Entry Database : PDB / ID : 2w9d Structure visualization Downloads & linksTitle Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution. ComponentsICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN DetailsKeywords IMMUNE SYSTEM / PRION / PRP / FABFunction / homology Immunoglobulins / Immunoglobulin-like / Sandwich / Mainly Beta Function and homology informationBiological species MUS MUSCULUS (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.57 Å DetailsAuthors Antonyuk, S.V. / Trevitt, C.R. / Strange, R.W. / Jackson, G.S. / Sangar, D. / Batchelor, M. / Jones, S. / Georgiou, T. / Cooper, S. / Fraser, C. ...Antonyuk, S.V. / Trevitt, C.R. / Strange, R.W. / Jackson, G.S. / Sangar, D. / Batchelor, M. / Jones, S. / Georgiou, T. / Cooper, S. / Fraser, C. / Khalili-Shirazi, A. / Clarke, A.R. / Hasnain, S.S. / Collinge, J. CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2009Title : Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.Authors: Antonyuk, S.V. / Trevitt, C.R. / Strange, R.W. / Jackson, G.S. / Sangar, D. / Batchelor, M. / Cooper, S. / Fraser, C. / Jones, S. / Georgiou, T. / Khalili-Shirazi, A. / Clarke, A.R. / ... Authors : Antonyuk, S.V. / Trevitt, C.R. / Strange, R.W. / Jackson, G.S. / Sangar, D. / Batchelor, M. / Cooper, S. / Fraser, C. / Jones, S. / Georgiou, T. / Khalili-Shirazi, A. / Clarke, A.R. / Hasnain, S.S. / Collinge, J. History Deposition Jan 23, 2009 Deposition site : PDBE / Processing site : PDBERevision 1.0 Feb 3, 2009 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Advisory / Refinement description / Version format complianceRevision 2.0 Mar 11, 2020 Group : Advisory / Derived calculations ... Advisory / Derived calculations / Other / Polymer sequence Category : entity_poly / pdbx_database_status ... entity_poly / pdbx_database_status / pdbx_unobs_or_zero_occ_atoms / struct_conn Item : _entity_poly.pdbx_seq_one_letter_code_can / _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flagRevision 2.1 Dec 13, 2023 Group : Advisory / Data collection ... Advisory / Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_atoms / struct_conn / struct_conn_type / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Show all Show less Remark 700 SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.