.5758	0.1211	0.9992	-0.2138	0.0418	-0.0551	-0.249	0.0006	0.0754	-0.1731	0.0341	-0.0888	0.048	0.2024	1.5952	-0.1318	-0.0792	0.9136	-0.1286	1.4731	-63.6372	-101.8275	81.0955
27	1.0851	-0.3145	0.2493	0.4295	0.3192	0.6083	-0.117	-0.3505	-0.3873	0.0711	0.0656	0.47	0.351	-0.261	0.1211	0.9983	-0.4237	0.2523	0.8389	-0.0228	1.3798	-61.1908	-22.81	109.2652
28	1.5741	-0.1818	0.474	0.7406	-0.0134	0.1463	0.1263	-0.5044	0.1189	0.4331	-0.0859	0.1149	-0.1817	-0.2974	-0.0757	1.0224	-0.2107	0.464	1.2446	-0.0959	1.0689	-80.7401	17.2909	141.0075
29	2.2382	-0.2598	0.0035	2.3969	0.0624	2.2664	0.0944	-0.4454	-0.1024	0.6002	-0.0391	-0.2679	-0.2028	0.2769	-0.0229	1.7384	-0.2805	0.0072	1.4408	-0.2125	0.8576	-76.2267	-56.7205	106.9502
30	2.3937	-0.0208	-1.3306	1.0717	0.206	0.9368	0.1145	0.2315	0.1366	0.0394	-0.0688	0.0144	0.0578	-0.1748	-0.0624	0.6119	-0.3516	0.0774	1.2997	-0.4048	1.1458	-79.7754	-47.3354	36.4797
31	1.6946	-1.3597	0.0859	1.1063	-0.058	0.3157	-0.06	-0.0827	-0.4841	-0.0242	0.0515	0.4454	0.0287	-0.4639	-0.0326	0.929	-0.0064	-0.0116	1.2314	-0.2637	0.9609	-80.5014	12.9189	37.5088
32	0.1176	0.0441	-0.329	0.4239	0.5437	1.873	0.0432	0.072	0.0751	-0.1974	0.1433	-0.0099	0.301	-0.0332	-0.0932	1.3427	-0.061	0.1843	1.8367	-0.2633	1.0319	-60.5198	-42.5397	-7.1739
33	1.05	-0.1146	-0.2314	1.1057	0.1625	0.8387	0.0496	-0.2321	0.086	0.1584	0.0309	0.2563	0.1155	-0.1094	-0.066	1.0799	-0.6515	0.4411	1.3992	-0.41	1.3402	-132.4291	-57.6339	86.6029
34	0.185	-0.1345	-0.0657	0.1423	-0.0654	-0.0399	0.16	0.1013	0.2218	0.1105	-0.098	-0.2026	0.0068	-0.0132	-0.0657	0.5874	-0.1007	0.0133	0.9357	-0.1636	0.9773	-54.7635	-40.0374	40.8111
35	0.3165	-0.0548	-0.4665	0.5004	-0.0335	1.0816	0.1035	-0.1206	-0.0253	0.2029	-0.0496	0.0645	0.0163	-0.0816	-0.0524	0.4651	-0.1683	0.0961	0.6438	-0.0563	0.4704	-3.0872	-3.6506	124.1808
36	0.3533	0.0188	0.0417	0.7255	-0.1311	0.5999	0.0547	0.1158	0.2798	0.0867	0.0131	0.0429	-0.342	-0.0712	-0.0819	0.5051	0.0744	0.126	0.5125	0.1865	0.6582	32.1339	61.2548	38.7028
37	0.2159	0.1278	-0.0964	0.2901	0.0755	0.4378	0.0742	-0.0501	-0.1189	0.1056	-0.0949	-0.1893	0.0574	0.1696	0.0257	0.3527	-0.0095	-0.0476	0.5643	0.079	0.562	92.3148	-24.5952	73.4341
38	0.6053	0.0799	0.1265	1.0787	-0.1932	0.561	0.0849	0.2142	-0.3356	-0.1093	0.0696	-0.0589	0.461	-0.0236	-0.1378	0.8728	-0.1515	-0.0389	0.561	-0.2986	0.8773	24.1839	-93.0029	30.2886
39	0.2999	0.1849	-0.1882	0.8907	-0.7569	1.4808	0.0242	-0.0917	-0.1238	-0.1288	-0.2343	-0.2213	-0.0048	0.3618	0.2324	0.3118	-0.0049	0.0906	0.5415	0.0625	0.499	105.7795	12.0864	12.5615
40	0.821	-0.1916	-0.449	1.1611	0.339	1.3329	-0.0363	0.1059	0.0536	-0.1149	0.0547	-0.2509	0.1646	-0.016	0.0035	0.3522	-0.0019	0.0755	0.3927	-0.0681	0.3631	75.6288	-31.2539	16.9417
41	0.4974	-0.4734	-0.3137	1.0001	0.3507	0.1632	-0.1202	-0.2009	-0.1179	0.3373	0.0044	0.1678	-0.0178	-0.0013	0.1048	0.8962	-0.1915	0.1322	0.9889	0.1556	0.4807	28.2182	-39.512	160.9828
42	1.8069	-0.5563	-0.4529	0.6709	0.1142	0.5138	0.0726	0.5436	0.3695	-0.2354	0.0276	0.0967	-0.1878	-0.2913	-0.1148	0.54	0.0897	-0.0326	0.9891	0.2726	0.554	20.5645	33.1835	-8.8019
43	1.1774	-0.2237	0.1074	0.98	-0.2412	0.4827	-0.0487	0.0786	0.0178	-0.214	-0.0116	0.1572	-0.044	-0.1172	0.092	0.4028	-0.1315	-0.0857	0.8515	-0.0025	0.5264	11.3969	-26.9304	12.4019
44	1.1373	-0.1091	-0.0176	0.6983	0.0052	0.7065	-0.0691	0.147	-0.3124	-0.1696	0.071	0.4892	0.3251	-0.6001	0.051	0.7132	-0.2856	-0.079	1.0456	-0.2261	1.1087	-12.6579	-78.5385	29.7957
45	0.3433	0.0771	-0.0013	0.9988	-0.1323	0.8081	-0.0082	-0.2172	-0.1359	0.1492	-0.0442	-0.0959	0.1944	0.1497	0.074	0.4879	-0.0976	-0.0894	0.603	0.1992	0.5083	70.9065	-54.817	111.562
46	0.7199	0.4412	0.2878	0.3937	0.0203	0.5712	0.1428	0.3645	0.1359	-0.0761	-0.0187	-0.0801	0.1049	0.073	-0.0601	0.4876	-0.0946	0.1167	0.7821	0.0973	0.4521	68.5157	14.2761	-15.6582
47	0.3516	-0.1416	-0.1897	0.0295	0.0812	0.5247	0.0152	-0.2034	-0.1303	0.1567	-0.0158	-0.0584	0.1414	-0.052	-0.0158	0.5995	-0.1971	-0.0193	0.6659	0.1723	0.4705	41.9871	-31.9028	127.5077
48	0.7063	-0.159	-0.2588	0.3326	0.2195	0.1765	0.0823	0.3191	0.1263	0.0312	0.0058	0.0365	-0.0511	-0.177	-0.1007	0.3514	0.0637	-0.0171	0.5565	0.1869	0.4427	55.9624	30.1326	12.3331
49	0.2947	-0.0587	0.214	1.1515	0.4052	0.8072	0.154	0.1212	0.2139	-0.14	-0.0141	-0.1925	0.0385	0.1351	-0.1483	0.4911	-0.0798	0.0284	0.3813	0.0075	0.4686	73.0749	40.5055	67.7705
50	0.7293	-0.0986	-0.02	0.4832	0.003	0.4099	0.0565	-0.1035	-0.2762	0.097	-0.0888	-0.129	0.1659	0.1321	0.0708	0.4095	0.0148	0.0371	0.4901	0.1081	0.5849	80.5856	-49.7119	65.5953
51	1.365	-0.3005	0.2837	0.6922	-0.1455	0.7551	0.1297	-0.0675	0.1135	0.1456	0.0011	-0.0699	-0.3409	0.0926	-0.0647	0.761	-0.1783	0.1402	0.5577	-0.2221	0.7497	36.8037	61.9638	111.6813
