EMDB-53976: Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop...

Basic information

Entry

Database: EMDB / ID: EMD-53976

• Title: Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A sequence
• Map data: Sharpened, masked map (using B-factor of -10 and provided mask)

Sample

• Complex: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human)
  • Complex: 40S subunit
    • Complex: 40S subunit proteins
      • Protein or peptide: x 34 types
    • Complex: 18S rRNA
      • RNA: x 1 types
  • Complex: 60S subunit
    • Complex: 60 subunit proteins
      • Protein or peptide: x 44 types
    • Complex: 5S, 5.8S, 28S rRNAs
      • RNA: x 2 types
  • Complex: P- and E-site tRNAs and nascent polypeptide chain
    • Protein or peptide: x 1 types
    • RNA: x 2 types
  • RNA: x 1 types
  • Protein or peptide: x 2 types
• RNA: x 1 types
• Ligand: x 6 types

• Keywords: Translation / Recoding / Nascent peptide / Foot-and-mouth disease virus / F2A / StopGo / RIBOSOME

Function / homology

Function:

[histone H4]-N-methyl-L-lysine20 N-methyltransferase / histone H4K20me methyltransferase activity / regulation of macromolecule metabolic process / L-peptidase / [histone H4]-lysine20 N-methyltransferase / histone H4K20 monomethyltransferase activity / translation termination factor activity / translation release factor complex / cytoplasmic translational termination / symbiont-mediated perturbation of host chromatin organization / regulation of translational termination / protein methylation / ribosomal subunit / translation release factor activity, codon specific / S-adenosyl-L-methionine binding / translation release factor activity / sequence-specific mRNA binding / peptidyl-tRNA hydrolase activity / nuclear-transcribed mRNA catabolic process, nonsense-mediated decay / positive regulation of double-strand break repair via nonhomologous end joining / laminin receptor activity / Protein hydroxylation / Eukaryotic Translation Termination / ubiquitin ligase inhibitor activity / 90S preribosome / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / positive regulation of signal transduction by p53 class mediator / pericentric heterochromatin / translational termination / phagocytic cup / protein-RNA complex assembly / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / rough endoplasmic reticulum / laminin binding / ribosomal small subunit export from nucleus / translation regulator activity / gastrulation / MDM2/MDM4 family protein binding / cytosolic ribosome / class I DNA-(apurinic or apyrimidinic site) endonuclease activity / DNA-(apurinic or apyrimidinic site) lyase / ribosomal large subunit biogenesis / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / positive regulation of apoptotic signaling pathway / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / picornain 3C / maturation of SSU-rRNA / T=pseudo3 icosahedral viral capsid / small-subunit processome / host cell cytoplasmic vesicle membrane / spindle / Regulation of expression of SLITs and ROBOs / cytoplasmic ribonucleoprotein granule / ribonucleoside triphosphate phosphatase activity / rRNA processing / positive regulation of canonical Wnt signaling pathway / rhythmic process / antimicrobial humoral immune response mediated by antimicrobial peptide / nucleoside-triphosphate phosphatase / heparin binding / regulation of translation / large ribosomal subunit / channel activity / ribosome binding / virus receptor activity / ribosomal small subunit biogenesis / ribosomal small subunit assembly / ribosomal large subunit assembly / 5S rRNA binding / small ribosomal subunit / small ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / monoatomic ion transmembrane transport / methylation / clathrin-dependent endocytosis of virus by host cell / cytosolic large ribosomal subunit / killing of cells of another organism / defense response to Gram-negative bacterium / perikaryon / cytoplasmic translation / cell differentiation / tRNA binding / RNA helicase activity / mitochondrial inner membrane / negative regulation of translation / rRNA binding / postsynaptic density / structural constituent of ribosome / viral protein processing / host cell endoplasmic reticulum membrane / ribosome / translation / ribonucleoprotein complex / cell division / RNA-directed RNA polymerase / cysteine-type endopeptidase activity / viral RNA genome replication / DNA repair / RNA-directed RNA polymerase activity

Domain/homology:

Suv4-20 family, animal / Histone-lysine N-methyltransferase Suv4-20/Set9 / Histone-lysine N-methyltransferase, N-terminal domain / Histone-lysine N-methyltransferase (EC 2.1.1.43) family profile. / RLI, domain 1 / RLI1 / RNase L inhibitor RLI-like, possible metal-binding domain / Possible Fer4-like domain in RNase L inhibitor, RLI / Peptidase C28, foot-and-mouth virus L-proteinase / Foot-and-mouth virus L-proteinase / Aphthovirus leader protease (L(pro)) domain profile. / Foot-and-mouth disease virus VP1 coat / Capsid protein VP4, Picornavirus / Viral protein VP4 subunit / Peptide chain release factor eRF1/aRF1 / eRF1, domain 1 / eRF1 domain 2 / eRF1 domain 2 / eRF1 domain 1/Pelota-like / eRF1 domain 3 / eRF1, domain 2 superfamily / eRF1 domain 1 / eRF1 domain 3 / eRF1_1 / Capsid protein VP4 superfamily, Picornavirus / 4Fe-4S binding domain / Helicase/polymerase/peptidase polyprotein, Calicivirus-type / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / : / 40S ribosomal protein SA / 40S ribosomal protein SA, C-terminal domain / 40S ribosomal protein SA C-terminus / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Ubiquitin-like protein FUBI / SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain / SET domain / Ribosomal protein L30e / 50S ribosomal protein L10, insertion domain superfamily / SET domain profile. / SET domain superfamily / SET domain / Ribosomal L15/L27a, N-terminal / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal protein L23 / Ribosomal protein L2, archaeal-type / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein L1, conserved site / Ribosomal protein L1 signature. / Ribosomal protein L1 / metallochaperone-like domain / TRASH domain / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein L1, 3-layer alpha/beta-sandwich / : / Ribosomal protein S12e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S12e / Ribosomal protein L29e / Ribosomal L29e protein family / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein L27e, conserved site / Ribosomal protein L1-like / Ribosomal protein L1/ribosomal biogenesis protein / Ribosomal protein L1p/L10e family / Ribosomal protein L27e signature. / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein S2, eukaryotic / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L19, eukaryotic / S27a-like superfamily / Ribosomal protein L10e, conserved site / : / Ribosomal protein L10e signature. / Ribosomal protein L6e signature. / Ribosomal protein L44e signature. / 40S Ribosomal protein S10 / Ribosomal protein L19/L19e conserved site

Component:

Small ribosomal subunit protein eS32 / 40S ribosomal protein S26 / Small ribosomal subunit protein eS24 / Ribosomal protein L36a / Large ribosomal subunit protein eL28 / Ribosomal protein L32 / Small ribosomal subunit protein eS19 / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein uS4 / Ribosomal protein L18 / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Small ribosomal subunit protein eS12 / ATP-binding cassette sub-family E member 1 / Large ribosomal subunit protein eL29 / Small ribosomal subunit protein uS9 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein RACK1 / Ubiquitin-ribosomal protein eS31 fusion protein / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL1 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein uS15 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL24 / Small ribosomal subunit protein eS1 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL30 / Small ribosomal subunit protein eS7 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein eL14 / Small ribosomal subunit protein uS12 / Large ribosomal subunit protein eL15 / Small ribosomal subunit protein eS10 / Small ribosomal subunit protein uS11 / Large ribosomal subunit protein uL14 / Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein / Small ribosomal subunit protein eS25 / Large ribosomal subunit protein eL30 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein eS28 / Small ribosomal subunit protein eS8 / Small ribosomal subunit protein eS4 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL3 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein eS6 / Small ribosomal subunit protein eS21 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein uS17 / Large ribosomal subunit protein eL22 / Large ribosomal subunit protein uL2 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL36 / Large ribosomal subunit protein eL20 / Small ribosomal subunit protein eS17 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein uL13 / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL34 / Large ribosomal subunit protein eL19 / Small ribosomal subunit protein eS27 / Large ribosomal subunit protein eL38 / Small ribosomal subunit protein uS19 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS5 / Ubiquitin-ribosomal protein eL40 fusion protein / Large ribosomal subunit protein uL18 / Eukaryotic peptide chain release factor subunit 1 / Genome polyprotein / Large ribosomal subunit protein eL37

• Biological species: Oryctolagus cuniculus (rabbit) / Foot-and-mouth disease virus SAT 2 / Homo sapiens (human)
• Method: single particle reconstruction / cryo EM / Resolution: 2.65 Å
• Authors: Li X / Zuber PK / Loughran G / Bhatt PR / Alquraish F / Ramakrishnan V / Firth AE / Atkins JF

Funding support

United Kingdom, European Union, 4 items

Organization	Grant number	Country
Medical Research Council (MRC, United Kingdom)	MC_U105184332	United Kingdom
Wellcome Trust	WT096570	United Kingdom
European Molecular Biology Organization (EMBO)	ALTF 937-2022	European Union
European Molecular Biology Organization (EMBO)	ALTF 778-2021	European Union

• Citation: Journal: Proc Natl Acad Sci U S A / Year: 2026; Title: Molecular architecture and diversity of StopGo/2A translational recoding.; Authors: Xueyan Li / Philipp K Zuber / Gary Loughran / Pramod R Bhatt / Fatema Alquraish / V Ramakrishnan / Andrew E Firth / John F Atkins / ; Abstract: Viral 2A sequences trigger a cotranslational peptide bond formation "skipping" event, termed "StopGo," to generate two separate proteins from a single open reading frame without classical termination. To investigate the mechanism of StopGo, we determined the cryo-EM structure of a mammalian ribosome positioned at the foot-and-mouth disease virus 2A (F2A) site. The structure shows how interactions between the F2A nascent chain (NC) and the ribosomal exit tunnel induce a conformational change in the peptidyl transferase center that precludes further translation elongation but instead pre-exposes the P-tRNA:F2A-NC ester bond for hydrolysis and NC release. Additionally, we bioinformatically characterized variation and host association across nearly 10,000 StopGo sequences identified in virus genomes. We expanded the canonical core motif to (D/G/C/N)(V/I)ExNPGP and identified additional rare but functional variants. We also revealed several distinct upstream motifs that we showed biochemically to be important for StopGo activity. Interestingly, although StopGo is known to be functionally active in plants, we found no evidence for natural utilization of StopGo by plant viruses. Overall, these findings provide valuable insights into a unique translation recoding mechanism, and lay foundations for further optimization of multigene expression in biotechnology.

