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Showing 1 - 50 of 79 items for (author: xu & jf)

EMDB-53976: 
Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A sequence
Method: single particle / : Li X, Zuber PK, Loughran G, Bhatt PR, Alquraish F, Ramakrishnan V, Firth AE, Atkins JF

EMDB-72835: 
UDPG bound P2Y14 Receptor in complex with Gi
Method: single particle / : Fay JF, Che T

EMDB-72836: 
MRS2905 bound P2Y14 Receptor in complex with Gi
Method: single particle / : Fay JF

EMDB-72837: 
P2Y14R bound to MRS2905 (local refinement)
Method: single particle / : Fay JF

EMDB-72838: 
P2Y14R bound to UDPG (local refinement)
Method: single particle / : Fay JF

EMDB-63715: 
Cryo-EM structure of the human TRPA1 ion channel in complex with crotalphine.
Method: single particle / : Kang MM, Zhang YM, Ding XF, Wang LJ, Sun WY, Jiang H, Chen D, Xu JF, Pang XY

EMDB-63720: 
Cryo-EM structure of the human TRPA1 ion channel in ligand-free state.
Method: single particle / : Kang MM, Zhang YM, Ding XF, Wang LJ, Sun WY, Jiang H, Chen D, Xu JF, Pang XY

EMDB-43797: 
Local refinement of 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43798: 
Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43799: 
Local refinement of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43800: 
Global reconstruction of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43801: 
Local refinement of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43802: 
Global reconstruction of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43803: 
Local refinement of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43804: 
Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43805: 
Local refinement of 5-HT2AR bound to Mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43806: 
Global reconstruction of 5-HT2AR bound to mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43807: 
Local refinement of 5-HT2AR bound to psilocin in complex with a mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43808: 
Global reconstruction of 5-HT2AR bound to psilocin in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43809: 
Local refinement of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43810: 
Global reconstruction of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-39688: 
BA.2.86 RBD protein in complex with ACE2.
Method: single particle / : Wang YJ, Zhang X, Sun L

EMDB-39689: 
Structure of BA.2.86 spike protein in complex with ACE2.
Method: single particle / : Wang YJ, Zang X, Sun L

EMDB-39690: 
Structure of JN.1 RBD protein in complex with ACE2.
Method: single particle / : Wang YJ, Zhang X, Sun L

EMDB-39691: 
The JN.1 spike protein (S) in complex with ACE2.
Method: single particle / : Wang YJ, Zhang X, Sun L

EMDB-41895: 
(N3Occluded Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41896: 
(N3Occluded Local ABC1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41898: 
(N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41901: 
(N3Occluded Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41902: 
(N3Occluded Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42180: 
(V17) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41717: 
(N3Shifted Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41719: 
(N3Shifted Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41722: 
(N3Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41723: 
(N3Shifted Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41724: 
(N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41726: 
(N3Shifted Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42177: 
(Local CORE2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42178: 
(Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42179: 
(Composite) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41900: 
(Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41980: 
(Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41981: 
(Local hNBD1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-38342: 
Structure of EBV LMP1 dimer
Method: single particle / : Gao P, Huang JF

EMDB-38343: 
Structure of EBV LMP1 oligomer
Method: single particle / : Gao P, Huang JF

EMDB-35192: 
A cryoEM structure of the dimer of (S)-carbonyl reductase II
Method: single particle / : Li YH, Wang C, Zhang RZ, Xu Y, Hunt JF

EMDB-33989: 
Cryo-EM structure of the N-terminal domain of hMCM8/9 and HROB
Method: single particle / : Zheng JF, Weng ZF, Liu YF

EMDB-32346: 
Cryo-EM structure of gMCM8/9 helicase
Method: single particle / : Zheng JF, Weng ZF, Liu YF

EMDB-33241: 
Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex
Method: single particle / : Yang Y, Kang HJ, Gao RG, Wang JJ, Han GW, DiBerto JF, Wu LJ, Tong JH, Qu L, Wu YR, Pileski R, Li XM, Zhang XC, Zhao SW, Kenakin T, Wang Q, Stevens RC, Peng W, Roth BL, Rao ZH, Liu ZJ

EMDB-32497: 
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (focused refinement on Fab-RBD)
Method: single particle / : Zeng JW
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