52	1.2993	0.6912	-0.7472	0.7222	-0.7709	0.8565	0.0523	-0.1009	0.0485	0.0036	-0.0705	0.2148	-0.2506	0.0869	0.0308	0.6299	0.075	0.161	0.7764	-0.1897	0.6303	-15.2684	52.1855	118.4652
53	1.4134	-0.731	-0.3024	0.6135	0.3984	0.371	-0.2	-0.1199	0.0029	0.2588	-0.037	0.3152	0.0073	-0.3683	0.1903	0.8922	0.053	0.1418	1.0732	-0.3873	0.9586	-48.3011	58.482	133.2676
54	0.4565	0.201	-0.38	0.9692	-0.2154	0.5168	0.0241	0.4151	-0.0161	-0.1696	0.0753	0.2717	0.1809	-0.1134	-0.09	0.4802	0.0032	-0.0328	0.8906	-0.0284	0.3604	48.766	-14.105	-4.7479
55	0.1714	0.2562	-0.286	0.3726	-0.4469	0.7804	-0.0773	-0.0408	-0.0669	-0.1087	0.0013	0.0097	0.2191	-0.0911	0.1171	0.5099	-0.0488	-0.0405	0.4582	-0.1809	0.5029	46.0231	-54.8171	29.5079
56	1.3604	0.6044	0.9654	2.143	-0.2684	2.2964	-0.1208	-0.0867	0.2049	-0.0633	-0.1713	0.0334	-0.6886	-0.0616	0.293	1.3902	-0.0244	0.1263	0.696	-0.387	0.9519	23.907	89.8353	118.5943
57	1.1593	0.2353	0.3084	1.5691	-0.2172	0.2542	0.246	0.3011	0.1739	-0.2694	-0.2813	0.2089	-0.0525	0.0229	-0.0136	0.4949	0.1597	0.0878	0.6473	0.0262	0.5488	-7.7725	45.6121	48.2304
58	0.8837	-0.5613	0.3867	0.3848	-0.2437	0.1542	-0.0843	0.2191	0.9297	-0.1559	0.1556	-0.0726	-0.7645	-0.5331	-0.0398	0.9475	0.1911	0.1959	0.688	0.1107	1.2384	-5.1431	81.3998	57.0234
59	0.7023	-0.2492	0.3838	0.4886	0.0884	0.4159	0.0062	-0.2843	0.008	0.2716	-0.0257	-0.0358	-0.0044	0.2041	-0.0117	0.7694	-0.2077	0.0293	0.8317	-0.24	0.4432	52.1363	25.0676	143.2275
60	0.9745	-0.2154	-0.0666	0.934	-0.1698	0.8023	-0.0588	-0.2277	-0.018	0.1086	0.0288	-0.1446	-0.0991	0.1721	0.0204	0.5784	-0.2372	-0.1109	0.9206	0.0281	0.576	100.5671	11.7544	114.0975
61	0.7922	-0.2864	-0.1876	0.668	-0.1342	1.1116	-0.1305	-0.5309	0.0386	0.3429	0.0417	0.1142	-0.1535	-0.031	0.0459	0.9559	-0.02	0.344	1.1396	-0.2573	0.4764	-8.0027	27.6628	173.6197
62	0.2112	0.4013	-0.0629	1.0149	-0.3431	0.4209	0.044	-0.1226	-0.1489	-0.0069	-0.0747	-0.0772	0.1448	0.056	0.0308	0.3948	-0.0188	-0.0237	0.5638	0.0754	0.5495	66.1878	-53.9333	83.8837
63	0.021	0.067	0.1041	2.1765	-0.1749	0.5359	-0.0249	-0.0158	-0.1519	-0.1682	-0.117	-0.2245	0.1664	0.0929	0.164	0.6082	-0.0136	-0.103	0.5935	-0.0978	0.7609	55.8527	-56.1203	51.3175
64	0.539	-0.4446	0.4782	1.3	-0.4156	2.5423	-0.0008	-0.241	0.058	0.0959	-0.0162	0.4662	0.079	-0.4899	0.0385	0.7341	-0.1209	0.34	1.3119	-0.1791	0.7253	-32.703	23.6422	152.4823
65	2.2721	0.3501	0.2823	2.7033	-0.0393	2.1494	-0.0041	-0.0031	0.371	0.0874	0.0974	-0.2646	-0.2586	0.2272	-0.0875	0.5461	-0.0286	0.1389	0.4409	-0.066	0.6728	43.9163	72.123	80.9582
66	2.1052	-0.0475	0.4186	0.4669	-0.1738	0.8996	-0.0114	0.2087	0.0821	-0.021	-0.0755	-0.1218	-0.1855	0.2482	0.0125	0.3441	-0.0619	0.0034	0.4137	0.1352	0.4519	89.5113	-0.0982	57.7887
67	1.7296	0.2557	-0.3358	1.829	0.2872	1.9686	-0.0727	0.1463	0.0343	0.0863	0.1106	-0.2852	-0.0158	-0.0533	-0.107	0.3054	-0.0221	0.0439	0.5667	0.0909	0.4	81.429	14.3223	22.2392
68	1.0668	-0.0543	-0.6768	0.1321	-0.3379	1.2528	-0.1878	-0.3343	-0.0633	0.1487	-0.0581	-0.0601	0.0562	0.009	0.1665	0.8601	-0.1331	0.2315	0.9071	-0.2817	0.5647	5.8454	27.649	144.2439
69	0.3069	-0.2368	0.0212	1.5477	0.1616	0.2443	0.0912	-0.275	0.0518	0.4753	-0.0421	-0.2448	0.0903	-0.026	-0.0569	0.6151	-0.1516	-0.0665	1.0256	-0.0872	0.4511	73.0042	-0.5759	141.7373
70	1.0449	-0.7503	-0.3705	0.7319	0.545	0.9709	0.0386	-0.2276	-0.4668	0.1479	-0.0621	0.1611	0.3126	-0.3395	0.1132	0.8811	-0.3364	-0.0479	0.689	0.2455	0.6964	36.1921	-63.4157	127.38
71	0.6581	-0.5458	0.0821	1.1655	-0.3879	1.0515	0.0079	-0.1231	0.2344	0.2137	-0.0699	-0.0402	0.1796	0.0485	0.0384	0.5128	-0.1351	-0.0203	0.6429	-0.0444	0.4354	53.0196	2.8503	117.7935
72	1.3015	-0.3811	-0.3261	2.6388	0.1823	1.6302	0.0611	-0.1511	0.0334	0.3589	0.0599	0.1364	-0.0594	-0.0631	-0.0724	1.0627	-0.0744	0.0922	1.0277	-0.3953	0.4515	28.5894	61.8532	155.2093
73	2.0244	-0.0097	0.0822	0.7904	-0.0034	0.72	-0.0468	0.3453	0.1225	0.3079	-0.0872	-0.1121	-0.2363	-0.0646	0.0663	0.6568	-0.1309	0.0447	0.701	-0.1103	0.5219	58.9178	24.0125	112.0134
74	0.5783	0.5502	0.5395	1.4525	-0.5574	2.2024	-0.0337	0.2075	-0.0887	-0.2705	0.121	0.185	-0.1304	-0.3245	-0.1641	0.4493	0.0478	-0.0683	1.0713	0.1839	0.5079	7.6193	17.371	2.92
75	1.2281	0.2404	-1.4625	1.1602	-1.2246	2.5367	0.0791	-0.0918	-0.0461	0.1262	-0.0026	0.2209	-0.2419	0.0575	-0.0227	0.5908	-0.0299	0.1108	0.95	0.0071	0.819	-35.4516	5.5357	82.1807
76	0.4097	0.5892	0.2846	2.4173	1.0377	1.7966	0.0892	-0.1641	-0.3117	0.0872	-0.0982	0.2236	0.3285	-0.5191	-0.0258	0.6286	-0.2174	-0.0068	0.5593	0.0599	0.6567	20.0217	-60.7397	77.1314
77	0.5156	-0.1358	0.1422	0.7131	-0.225	1.3474	0.073	-0.3102	0.0418	0.304	0.0558	0.238	-0.2377	-0.1854	-0.103	0.5715	-0.076	0.2939	0.8078	-0.1759	0.622	-17.9266	14.2021	123.4042