History

Deposition	Jun 10, 2025	-
Header (metadata) release	Jan 21, 2026	-
Map release	Jan 21, 2026	-
Update	Feb 18, 2026	-
Current status	Feb 18, 2026	Processing site: PDBe / Status: Released

Map

• File: Download / File: emd_53976.map.gz / Format: CCP4 / Size: 824 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
• Annotation: Sharpened, masked map (using B-factor of -10 and provided mask)
• Voxel size: X=Y=Z: 0.702 Å

Density

Contour Level	By AUTHOR: 0.006
Minimum - Maximum	-0.01367463 - 0.04821608
Average (Standard dev.)	0.00025634875 (±0.0015933315)

• Symmetry: Space group: 1

Details

EMDB XML:

Map geometry	Axis order X Y Z Origin 0 0 0 Dimensions 600 600 600 Spacing 600 600 600
Cell	A=B=C: 421.2 Å α=β=γ: 90.0 °

Supplemental data

Mask #1

• File: emd_53976_msk_1.map

Additional map: Unsharpened map from 3D refinement

• File: emd_53976_additional_1.map
• Annotation: Unsharpened map from 3D refinement

Additional map: Map sharpened according to local resolution

• File: emd_53976_additional_2.map
• Annotation: Map sharpened according to local resolution

Half map: Half map 1

• File: emd_53976_half_map_1.map
• Annotation: Half map 1

Half map: Half map 2

• File: emd_53976_half_map_2.map
• Annotation: Half map 2

Sample components

Entire : Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of ...

• Entire: Name: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human)

Components

• Complex: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human)
  • Complex: 40S subunit
    • Complex: 40S subunit proteins
      • Protein or peptide: Small ribosomal subunit protein eS27
      • Protein or peptide: Small ribosomal subunit protein eS28
      • Protein or peptide: Ubiquitin-ribosomal protein eS31 fusion protein
      • Protein or peptide: 40S ribosomal protein eS30
      • Protein or peptide: eS26
      • Protein or peptide: Small ribosomal subunit protein RACK1
      • Protein or peptide: Small ribosomal subunit protein uS14
      • Protein or peptide: Small ribosomal subunit protein uS2
      • Protein or peptide: 40S ribosomal protein S3a
      • Protein or peptide: 40S ribosomal protein S2
      • Protein or peptide: Small ribosomal subunit protein uS3
      • Protein or peptide: 40S ribosomal protein S4
      • Protein or peptide: Small ribosomal subunit protein uS7
      • Protein or peptide: 40S ribosomal protein S6
      • Protein or peptide: Small ribosomal subunit protein eS7
      • Protein or peptide: 40S ribosomal protein S8
      • Protein or peptide: Small ribosomal subunit protein uS4
      • Protein or peptide: eS10
      • Protein or peptide: Small ribosomal subunit protein uS17
      • Protein or peptide: Small ribosomal subunit protein eS12
      • Protein or peptide: Small ribosomal subunit protein uS15
      • Protein or peptide: Small ribosomal subunit protein uS11
      • Protein or peptide: Small ribosomal subunit protein uS19
      • Protein or peptide: Small ribosomal subunit protein uS9
      • Protein or peptide: Small ribosomal subunit protein eS17
      • Protein or peptide: Small ribosomal subunit protein uS13
      • Protein or peptide: 40S ribosomal protein eS19
      • Protein or peptide: Small ribosomal subunit protein uS10
      • Protein or peptide: Small ribosomal subunit protein eS21
      • Protein or peptide: Small ribosomal subunit protein uS8
      • Protein or peptide: 40S ribosomal protein S23
      • Protein or peptide: 40S ribosomal protein S24
      • Protein or peptide: Small ribosomal subunit protein eS25
      • Protein or peptide: Small ribosomal subunit protein eS32
    • Complex: 18S rRNA
      • RNA: 18S rRNA
  • Complex: 60S subunit
    • Complex: 60 subunit proteins
      • Protein or peptide: 60S ribosomal protein L6
      • Protein or peptide: 60S ribosomal protein L7
      • Protein or peptide: Large ribosomal subunit protein eL8
      • Protein or peptide: 60S ribosomal protein L9
      • Protein or peptide: Large ribosomal subunit protein uL2
      • Protein or peptide: 60S ribosomal protein L10
      • Protein or peptide: Ribosomal protein L3
      • Protein or peptide: 60S ribosomal protein L11
      • Protein or peptide: Large ribosomal subunit protein uL4
      • Protein or peptide: Large ribosomal subunit protein uL18
      • Protein or peptide: Large ribosomal subunit protein eL13
      • Protein or peptide: 60S ribosomal protein L14
      • Protein or peptide: Ribosomal protein L15
      • Protein or peptide: Large ribosomal subunit protein uL13
      • Protein or peptide: Large ribosomal subunit protein uL22
      • Protein or peptide: eL18
      • Protein or peptide: 60S ribosomal protein L34
      • Protein or peptide: Ribosomal protein L19
      • Protein or peptide: Large ribosomal subunit protein eL20
      • Protein or peptide: 60S ribosomal protein L21
      • Protein or peptide: 60S ribosomal protein L22
      • Protein or peptide: Ribosomal protein L23
      • Protein or peptide: Ribosomal protein L24
      • Protein or peptide: Large ribosomal subunit protein uL23
      • Protein or peptide: Ribosomal protein L26
      • Protein or peptide: 60S ribosomal protein L27
      • Protein or peptide: 60S ribosomal protein L27a
      • Protein or peptide: 60S ribosomal protein L29
      • Protein or peptide: 60S ribosomal protein L30
      • Protein or peptide: 60S ribosomal protein L31
      • Protein or peptide: Ribosomal protein L32
      • Protein or peptide: 60S ribosomal protein L35a
      • Protein or peptide: 60S ribosomal protein L35
      • Protein or peptide: Large ribosomal subunit protein eL36
      • Protein or peptide: Ribosomal protein L37
      • Protein or peptide: 60S ribosomal protein L38
      • Protein or peptide: 60S ribosomal protein L39-like
      • Protein or peptide: Ubiquitin-ribosomal protein eL40 fusion protein
      • Protein or peptide: Ribosomal protein L36a
      • Protein or peptide: 60S ribosomal protein L37a
      • Protein or peptide: [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B
      • Protein or peptide: Large ribosomal subunit protein uL10
      • Protein or peptide: 60S ribosomal protein L12
      • Protein or peptide: Ribosomal protein uL1
    • Complex: 5S, 5.8S, 28S rRNAs
      • RNA: 5S rRNA
      • RNA: 5.8S rRNA
  • Complex: P- and E-site tRNAs and nascent polypeptide chain
    • Protein or peptide: Choriogonadotropin subunit beta variant 1,Genome polyprotein,Genome polyprotein
    • RNA: E-site tRNA-Pro
    • RNA: P-site tRNA-Gly
  • RNA: mRNA containing F2A sequence
  • Protein or peptide: Eukaryotic peptide chain release factor subunit 1
  • Protein or peptide: ATP binding cassette subfamily E member 1
• RNA: 28S rRNA
• Ligand: MAGNESIUM ION
• Ligand: ZINC ION
• Ligand: POTASSIUM ION
• Ligand: SPERMIDINE
• Ligand: GUANOSINE-5'-TRIPHOSPHATE
• Ligand: IRON/SULFUR CLUSTER

Supramolecule #1: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of ...

• Supramolecule: Name: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human); type: complex / ID: 1 / Parent: 0 / Macromolecule list: #2-#3, #5-#34, #1, #35-#88; Details: Sample generated by in vitro translation of an F2A PGX mRNA in rabbit reticulocyte lysate and subsequent affinity purification via a FLAG tag in the nascent poly peptide chain
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #2: 40S subunit

• Supramolecule: Name: 40S subunit / type: complex / ID: 2 / Parent: 1 ; Macromolecule list: #2, #5, #8, #11, #14, #17, #20, #23, #31, #33, #35, #37, #39, #41, #43, #45, #47, #49, #51, #53, #55, #57, #59, #61, #63, #65-#66, #68, #70, #72, #74, #76, #78, #80, #82
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #3: 60S subunit

• Supramolecule: Name: 60S subunit / type: complex / ID: 3 / Parent: 1 ; Macromolecule list: #3, #6-#7, #9-#10, #12-#13, #15-#16, #18-#19, #22, #24, #26, #28, #30, #32, #34, #1, #36, #38, #40, #42, #44, #46, #48, #50, #52, #54, #56, #58, #60, #62, #64, #67, #69, #71, #73, #75, #77, #79, #81, #83-#86
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #4: P- and E-site tRNAs and nascent polypeptide chain

• Supramolecule: Name: P- and E-site tRNAs and nascent polypeptide chain / type: complex / ID: 4 / Parent: 1 / Macromolecule list: #21, #27, #29
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #5: 40S subunit proteins

• Supramolecule: Name: 40S subunit proteins / type: complex / ID: 5 / Parent: 2 ; Macromolecule list: #5, #8, #11, #14, #17, #20, #23, #31, #33, #35, #37, #39, #41, #43, #45, #47, #49, #51, #53, #55, #57, #59, #61, #63, #65-#66, #68, #70, #72, #74, #76, #78, #80, #82
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #6: 18S rRNA

• Supramolecule: Name: 18S rRNA / type: complex / ID: 6 / Parent: 2 / Macromolecule list: #2
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #7: 60 subunit proteins

• Supramolecule: Name: 60 subunit proteins / type: complex / ID: 7 / Parent: 3 ; Macromolecule list: #3, #6, #9, #12-#13, #15-#16, #18-#19, #22, #24, #26, #28, #30, #32, #34, #1, #36, #38, #40, #42, #44, #46, #48, #50, #52, #54, #56, #58, #60, #62, #64, #67, #69, #71, #73, #75, #77, #79, #81, #83-#86
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Supramolecule #8: 5S, 5.8S, 28S rRNAs

• Supramolecule: Name: 5S, 5.8S, 28S rRNAs / type: complex / ID: 8 / Parent: 3 / Macromolecule list: #7, #10
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)

Macromolecule #1: 60S ribosomal protein L34

• Macromolecule: Name: 60S ribosomal protein L34 / type: protein_or_peptide / ID: 1 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 13.326074 KDa

Sequence

String:

MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR PKVLMRLSKT KKHVSRAYGG SMCAKCVRD RIKRAFLIEE QKIVVKVLKA QAQSQKAK

UniProtKB: Large ribosomal subunit protein eL34

Macromolecule #3: 60S ribosomal protein L6

• Macromolecule: Name: 60S ribosomal protein L6 / type: protein_or_peptide / ID: 3 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 33.028336 KDa

Sequence

String:

MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL KQLSSGLLLV TGPLSLNRVP LRRTHQKFVI ATSTKIDISG VKIPKHLTDA YFKKKKLRKP RHQEGEIFDT EK EKYEITE QRKVDQKAVD SQILPKIKAV PQLQGYLRSV FALTNGVYPH KLVF

UniProtKB: Large ribosomal subunit protein eL6

Macromolecule #5: Small ribosomal subunit protein eS27

• Macromolecule: Name: Small ribosomal subunit protein eS27 / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 9.480186 KDa

Sequence

String:

MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH

UniProtKB: Small ribosomal subunit protein eS27

Macromolecule #6: 60S ribosomal protein L7

• Macromolecule: Name: 60S ribosomal protein L7 / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 29.51425 KDa

Sequence

String:

LFANNIREKK KVPAVPETLK KKRRNFAELK IKRLRKKFAQ KMLRKARRKL IYEKAKHYHK EYRQMYRTEI RMARMARKAG NFYVPAEPK LAFVIRIRGI NGVSPKVRKV LQLLRLRQIF NGTFVKLNKA SINMLRIVEP YIAWGYPNLK SVNELIYKRG Y GKINKKRI ALTDNTLIAR SLGKYNIICM EDLIHEIYTV GKHFKEANNF LWPFKLSSPR GGMKKKTTHF VEGGDAGNRE DQ INRLIRR MN

