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Showing 1 - 50 of 86 items for (author: sexton & pm)

EMDB-71396:
Cryo-EM structure of the PAC1nR-VIP-Gs complex
Method: single particle / : Piper SJ, Lu J, Sexton P, Wootten D

EMDB-71397:
Cryo-EM structure of the PAC1sR-VIP-Gs complex
Method: single particle / : Piper SJ, Lu J, Sexton P, Wootten D

EMDB-71398:
Cryo-EM structure of the PAC1sR-PACAP27-Gs complex
Method: single particle / : Piper SJ, Sexton P, Wootten D

EMDB-47447:
Glucagon Like Peptide Receptor-1 (GLP1R) A316T mutant with GLP-1 peptide. Dominant negative Gs complex.
Method: single particle / : Deane-Alder K, Belousoff MJ, Wootten DL

EMDB-48424:
CGRP Receptor in complex with dC2_050
Method: single particle / : Cao J, Cary BP, Belousoff MJ, Wootten DL

EMDB-45087:
Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-phe1
Method: single particle / : Zhang X, Johnson R, Belousoff MJ, Danev R, Sexton PM, Wootten D

EMDB-45040:
Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-asp3
Method: single particle / : Zhang X, Johnson R, Belousoff MJ, Danev R, Sexton PM, Wootten D

EMDB-44760:
Human Amylin1 Receptor in complex with Gs and cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44796:
Human Amylin2 Receptor in Complex with Gs and Cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM, Johnson RM

EMDB-44904:
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44905:
Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation (repeat)
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44906:
Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44652:
Human Calcitonin Receptor in Complex with Gs and Cagrilintide Backbone (non-acylated) in bypass conformation
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM

EMDB-44653:
Human Calcitonin Receptor in Complex with Gs and Cagrilintide Backbone (non-acylated) in CT-like conformation
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM

EMDB-44678:
Human amylin1 Receptor in complex with Gs and Cagrilintide backbone (non-acylated)
Method: single particle / : Cao J, Belousoff MJ, Sexton PM, Wootten DL

EMDB-44898:
Human Amylin3 Receptor in complex with Gs and cagrilintide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-44907:
Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation (repeat)
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Sexton PM, Wootten DL

EMDB-47882:
Peptide 1 (GLP-1 (Aib16, ACPC18)) bound to GLP-1R/Gs complex
Method: single particle / : Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Wootten D, Sexton PM, Gellman SH

EMDB-47883:
Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 1)
Method: single particle / : Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Wootten D, Sexton PM, Gellman SH

EMDB-47884:
Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 2)
Method: single particle / : Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Wootten D, Sexton PM, Gellman SH

EMDB-44642:
Cholecystokinin 1 receptor (CCK1R) Y140A mutant, Gq chimera (mGsqi) complex
Method: single particle / : Cary BP, Harikumar KG, Zhao P, Desai AJ, Mobbs JM, Toufaily C, Furness SGB, Christopoulos A, Belousoff MJ, Wootten D, Sexton PM, Miller LJ

EMDB-44643:
Cholecystokinin 1 receptor (CCK1R) sterol 7M mutant, Gq chimera (mGsqi) complex
Method: single particle / : Harikumar KG, Zhao P, Cary BP, Xu X, Desai AJ, Mobbs JI, Toufaily C, Furness SGB, Christopoulos A, Belousoff MJ, Wootten D, Sexton PM, Miller LJ

EMDB-43877:
Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide
Method: single particle / : Cao J, Belousoff MJ, Wootten DL, Sexton PM

EMDB-42023:
GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.
Method: single particle / : Russell IC, Belousoff MJ, Sexton P

EMDB-29524:
Human M4 muscarinic acetylcholine receptor complex with Gi1 and xanomeline
Method: single particle / : Vuckovic Z, Mobbs JI, Glukhova A, Sexton PM, Danev R, Thal DM

EMDB-28758:
Calcitonin Receptor in complex with Gs and Pramlintide analogue peptide San45
Method: single particle / : Cao J, Sexton PM, Wootten DL, Belousoff MJ

EMDB-28759:
Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385
Method: single particle / : Cao J, Sexton PM, Wootten DL

EMDB-28810:
Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 (Cluster 5 conformation)
Method: single particle / : Cao J, Sexton PM, Wootten DL, Radostin D

EMDB-28812:
Amylin 3 Receptor in complex with Gs and Pramlintide analogue peptide San45
Method: single particle / : Cao J, Sexton PM, Wootten DL, Belousoff MJ

EMDB-29283:
Human PTH1R in complex with PTH(1-34) and Gs
Method: single particle / : Cary BP, Belousoff MJ, Piper SJ, Wootten D, Sexton PM

EMDB-29284:
Human PTH1R in complex with PTHrP and Gs
Method: single particle / : Cary BP, Belousoff MJ, Piper SJ, Wootten D, Sexton PM

EMDB-29285:
Human PTH1R in complex with Abaloparatide and Gs
Method: single particle / : Cary BP, Belousoff MJ, Piper SJ, Wootten D, Sexton PM

EMDB-29286:
Human PTH1R in complex with M-PTH(1-14) and Gs
Method: single particle / : Cary BP, Belousoff MJ, Piper SJ, Wootten D, Sexton PM

EMDB-29287:
Human PTH1R in complex with LA-PTH and Gs
Method: single particle / : Cary BP, Belousoff MJ, Piper SJ, Wootten D, Sexton PM

EMDB-27872:
Cryo-EM structure of the PAC1R-PACAP27-Gs complex
Method: single particle / : Piper SJ, Danev R, Sexton P, Wootten D

EMDB-27873:
Cryo-EM structure of the VPAC1R-PACAP27-Gs complex
Method: single particle / : Piper SJ, Belousoff MJ, Danev R, Sexton P, Wootten D

EMDB-27874:
Cryo-EM structure of the VPAC1R-VIP-Gs complex
Method: single particle / : Piper SJ, Danev R, Sexton P, Wootten D

EMDB-26180:
Calcitonin Receptor in complex with Gs and rat amylin peptide, CT-like state
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Wootten DL, Sexton PM

EMDB-26188:
Calcitonin Receptor in complex with Gs and salmon calcitonin peptide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Wootten DL, Sexton PM

EMDB-26197:
Human Amylin2 Receptor in complex with Gs and rat amylin peptide
Method: single particle / : Cao J, Belousoff MJ, Johnson RM, Wootten DL, Sexton PM

EMDB-26178:
Human Amylin1 Receptor in complex with Gs and rat amylin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-26179:
Human Amylin2 Receptor in complex with Gs and human calcitonin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-26184:
Calcitonin Receptor in complex with Gs and rat amylin peptide, bypass motif
Method: single particle / : Cao J, Belousoff MJ

EMDB-26190:
Calcitonin receptor in complex with Gs and human calcitonin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-26196:
Human Amylin1 Receptor in complex with Gs and salmon calcitonin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-26199:
Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-26208:
Human Amylin3 Receptor in complex with Gs and rat amylin peptide
Method: single particle / : Cao J, Belousoff MJ

EMDB-23425:
Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein
Method: single particle / : Wootten D, Sexton PM

EMDB-23436:
Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein
Method: single particle / : Wootten D, Sexton PM

EMDB-24805:
Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 1)
Method: single particle / : Cary BP, Gellman SH

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