78	1.1171	0.1241	-0.3733	0.0169	-0.1479	0.9934	-0.1004	-0.0237	-0.1123	-0.2946	-0.1963	-0.388	0.3806	0.2134	0.2213	0.6173	0.2142	0.4583	0.8166	0.3669	1.5171	294.0951	-1.4843	217.6663
79	1.0432	0.5582	0.1865	1.3944	0.0055	0.5947	0.0205	0.4891	-0.4354	-0.3068	-0.0245	-0.3257	0.1853	0.108	-0.0217	0.8023	0.2072	0.2326	0.8556	-0.2213	0.7465	238.0813	-25.2165	177.0755
80	1.561	-0.317	-0.2006	0.9023	-0.2184	1.3704	-0.1274	-0.0258	0.1043	-0.0333	-0.0051	-0.4031	-0.0042	0.3691	0.164	0.5664	-0.062	-0.1213	0.6411	0.2771	1.1728	276.8267	17.1395	247.1606
81	0.423	0.1329	-0.3114	0.7916	-0.0634	0.9142	0.6532	-0.5091	0.4845	0.7613	-0.2322	-0.0867	-0.738	0.429	-0.4137	1.516	-0.3307	0.2079	0.7402	-0.0808	1.0013	272.7634	-22.624	278.4721
82	0.621	-0.0811	-0.4206	0.752	-0.1613	0.8135	-0.0422	0.0361	0.2338	0.1609	0.0134	-0.4966	-0.1285	0.2845	0.03	0.725	-0.1704	-0.1671	0.5449	0.1414	1.2913	252.3477	87.7519	244.0751
83	1.099	0.5468	0.1455	0.9445	-0.2459	2.4019	-0.0471	0.4131	0.039	-0.456	-0.009	-0.1994	0.6029	-0.2203	0.0085	0.9943	-0.0959	0.1953	0.6412	0.0254	0.7196	254.7649	-69.9558	231.1715
84	1.4562	0.0596	-0.3381	0.9131	0.0602	0.6332	-0.0539	-0.0433	0.3391	0.4293	-0.0688	-0.1148	-0.2253	-0.0289	0.1027	1.0272	0.0468	-0.1421	0.4119	0.0065	0.8206	196.959	103.335	255.6893
85	0.8697	-0.0591	-0.0891	0.6707	0.1056	0.9556	-0.0103	0.2002	0.092	-0.3178	-0.1692	-0.3044	-0.2617	0.1017	0.0917	0.7466	-0.1831	0.215	1.0234	0.4267	1.0746	285.0581	52.7865	186.5191
86	0.589	0.0281	0.0572	1.4932	-0.0905	0.7668	0.0615	0.2922	0.2014	-0.0952	-0.1641	-0.0307	-0.4151	0.0659	0.1355	0.8312	0.0418	0.0123	0.5644	0.2187	0.8254	209.8182	92.1145	210.6569
87	0.8586	0.0608	-0.0644	1.1124	-0.0201	1.2734	0.0179	0.0097	0.3624	0.2974	0.0032	-0.4716	-0.0376	0.3344	-0.1223	0.7133	-0.1039	-0.4192	0.6967	0.1057	1.3498	265.213	50.1406	272.155
88	-0.0025	0.0006	-0.0012	0.2234	-0.1217	0.1186	-0.0169	-0.424	0.1889	0.2821	-0.1716	-0.23	0.0581	0.1143	0.1216	2.1458	-0.4723	0.5571	1.1134	-0.4779	1.4007	256.1164	-26.8514	308.2899
89	1.2727	-1.1492	0.6809	2.401	-0.5846	0.7685	0.0083	0.2689	0.0967	-0.4088	-0.1598	-0.2659	-0.106	0.0893	0.1511	0.77	-0.0491	0.1517	0.5988	0.2178	0.8448	232.8264	71.4237	207.215
90	-0.0017	0.0007	0.0014	0.0261	0.0415	0.0551	0.0399	-0.0317	0.019	0.1033	-0.0572	-0.316	0.0042	0.0301	-0.0236	3.1757	-0.3729	0.8356	2.2064	-0.4042	2.0098	245.3112	-19.5236	339.8985
91	0.383	0.0155	-0.3203	0.8089	-0.1824	0.7002	0.096	0.1726	0.0996	-0.3778	-0.1564	-0.2372	-0.1532	0.3991	0.0138	0.6856	0.0077	0.1731	0.915	0.1253	0.6222	248.2255	33.3558	183.9771
92	0.5062	0.3299	0.3209	1.2847	0.2947	0.6681	0.1649	0.0429	-0.1459	-0.05	-0.1791	0.0686	0.3313	0.1465	-0.0521	0.8008	0.1868	0.0955	0.5746	-0.1378	0.9092	231.5745	-36.89	199.3717
93	1.6252	-0.0586	-0.077	0.6261	0.3442	1.4048	0.3821	0.0134	0.3547	0.3677	0.0599	0.2972	-0.1056	-0.368	-0.1794	0.9448	0.1318	0.612	0.9009	0.3977	1.3406	214.5649	-59.8021	294.5194
94	1.665	-0.1847	-0.6736	1.2822	0.3948	1.2719	-0.1702	-0.0123	0.0571	-0.0236	0.0432	-0.4932	0.386	0.31	0.1649	0.8789	0.1238	0.1303	0.5029	0.1056	0.9956	273.2863	-70.6678	251.6957
95	0.1627	0.3166	-0.1976	1.0207	-0.9925	1.1407	0.3795	0.0235	-0.1925	-0.1978	-0.2424	-0.3287	-0.0198	0.0119	-0.0227	0.7064	0.2116	0.2001	0.7523	0.1808	1.1782	293.257	-25.2387	230.113
96	1.0313	-0.0731	-0.2183	1.3945	-0.0828	0.7727	0.0361	0.3365	0.0608	-0.1898	0.2759	0.3906	0.1527	-0.6464	-0.2843	0.8908	-0.1947	0.0871	0.9893	0.4209	0.8443	220.8237	-81.1086	268.1045
97	1.8979	-0.287	0.1907	1.4911	-0.207	0.9828	-0.179	-0.0716	-0.2684	0.0417	-0.0083	-0.214	0.4934	0.0531	0.1164	1.1195	0.0776	0.0752	0.4997	0.2535	0.9974	254.1111	-87.4908	270.7603
98	0.6782	0.2601	0.5386	0.9876	-0.1945	2.234	0.1561	-0.5097	0.2675	0.9273	-0.0684	-0.5713	-0.3044	0.2962	-0.0746	1.1159	-0.1673	-0.2956	0.9242	0.0811	1.0602	279.553	-49.8162	283.3752
99	1.3478	0.3363	0.2377	0.8539	0.3937	2.711	-0.1041	-0.0622	0.138	-0.1131	-0.2589	-0.5413	0.1692	0.5808	0.2925	0.5027	-0.0015	0.1078	0.8324	0.3611	1.2963	291.5858	18.9483	224.9632
100	0.9137	-0.1996	-0.1227	0.8296	0.0624	1.0871	-0.0426	-0.0696	0.1268	-0.161	-0.1054	-0.5307	-0.1044	0.3699	0.2027	0.462	-0.0687	0.1319	0.5789	0.1568	0.924	270.4293	38.9072	219.2832
101	0.4891	0.1044	-0.0803	0.6755	-0.5539	0.4731	-0.0714	-0.0298	-0.0378	0.1858	-0.0295	-0.1687	0.0103	-0.0746	0.1142	0.5828	-0.0382	-0.0251	0.3992	0.0939	0.6458	226.6969	27.5618	256.9428
102	1.5468	0.1467	0.5935	0.7152	0.1027	0.8157	-0.1399	-0.4654	0.3079	0.382	-0.0725	-0.4993	-0.2779	0.1076	0.1819	1.1835	-0.0596	-0.3754	0.5743	-0.1122	0.9894	239.0078	85.1779	279.7784