UniProtKB: Large ribosomal subunit protein uL30

Macromolecule #8: Small ribosomal subunit protein eS28

• Macromolecule: Name: Small ribosomal subunit protein eS28 / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 7.855052 KDa

Sequence

String:

MDTSRVQPIK LARVTKVLGR TGSQGQCTQV RVEFMDDTSR SIIRNVKGPV REGDVLTLLE SEREARRLR

UniProtKB: Small ribosomal subunit protein eS28

Macromolecule #9: Large ribosomal subunit protein eL8

• Macromolecule: Name: Large ribosomal subunit protein eL8 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 36.193461 KDa

Sequence

String:

MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQA LDRQTATQLL KLAHKYRPET K QEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK GK ARLGRLV HRKTCTTVAF TQVNSEDKGA LAKLVEAIRT NYNDRYDEIR RHWGGNVLGP KSVARIAKLE KAKAKELATK LG

UniProtKB: Large ribosomal subunit protein eL8

Macromolecule #11: Ubiquitin-ribosomal protein eS31 fusion protein

• Macromolecule: Name: Ubiquitin-ribosomal protein eS31 fusion protein / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 9.445211 KDa

Sequence

String:

AKKRKKKSYT TPKKNKHKRK KVKLAVLKYY KVDENGKISR LRRECPSDEC GAGVFMASHF DRHYCGKCCL TYCFNKPEDK

UniProtKB: Ubiquitin-ribosomal protein eS31 fusion protein

Macromolecule #12: 60S ribosomal protein L9

• Macromolecule: Name: 60S ribosomal protein L9 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 21.871418 KDa

Sequence

String:

MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QADE

UniProtKB: Large ribosomal subunit protein uL6

Macromolecule #13: Large ribosomal subunit protein uL2

• Macromolecule: Name: Large ribosomal subunit protein uL2 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 28.103855 KDa

Sequence

String:

MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV VAGGGRIDKP ILKAGRAYHK YKAKRNCWPR VRGVAMNPVE HPFGGGN(V5N)QH IGKPSTIRRD APAGRKVG L IAARRTGRLR GTKTVQEKEN

UniProtKB: Large ribosomal subunit protein uL2

Macromolecule #14: 40S ribosomal protein eS30

• Macromolecule: Name: 40S ribosomal protein eS30 / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 6.741048 KDa

Sequence

String:

KVHGSLARVG KVRGQTLKVA KQEKKKKRTG RAKRRMQYNR RFVNVVPTFG KKKGPNANS

UniProtKB: Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

Macromolecule #15: 60S ribosomal protein L10

• Macromolecule: Name: 60S ribosomal protein L10 / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.643057 KDa

Sequence

String:

MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS KKWGFTKFNA DEFEDMVAEK RLIPDGCGVK YIPNRGPLDK WRALHS

UniProtKB: Large ribosomal subunit protein uL16

Macromolecule #16: Ribosomal protein L3

• Macromolecule: Name: Ribosomal protein L3 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 46.120996 KDa

Sequence

String:

MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVS QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKT(HIC)RG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINP LGGFVHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTVEEKK AFMGPLKKDR IAKEEGA

UniProtKB: Large ribosomal subunit protein uL3

Macromolecule #17: eS26

• Macromolecule: Name: eS26 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 13.047532 KDa

Sequence

String:

MTKKRRNNGR AKKGRGHVQP IRCTNCARCV PKDKAIKKFV IRNIVEAAAV RDISEASVFD AYVLPKLYVK LHYCVSCAIH SKVVRNRSR EARKDRTPPP RFRPAGAAPR PPPKPM

UniProtKB: 40S ribosomal protein S26

Macromolecule #18: 60S ribosomal protein L11

• Macromolecule: Name: 60S ribosomal protein L11 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 20.288465 KDa

Sequence

String:

MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKV REYELRKNNF SDTGNFGFGI QEHIDLGIKY DPSIGIYGLD FYVVLGRPGF SIADKKRRTG CIGAKHRISK E EAMRWFQQ KYDGIILPGK

UniProtKB: Large ribosomal subunit protein uL5

Macromolecule #19: Large ribosomal subunit protein uL4

• Macromolecule: Name: Large ribosomal subunit protein uL4 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 46.283703 KDa

Sequence

String:

(ACE)ACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARI PRV RGGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVED KV EGYKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC VIYNEDNGIV KAFRNIPGIT LLNVTKLN I LKLAPGGHVG RFCIWTESAF RKLDDLYGTW RKAASLKSNY NLPMHKMLNT DLSRILKSPE IQRALRAPRK KIHRRVLKK NPLKNLRIML KLNPYAKTMR RNTILRQARN HKLRVERAAA ALAAKSDPKE APAKKKPVVG KKKKPVVGRK AAAAKKPAAD KKAADKRAG PEDKKPAA

UniProtKB: Large ribosomal subunit protein uL4

Macromolecule #20: Small ribosomal subunit protein RACK1

• Macromolecule: Name: Small ribosomal subunit protein RACK1 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 35.115652 KDa

Sequence

String:

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRL WDLTTGTTTR RFVGHTKDVL SVAFSSDNRQ IVSGSRDKTI KLWNTLGVCK YTVQDESHSE WVSCVRFSPN S SNPIIVSC GWDKLVKVWN LANCKLKTNH IGHTGYLNTV TVSPDGSLCA SGGKDGQAML WDLNEGKHLY TLDGGDIINA LC FSPNRYW LCAATGPSIK IWDLEGKIIV DELKQEVIST SSKAEPPQCT SLAWSADGQT LFAGYTDNLV RVWQVTIGTR

UniProtKB: Small ribosomal subunit protein RACK1

Macromolecule #21: Choriogonadotropin subunit beta variant 1,Genome polyprotein,Geno...

• Macromolecule: Name: Choriogonadotropin subunit beta variant 1,Genome polyprotein,Genome polyprotein; type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Foot-and-mouth disease virus SAT 2
• Molecular weight: Theoretical: 20.020877 KDa
• Recombinant expression: Organism: Oryctolagus cuniculus (rabbit)

Sequence

String:

MDYKDHDGDY KDHDIDYKDD DDKSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTATRVLQG VLPALPQVTV FLPFRCATT AGPQPPTTLE VLFQGPGGSI LPKIKWAHTI SNQVSRTPPG LCHQGKRAEL YCPRALLPAY THAGGDRFDA P IGVAKQLL NFDLLKLAGD VESNPG

UniProtKB: Genome polyprotein

Macromolecule #22: Large ribosomal subunit protein uL18

• Macromolecule: Name: Large ribosomal subunit protein uL18 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 34.424777 KDa

Sequence

String:

MFVKVVKNKA YFKRYQVKFR RRREGKTDYY ARKRLVIQDK NKYNTPKYRM IVRVTNRDII CQIAYARIEG DMIVCAAYAH ELPKYGVKV GLTNYAAAYC TGLLLARRLL NRFGMDKIYE GQVEVTGDEY NVESIDGQPG AFTCYLDAGL ARTTTGNKVF G ALKGAVDG GLSIPHSTKR FPGYDSESKE FNAEVHRKHI MGQNVADYMR YLMEEDEDAY KKQFSQYIKN NVTPDMMEEM YK KAHAAIR ENPVYEKKPK REVKKKRWNR PKMSLAQKKD RVAQKKASFL RAQERAAES

UniProtKB: Large ribosomal subunit protein uL18

Macromolecule #23: Small ribosomal subunit protein uS14

• Macromolecule: Name: Small ribosomal subunit protein uS14 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 6.690821 KDa

Sequence

String:

MGHQQLYWSH PRKFGQGSRS CRVCSNRHGL IRKYGLNMCR QCFRQYAKDI GFIKLD

UniProtKB: Small ribosomal subunit protein uS14

Macromolecule #24: Large ribosomal subunit protein eL13

• Macromolecule: Name: Large ribosomal subunit protein eL13 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.331723 KDa

Sequence

String:

MAPSRNGMIL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ ARARRIAPRP AAGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLVLFPR KPSAPKKGDS SAEELKLATQ LTGPVMPIRN V FKKEKARV ITEEEKNFKA FASLRMARAN ARLFGIRAKR AKEAAEQDVE KKK

UniProtKB: Large ribosomal subunit protein eL13

Macromolecule #26: 60S ribosomal protein L14

• Macromolecule: Name: 60S ribosomal protein L14 / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 23.870549 KDa

Sequence

String:

MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG KKAAAQKAPA QKAPAQKAAG QKAAQPPKAQ KGQKPPAQKA PAPKASGKKA

UniProtKB: Large ribosomal subunit protein eL14

Macromolecule #28: Ribosomal protein L15

• Macromolecule: Name: Ribosomal protein L15 / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.207285 KDa

Sequence

String:

MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG RKSRGLGKGH KFHHTIGGSR RAAWRRRNTL QLHRYR

UniProtKB: Large ribosomal subunit protein eL15

Macromolecule #30: Large ribosomal subunit protein uL13

• Macromolecule: Name: Large ribosomal subunit protein uL13 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 23.533299 KDa

Sequence

String:

MAEGQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY RKKKQLMRLR KQAEKNVEKK ISKFTDVLKT HGLLV

UniProtKB: Large ribosomal subunit protein uL13

Macromolecule #31: Small ribosomal subunit protein uS2

• Macromolecule: Name: Small ribosomal subunit protein uS2 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 32.822828 KDa

Sequence

String:

(ACE)SGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL AARAIVAIEN PADVSV ISS RNTGQRAVLK FAAATGATPI AGRFTPGTFT NQIQAAFREP RLLVVTDPRA DHQPLTEASY VNLPTIALCN TDSPLRY VD IAIPCNNKGA HSVGLMWWML AREVLRMRGT ISREHPWEVM PDLYFYRDPE EIEKEEQAAA EKAVTKEEFQ GEWTAPAP E FTATQPEVAD WSEGVQVPSV PIQQFPTEDW SAQPATEDWS AAPTAQATEW VGTTTEWS

UniProtKB: Small ribosomal subunit protein uS2

Macromolecule #32: Large ribosomal subunit protein uL22

• Macromolecule: Name: Large ribosomal subunit protein uL22 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 21.444221 KDa

Sequence

String:

MVRYSLDPEN PTKSCKSRGS NLRVHFKNTR ETAQAIKGMH IRKATKYLKD VTLKKQCVPF RRYNGGVGRC AQAKQWGWTQ GRWPKKSAE FLLHMLKNAE SNAELKGLDV DSLVIEHIQV NKAPKMRRRT YRAHGRINPY MSSPCHIEMI LTEKEQIVPK P EEEVAQKK KISQKKLKKQ KLMARE

UniProtKB: Large ribosomal subunit protein uL22

Macromolecule #33: 40S ribosomal protein S3a

• Macromolecule: Name: 40S ribosomal protein S3a / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 30.002061 KDa

Sequence

String:

MAVGKNKRLT KGGKKGAKKK VVDPFSKKDW YDVKAPAMFN IRNIGKTLVT RTQGTKIASD GLKGRVFEVS LADLQNDEVA FRKFKLITE DVQGKNCLTN FHGMDLTRDK MCSMVKKWQT MIEAHVDVKT TDGYLLRLFC VGFTKKRNNQ IRKTSYAQHQ Q VRQIRKKM MEIMTREVQT NDLKEVVNKL IPDSIGKDIE KACQSIYPLH DVFVRKVKML KKPKFELGKL MELHGEGSSS GK ATGDETG AKVERADGYE PPVQESV

UniProtKB: Small ribosomal subunit protein eS1

Macromolecule #34: eL18

• Macromolecule: Name: eL18 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 21.699688 KDa

Sequence

String:

MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR LFMSRTNRPP LSLSRMIRKM KLPGRENKTA VVVGTVTDD VRVQEVPKLK VCALRVTSRA RSRILKAGGK ILTFDQLALD SPKGRGTVLL SGPRKGREVY RHFGKAPGTP H SHTKPYVR SKGRKFERAR GRRASRGYKN

UniProtKB: Ribosomal protein L18

Macromolecule #35: 40S ribosomal protein S2

• Macromolecule: Name: 40S ribosomal protein S2 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 31.285426 KDa

Sequence

String:

MADDAGAAGG PGGPGGPGMG GRGGFRGGFG SGIRGRGRGR GRGRGRGRGA RGGKAEDKEW LPVTKLGRLV KDMKIKSLEE IYLFSLPIK ESEIIDFFLG AALKDEVLKI MPVQKQTRAG QRTRFKAFVA IGDYNGHVGL GVKCSKEVAT AIRGAIILAK L SIVPVRRG YWGNKIGKPH TVPCKVTGRC GSVLVRLIPA PRGTGIVSAP VPKKLLMMAG IDDCYTSARG CTATLGNFAK AT FDAISKT YSYLTPDLWK ETVFTKSPYQ EFTDHLVKTH TRVSVQRTQA PAVATT

UniProtKB: Small ribosomal subunit protein uS5

Macromolecule #36: Ribosomal protein L19

• Macromolecule: Name: Ribosomal protein L19 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 23.535281 KDa

Sequence

String:

MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ARKRREERLQ AKKEEIIKTL SKEEETKK

UniProtKB: Large ribosomal subunit protein eL19

Macromolecule #37: Small ribosomal subunit protein uS3

• Macromolecule: Name: Small ribosomal subunit protein uS3 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 26.715344 KDa

Sequence

String:

MAVQISKKRK FVADGIFKAE LNEFLTRELA EDGYSGVEVR VTPTRTEIII LATRTQNVLG EKGRRIRELT AVVQKRFGFP EGSVELYAE KVATRGLCAI AQAESLRYKL LGGLAVRRAC YGVLRFIMES GAKGCEVVVS GKLRGQRAKS MKFVDGLMIH S GDPVNYYV DTAVRHVLLR QGVLGIKVKI MLPWDPSGKI GPKKPLPDHV SIVEPKDEIL PTTPISEQKG GKPEPPAMPQ PV PTA

UniProtKB: Small ribosomal subunit protein uS3

Macromolecule #38: Large ribosomal subunit protein eL20

• Macromolecule: Name: Large ribosomal subunit protein eL20 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 20.749391 KDa

Sequence

String:

MKASGTLREY KVVGRCLPTP KSPAPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE IVYCGQVFEK SPLRVKNFGI WLRYDSRSG THNMYREYRD LTTAGAVTQC YRDMGARHRA RAHSIQVMKV EEMAAARCRR PAVKQFHDSR IRFPLPHRVL R RQHKPRFS AKRPNTFF

UniProtKB: Large ribosomal subunit protein eL20

Macromolecule #39: 40S ribosomal protein S4

• Macromolecule: Name: 40S ribosomal protein S4 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 29.654869 KDa

Sequence

String:

MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDV ISIDKTGENF RLIYDTKGRF AVHRITPEEA KYKLCKVRKI FVGTKGIPHL VTHDARTIRY PDPLIKVNDT I QIDLETGK ITDFIKFDTG NLCMVTGGAN LGRIGVITNR ERHPGSFDVV HVKDANGNSF ATRLSNIFVI GKGNKPWISL PR GKGIRLT IAEERDKRLA AKQSSG

UniProtKB: Small ribosomal subunit protein eS4

Macromolecule #40: 60S ribosomal protein L21

• Macromolecule: Name: 60S ribosomal protein L21 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 18.609988 KDa

Sequence

String:

MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK TGRVYNVTQH AVGIVVNKQV KGKILAKRI NVRIEHIKHS KSRDSFLKRV KENDQKKKEA KEKGTWVQLK RQPAPPREAH FVRTNGKEPE LLEPIPYEFM A

UniProtKB: Large ribosomal subunit protein eL21

Macromolecule #41: Small ribosomal subunit protein uS7

• Macromolecule: Name: Small ribosomal subunit protein uS7 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 22.913453 KDa

Sequence

String:

MTEWETAAPA VAETPDIKLF GKWSTDDVQI NDISLQDYIA VKEKYAKYLP HSAGRYAAKR FRKAQCPIVE RLTNSMMMHG RNNGKKLMT VRIVKHAFEI IHLLTGENPL QVLVNAIINS GPREDSTRIG RAGTVRRQAV DVSPLRRVNQ AIWLLCTGAR E AAFRNIKT IAECLADELI NAAKGSSNSY AIKKKDELER VAKSNR

UniProtKB: Small ribosomal subunit protein uS7

Macromolecule #42: 60S ribosomal protein L22

• Macromolecule: Name: 60S ribosomal protein L22 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.756909 KDa

Sequence

String:

MAPVKKLVAK GGKKKKQVLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN GKAGNLGGGA VTIERSKSKI TVTSEVPFSK RYLKYLTKK YLKKNNLRDW LRVVANSKES YELRYFQINQ DEEEEEDED

UniProtKB: Large ribosomal subunit protein eL22

Macromolecule #43: 40S ribosomal protein S6

• Macromolecule: Name: 40S ribosomal protein S6 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 28.751906 KDa

Sequence

String:

MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRT GERKRKSVRG CIVDANLSVL NLVIVKKGEK DIPGLTDTTV PRRLGPKRAS RIRKLFNLSK EDDVRQYVVR K PLNKEGKK PRTKAPKIQR LVTPRVLQHK RRRIALKKQR TKKNKEEAAE YAKLLAKRMK EAKEKRQEQI AKRRRLSSLR AS TSKSESS QK

UniProtKB: Small ribosomal subunit protein eS6

Macromolecule #44: Ribosomal protein L23

• Macromolecule: Name: Ribosomal protein L23 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.892505 KDa

Sequence

String:

MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYR RKDGVFLYFE DNAGVIVNNK GEMKGSAITG PVAKECADLW PRIASNAGSI A

UniProtKB: Large ribosomal subunit protein uL14

Macromolecule #45: Small ribosomal subunit protein eS7

• Macromolecule: Name: Small ribosomal subunit protein eS7 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 22.168914 KDa

Sequence

String:

MFSSSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELNITAAKE IEVGGGRKAI IIFVPVPQLK SFQKIQVRLV RELEKKFSG KHVVFIAQRR ILPKPTRKSR TKNKQKRPRS RTLTAVHDAI LEDLVFPSEI VGKRIRVKLD GSRLIKVHLD K AQQNNVEH KVETFSGVYK KLTGKDVNFE FPEFQL

UniProtKB: Small ribosomal subunit protein eS7

Macromolecule #46: Ribosomal protein L24

• Macromolecule: Name: Ribosomal protein L24 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.825111 KDa

Sequence

String:

MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLAD IMAKRNQKPE VRKAQREQAI RAAKEAKKAK QASKKTAMAA AKAPTKAAPK QKIVKPVKVS APRVGGKR

UniProtKB: Large ribosomal subunit protein eL24

Macromolecule #47: 40S ribosomal protein S8

• Macromolecule: Name: 40S ribosomal protein S8 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.263387 KDa

Sequence

String:

MGISRDNWHK RRKTGGKRKP YHKKRKYELG RPAANTKIGP RRIHTVRVRG GNKKYRALRL DVGNFSWGSE CCTRKTRIID VVYNASNNE LVRTKTLVKN CIVLIDSTPY RQWYESHYAL PLGRKKGAKL TPEEEEILNK KRSKKIQKKY DERKKNAKIS S LLEEQFQQ GKLLACIASR PGQCGRADGY VLEGKELEFY LRKIKARKGK

UniProtKB: Small ribosomal subunit protein eS8

Macromolecule #48: Large ribosomal subunit protein uL23

• Macromolecule: Name: Large ribosomal subunit protein uL23 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.768246 KDa

Sequence

String:

MAPKAKKEAP APPKVEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

UniProtKB: Large ribosomal subunit protein uL23

Macromolecule #49: Small ribosomal subunit protein uS4

• Macromolecule: Name: Small ribosomal subunit protein uS4 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 22.641564 KDa

Sequence

String:

MPVARSWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAAREL LTLDEKDPRR LFEGNALLRR LVRIGVLDE GKMKLDYILG LKIEDFLERR LQTQVFKLGL AKSIHHARVL IRQRHIRVRK QVVNIPSFIV RLDSQKHIDF S LRSPYGGG RPGRVKRKNA KKGQGGAGAG DDEEED

UniProtKB: Small ribosomal subunit protein uS4

Macromolecule #50: Ribosomal protein L26

• Macromolecule: Name: Ribosomal protein L26 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.303363 KDa

Sequence

String:

MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGKYKEET IEKMQE

UniProtKB: Large ribosomal subunit protein uL24

Macromolecule #51: eS10

• Macromolecule: Name: eS10 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 18.933846 KDa

Sequence

String:

MLMPKKNRIA IYELLFKEGV MVAKKDVHMP KHPELADKNV PNLHVMKAMQ SLKSRGYVKE QFAWRHFYWY LTNEGIQYLR DYLHLPPEI VPATLRRSRP ETGRPRPKGL EGERPARLTR GEADRDTYRR SAVPPGADKK AEAGAGSATE FQFRGGFGRG R GQPPQ

UniProtKB: Small ribosomal subunit protein eS10

Macromolecule #52: 60S ribosomal protein L27

• Macromolecule: Name: 60S ribosomal protein L27 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.835831 KDa

Sequence

String:

MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDI PLDKTVVNKD VFRDPALKRK ARREAKVKFE ERYKTGKNKW FFQKLRF

UniProtKB: Large ribosomal subunit protein eL27

Macromolecule #53: Small ribosomal subunit protein uS17

• Macromolecule: Name: Small ribosomal subunit protein uS17 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 18.468826 KDa

Sequence

String:

MADIQTERAY QKQPTIFQNK KRVLLGETGK EKLPRYYKNI GLGFKTPKEA IEGTYIDKKC PFTGNVSIRG RILSGVVTKM KMQRTIVIR RDYLHYIRKY NRFEKRHKNM SVHLSPCFRD VQIGDIVTVG ECRPLSKTVR FNVLKVTKAA GTKKQFQKF

UniProtKB: Small ribosomal subunit protein uS17

Macromolecule #54: 60S ribosomal protein L27a

• Macromolecule: Name: 60S ribosomal protein L27a / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 16.635551 KDa

