登録情報 | データベース: PDB / ID: 2y8i |
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タイトル | Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 |
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要素 | MYOSIN-2 HEAVY CHAIN |
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キーワード | MOTOR PROTEIN / ADP COMPLEX |
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機能・相同性 | 機能・相同性情報
calcium-dependent ATPase activity / pseudopodium retraction / uropod retraction / cytoplasmic actin-based contraction involved in forward cell motility / phagocytic cup base / pathogen-containing vacuole / response to differentiation-inducing factor 1 / equatorial cell cortex / contractile actin filament bundle assembly / cell trailing edge ...calcium-dependent ATPase activity / pseudopodium retraction / uropod retraction / cytoplasmic actin-based contraction involved in forward cell motility / phagocytic cup base / pathogen-containing vacuole / response to differentiation-inducing factor 1 / equatorial cell cortex / contractile actin filament bundle assembly / cell trailing edge / contractile vacuole organization / myosin filament assembly / aggregation involved in sorocarp development / culmination involved in sorocarp development / RHO GTPases activate PAKs / adenyl nucleotide binding / actomyosin contractile ring / hypotonic response / uropod / actin-myosin filament sliding / detection of mechanical stimulus / apical cortex / negative regulation of actin filament polymerization / bleb assembly / actomyosin / substrate-dependent cell migration, cell extension / myosin filament / filopodium assembly / early phagosome / myosin II complex / cortical actin cytoskeleton organization / microfilament motor activity / cortical actin cytoskeleton / pseudopodium / cytoskeletal motor activity / cleavage furrow / mitotic cytokinesis / response to mechanical stimulus / 14-3-3 protein binding / response to cAMP / extracellular matrix / cell motility / response to hydrogen peroxide / chemotaxis / actin filament binding / protein localization / regulation of cell shape / cell cortex / cytoplasmic vesicle / cytoskeleton / calmodulin binding / ATP binding / identical protein binding / cytosol類似検索 - 分子機能 Myosin tail / Myosin tail / Myosin N-terminal SH3-like domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) / Myosin motor domain profile. / Myosin. Large ATPases. ...Myosin tail / Myosin tail / Myosin N-terminal SH3-like domain / Myosin S1 fragment, N-terminal / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Myosin head, motor domain / Myosin head (motor domain) / Myosin motor domain profile. / Myosin. Large ATPases. / IQ motif profile. / Kinesin motor domain superfamily / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / Myosin-2 heavy chain類似検索 - 構成要素 |
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生物種 | ![](img/tx_eukaryote.gif) DICTYOSTELIUM DISCOIDEUM (キイロタマホコリカビ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.132 Å |
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データ登録者 | Preller, M. / Bauer, S. / Adamek, N. / Fujita-Becker, S. / Fedorov, R. / Geeves, M.A. / Manstein, D.J. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2011 タイトル: Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. 著者: Preller, M. / Bauer, S. / Adamek, N. / Fujita-Becker, S. / Fedorov, R. / Geeves, M.A. / Manstein, D.J. |
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履歴 | 登録 | 2011年2月7日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2011年7月20日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年10月12日 | Group: Database references |
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改定 1.2 | 2018年6月20日 | Group: Advisory / Data collection / カテゴリ: pdbx_unobs_or_zero_occ_residues |
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改定 1.3 | 2019年7月31日 | Group: Advisory / Data collection / Derived calculations カテゴリ: pdbx_struct_conn_angle / pdbx_validate_close_contact ...pdbx_struct_conn_angle / pdbx_validate_close_contact / struct_conn / struct_conn_type Item: _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id ..._pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value |
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改定 1.4 | 2023年12月20日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_residues / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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