103	3.1792	1.8734	0.5689	2.3993	0.4326	2.0088	-0.1143	0.1413	-0.332	-0.2836	0.0886	0.1427	0.2449	-0.1143	0.0456	1.6734	-0.3843	0.3189	0.5712	0.107	0.8979	239.5847	-94.1848	238.9276
104	0.5027	0.3847	0.3581	0.6928	0.113	0.814	-0.0945	0.2786	-0.5885	0.0391	0.128	-0.2931	0.1904	0.163	0.025	0.5421	0.1008	0.2124	0.5927	0.0002	1.0531	245.8641	-18.4942	208.6886
105	1.4514	0.3424	-0.091	1.2569	0.6905	0.7705	-0.0052	0.5261	-0.0319	-0.2899	-0.0109	-0.0875	-0.0806	0.3051	0.0684	0.722	0.037	0.4375	0.9828	0.1041	0.8812	270.1132	21.1586	179.5474
106	1.8736	0.034	0.002	1.9656	0.1332	2.5906	0.1618	0.4923	0.0421	-0.5783	0.0073	0.1787	-0.4344	-0.1779	-0.1739	1.3684	-0.1105	0.3942	1.1364	0.2692	0.9583	257.822	-50.1542	214.6359
107	2.1874	-0.1166	-0.296	1.6171	0.1422	0.3423	0.1235	-0.4181	0.0692	0.5058	-0.1264	0.4446	-0.0607	0.0335	0.0807	1.3601	0.1805	0.3924	0.5807	0.0318	0.9709	250.8749	-39.9923	284.6956
108	2.8372	2.2656	0.5388	2.012	0.8225	0.8561	-0.0647	-0.0194	-0.447	0.5186	0.0115	-0.573	0.0433	0.2362	0.0322	0.9364	-0.0806	-0.2442	0.7106	0.291	1.0367	248.6664	20.8037	281.1664
109	0.0603	0.0239	-0.2616	0.2556	-0.35	1.3866	0.0912	0.0088	0.0707	-0.0542	0.0853	-0.1911	0.1504	0.3048	-0.0489	2.2696	-0.2968	0.3955	1.6282	-0.4693	1.5333	226.8744	-34.4487	322.6905
110	1.023	0.3642	-0.1616	0.9537	0.0234	1.2771	0.1291	0.0629	-0.0374	-0.0383	-0.0745	-0.5526	0.2891	0.6408	-0.0849	0.746	0.3054	0.226	1.1086	0.2133	1.7064	309.731	-52.8337	242.7976
111	0.5373	0.2946	0.1218	0.1047	0.1288	-0.0163	0.1379	-0.2297	-0.1715	-0.0555	0.0714	-0.0872	-0.2333	-0.1324	-0.1563	0.9505	-0.1136	0.1134	0.6228	0.0645	0.9791	216.8931	-39.3683	281.1987
112	0.873	-0.0082	-0.8172	0.4756	0.1507	0.8429	0.0289	0.3291	-0.0707	-0.078	-0.0081	-0.1396	0.0812	-0.0021	-0.0435	0.5599	0.0678	0.0206	0.6741	-0.0853	0.4051	192.09	-6.6916	184.0764
113	0.6672	-0.0231	0.0386	0.3967	0.0665	0.6073	0.0194	0.0101	0.2578	0.0182	0.0445	-0.0158	-0.1918	-0.0471	-0.0787	0.4899	0.0249	0.0485	0.2362	0.0921	0.5425	136.831	66.331	250.2963
114	0.1501	-0.0666	0.1508	0.1093	0.118	0.4772	0.0683	0.1461	-0.0654	-0.0521	0.0346	0.1522	0.1568	-0.2822	-0.0639	0.5793	-0.1262	-0.1804	0.5663	-0.0011	0.5268	88.0935	-26.0442	214.4338
115	0.7029	-0.1151	0.1495	1.4911	-0.5178	0.6612	0.0454	-0.0339	-0.2454	0.0491	0.1913	0.1677	0.23	-0.1457	-0.2405	0.6955	-0.0517	-0.1506	0.3267	0.1162	0.6703	144.8	-84.9988	281.1189
116	0.3653	-0.3789	-0.3902	1.213	0.6945	1.0586	0.1344	-0.0144	-0.2073	0.0552	-0.1604	0.1269	-0.0557	-0.3756	0.0883	0.4063	0.0253	0.1073	0.6259	0.1879	0.6095	60.3166	16.9838	265.5528
117	0.8298	0.006	-0.3866	1.0143	-0.145	0.8916	-0.0148	0.0785	-0.1148	0.1095	0.0567	0.1707	0.1383	-0.0789	-0.0917	0.4294	-0.0689	-0.0188	0.2553	0.1221	0.4225	91.5231	-24.9927	273.6533
118	0.3459	0.1088	-0.002	0.989	-0.0964	0.2096	0.001	0.2315	-0.2183	-0.0127	0.0301	-0.2085	0.1767	0.0956	-0.0009	1.139	0.0929	0.1068	1.0852	-0.393	0.6578	170.4797	-48.3539	146.2752
119	2.7556	0.5889	-0.6953	0.7697	-0.0352	0.378	-0.0814	-0.2324	0.0665	0.1573	0.0732	-0.1123	-0.1128	-0.0089	0.0047	0.5444	0.0077	-0.0072	0.299	-0.0286	0.337	138.1536	44.5168	302.5919
120	0.7308	0.0737	-0.0489	0.9406	0.3972	0.211	-0.2874	-0.142	0.0084	0.5938	-0.0757	-0.4146	-0.3574	0.0124	0.179	1.0788	0.137	-0.4198	0.3719	-0.0491	0.6865	153.7487	-16.4559	291.1468
121	1.6846	0.0424	-0.095	0.6895	0.1878	1.0436	-0.2032	0.0303	-0.0081	0.1701	0.128	-0.2034	0.0337	0.2658	0.0918	0.6984	0.0396	-0.1664	0.3408	-0.0036	0.8078	180.7995	-69.4478	287.5819
122	1.9659	0.8966	-0.03	3.8837	-0.2489	1.2812	-0.0805	-0.1484	-0.3054	0.3166	-0.2352	-0.109	0.3704	0.2361	0.1929	1.1118	-0.228	-0.3188	0.5724	0.1207	1.101	173.2121	21.8815	346.762
123	0.3382	-0.0319	-0.0544	0.628	-0.0267	1.0052	0.0167	0.0353	-0.1795	-0.2469	0.044	0.0945	0.3054	-0.1377	-0.0488	0.8299	-0.0913	-0.1771	0.7187	-0.2411	0.5542	118.279	-59.7497	186.3604
124	0.771	-0.4457	0.3649	0.4914	-0.5718	1.2007	-0.0593	-0.1989	0.1102	-0.0763	0.2387	0.0649	0.0903	-0.2857	-0.1472	0.4391	0.0551	0.1649	0.4708	0.056	0.4609	90.3173	24.699	300.9783
125	0.4254	-0.1706	-0.1353	0.0816	-0.0224	0.1939	0.0847	0.1298	-0.1807	-0.1125	-0.0313	-0.0018	0.1443	0.0078	-0.1141	0.7927	-0.0079	-0.0624	0.6731	-0.2214	0.4928	149.6298	-37.4612	174.5279
126	0.7947	0.1488	0.0605	0.3027	-0.1678	0.3051	-0.0102	-0.1728	0.07	0.0444	0.069	-0.1025	0.046	-0.0134	-0.0573	0.4192	0.0125	0.0318	0.2305	0.0418	0.3339	108.4975	37.5759	274.5652
127	1.4848	-0.0518	0.7139	0.4721	-0.3704	0.7218	0.153	0.1435	0.1488	-0.0533	-0.0681	0.1395	0.1814	-0.1356	-0.0923	0.5269	0.0357	-0.0454	0.4297	0.1679	0.4832	109.9199	41.1188	211.2775
128	0.8814	-0.1251	-0.0173	0.5154	0.0253	0.3508	0.1587	0.1394	-0.2294	-0.1635	-0.0776	0.0782	0.2295	-0.0997	-0.1341	0.5856	-0.1412	-0.0824	0.4446	-0.0614	0.5789	98.0816	-49.4268	227.929