Sequence

String:

MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGM(V5N)H HRINFDKYHP GYFGKVGMRH YHLKRNQSFC PTVNLD KLW TLVSEQTRVN AAKNKTGAAP IIDVVRSGYY KVLGKGKLPK QPVIVKAKFF SRRAEEKIKG VGGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

Macromolecule #55: Small ribosomal subunit protein eS12

• Macromolecule: Name: Small ribosomal subunit protein eS12 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.538987 KDa

Sequence

String:

MAEEGIAAGG VMDVNTALQE VLKTALIHDG LARGIREAAK ALDKRQAHLC VLASNCDEPM YVKLVEALCA EHQINLIKVD DNKKLGEWV GLCKIDREGK PRKVVGCSCV VVKDYGKESQ AKDVIEEYFK CKK

UniProtKB: Small ribosomal subunit protein eS12

Macromolecule #56: 60S ribosomal protein L29

• Macromolecule: Name: 60S ribosomal protein L29 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 26.721727 KDa

Sequence

String:

MAKS(MLZ)NHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALV KPK EVKPTIPKGV SRKLHRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGK AQ AETKPKAQAE TKPKAQAQAK PKAQAQGKPK AQAQGKPKAQ AQAKPKAQAQ AKPKAQAQTK PKAQATPAAP VPAQAPPK G AQPPAKAP

UniProtKB: Large ribosomal subunit protein eL29

Macromolecule #57: Small ribosomal subunit protein uS15

• Macromolecule: Name: Small ribosomal subunit protein uS15 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.259389 KDa

Sequence

String:

MGRMHAPGKG LSQSALPYRR SVPTWLKLTS DDVKEQIYKL AKKGLTPSQI GVILRDSHGV AQVRFVTGNK ILRILKSKGL APDLPEDLY HLIKKAVAVR KHLERNRKDK DAKFRLILIE SRIHRLARYY KTKRVLPPNW KYESSTASAL VA

UniProtKB: Small ribosomal subunit protein uS15

Macromolecule #58: 60S ribosomal protein L30

• Macromolecule: Name: 60S ribosomal protein L30 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 12.807065 KDa

Sequence

String:

MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQSLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYY RVCTLSIIDP GDSDIIRSMP EQTGEK

UniProtKB: Large ribosomal subunit protein eL30

Macromolecule #59: Small ribosomal subunit protein uS11

• Macromolecule: Name: Small ribosomal subunit protein uS11 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 16.302772 KDa

Sequence

String:

MAPRKGKEKK EEQVISLGPQ VAEGENVFGV CHIFASFNDT FVHVTDLSGK ETICRVTGGM KVKADRDESS PYAAMLAAQD VAQRCKELG ITALHIKLRA TGGNRTKTPG PGAQSALRAL ARSGMKIGRI EDVTPIPSDS TRRKGGRRGR RL

UniProtKB: Small ribosomal subunit protein uS11

Macromolecule #60: 60S ribosomal protein L31

• Macromolecule: Name: 60S ribosomal protein L31 / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.494938 KDa

Sequence

String:

MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLS RKRNEDEDSP NKLYTLVTYV PVTTFKNLQT VNVDEN

UniProtKB: Large ribosomal subunit protein eL31

Macromolecule #61: Small ribosomal subunit protein uS19

• Macromolecule: Name: Small ribosomal subunit protein uS19 / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.049182 KDa

Sequence

String:

MAEVEQKKKR TFRKFTYRGV DLDQLLDMSY EQLMQLYSAR QRRRLSRGLR RKQHSLLKRL RKAKKEAPPM EKPEVVKTHL RDMIILPEM VGSMVGVYNG KTFNQVEIKP EMIGHYLGEF SITYKPVKHG RPGIGATHSS RFIPLK

UniProtKB: Small ribosomal subunit protein uS19

Macromolecule #62: Ribosomal protein L32

• Macromolecule: Name: Ribosomal protein L32 / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.898932 KDa

Sequence

String:

MAALRPLVKP KIVKKRTKKF IRHQSDRYVK IKRNWRKPRG IDNRVRRRFK GQILMPNIGY GSNKKTKHML PSGFRKFLVH NVKELEVLL MCNKSYCAEI AHNVSSKNRK AIVERAAQLA IRVTNPNARL RSEENE

UniProtKB: Ribosomal protein L32

Macromolecule #63: Small ribosomal subunit protein uS9

• Macromolecule: Name: Small ribosomal subunit protein uS9 / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 16.477377 KDa

Sequence

String:

MPSKGPLQSV QVFGRKKTAT AVAHCKRGNG LIKVNGRPLE MIEPRTLQYK LLEPVLLLGK ERFAGVDIRV RVKGGGHVAQ IYAIRQSIS KALVAYYQKY VDEASKKEIK DILIQYDRTL LVADPRRCES KKFGGPGARA RYQKSYR

UniProtKB: Small ribosomal subunit protein uS9

Macromolecule #64: 60S ribosomal protein L35a

• Macromolecule: Name: 60S ribosomal protein L35a / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 12.580809 KDa

Sequence

String:

MSGRLWCKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFR SNLPAKAIGH RIRVMLYPSR I

UniProtKB: Large ribosomal subunit protein eL33

Macromolecule #65: Small ribosomal subunit protein eS17

• Macromolecule: Name: Small ribosomal subunit protein eS17 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.552119 KDa

Sequence

String:

MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVS ALDQEIIEVD PDTKEMLKLL DFGSLSNLQV TQPTVGMNFK TPRGAV

UniProtKB: Small ribosomal subunit protein eS17

Macromolecule #66: Small ribosomal subunit protein uS13

• Macromolecule: Name: Small ribosomal subunit protein uS13 / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.654619 KDa

Sequence

String:

(ACE)SLVIPEKFQ HILRVLNTNI DGRRKIAFAI TAIKGVGRRY AHVVLRKADI DLTKRAGELT EDEVERVITI MQNPRQ YKI PDWFLNRQKD VKDGKYSQVL ANGLDNKLRE DLERLKKIRA HRGLRHFWGL RVRGQHTKTT GRRGRTVGVS KKK

UniProtKB: Small ribosomal subunit protein uS13

Macromolecule #67: 60S ribosomal protein L35

• Macromolecule: Name: 60S ribosomal protein L35 / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.566599 KDa

Sequence

String:

MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTR AMRRRLNKHE ESLKTKKQQR KERLYPLRKY AVKA

UniProtKB: Large ribosomal subunit protein uL29

Macromolecule #68: 40S ribosomal protein eS19

• Macromolecule: Name: 40S ribosomal protein eS19 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.966432 KDa

Sequence

String:

MPGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYL(NMM)GGA GVGSMT KIY GGRQRNGVMP SHFSRGSKSV ARRVLQALEG LKMVEKDQDG GRKLTPQGQR DLDRIAGQVA AANKK

UniProtKB: Small ribosomal subunit protein eS19

Macromolecule #69: Large ribosomal subunit protein eL36

• Macromolecule: Name: Large ribosomal subunit protein eL36 / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 12.263834 KDa

Sequence

String:

MALRYPMAVG LNKGHKVTKN VSKPRHSRRR GRLTKHTKFV RDMIREVCGF APYERRAMEL LKVSKDKRAL KFIKKRVGTH IRAKRKREE LSSVLAAMRK AAAKKD

UniProtKB: Large ribosomal subunit protein eL36

Macromolecule #70: Small ribosomal subunit protein uS10

• Macromolecule: Name: Small ribosomal subunit protein uS10 / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 13.398763 KDa

Sequence

String:

MAFKDTGKTP VEPEVAIHRI RITLTSRNVK SLEKVCADLI RGAKEKNLKV KGPVRMPTKT LRITTRKTPC GEGSKTWDRF QMRIHKRLI DLHSPSEIVK QITSISIEPG VEVEVTIADA

UniProtKB: Small ribosomal subunit protein uS10

Macromolecule #71: Ribosomal protein L37

• Macromolecule: Name: Ribosomal protein L37 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 11.111032 KDa

Sequence

String:

MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

UniProtKB: Large ribosomal subunit protein eL37

Macromolecule #72: Small ribosomal subunit protein eS21

• Macromolecule: Name: Small ribosomal subunit protein eS21 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 9.165375 KDa

Sequence

String:

(ACE)MQNDAGEFV DLYVPRKCSA SNRIIGAKDH ASIQMNVAEV DKVTGRFNGQ FKTYAICGAI RRMGESDDSI LRLAKS DGI VSQNF

UniProtKB: Small ribosomal subunit protein eS21

Macromolecule #73: 60S ribosomal protein L38

• Macromolecule: Name: 60S ribosomal protein L38 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 8.238948 KDa

Sequence

String:

MPRKIEEIKD FLLTARRKDA KSVKIKKNKD NVKFKVRCSR YLYTLVITDK EKAEKLKQSL PPGLAVKELK

UniProtKB: Large ribosomal subunit protein eL38

Macromolecule #74: Small ribosomal subunit protein uS8

• Macromolecule: Name: Small ribosomal subunit protein uS8 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 14.865555 KDa

Sequence

String:

MVRMNVLADA LKSINNAEKR GKRQVLIRPC SKVIVRFLTV MMKHGYIGEF EIIDDHRAGK IVVNLTGRLN KCGVISPRFD VQLKDLEKW QNNLLPSRQF GFIVLTTSAG IMDHEEARRK HTGGKILGFF F

UniProtKB: Small ribosomal subunit protein uS8

Macromolecule #75: 60S ribosomal protein L39-like

• Macromolecule: Name: 60S ribosomal protein L39-like / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 6.455775 KDa

Sequence

String:

MSSHKTFRIK RFLAKKQKQN RPIPQWIWMK TGNKIRYNSK RRHWRRTKLG L

UniProtKB: Large ribosomal subunit protein eL39

Macromolecule #76: 40S ribosomal protein S23

• Macromolecule: Name: 40S ribosomal protein S23 / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.860666 KDa

Sequence

String:

MGKCRGLRTA RKLRSHRRDQ KWHDKQYKKA HLGTALKANP FGGASHAKGI VLEKVGVEAK Q(HY3)NSAIRKCV RVQLIK NGK KITAFVPNDG CLNFIEENDE VLVAGFGRKG HAVGDIPGVR FKVVKVANVS LLALYKGKKE RPRS

UniProtKB: Small ribosomal subunit protein uS12

Macromolecule #77: Ubiquitin-ribosomal protein eL40 fusion protein

• Macromolecule: Name: Ubiquitin-ribosomal protein eL40 fusion protein / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 6.241654 KDa

Sequence

String:

IIEPSLRQLA QKYNCDKMIC R(M3L)CYARLHPR AVNCRKKKCG HTNNLRPKKK VK

UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

Macromolecule #78: 40S ribosomal protein S24

• Macromolecule: Name: 40S ribosomal protein S24 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.463333 KDa

Sequence

String:

MNDTVTIRTR KFMTNRLLQR KQMVIDVLHP GKATVPKTEI REKLAKMYKT TPDVIFVFGF RTHFGGGKTT GFGMIYDSLD YAKKNEPKH RLARHGLYEK KKTSRKQRKE RKNRMKKVRG TAKANVGAGK KPKE

