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Title(N3 Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Journal, issue, pagesTo Be Published
Publish dateSep 11, 2023 (structure data deposition date)
AuthorsWang C / Singh S / Loughlin BJ / Yang Z / Xu H / Veit G / Vorobiev S / Clarke OB / Jiang F / Li Y ...Wang C / Singh S / Loughlin BJ / Yang Z / Xu H / Veit G / Vorobiev S / Clarke OB / Jiang F / Li Y / Rich Z / Menten ER / Grassucci RA / Wang W / Mezzell A / Fu Z / Wong K / Wetmore DR / Sutton RB / Brouillette CG / Urbatsch IL / Kappes JC / Lukacs GL / Frank J / Hunt JF / Cohen BM
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.03 - 3.59 Å
Structure data

EMDB-41895: (N3Occluded Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.57 Å

EMDB-41896: (N3Occluded Local ABC1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.59 Å

EMDB-41898: (N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.43 Å

EMDB-41900: (Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.55 Å

EMDB-41901: (N3Occluded Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.03 Å

EMDB-41902: (N3Occluded Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.32 Å

EMDB-42180: (V17) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: EM (single particle) / Resolution: 3.35 Å

Source
  • Homo sapiens (human)

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