129	1.0527	0.5871	-0.2182	0.7984	0.0527	0.3151	-0.0992	0.172	0.1587	-0.1379	-0.0309	-0.0923	-0.1376	0.0448	0.1426	0.871	-0.0429	-0.0125	0.7321	0.2135	0.5098	148.9515	57.8539	178.6376
130	2.1122	-1.0397	-0.6735	0.7742	0.6656	0.6824	0.4254	0.1968	0.1971	-0.0009	-0.1157	-0.0881	-0.1783	-0.1217	-0.3066	0.674	-0.0541	0.0482	0.5644	0.1433	0.6212	201.0614	50.2693	184.9472
131	3.3266	0.8998	0.5376	0.2335	0.1535	0.0877	-0.2515	0.2933	0.2367	0.001	0.0016	-0.2173	-0.1049	0.4826	0.2135	0.8858	-0.0618	0.072	1.1856	0.3451	0.6576	236.1336	60.5702	178.1847
132	0.7046	-0.0915	-0.2722	1.0188	-0.0121	0.5842	-0.0788	-0.1676	-0.011	0.0986	0.1657	-0.1859	0.0319	-0.0264	-0.0717	0.526	-0.0094	-0.0292	0.3397	0.0657	0.3258	112.4491	-3.9566	298.5271
133	0.2091	-0.2454	-0.2498	0.2817	0.4042	0.489	0.076	0.0941	-0.1222	0.2059	-0.0349	0.0301	0.0871	-0.0271	-0.0297	0.7056	-0.0154	-0.1071	0.3111	0.0766	0.5329	123.6774	-48.1684	271.394
134	1.2391	-0.472	-0.0872	2.0037	-0.268	2.5705	-0.034	0.2027	0.1457	-0.1953	-0.0939	-0.0032	-0.4401	-0.1375	0.0625	1.2509	-0.1098	-0.0392	0.8133	0.4246	0.5221	161.839	85.3919	171.5035
135	1.1087	-0.0702	0.3843	1.4638	-0.0183	0.5599	0.1796	-0.2214	0.1942	0.0887	-0.0958	-0.2897	-0.0382	0.0271	-0.1076	0.5606	-0.0893	-0.0118	0.3188	0.0596	0.5156	178.0721	51.5558	252.2185
136	0.5261	0.9556	0.3803	1.5742	0.6443	0.2793	-0.0727	-0.0007	0.1575	0.0417	0.1338	0.1867	-0.1822	0.0639	-0.0262	0.8013	-0.0491	0.0275	0.4681	0.0884	0.7623	191.1067	100.4983	248.5949
137	0.5573	0.0482	0.0161	0.3678	0.1405	0.4023	0.0759	0.2987	-0.1228	-0.2959	-0.1086	0.1335	-0.0569	-0.1361	-0.0101	0.9358	-0.0878	-0.181	1.0029	0.1608	0.4522	141.9934	16.8362	149.6096
138	1.1546	-0.5038	0.0168	1.5032	-0.1183	0.859	0.0621	0.4476	0.0568	-0.1694	0.0858	0.0089	-0.0064	-0.1425	-0.0719	0.7387	-0.0737	-0.273	1.0431	0.0904	0.5658	88.7194	4.4872	168.6363
139	0.1101	-0.094	-0.0821	0.3148	0.1599	0.9257	0.1423	0.1625	0.0966	-0.2172	0.0005	-0.0609	0.0146	-0.0229	-0.0245	0.9381	-0.1381	0.3906	1.491	-0.0165	0.3576	207.7305	18.3676	133.4189
140	0.2265	-0.1394	-0.0565	0.7479	0.2541	0.1674	-0.0112	0.1358	-0.0645	-0.097	-0.0012	0.0618	0.1449	-0.0713	-0.0479	0.7318	-0.1322	-0.1407	0.5092	-0.0783	0.5349	116.3228	-55.1773	214.0328
141	0.0522	0.2017	-0.0708	4.1318	-0.4763	0.4675	0.0698	0.1218	-0.1681	0.0758	-0.06	0.4963	0.1994	-0.0338	-0.01	0.571	-0.0512	-0.1963	0.4996	0.0547	0.6356	118.8304	-52.6365	248.3492
142	1.2306	0.2059	-0.2037	1.0918	0.8799	2.2342	0.1792	0.1092	0.0067	0.0122	0.0799	-0.36	-0.0855	0.4202	-0.21	0.6277	-0.0101	0.1913	1.2324	-0	0.533	227.2447	18.5581	160.3748
143	2.5431	-1.2771	0.214	3.322	-0.3956	2.4047	-0.0766	0.2652	0.2139	-0.0643	-0.0273	0.1038	-0.222	-0.2298	0.063	0.5151	-0.0717	0.0268	0.531	0.2119	0.5033	134.667	71.515	205.4735
144	1.8632	-0.0207	0.9089	0.4942	0.3466	1.1263	0.1153	-0.0717	0.035	0.1331	-0.0266	0.31	-0.0402	-0.2354	-0.0733	0.358	-0.0591	-0.039	0.5194	0.1111	0.5011	86.737	0.29	227.0428
145	2.0788	-0.3398	-0.7353	1.9086	0.1397	1.8642	-0.091	0.1985	0.0489	-0.0673	0.0686	0.1163	0.0446	-0.3186	0.0731	0.3694	-0.0438	-0.0173	0.4467	0.0672	0.5021	86.1911	19.449	261.3973
146	0.9072	-0.1257	-0.6651	0.1528	0.3565	0.902	-0.0887	0.3107	-0.149	-0.1666	0.0573	0.1633	0.0924	0.0319	-0.0182	0.7359	-0.051	0.0579	0.9938	0.0731	0.3729	187.3569	21.4347	158.6752
147	0.4468	0.1018	0.207	1.1383	-0.2502	0.4669	-0.0447	0.3796	-0.0007	-0.3001	0.1369	0.1325	0.1978	-0.0246	-0.118	0.736	-0.1783	-0.1259	1.1397	0.0297	0.4529	122.2028	-9.6857	149.5617
148	1.2633	0.6849	-0.3599	0.4114	-0.2762	0.8425	0.0023	0.0675	-0.1754	-0.217	0.0645	-0.0268	0.2923	0.3126	0.0107	1.0161	0.1175	-0.0519	0.6065	-0.2705	0.6552	155.9218	-68.3172	180.107
149	0.725	0.5999	0.3012	1.5164	0.4879	1.2197	-0.0773	0.3748	0.0656	-0.1299	-0.0629	-0.0097	-0.0826	-0.2158	0.211	0.6631	-0.047	-0.0007	0.7827	0.0003	0.382	135.9183	-2.355	176.7953
150	1.7027	0.4628	-0.0096	2.8482	0.2473	1.3842	-0.0064	0.1461	0.2848	-0.4285	-0.0529	-0.1783	0.1073	0.1165	0.0383	1.0589	-0.0671	0.1034	1.1323	0.3355	0.5157	166.6526	52.771	138.5683
151	1.4182	-0.1926	0.3684	1.0149	0.0461	1.1619	0.1445	-0.3363	0.0958	-0.2928	-0.0624	0.2446	-0.1557	-0.0516	-0.061	0.7587	0.0116	-0.0924	0.7475	0.0874	0.5688	128.3724	19.0501	178.2103
152	1.1862	0.3112	0.253	3.0963	1.6099	2.8911	-0.244	-0.0874	-0.0651	0.1807	0.0835	-0.0825	-0.0265	0.1038	0.2093	0.4881	-0.036	-0.1392	0.3121	-0.0176	0.4432	153.6627	28.2896	295.9451
153	0.9495	-1.3954	-0.7957	2.2788	1.0756	0.696	-0.1374	0.1914	-0.1333	-0.2945	-0.0476	-0.0143	0.0464	-0.1267	0.1251	0.4765	-0.1494	0.0785	0.4952	-0.0085	0.757	213.9625	9.6366	229.0429