UniProtKB: Small ribosomal subunit protein eS24

Macromolecule #79: Ribosomal protein L36a

• Macromolecule: Name: Ribosomal protein L36a / type: protein_or_peptide / ID: 79 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 16.143188 KDa

Sequence

String:

MVAPIASHEE VRLGTAYILP LQAGSLSFRA DSVPAMVNVP KTRRTFCKKC GKHQPHKVTQ YKKGKDSLYA QGKRRYDRKQ SGYGGQT(MLZ)P IFRKKAKTTK KIVLRLECVE PNCRSKRMLA IKRCKHFELG GDKKRKGQVI QF

UniProtKB: Ribosomal protein L36a

Macromolecule #80: Small ribosomal subunit protein eS25

• Macromolecule: Name: Small ribosomal subunit protein eS25 / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 13.645028 KDa

Sequence

String:

PPKDDKKKKD AGKSAKKDKD PVNKSGGKAK KKKWSKGKVR DKLNNLVLFD KATYDKLCKE VPNYKLITPA VVSERLKIRG SLARAALQE LLSKGLIKLV SKHRAQVIYT RNTKGGDAPA AGEDA

UniProtKB: Small ribosomal subunit protein eS25

Macromolecule #81: 60S ribosomal protein L37a

• Macromolecule: Name: 60S ribosomal protein L37a / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 10.29935 KDa

Sequence

String:

MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKEL KDQ

UniProtKB: Large ribosomal subunit protein eL43

Macromolecule #82: Small ribosomal subunit protein eS32

• Macromolecule: Name: Small ribosomal subunit protein eS32 / type: protein_or_peptide / ID: 82 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 3.473451 KDa

Sequence

String:

MRAKWRKKRM RRLKRKRRKM RQRSK

UniProtKB: Small ribosomal subunit protein eS32

Macromolecule #83: [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B

• Macromolecule: Name: [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; type: protein_or_peptide / ID: 83 / Number of copies: 1 / Enantiomer: LEVO / EC number: [histone H4]-lysine20 N-methyltransferase
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 15.697503 KDa

Sequence

String:

(ACE)SAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVMKRRSGQ RKPATS YVR TTINKNARAT LSSIRHMIRK NKYRPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

UniProtKB: Large ribosomal subunit protein eL28

Macromolecule #84: Large ribosomal subunit protein uL10

• Macromolecule: Name: Large ribosomal subunit protein uL10 / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 34.380504 KDa

Sequence

String:

MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFV FTKEDLTEIR DMLLANKVPA AARAGAIAPC EVTVPAQNTG LGPEKTSFFQ ALGITTKISR GTIEILSDVQ L IKTGDKVG ASEATLLNML NISPFSFGLI IQQVFDNGSI YNPEVLDITE DTLHSRFLEG VRNVASVCLQ IGYPTVASVP HS IINGYKR VLALSVETEY TFPLAEKVKA FLADPSAFVA AAPVAAASTA APAAAAAAPA KVEAKEESEE SDEDMGFGLF D

UniProtKB: Large ribosomal subunit protein uL10

Macromolecule #85: 60S ribosomal protein L12

• Macromolecule: Name: 60S ribosomal protein L12 / type: protein_or_peptide / ID: 85 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 17.847619 KDa

Sequence

String:

MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRITV KLTIQNRQAQ IEVVPSASAL IIKALKEPP RDRKKQKNIK HSGNITFDEI VNIARQMRHR SLARELSGTI KEILGTAQSV GCNVDGRHPH DIIDDINSGA V ECPAS

UniProtKB: Large ribosomal subunit protein uL11

Macromolecule #86: Ribosomal protein uL1

• Macromolecule: Name: Ribosomal protein uL1 / type: protein_or_peptide / ID: 86 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.87541 KDa

Sequence

String:

MGDILSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS GTVRLKSTPR PKFSVCVLGD QQHCDEAKAV DIPHMDIEA LKKLNKNKKL VKKLAKKYDA FLASESLIKQ IPRILGPGLN KAGKFPSLLT HNENMVAKVD EVKSTIKFQM K KVLCLAVA VGHVKMTDDE LVYNIHLAVN FLVSLLKKNW QNVRALYIKS TMGKPQRLY

UniProtKB: Large ribosomal subunit protein uL1

Macromolecule #87: Eukaryotic peptide chain release factor subunit 1

• Macromolecule: Name: Eukaryotic peptide chain release factor subunit 1 / type: protein_or_peptide / ID: 87 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Homo sapiens (human)
• Molecular weight: Theoretical: 49.14377 KDa
• Recombinant expression: Organism: Escherichia coli BL21(DE3) (bacteria)

Sequence

String:

GPADDPSAAD RNVEIWKIKK LIKSLEAARG NGTSMISLII PPKDQISRVA KMLADEFGTA SNIKSRVNRL SVLGAITSVQ QRLKLYNKV PPNGLVVYCG TIVTEEGKEK KVNIDFEPFK PINTSLYLCD NKFHTEALTA LLSDDSKFGF IVIDGSGALF G TLQGNTRE VLHKFTVDLP KKHGRAAQSA LRFARLRMEK RHNYVRKVAE TAVQLFISGD KVNVAGLVLA GSADFKTELS QS DMFDQRL QSKVLKLVDI SYGGENGFNQ AIELSTEVLS NVKFIQEKKL IGRYFDEISQ DTGKYCFGVE DTLKALEMGA VEI LIVYEN LDIMRYVLHC QGTEEEKILY LTPEQEKDKS HFTDKETGQE HELIESMPLL EWFANNYKKF GATLEIVTDK SQEG SQFVK GFGGIGGILR YRVDFQGMEY QGGDDEFFDL DDY

UniProtKB: Eukaryotic peptide chain release factor subunit 1

Macromolecule #88: ATP binding cassette subfamily E member 1

• Macromolecule: Name: ATP binding cassette subfamily E member 1 / type: protein_or_peptide / ID: 88 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 67.405234 KDa

Sequence

String:

MADKLTRIAI VNHDKCKPKK CRQECKKSCP VVRMGKLCIE VTPQSKIAWI SETLCIGCGI CIKKCPFGAL SIVNLPSNLE KETTHRYCA NAFKLHRLPI PRPGEVLGLV GTNGIGKSTA LKILAGKQKP NLGKYDDPPD WQEILTYFRG SELQNYFTKI L EDDLKAII KPQYVDQIPK AAKGTVGSIL DRKDETKTQA IVCQQLDLTH LKERNVEDLS GGELQRFACA VVCIQKADIF MF DEPSSYL DVKQRLKAAI TIRSLINPDR YIIVVEHDLS VLDYLSDFIC CLYGVPSAYG VVTMPFSVRE GINIFLDGYV PTE NLRFRD ASLVFKVAET ANEEEVKKMC MYKYPGMKKK MGEFELAIVA GEFTDSEIMV MLGENGTGKT TFIRMLAGRL KPDE GGEVP VLNVSYKPQK ISPKSTGSVR QLLHEKIRDA YTHPQFVTDV MKPLQIENII DQEVQTLSGG ELQRVALALC LGKPA DVYL IDEPSAYLDS EQRLMAARVV KRFILHAKKT AFVVEHDFIM ATYLADRVIV FDGVPSKNTV ANSPQTLLAG MNKFLS QLE ITFRRDPNNY RPRINKLNSI KDVEQKKSGN YFFLDD

UniProtKB: ATP-binding cassette sub-family E member 1

Macromolecule #2: 18S rRNA

• Macromolecule: Name: 18S rRNA / type: rna / ID: 2 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 603.92825 KDa

Sequence

String:

UACCUGGUUG AUCCUGCCAG UAGCAU(A2M)UGC UUG(PSU)C(PSU)CAAA GAUUAAGCCA UGCAUGUCUA AGUACGCA C GGCCGGUACA GUGAAACUGC GAA(PSU)GGCUC(A2M) UUAAA(PSU)CAG(PSU) UAUGGU(OMU)CC(PSU) U (OMU)GGUCGCU CGCUCCUCUC CUACUUGGAU AACUGUGGUA (A2M)UUCUAG(A2M)GC UAA(OMU)A(OMC)AUGC CG ACGGGCG CUGACCCCCU UCGCGGGGGG GA(PSU)GCGUGCA (PSU)UUAUCAGAU CAAAACCAAC CCGGUCAGCC UCCCC CCGG CCCCGGCCGG GGGGGUGGGC GCCGGCGGCU UUGGUGACUC UAGAUAACCU CGGGCCGAUC GCACGCCCUC CGUGGC GGC GACGACCCAU UCGAACGUC(OMU) GCCCUAUCAA CUUUCGAUGG UAGUCGCCGU GCCUACCAUG GUGACCACGG G (PSU)GACGGGG AAUCAGGGUU CGAU(OMU)CCGGA GA(OMG)GGAGCCU GAGAAACGGC UACCACAU(OMC)C AAGG (A2M)AGGC AGCAGGCGCG C(A2M)AAUUACCC ACUCCCGACC CGGGGA(OMG)GU(A2M) GUGA(OMC)GAAAA AUAAC AAUA CAGGACUCUU UCGAGGCCCU GUAAUUGGAA UGAGUCCACU (PSU)UAA(A2M)UCCUU UAACGAGG(A2M)U CCAU UGGAG (OMG)GCAAGUC(PSU)G GUGCCAGCAG CCGCGG(OMU)AAU UCCAGCUCCA AUA(OMG)CGUA(PSU)A (PSU) UAAAGUUG CUGCAGUU(A2M)A AAAGCUCGUA G(PSU)U(OMG)GA(PSU)CUU GGGAGCGGGC GGGCGGUCCG CCGCGA GGC GAGCCACCGC CCGUCCCCGC CCCUUGCCUC UCGGCGCCCC CUCGAUGCUC UUAGCUGAGU GUCCCGCGGG GCCCGAA GC GUU(PSU)ACUUUG AAAAAA(PSU)(PSU)AG AGUG(PSU)UCAAA GCAGGCCCGA GCCGCCUGGA UACCGCAGCU AG GAA(PSU)AA(PSU) (OMG)GAAUAGGAC CGCGGUUCUA UUUUGUUGGU UUUCGGAACU GAGGCCAUGA UUAAGAGGGA C GGCCGGGG GCAUUCGUAU UGCGCCGCUA GAGGUGAAAU (PSU)CUUGGACCG GCGCAAGACG GACCAGAGCG AAAGCAUU (PSU) GCCAAGAAUG UUUUCAUUAA UCAAGA(A2M)CGA AAGUCGGAGG (PSU)(PSU)CGAAGACG A(PSU)CAGAUAC CGUCGUAGUU CCGACCA(PSU)AA ACGAUGCCGA CUGGCGAUGC GGCGGCGUUA UUCCCAUGAC CCGCCGGGCA GCUUCC GGG AAACCAAAGU CUUUGGGUUC CGGGGGGAGU A(PSU)GG(PSU)UGCAA AGCUGAAACU UAAAGGAAUU GACGGAAGG GCACCACCAG GAGUGGAGCC (PSU)GCGGC(PSU)UAA UU(PSU)GAC(B8N)CAA CACGGGAAAC CUCACCCGGC CCGG ACACG GACAGGA(OMU)UG ACAGAUUGAU AGCUCUUUCU CGAUUCCGUG GGUGG(OMU)G(OMG)UG CAUGGC(4AC)GU UCUUAGU(PSU)GG UGGAGCGAUU UGUCUGG(PSU)UA AUUCCGAUAA CGA(A2M)CGAGAC U(OMC)UGGCAUGC UAAC UAGUU ACGCGACCCC CGAGCGGUCG GCGUCCCCCA ACU(OMU)CU(PSU)A(OMG)A GGGACAAGUG GCGUUCAGCC ACC CGAGAU UGAGCAAUAA CA(OMG)GUCUGUG AUGCCCUUAG AUGUCCGGGG CUGCACGCGC GCUACACUGA CUGGCUCAGC GUGUGCCUA CCCUACGCCG GCAGGCGCGG GUAACCCGUU GAACCCCAUU CGUGAUGGGG AUCGGGGAUU GCAAUUAU (PSU) CCCCAUGAAC GAG(G7M)AAU(PSU)CC CAGUAAGUGC GGGUCAUAAG CUUGCGUUGA UU(A2M)AGUCCCU GCC CUU(PSU)GU ACACACCG(OMC)C CGUCGCUACU ACCGAUUGGA UGGUUUAGUG AGGCCCUCGG AUCGGCCCCG CCGGGG UCG GCCCACGGCC CUGGCGGAGC GCUGAGAAGA CGGUCGAACU (OMU)GACUAUCUA GAGGAAGUAA AAGUCGUA(6MZ) CAAGGUUUC(4AC) GUAGGUG(MA6)(MA6)C CUGCGGAAGG AUCAUUA

