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Showing 1 - 50 of 71 items for (author: villagran & a)

EMDB-72649: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72656: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72751: 
LRRK2 asymmetric dimer
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72756: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 2)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72762: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 1)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72768: 
Leucine Rich Repeat Kinase 2 R1441C mutant (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72940: 
LRRK2 activated (flexible C-terminus)
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72941: 
Leucine Rich Repeat Kinase 2 bound to GDP (from GMPPNP data)
Method: single particle / : Villagran A, Bodrug T

EMDB-72978: 
Leucine Rich Repeat LRRK2 (GDP data)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-72982: 
Leucine Rich Repeat Kinase 2 active state (Apo state 3)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-73484: 
Focused refinement map on N-terminal half of LRRK2 GMPPNP (active)-Resolved EM
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73485: 
Focused refinement map on N-terminal half of LRRK2 bound to GMPPNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73487: 
LRRK2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73491: 
Focused refinement map on LRRK2 bound to GMPPNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73492: 
Focused refinement map on LRRK2 bound to GMPPNP (inactive) Resolve EM
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73495: 
Focused refinement map of LRRK2 APO state 2
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73496: 
Focused refinement map of LRRK2 APO state 1
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73497: 
Focused map of LRRK2 bound to G10 (top)
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-73499: 
Focused map of LRRK2 bound to G10 (WD40-DARPin)
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-73501: 
Focused map of LRRK2 R1441C (active)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-73502: 
Focused map of LRRK2 R1441C (active) ResolveEM
Method: single particle / : Villagran Suarez A, Bodrug T

PDB-9y7a: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9y7i: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ybl: 
LRRK2 asymmetric dimer
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ybp: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 2)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9yc8: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 1)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ycd: 
Leucine Rich Repeat Kinase 2 R1441C mutant (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ygt: 
Leucine Rich Repeat Kinase 2 bound to GDP (from GMPPNP data)
Method: single particle / : Villagran A, Bodrug T

EMDB-70604: 
Full-length LRRK2 autoinhibited
Method: single particle / : Villagran-Suarez AC, Bodrug T

EMDB-70981: 
Full length LRRK2 bound to G10 DARPin
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-70982: 
Full-length LRRK2 autonhibited (flexible)
Method: single particle / : Villagran-Suarez A, Bodrug T, Alegrio-Louro J, Leschziner A

EMDB-71012: 
Full LRRK2 (R1441C mutant) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72555: 
Full length LRRK2 after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72556: 
Full length LRRK2 (G2019S) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-73338: 
C-terminal LRRK2 bound to C12 DARPin
Method: single particle / : Sanz-Murillo M, Leschziner A

PDB-9om2: 
Full-length LRRK2 autoinhibited
Method: single particle / : Villagran-Suarez AC, Bodrug T

PDB-9oxh: 
Full length LRRK2 bound to G10 DARPin
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

PDB-9oxi: 
Full-length LRRK2 autonhibited (flexible)
Method: single particle / : Villagran-Suarez A, Bodrug T

PDB-9oya: 
Full LRRK2 (R1441C mutant) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9y67: 
Full length LRRK2 after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9y68: 
Full length LRRK2 (G2019S) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9yqk: 
C-terminal LRRK2 bound to C12 DARPin
Method: single particle / : Sanz-Murillo M, Leschziner A

EMDB-45592: 
13-pf microtubule from the LRRK2(I2020T) and MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45593: 
Focused refinement map of WD40:ARM/ANK interface from LRRK2(I2020T) MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45594: 
Full-length autoinhibited LRRK2(I2020T) co-polymerized with microtubules and MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45595: 
Full-length autoinhibited LRRK2 on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45596: 
Full-length autoinhibited LRRK2 on microtubules with GZD-824
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45591: 
Autoinhibited full-length LRRK2(I2020T) on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Villa E, Leschziner AE

PDB-9cho: 
Autoinhibited full-length LRRK2(I2020T) on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Villa E, Leschziner AE

EMDB-41709: 
Structure of C-terminal LRRK2 bound to MLi-2
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A
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