154	0.3762	-0.6273	0.2619	1.8599	-1.3157	2.1596	-0.0509	0.1352	-0.0621	0.0555	-0.0035	-0.3793	0.3358	0.1876	0.0627	0.7081	0.082	-0.0502	0.3827	-0.1268	0.7044	159.529	-59.0117	232.0079
155	1.0142	-0.5	-0.7946	0.5307	0.4798	1.409	0.1075	0.1779	0.2111	-0.3937	0.0883	-0.2191	-0.165	0.1053	-0.1739	0.5161	0.0024	0.1221	0.7468	0.0282	0.3993	205.8367	12.036	185.8731
156	2.1941	0.3109	-0.4874	0.5834	-0.8069	1.3658	-0.0484	-0.4789	0.2051	0.2574	-0.1929	-0.0308	-0.054	-0.0602	0.2335	1.4131	-0.2217	-0.0298	0.8721	-0.0521	0.7937	134.2113	15.3201	349.8049
157	2.3955	1.0451	0.8622	1.2177	0.5272	0.354	-0.0906	0.5603	0.0158	-0.423	0.0364	-0.4493	0.0688	0.525	0.0225	2.0126	-0.1819	0.3957	2.1302	-0.0489	2.0529	117.4262	15.7032	368.8568
158	0.0143	-0.0013	-0.0236	0.2878	-0.4217	0.6612	0.1222	0.3462	0.1686	-0.2639	0.0639	0.1285	-0.1851	-0.2638	-0.158	2.5696	0.1061	0.3931	2.5264	-0.0724	2.316	102.6673	12.7816	377.5401
159	0.2437	0.0162	-0.0639	0.151	-0.0227	0.1904	0.0532	-0.0336	0.04	0.0599	-0.0492	-0.0044	-0.0282	-0.0219	-0.0109	0.3686	-0.0696	-0.0063	0.4249	-0.016	0.4147	39.2834	2.1417	75.7913
160	2.8203	0.7197	-0.6465	0.183	-0.159	0.1484	0.0011	-0.1236	-0.4819	0.1356	0.2963	1.0999	0.3003	-0.8544	-0.2018	1.0472	-0.3915	-0.021	1.7973	-0.0327	1.5307	-17.0974	-48.5211	14.9749
161	0.2293	0.062	0.3344	0.5723	0.0298	0.4934	-0.2856	0.1774	-0.0899	-0.1793	0.1619	1.341	0.0578	-0.805	0.1168	1.4383	0.0827	-0.196	2.0762	-0.0134	1.6883	-2.2013	-0.0646	-24.7792
162	1.0583	-0.5494	-0.9103	1.1148	0.3088	0.9251	-0.1179	-1.1727	0.6464	0.8739	-0.4453	-0.2194	-0.4958	-0.4615	0.5508	1.4697	0.0084	0.0602	1.423	-0.1593	1.0877	28.0568	0.9465	155.84
163	0.7808	0.2554	-0.3525	1.3435	-0.2494	0.9574	0.225	0.0922	-0.0308	-0.0493	-0.0279	0.203	0.1946	0.029	-0.1859	0.7546	-0.0564	0.1543	0.9188	-0.3021	0.8007	-29.7784	-15.525	61.567
164	0.1772	0.179	0.2614	0.1912	0.277	0.4012	0.0233	-0.3788	-0.8427	0.0879	0.1307	0.6904	0.9485	-0.7251	-0.134	2.1828	-0.403	0.024	2.542	-0.5456	2.2805	-21.776	-27.3367	163.3808
165	2.0201	-0.9105	-1.8598	4.1672	-0.9842	2.6583	0.1792	-0.8001	0.439	0.9276	-0.0283	-0.9122	-0.4278	0.4411	-0.1662	1.5844	-0.1935	-0.0592	1.8965	-0.1257	1.0695	11.6394	-2.2657	182.1642
166	0.0642	0.286	0.2308	1.4761	1.231	1.0419	0.0904	-0.9646	1.1045	0.7974	0.4508	-0.0012	-1.0189	-0.1086	-0.5255	1.4534	0.1178	0.1993	1.2297	-0.445	1.6047	-4.8417	88.9003	100.8416
167	0.5304	0.406	0.196	0.896	-0.0239	0.2439	0.0064	0.3018	-0.2774	-0.3168	0.0307	0.0224	0.2662	-0.0379	-0.0409	0.7271	-0.1514	-0.0402	0.7922	-0.2723	0.6375	23.7402	-66.7313	16.8188
168	0.2413	0.022	-0.1782	0.1614	-0.0968	0.5466	0.0703	-0.2828	0.074	0.2519	-0.0457	-0.09	-0.1241	0.1238	0.0123	0.5724	-0.1536	-0.0404	0.7684	-0.0787	0.4331	63.1651	7.7664	126.4118
169	0.2947	0.0039	-0.1027	0.4876	-0.101	0.2337	0.0301	0.1235	0.147	-0.12	-0.042	0.2362	-0.1681	-0.2434	0.0296	0.5982	0.1922	-0.0074	0.8404	-0.0521	0.74	-54.3435	63.4977	62.8422
170	3.3227	2.5537	-1.6656	7.2161	3.306	6.0106	-0.2332	0.7174	0.8194	-1.0551	-0.1344	1.4241	-1.1026	-1.0962	0.2893	1.2198	0.449	-0.2487	1.4477	0.1239	1.2191	-49.4998	102.2202	34.4831
171	2.1467	-0.4	0.2644	5.3843	1.9784	0.8073	0.0593	-0.3701	0.5352	0.4164	0.0656	0.374	-0.7257	-0.4904	-0.094	1.8334	0.3779	-0.0857	1.5958	-0.2488	2.0216	-42.7955	127.7631	104.2604
172	3.1533	0.6387	-0.4009	0.2837	-0.5334	1.4113	0.1342	0.0278	0.7898	0.3347	0.067	0.0572	-0.6062	-0.2511	-0.1086	1.8684	-0.1478	0.2874	1.7628	-0.5117	1.9853	-59.3199	113.3327	118.3576
173	0.0209	0.1762	0.0175	1.4865	0.1453	0.025	-0.3211	-0.2749	-0.2792	0.2968	-0.1536	0.5506	0.3856	-0.2127	0.3522	2.3324	-0.0845	-0.3421	2.4387	-0.1914	2.2672	-112.3507	14.8887	27.5622
174	0.5272	0.1476	-0.0206	1.485	-0.304	0.3315	-0.0187	0.4237	-0.1065	-0.4387	0.019	0.3561	-0.0314	-0.6048	-0.1232	0.9795	0.2128	-0.1633	1.7371	0.0077	1.104	-83.823	48.8452	24.6353
175	0.5515	0.0388	-0.077	0.7279	-0.061	0.3478	0.0738	-0.1377	-0.1176	0.3184	-0.1401	0.2218	0.0515	-0.2281	0.0472	0.5997	-0.1662	0.1413	0.8295	-0.1924	0.7408	-60.6498	10.4868	106.1813
176	0.4757	0.4023	-0.5837	1.0018	0.6467	2.6524	0.1055	0.183	0.5131	-0.2569	0.3573	0.5353	-0.9813	-1.2596	-0.3739	1.3724	0.3778	0.1481	1.7326	-0.3544	2.2732	-109.1763	58.0873	96.7541
177	0.0151	-0.0057	0.069	0.2221	-0.0805	0.3127	-0.3017	-0.0568	0.0058	-0.315	0.1101	0.7245	0.1014	-0.7247	0.2125	2.2438	0.2269	0.1302	2.3545	-0.1256	1.9441	-99.9084	79.4223	108.953
178	0.0749	-0.0607	-0.3248	0.3915	-0.1552	1.634	-0.0228	0.1966	0.1709	-0.0445	-0.0192	0.2597	-0.2355	0.2623	0.0421	0.6962	0.1782	0.1074	1.1874	-0.2179	1.2382	-80.2538	56.5947	78.7735
