C: Cetuximab mutant light chain,Uncharacterized protein D: Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain A: Cetuximab mutant light chain,Uncharacterized protein B: Cetuximab mutant Fab heavy chain,Immunoglobulin gamma-1 heavy chain hetero molecules
Mass: 23504.904 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Production host: Homo sapiens (human) / References: UniProt: Q8TCD0
Mass: 23829.629 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Production host: Homo sapiens (human) / References: UniProt: P0DOX5
Resolution: 1.7→47.42 Å / Cor.coef. Fo:Fc: 0.969 / Cor.coef. Fo:Fc free: 0.959 / SU B: 3.974 / SU ML: 0.065 / Cross valid method: THROUGHOUT / ESU R: 0.088 / ESU R Free: 0.087 / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
Num. reflection
% reflection
Selection details
Rfree
0.19707
6362
5.1 %
RANDOM
Rwork
0.17157
-
-
-
obs
0.17284
118489
99.92 %
-
Solvent computation
Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å