Entry Database : PDB / ID : 2x6o Structure visualization Downloads & linksTitle Tet Repressor class D in complex with 7-chlor-2-cyano-iso- tetracycline ComponentsTETRACYCLINE REPRESSOR PROTEIN CLASS D Details Keywords TRANSCRIPTION / TRANSCRIPTION REGULATION / ANTIBIOTIC RESISTANCEFunction / homology Function and homology informationFunction Domain/homology Component
transcription cis-regulatory region binding / DNA-binding transcription factor activity / response to antibiotic / negative regulation of DNA-templated transcription / metal ion binding Similarity search - Function Tetracycline transcriptional regulator, TetR / Tetracycline repressor TetR, C-terminal / Tetracyclin repressor-like, C-terminal domain / DNA-binding HTH domain, TetR-type, conserved site / TetR-type HTH domain signature. / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type ... Tetracycline transcriptional regulator, TetR / Tetracycline repressor TetR, C-terminal / Tetracyclin repressor-like, C-terminal domain / DNA-binding HTH domain, TetR-type, conserved site / TetR-type HTH domain signature. / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type / TetR-type HTH domain profile. / Homeodomain-like / Homeobox-like domain superfamily / Arc Repressor Mutant, subunit A / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species ESCHERICHIA COLI (E. coli)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.3 Å DetailsAuthors Volkers, G. / Hinrichs, W. CitationJournal : J.Med.Chem. / Year : 2011Title : Recognition of Drug Degradation Products by Target Proteins: Isotetracycline Binding to Tet Repressor.Authors : Volkers, G. / Petruschka, L. / Hinrichs, W. History Deposition Feb 18, 2010 Deposition site : PDBE / Processing site : PDBERevision 1.0 Mar 2, 2011 Provider : repository / Type : Initial releaseRevision 1.1 Feb 1, 2012 Group : Database references / Version format complianceRevision 1.2 Jul 24, 2019 Group : Data collection / Category : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_siteRevision 1.3 Mar 18, 2020 Group : Derived calculations / OtherCategory : pdbx_database_status / pdbx_struct_assembly ... pdbx_database_status / pdbx_struct_assembly / pdbx_struct_assembly_gen / pdbx_struct_assembly_prop / pdbx_struct_oper_list Item : _pdbx_database_status.status_code_sf / _pdbx_struct_assembly.oligomeric_count ... _pdbx_database_status.status_code_sf / _pdbx_struct_assembly.oligomeric_count / _pdbx_struct_assembly.oligomeric_details / _pdbx_struct_assembly_gen.oper_expression Revision 1.4 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Show all Show less