179	0.2508	0.9827	-0.3054	3.6265	-1.1422	0.3577	0.2823	0.0941	0.2762	0.256	-0.3368	0.4266	-0.5521	-0.2079	-0.0033	1.3253	-0.0231	0.2743	1.4624	-0.5421	1.5008	-63.9178	78.7311	127.065
180	0.1537	0.1468	0.0012	0.2577	0.192	0.238	-0.0079	0.2118	-0.1221	0.0698	-0.0587	0.0759	0.1603	-0.2083	0.0402	0.6742	-0.2587	0.0583	1.1159	-0.3645	1.0467	-74.657	-47.6507	56.1748
181	0.4462	0.3325	-0.0761	0.9057	-0.0042	0.1357	0.0845	0.1185	-0.05	-0.0284	-0.1405	0.0265	-0.0614	-0.1462	0.0682	0.5208	0.083	0.0097	0.7271	-0.1136	0.6506	-35.7899	24.7265	74.4963
182	0.1979	0.0131	-0.0043	0.15	-0.0218	0.155	0.0131	0.1521	-0.0092	-0.0727	0.0247	0.0333	0.0431	-0.0357	-0.0433	0.4878	-0.0102	-0.0635	0.3985	0.0184	0.3789	139.3852	2.839	220.7223
183	4.1849	-0.7064	0.4936	0.1465	-0.0428	0.2136	0.0145	-0.3885	-0.9621	0.4185	0.4479	-1.66	0.5459	1.5592	-0.3503	1.3572	0.2422	-0.3352	1.5901	-0.125	1.8534	182.6819	-36.719	298.5394
184	0.7868	0.1796	0.7072	0.7625	0.2014	0.67	0.2868	0.1717	0.0742	0.1983	-0.3181	-0.2559	0.0773	0.052	0.0723	1.26	-0.1759	0.0458	0.8152	0.1053	0.7554	154.3307	21.6541	329.6538
185	1.3945	0.1764	-0.4332	0.8029	0.1203	0.1743	-0.1623	1.4116	0.6151	-0.9867	0.131	-0.0656	-0.439	0.7962	0.0811	1.7604	-0.2921	0.0583	1.9695	0.0698	1.1073	169.6468	-7.7874	145.8341
186	1.068	-0.4789	-0.8825	1.8622	0.0863	1.0228	0.1346	-0.2372	-0.1948	0.2348	-0.0936	-0.2068	0.3567	-0.2458	-0.0623	0.7969	-0.0646	0.047	0.7967	0.1089	0.8091	205.0533	-10.9331	248.9619
187	0.6655	0.0028	-0.5802	0.0285	-0.0525	0.5831	0.0463	-0.0371	-1.2344	-0.0804	0.0653	-0.5798	1.1824	0.7458	-0.0457	2.4202	0.3287	-0.1213	2.2325	-0.1718	2.093	220.1345	-35.4974	151.5855
188	5.2391	-0.3771	-1.0484	4.5207	1.3555	0.9657	0.1721	0.9656	0.2796	-1.0464	-0.1054	0.595	-0.2884	-0.1189	-0.0822	1.7739	-0.0539	0.1027	1.6923	-0.337	1.1394	191.5823	-13.7508	124.5208
189	0.0004	-0.0053	0.0034	0.0092	-0.0058	0.0001	0.1711	0.6828	0.8093	-0.4535	0.2316	-0.0436	-0.7489	0.258	-0.2852	1.4114	-0.1287	0.1541	1.049	0.5798	1.2683	186.7175	88.1713	196.1005
190	0.5316	-0.4551	0.3371	0.6297	-0.4055	0.1627	-0.0852	-0.1722	-0.1998	0.5333	0.1999	0.1467	-0.0082	-0.1288	-0.1003	0.7492	0.0678	-0.031	0.366	0.0584	0.4668	142.4531	-57.0066	290.5862
191	0.2556	-0.0673	-0.1285	0.1238	0.1682	0.5885	0.0428	0.3514	0.0617	-0.2054	0.0602	0.048	-0.0069	-0.0931	-0.0254	0.7869	-0.0793	-0.1129	0.9078	0.0345	0.4614	127.9712	0.8703	165.5948
192	0.3484	-0.0967	0.0178	0.6296	0.0287	0.2333	-0.0281	0.0159	0.2119	0.1208	-0.0708	-0.3011	-0.1638	0.0719	0.1007	0.616	-0.1058	-0.0905	0.4308	0.0962	0.7201	226.5993	68.8988	248.1255
193	3.194	-1.5404	-2.5476	4.8923	-1.7563	4.171	0.1081	-0.7737	0.9526	0.8368	-0.2962	-0.5274	-0.5902	0.8182	0.1372	1.3844	-0.1788	-0.4097	0.5855	-0.1947	1.1208	214.2293	109.2584	272.5669
194	1.9767	0.5072	-0.2873	2.7506	0.0335	0.0468	0.3012	0.6112	0.9301	-0.2543	0.1893	-0.2544	-0.8249	0.2246	-0.4079	2.1208	-0.2745	-0.0936	1.1697	0.3252	1.9149	221.4887	131.3931	201.665
195	0.1335	0.1786	0.1243	0.2413	0.179	0.1349	-0.0677	-0.11	0.6486	-0.2768	-0.0764	-0.0933	-0.6193	-0.0632	0.0326	2.6884	0.2055	0.1797	2.5776	0.2397	2.5845	241.4981	117.8051	191.4646
196	0.6554	-1.0878	0.3103	3.2396	-0.303	1.3981	-0.2904	0.1761	-0.1639	-0.2806	-0.3283	-0.6076	0.5207	0.6193	0.4623	2.1898	0.1562	-0.7361	1.8164	-0.1087	1.6579	277.726	25.3994	297.1744
197	0.4686	-0.0926	0.0635	0.8189	0.4015	0.2262	-0.1106	-0.3003	0.2879	0.1546	0.0788	0.0174	-0.1499	0.1999	0.0563	1.1187	-0.1604	-0.4052	0.9265	0.0012	1.0459	247.6232	57.868	292.2301
198	0.4433	0.0556	0.0934	0.7873	0.2206	0.294	0.0382	0.2092	-0.0148	-0.1389	-0.0815	-0.2673	0.0016	0.1356	0.0547	0.4799	0.0311	0.125	0.5814	0.138	0.6917	243.6018	14.753	209.9235
199	1.0779	0.0477	1.1528	0.7025	-0.3813	3.7092	0.1274	-0.5574	0.0946	0.6349	0.2241	-0.3907	-0.4565	0.9874	-0.237	1.6496	-0.3233	-0.0246	2.0108	0.2145	2.1692	290.6505	59.4292	235.9978
200	1.9151	1.4401	-0.8064	2.8175	-1.9238	1.336	0.041	0.6313	0.1094	-0.5425	0.3092	-0.0719	-0.0846	0.1474	-0.2022	2.3667	-0.363	-0.0359	2.043	0.1568	1.9488	272.184	89.3494	187.0343
201	0.4516	-0.1932	-0.6769	0.4059	0.3177	1.0424	0.0473	0.0944	0.0237	-0.0097	-0.1572	-0.194	-0.3628	-0.1067	0.0411	0.6673	-0.1738	0.0225	0.5954	0.2432	1.1135	255.3861	62.8948	238.4831
202	1.1154	-0.7405	-0.3839	0.9178	0.6157	0.7385	0.1027	0.0056	0.292	0.0682	0.0471	-0.0111	-0.4136	-0.0944	-0.0722	1.4366	-0.1171	0.0571	1.3288	0.5275	1.2137	249.1313	83.226	187.4292
203	-0.2657	-0.0117	0.1527	1.1458	-0.3918	0.3076	-0.0142	-0.0123	-0.011	0.4101	0.1231	0.0802	0.0148	-0.0488	-0.0275	0.7561	0.101	0.2028	0.5982	0.2554	0.8926	248.589	-40.5071	264.3223
204	0.5341	-0.0172	-0.0716	0.4567	0.1156	0.398	0.052	0.0197	0.1358	-0.0598	-0.0811	-0.0097	-0.1958	-0.0038	0.0515	0.5591	-0.0849	-0.0234	0.534	0.095	0.5156	208.3599	47.9922	235.0118