Macromolecule #4: 28S rRNA

• Macromolecule: Name: 28S rRNA / type: rna / ID: 4 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 1.5575195 MDa

Sequence

String:

CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGUGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ACUCCCCGGC GCCGCUCGUG GGGGGCCCAA GUCCUUCUGA UCGAGGCCCA GCCCGUGGAC GGUGUGAGGC CG GUAGCGG CCCCCGGCGC GCCGGGCCCG GGUCUUCCCG GAGUCGGGUU GCUUGGGAAU GCAGCCCAAA GCGGGUGGUA AAC UCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA CCGUAAGGGA AAGUUGAAAA GAACUUUGAA G (A2M)G(A2M)GAGUU CAAGAGGGCG UGAAACCGUU AAGAGGUAAA CGGGUGGGGU CCGCGCAGUC CGCCCGGAGG AUUC AACCC GGCGGCGUGG UCCGGCCGUG CCGGCGGUCU CGGCGGAUCU UUCCCGCUCC CCGUUCCUCC CGACCCCUCC ACCCG CUCC CCCUCCCCCG CCGGUCUUCU CCCUUCACGG GGGGUGGGUC GGCGGGUGCG GGGGUGGGCG GGCGGGGCCG GGGGUG GGG UCGGCGGGGG ACCGCCCCCC GGCCGGCGAC CGGCCGCCGC CGGGCGCAUU UCCACCGCGG CGGUGCGCCG CGACCGG CU CCGGGACGGC UGGGAAGGCC CCGGCGGGGA AGGUGGCCCG GGGGGACGCC UCGCCGCCGU CGUCCGCGGC GGCGGCGG G CGCGACCCCU CCCCGGGUGU UACAGCCCCG CCCCGGCAGC AGCAGCUCGC CGAAUCCCGG GGCCGAGGGA GCGAGACCU GUGUCGCCGC GCUCUCCCCC CUCCCGGCGC UCCCCCCCGC GGGGGUCCCC CGCGAGGGGG CUCCCCCCGC GGGGGCGCGC CGGUGUCGC CGCCCUCGCG GGCGCGGCAC GGGGGGGCCG GGCCGCCCCU CCCACGGCGC GACCGCUCUC CCGGCCCCCG C CGCCGCCU CUUCGGGCGU GCGGCGGGGG UGGGGCGGAC UGUCCCCAGU GCGCCCCGGG CGUGUCACGC CGUCGGGCUC GG GGGAGAA GUCGGCCACG GCGCGUCGCG CGCCUCCGCG UCCCCCCCUC GCCGUCUCCG GGCGGCGGGG GGGGGUUUCG GCG CGGUGU UCUCGGCGCG CGCGCGCGAG CGAGCGCACG GGGUCGGCGG CGAUGUCGGC UACCCACCCG ACCC(OMG)UCUUG (1MA)AAC(A2M)CGGA CCAAGGAGU(OMC) UAACACGUGC GCGAGUCGGG GGCUCGCACG AAAGCCGCCG UGGCGCAAU GAAGGUGAAG GCCGGCGGCG GCUUCCCGCC GUCGUCGGCC GAGGUGGGAU CCCGAGGCCC UUCCAGUCCG CCGAGGGCGC ACCACCGGC CCGUCUCGCC CGCCGCGCCG GGGAGGUGGA GCACGAGCGC ACGUGUUAGG ACCC(OMG)A(A2M)AGA UGG UGA(A2M)C(PSU) AUGCCUGGGC AGGGCGAAGC CAGAGGAAAC UCUGGUGGAG GUCCG(PSU)AGCG GUCCUGACGU GC AAAUCGG UCGUCCGACC UGGGUAUAG(OMG) GGCGAAAGAC UAAUCGAACC AUCUAGUAGC UGGUUCCCUC CGAAGUUUC CC(PSU)CAGGA(PSU)A GCUGGCGCUC UCGCAACCCC GCAGUUUUAU CCGGUAAAGC GAA(PSU)GAUUAG AGGUCUUG G GGCCGAAACG AUCUCAACC(PSU) A(PSU)(PSU)CUCAAAC UU(PSU)AAAUGGG UAAGAAGCCC GGCUCGCUGG CGU GGAGCC GGGCGUGGAA UGCGAGUGCC UAGUGGGCCA C(PSU)U(PSU)UGGUAA GC(A2M)GAACUGG CG(OMC)UGCGG G AUGAACCGAA CGCCGGGUUA AGGCGCCCGA UGCCGACGCU CAUCAGACCC CAGAAAAGGU GUUGGUUGAU AUAGACAGC AGGACGGUGG CCAUGGAAGU CGGAAUCCGC UAAGGAGUGU GUAACAACUC ACCUGCCGAA UCAACUAGCC CUGAAAAUGG AUGGCGCUG GAGCGUCGGG CCCAUACCCG GCCGUCGCUG GCAGUCGGCA GAGCGAGAAA GAGAGUGGAG CGCGCCGCGG G ACUCCCCC CGCGGGGGUC CCCGGCCACC CCCCCCCCGC GGACGCUACG CCGCGACGAG UAGGAGGGCC GCUGCGGUGA GC CUUGAAG CCUAGGGCGC GGGCCCGGGU GGAGCCGCCG CAGGUGCAGA U(OMC)UUGGUGGU AGU(A2M)(OMG)(OMC)A AA UAUUCAAACG AGAACUUUGA AGGCCGAAGU GG(A2M)GAAGGGU UCCAUG(OMU)GAA CAG(OMC)A(OMG)UUGA AC AUGGGUC AGUCGGUCCU GAGAGAUGGG CGAGCGCCGU UCCGAAGGGA CGGGCGAUGG CCUCCGUUGC CCUCAGCCGA (PSU)CGAAAGGG AGUCGGGUUC AGAUCCCCGA AUCCGGAGUG GCGGAGAUGG GCGCCGCGAG GCGUCCAGUG CGGUAAC GC GACCGAUCCC GGAGAAGCCG GCGGGAGCCC CGGGGAGAGU UCUCUU(PSU)UCU UUGUGAAGGG CAGGGCGCCC UGGA AUGGG UUCGCCCCGA GAGAGGGGCC CGUGCCUUGG AAAGCGUCGC GGUUCCGGCG GCGUCCGGUG AGCUCUCGCU GGCCC UUGA AAAUCCGGGG GAGAGGGUGU AAAUCUCGCG CCGGGCCGUA CCC(A2M)UAUCCG CAGCAGGUCU (OMC)CAAGGUG A AC(A2M)GCCUCUG G(OMC)AUGUUGGA ACAA(OMU)GUAGG UAAGGGAAGU CGGCAAGC(OMC)G GAUCCGUAAC UUC (OMG)GGAUA AGGAUUGGCU CUAAGGGCUG GGUCGGUCGG GCUGGGGCGC GAAGCGGGGC UGGGCGCGCG CCGCGGCUGG ACGAGGCGC CGCCGCCCCC CCCACGCCCG GGGCGCCCUC CCCCGGCCGG GUCCGCUCCC UCGCGCGCGC GUGCGCCGUG G CGCGCGCC GCGCGCGCGG CCGAGCCCCG UCUCCCUCCC CCCCUCUCCC CUCCCGGGGC GGGGUGCGGG GAGGGGCGGG CG GGGCCGU CGCUCGCCGC GCGUGCGCGU CGCUGCGCGU GCGCCGCGCG GGGGGUCCGG CGGGCCUCCG GACGGGGGCU CCG GGCACC CGGGCACCCG GGGGGCCGGC GGCGGCGGCG ACUCUGGACG CGAGCCGGGC CCUUCCCGUG GAUCGCCCCA GCUG CGGCG GGCGUCGCGG CCGCCCUCGG GGAGCCCGGC GGGCGCCGCG UGCGCGCGCG UGCGCGCCCG GGGUCGGGGG GGUGC GAGG CAGGGGAGGC CCUCUCUCCU CCUCCCCCAC CCCGGCGCCG CGGCGCCGCG CGUGCGCGCG CGGUCUCCCC CCGCCG GGU CCGCCCCCGG GGCCGCGGUU CCGCGCGGCG CCUCGCCUCG GCCGGCGCCU AGCAGCCGAC UUAGAACUGG UGCGGAC CA GG(OMG)GAAUCCG AC(PSU)G(PSU)UUAAU UAAAACAAAG CAUCGCGAAG GCCCGCGGCG GGUGUUGACG CGAUGU GAU U(PSU)CUGCC(OMC)AG UGCUCUGAAU G(PSU)CA(A2M)AGUGA (A2M)GAAAU(PSU)CAA (PSU)GAAGCGCG G(OMG)UAAACGGC GGGAG(PSU)A(A2M)C(PSU) A(PSU)GAC(PSU)C(PSU)CU UAAGGUAGC(5MC) AA(A2M)U GCCUC (OMG)UCAUCUAAU UAGUGA(OMC)GCG CAUGAA(UY1)GGA (PSU)GA(A2M)CGAG(A2M)U UCCCACUGU (OMC)CC(PSU)ACCUAC (PSU)A(PSU)CCAGCGA AACCAC(A2M)G(OMC)C AAGGGAACGG GCU(PSU)GG(OMC)G G AAUCAGCGG(OMG) GAAAGAAGAC CCUGUUGAGC (PSU)UGAC(OMU)CUAG UCUGGCACGG UGAA(OMG)AGACA UGA GAGGUG UAGAAUAAGU GGGAGGCCCC CGGCGCCCUC CCGCCCCCGC GAGGGGGCGG GGCGGGGUCC GCCGGCCUUG CGGG CCGCC GGUGAAAUAC CACUACUCUU AUCGUUUUUU CACUGACCCG GUGAGGCGGG GGGGCGAGCC CCGAGGGGCU CUCGC UUCU GGCGCCAAGC GCCGGGCCCC GUCGGUCCGC GCGGGCCGGC GGCGGCCGGG CGCGACCCGC UCCGGGGACA GUGCCA GGU GGGGAGUUUG ACUG(OMG)GGCGG UACACCUGUC AAACGGUA(6MZ)C GCAGG(OMU)(OMG)UCC UAAGGCGAGC U CAGGGAGG ACAGAAACCU CCCGUGGAGC AGAAGGGCAA AAGCUCGCUU GA(PSU)CU(PSU)GA(PSU)U UUCAG(OMU) ACG AA(PSU)ACAGACC GUGAAAGCGG GGCCUCACGA UCCUUCUGAG CUU(PSU)UGGGUU U(PSU)AAGCAGGA (OMG) GUGUCAGA AAAGUUACCA CAG(OMG)GAUAAC UGGC(PSU)UGUGG CGGCCAAGCG U(PSU)CA(PSU)AGCGA CG (PSU)CGCUUU UUGA(PSU)CCUU(5MC) GAUGUCGG(OMC)(PSU) CUUCCUAUCA UUG(PSU)GAAGCA GAAUUCACC AAGCGUU(OMG)GA U(OMU)(OMG)(PSU)UCACCC ACUAAUAGGG AACG(PSU)G(A2M)GCU GGG(UR3)U(PSU)AG A (OMC)CGUCGUGAG ACAGGU(PSU)AGU UUUACCCUAC UGAUG(A2M)UGUG (PSU)UG(PSU)UGCCAU GGUA(A2M) UCCU GCUCAGUACG AGAGGAACCG CAG(OMG)U(OMU)CA(OMG)A CAU(PSU)UGGUGU A(PSU)(OMG)UGCUUGG CU GAGGAGC CAAUGGGGCG AAGCUACCA(PSU) CUGUGGGAUU AUGAC(PSU)GAAC GCCUCUAAGU CAGAAUCCCG CCCAG GCGG AACGAUACGG CAGCGCCGAA GGAGCCUCGG UUGGCCUCGG AUAGCCGGUC CCCCGCCGUC CCCGCCGGCG GCCCGC GUC GUGCGUCCGC CUCGGCGGCG UGCGGCGCGC CCCCCGCCGC GCGUCGGGAC CGGGGUCCGG UGCGGAGAGC CCUUCGU CC CGGGAAAUGG GGCGCGGCCG GAAAGGGGGC CGCCCUCUCG CCCGUCACGC ACCGCACGUU CGUGGGGAAC CUGGCGCU A AACCA(PSU)UCGU AGACGACCUG CUUCUGGGUC GGGG(PSU)UUCGU ACG(PSU)AGCAGA GCAGCUCCCU CGCUGCG AU CUAUUGAAAG UCAGCCCUCG ACACAAGGGU UUGU

