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TitleMechanism of dual pharmacological correction and potentiation of human CFTR
Journal, issue, pagesTo Be Published
Publish dateAug 25, 2023 (structure data deposition date)
AuthorsWang C / Yang Z / Loughlin BJ / Xu H / Veit G / Vorobiev S / Clarke OB / Jiang F / Li Y / Singh S ...Wang C / Yang Z / Loughlin BJ / Xu H / Veit G / Vorobiev S / Clarke OB / Jiang F / Li Y / Singh S / Rich Z / Menten ER / Grassucci RA / Wang W / Mezzell A / Fu Z / Wong K / Wetmore DR / Sutton RB / Brouillette CG / Urbatsch IL / Kappes JC / Lukacs GL / Frank J / Hunt JF / Cohen BM
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.82 - 3.57 Å
Structure data

EMDB-41717: (N3Shifted Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.22 Å

EMDB-41719: (N3Shifted Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.57 Å

EMDB-41722: (N3Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.55 Å

EMDB-41723: (N3Shifted Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.43 Å

EMDB-41724: (N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.4 Å

EMDB-41726: (N3Shifted Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.32 Å

EMDB-41980: (Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 2.82 Å

EMDB-41981: (Local hNBD1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.06 Å

EMDB-42177: (Local CORE2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.06 Å

EMDB-42178: (Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.05 Å

EMDB-42179: (Composite) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 2.82 Å

Source
  • Homo sapiens (human)

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