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details	Auth seq-ID	Auth asym-ID
1	X-RAY DIFFRACTION	1	segid S0A	0
2	X-RAY DIFFRACTION	2	segid S1A	0
3	X-RAY DIFFRACTION	3	segid S2A	0
4	X-RAY DIFFRACTION	4	segid S3A	0
5	X-RAY DIFFRACTION	5	segid S4A	0
6	X-RAY DIFFRACTION	6	segid S5A	0
7	X-RAY DIFFRACTION	7	segid S6A	0
8	X-RAY DIFFRACTION	8	segid S7A	0
9	X-RAY DIFFRACTION	9	segid S8A	0
10	X-RAY DIFFRACTION	10	segid S9A	0
11	X-RAY DIFFRACTION	11	segid S10A	1 - 96	0
12	X-RAY DIFFRACTION	12	segid S11A	2 - 156	1
13	X-RAY DIFFRACTION	13	segid S12A	20 - 143	2
14	X-RAY DIFFRACTION	14	segid S13A	2 - 151	3
15	X-RAY DIFFRACTION	15	segid S14A	11 - 137	4
16	X-RAY DIFFRACTION	16	segid S15A	8 - 131	5
17	X-RAY DIFFRACTION	17	segid S16A	3 - 143	6
18	X-RAY DIFFRACTION	18	segid S17A	2 - 126	7
19	X-RAY DIFFRACTION	19	segid S18A	2 - 146	8
20	X-RAY DIFFRACTION	20	segid S19A	2 - 144	9
21	X-RAY DIFFRACTION	21	segid S20A	15 - 121	0
22	X-RAY DIFFRACTION	22	segid S21A	1 - 87	1
23	X-RAY DIFFRACTION	23	segid S22A	2 - 130	2
24	X-RAY DIFFRACTION	24	segid S23A	2 - 145	3
25	X-RAY DIFFRACTION	25	segid S24A	2 - 135	4
26	X-RAY DIFFRACTION	26	segid S25A	36 - 105	5
27	X-RAY DIFFRACTION	27	segid S26A	2 - 500	6
28	X-RAY DIFFRACTION	28	segid S27A	2 - 101	7
29	X-RAY DIFFRACTION	29	segid S28A	5 - 67	8
30	X-RAY DIFFRACTION	30	segid S29A	4 - 99	9
31	X-RAY DIFFRACTION	31	segid S30A	2 - 61	0
32	X-RAY DIFFRACTION	32	segid S31A	82 - 501	1
33	X-RAY DIFFRACTION	33	segid SRKA	2 - 319	R
34	X-RAY DIFFRACTION	34	segid STMA	9 - 176	M
35	X-RAY DIFFRACTION	35	segid L2A	0
36	X-RAY DIFFRACTION	36	segid L3A	0
37	X-RAY DIFFRACTION	37	segid L4A	0
38	X-RAY DIFFRACTION	38	segid L5A	0
39	X-RAY DIFFRACTION	39	segid L6A	0
40	X-RAY DIFFRACTION	40	segid L7A	0
41	X-RAY DIFFRACTION	41	segid L8A	0
42	X-RAY DIFFRACTION	42	segid L9A	0
43	X-RAY DIFFRACTION	43	segid L10A	2 - 221	0
44	X-RAY DIFFRACTION	44	segid L11A	6 - 174	1
45	X-RAY DIFFRACTION	45	segid L13A	2 - 194	3
46	X-RAY DIFFRACTION	46	segid L14A	3 - 138	4
47	X-RAY DIFFRACTION	47	segid L15A	2 - 204	5
48	X-RAY DIFFRACTION	48	segid L16A	3 - 199	6
49	X-RAY DIFFRACTION	49	segid L17A	2 - 184	7
50	X-RAY DIFFRACTION	50	segid L18A	2 - 186	8
51	X-RAY DIFFRACTION	51	segid L19A and resid 2:73	2 - 73	9
52	X-RAY DIFFRACTION	52	segid L19A and resid 74:126	74 - 126	9
53	X-RAY DIFFRACTION	53	segid L19A and resid 127:183	127 - 183	9
54	X-RAY DIFFRACTION	54	segid L20A	1 - 172	0
55	X-RAY DIFFRACTION	55	segid L21A	2 - 160	1
56	X-RAY DIFFRACTION	56	segid L22A	9 - 108	2
57	X-RAY DIFFRACTION	57	segid L23A	2 - 137	3
58	X-RAY DIFFRACTION	58	segid L24A	1 - 98	4
59	X-RAY DIFFRACTION	59	segid L25A	22 - 142	5
60	X-RAY DIFFRACTION	60	segid L26A	2 - 127	6
61	X-RAY DIFFRACTION	61	segid L27A	2 - 136	7
62	X-RAY DIFFRACTION	62	segid L28A	2 - 149	8
63	X-RAY DIFFRACTION	63	segid L29A	2 - 59	9
64	X-RAY DIFFRACTION	64	segid L30A	9 - 105	0
65	X-RAY DIFFRACTION	65	segid L31A	4 - 112	1
66	X-RAY DIFFRACTION	66	segid L32A	2 - 128	2
67	X-RAY DIFFRACTION	67	segid L33A	2 - 107	3
68	X-RAY DIFFRACTION	68	segid L34A	2 - 113	4
69	X-RAY DIFFRACTION	69	segid L35A	2 - 120	5
70	X-RAY DIFFRACTION	70	segid L36A	2 - 100	6
71	X-RAY DIFFRACTION	71	segid L37A	2 - 100	7
72	X-RAY DIFFRACTION	72	segid L38A	2 - 78	8
73	X-RAY DIFFRACTION	73	segid L39A	2 - 51	9
74	X-RAY DIFFRACTION	74	segid L40A	77 - 500	0
75	X-RAY DIFFRACTION	75	segid L41A	1 - 25	1
76	X-RAY DIFFRACTION	76	segid L42A	2 - 501	2
77	X-RAY DIFFRACTION	77	segid L43A	2 - 501	3
78	X-RAY DIFFRACTION	78	segid S0B	0
79	X-RAY DIFFRACTION	79	segid S1B	0
80	X-RAY DIFFRACTION	80	segid S2B	0
81	X-RAY DIFFRACTION	81	segid S3B	0
82	X-RAY DIFFRACTION	82	segid S4B	0
83	X-RAY DIFFRACTION	83	segid S5B	0
84	X-RAY DIFFRACTION	84	segid S6B	0
85	X-RAY DIFFRACTION	85	segid S7B	0
86	X-RAY DIFFRACTION	86	segid S8B	0
87	X-RAY DIFFRACTION	87	segid S9B	0
88	X-RAY DIFFRACTION	88	segid S10B	1 - 98	0
89	X-RAY DIFFRACTION	89	segid S11B	2 - 147	1
90	X-RAY DIFFRACTION	90	segid S12B	20 - 143	2
91	X-RAY DIFFRACTION	91	segid S13B	2 - 151	3
92	X-RAY DIFFRACTION	92	segid S14B	10 - 137	4
93	X-RAY DIFFRACTION	93	segid S15B	4 - 138	5
94	X-RAY DIFFRACTION	94	segid S16B	2 - 143	6
95	X-RAY DIFFRACTION	95	segid S17B	2 - 122	7
96	X-RAY DIFFRACTION	96	segid S18B	2 - 146	8
97	X-RAY DIFFRACTION	97	segid S19B	2 - 144	9
98	X-RAY DIFFRACTION	98	segid S20B	12 - 121	0
99	X-RAY DIFFRACTION	99	segid S21B	1 - 87	1
100	X-RAY DIFFRACTION	100	segid S22B	2 - 130	2
101	X-RAY DIFFRACTION	101	segid S23B	2 - 145	3
102	X-RAY DIFFRACTION	102	segid S24B	2 - 135	4
103	X-RAY DIFFRACTION	103	segid S25B	37 - 105	5
104	X-RAY DIFFRACTION	104	segid S26B	2 - 500	6
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