GENBANK: GENBANK: GBCN01009604.1

Macromolecule #7: 5S rRNA

• Macromolecule: Name: 5S rRNA / type: rna / ID: 7 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 38.346707 KDa

Sequence

String:

UCUACGGCCA UACCACCCUG AACGCGCCCG AUCUCGUCUG AUCUCGGAAG CUAAGCAGGG UCGGGCCUGG UUAGUACUUG GAUGGGAGA CCGCCUGGGA AUACCGGGUG CUGUAGGCUU

GENBANK: GENBANK: GBCM01014045.1

Macromolecule #10: 5.8S rRNA

• Macromolecule: Name: 5.8S rRNA / type: rna / ID: 10 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 50.809047 KDa

Sequence

String:

CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGC(PSU)GCGAG AAUUAAUG(PSU)G AA UU(OMG)CAGG ACACAUUGAU CAUCGACACU UCGAACGCAC UUGCGGCCCC GGGUUCCUCC CGGGGCUACG CCUGUCUGA GCGUCGCUUG

GENBANK: GENBANK: GBCN01009604.1

Macromolecule #25: mRNA containing F2A sequence

• Macromolecule: Name: mRNA containing F2A sequence / type: rna / ID: 25 / Number of copies: 1
• Source (natural): Organism: Foot-and-mouth disease virus SAT 2
• Molecular weight: Theoretical: 211.439672 KDa

Sequence

String:

GGCAACAACA ACAAACAUUU GCUUCUGACA CAACUGUGUU CACUAGCAAC CUCAAACAGA CACCAUGGAC UACAAAGACC ACGACGGUG AUUAUAAAGA UCACGACAUC GAUUACAAGG ACGACGACGA CAAGUCCAAG GAGCCGCUUC GGCCACGGUG C CGCCCCAU CAACGCCACC CUGGCUGUGG AGAAGGAGGG CUGCCCCGUG UGCAUCACCG UCAACACCAC CAUCUGUGCC GG CUACUGC CCCACCGCAA CCCGCGUGCU GCAGGGCGUC CUGCCGGCCC UGCCUCAGGU CACCGUAUUC UUACCGUUCC GGU GUGCAA CUACCGCCGG UCCGCAACCU CCCACCACAC UGGAGGUGCU CUUCCAGGGC CCUGGCGGCU CCAUAUUGCC CAAG AUCAA GUGGGCGCAU ACUAUCAGCA ACCAGGUCAG CAGAACGCCA CCUGGAUUGU GCCACCAGGG CAAGCGUGCA GAGUU GUAC UGCCCCCGUG CCCUGCUUCC CGCGUACACA CACGCGGGCG GCGACAGAUU CGACGCGCCU AUCGGCGUCG CGAAAC AGC UUUUGAACUU UGACCUGUUA AAGUUGGCGG GAGACGUUGA GUCCAACCCU GGGUGAUUCU UCUUCUCCGA CGUCAGG UC GAACUUCACC AAAUUGG

Macromolecule #27: E-site tRNA-Pro

• Macromolecule: Name: E-site tRNA-Pro / type: rna / ID: 27 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 24.102275 KDa

Sequence

String:

GCCCGGAUAG CUCAGCUGUA GAGCAUCAGA CUUUUAAUCU GAGGGUCCAG GGUUCAAGUC CCUGUUCGGG CGCCA

Macromolecule #29: P-site tRNA-Gly

• Macromolecule: Name: P-site tRNA-Gly / type: rna / ID: 29 / Number of copies: 1
• Source (natural): Organism: Oryctolagus cuniculus (rabbit)
• Molecular weight: Theoretical: 23.896344 KDa

Sequence

String:

GCG(OMC)CGCU(1MG)G UG(PSU)(1MA)G(H2U)GGUA UCAUGCAAGA (OMU)U(OMC)CCAU(OMU)CU UGCGAC (5MC)(5MC)G GG(5MU)UCG(1MA)UUC CCGGGCGGCG (5MC)ACCA

Macromolecule #89: MAGNESIUM ION

• Macromolecule: Name: MAGNESIUM ION / type: ligand / ID: 89 / Number of copies: 367 / Formula: MG
• Molecular weight: Theoretical: 24.305 Da

Macromolecule #90: ZINC ION

• Macromolecule: Name: ZINC ION / type: ligand / ID: 90 / Number of copies: 8 / Formula: ZN
• Molecular weight: Theoretical: 65.409 Da

Macromolecule #91: POTASSIUM ION

• Macromolecule: Name: POTASSIUM ION / type: ligand / ID: 91 / Number of copies: 37 / Formula: K
• Molecular weight: Theoretical: 39.098 Da

Macromolecule #92: SPERMIDINE

• Macromolecule: Name: SPERMIDINE / type: ligand / ID: 92 / Number of copies: 2 / Formula: SPD
• Molecular weight: Theoretical: 145.246 Da

Chemical component information

ChemComp-SPD:
SPERMIDINE

Macromolecule #93: GUANOSINE-5'-TRIPHOSPHATE

• Macromolecule: Name: GUANOSINE-5'-TRIPHOSPHATE / type: ligand / ID: 93 / Number of copies: 1 / Formula: GTP
• Molecular weight: Theoretical: 523.18 Da

Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

Macromolecule #94: IRON/SULFUR CLUSTER

• Macromolecule: Name: IRON/SULFUR CLUSTER / type: ligand / ID: 94 / Number of copies: 2 / Formula: SF4
• Molecular weight: Theoretical: 351.64 Da

Chemical component information

ChemComp-FS1:
IRON/SULFUR CLUSTER

Experimental details

Structure determination

• Method: cryo EM
• Processing: single particle reconstruction
• Aggregation state: particle

Sample preparation

• Concentration: 0.4 mg/mL

Buffer

pH: 7.4
Component:

Concentration	Name	Formula
50.0 mM	HEPES
100.0 mM	Potassium acetate	KOAc
5.0 mM	Magnesium acetate	Mg(OAc)2
1.0 mM	DTT

• Grid: Model: Quantifoil R1.2/1.3 / Material: GOLD / Mesh: 300 / Support film - Material: GRAPHENE OXIDE / Pretreatment - Type: GLOW DISCHARGE / Pretreatment - Time: 45 sec. / Pretreatment - Atmosphere: AIR
• Vitrification: Cryogen name: ETHANE / Chamber humidity: 100 % / Chamber temperature: 277 K / Instrument: FEI VITROBOT MARK II

Electron microscopy

• Microscope: TFS KRIOS
• Image recording: Film or detector model: GATAN K3 (6k x 4k) / Number grids imaged: 2 / Number real images: 22565 / Average exposure time: 1.2 sec. / Average electron dose: 40.0 e/Ų
• Electron beam: Acceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
• Electron optics: C2 aperture diameter: 50.0 µm / Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Cs: 2.7 mm / Nominal defocus max: 2.2 µm / Nominal defocus min: 1.0 µm / Nominal magnification: 105000
• Sample stage: Specimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER / Cooling holder cryogen: NITROGEN
• Experimental equipment: Model: Titan Krios / Image courtesy: FEI Company

Image processing

• Particle selection: Number selected: 544139 / Details: Particle picking using 2D template matching
• CTF correction: Software - Name: CTFFIND (ver. 4.1) / Type: PHASE FLIPPING AND AMPLITUDE CORRECTION

Startup model

Type of model: EMDB MAP
EMDB ID:

0194

Details: Low-pass filtered to 20 Angstroms

• Final reconstruction: Applied symmetry - Point group: C₁ (asymmetric) / Resolution.type: BY AUTHOR / Resolution: 2.65 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION (ver. 5.0) / Number images used: 49964
• Initial angle assignment: Type: MAXIMUM LIKELIHOOD / Software - Name: RELION (ver. 5.0)
• Final angle assignment: Type: MAXIMUM LIKELIHOOD / Software - Name: RELION (ver. 5.0)
• Final 3D classification: Software - Name: RELION (ver. 5.0)

Atomic model buiding 1

Initial model

PDB ID:

7o80

Chain - Source name: PDB / Chain - Initial model type: experimental model

• Refinement: Space: REAL / Protocol: FLEXIBLE FIT

Output model

PDB-9rhu:
Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A sequence