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Showing 1 - 50 of 485 items for (author: seth & a)

EMDB-73122:
De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)
Method: single particle / : Mueller AU, Darst SA

EMDB-73123:
De novo initial transcribing RNA polymerase with pretranslocated 3-mer RNA / product complex (RPitc3)
Method: single particle / : Mueller AU, Darst SA

EMDB-73124:
de novo initial transcribing RNA polymerase with 5-mer RNA CCAUC (RPitc5a)
Method: single particle / : Mueller AU, Darst SA

EMDB-73125:
De novo initial transcribing RNA polymerase with 5-mer RNA AUCUA (RPitc5b)
Method: single particle / : Mueller AU, Darst SA

EMDB-73126:
De novo initial transcribing RNA polymerase with 9-mer RNA (RPitc9)
Method: single particle / : Mueller AU, Darst SA

EMDB-73127:
De novo initial transcribing RNA polymerase on T7A1 promoter (weak downstream)
Method: single particle / : Mueller AU, Darst SA

EMDB-73128:
De novo initial transcribing RNA polymerase on T7A1 promoter (empty channel)
Method: single particle / : Mueller AU, Darst SA

EMDB-73130:
RNA polymerase open complex on T7A1 promoter (RPo)
Method: single particle / : Mueller AU, Darst SA

EMDB-73131:
De novo initial transcribing RNA polymerase with sigma 70 region 1.1 bound (RPitc-s70_1.1)
Method: single particle / : Mueller AU, Darst SA

PDB-9ymu:
De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)
Method: single particle / : Mueller AU, Darst SA

PDB-9ymv:
De novo initial transcribing RNA polymerase with pretranslocated 3-mer RNA / product complex (RPitc3)
Method: single particle / : Mueller AU, Darst SA

PDB-9ymw:
De novo initial transcribing RNA polymerase with 5-mer RNA CCAUC (RPitc5a)
Method: single particle / : Mueller AU, Darst SA

PDB-9ymx:
De novo initial transcribing RNA polymerase with 5-mer RNA AUCUA (RPitc5b)
Method: single particle / : Mueller AU, Darst SA

PDB-9ymy:
De novo initial transcribing RNA polymerase with 9-mer RNA (RPitc9)
Method: single particle / : Mueller AU, Darst SA

PDB-9yn0:
De novo initial transcribing RNA polymerase with sigma 70 region 1.1 bound (RPitc-s70_1.1)
Method: single particle / : Mueller AU, Darst SA

EMDB-75279:
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75280:
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75281:
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75282:
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10ma:
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10mb:
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10mc:
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

PDB-10md:
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-72508:
BS3-crosslinked Smoothened/PKA-C complex
Method: single particle / : Liu G, Myers BR

EMDB-74330:
SMO/PKA-C complex, mixed prior to grid preparation
Method: single particle / : Liu G, Myers BR

EMDB-74331:
SMO/PKA-C complex in MSP1E3D1 nanodiscs
Method: single particle / : Liu G, Myers BR

EMDB-74332:
Disulfide-trapped SMO-L637C/PKA-C complex
Method: single particle / : Liu G, Myers BR

EMDB-74333:
EDC/Sulfo-NHS-crosslinked SMO/PKA-C complex
Method: single particle / : Liu G, Myers BR

EMDB-74334:
SMO/PKA-C complex, dual EDC/Sulfo-NHS and BS3 crosslinking
Method: single particle / : Liu G, Myers BR

EMDB-56885:
NorA bound to miniprotein I-23
Method: single particle / : Lamon G, Mishra P, Chazin-Gray A, Baker D, Traaseth NJ

PDB-28vj:
NorA bound to miniprotein I-23
Method: single particle / : Lamon G, Mishra P, Chazin-Gray A, Baker D, Traaseth NJ

EMDB-71770:
Structure of human serotonin transporter bound to small molecule zPZd in lipid nanodisc and NaCl
Method: single particle / : Billesboelle CB, Manglik A

EMDB-71775:
Locally-refined Mu-Opioid Receptor bound with novel compound 0505
Method: single particle / : Kim JY, Wu Y, Manglik A, Shoichet BK

PDB-9pns:
Structure of human serotonin transporter bound to small molecule zPZd in lipid nanodisc and NaCl
Method: single particle / : Billesboelle CB, Manglik A

PDB-9ppq:
Locally-refined Mu-Opioid Receptor bound with novel compound 0505 (3-[({[(1P)-1-(3-chlorophenyl)-1H-pyrazol-3-yl]methyl}amino)methyl]phenol)
Method: single particle / : Kim JY, Wu Y, Manglik A, Shoichet BK

EMDB-49835:
SARS-CoV-2 BA.1 S6P (HexaPro) + COV2-3835 Fab Local Refinement Map (RBD + Fv)
Method: single particle / : Ramamohan AR, Johnson NV, McLellan JS

PDB-9nvg:
Structure of SARS-CoV-2 BA.1 spike RBD bound to COV2-3835 Fab
Method: single particle / : Ramamohan AR, Johnson NV, McLellan JS

EMDB-72145:
Nucleotide-free structure of PmtCD in detergent LMNG
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

EMDB-72169:
Nucleotide-free structure of PmtCD in nanodisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

EMDB-72172:
Nucleotide-free structure of PmtCD in peptidisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

EMDB-72173:
ADP-bound structure of PmtCD in peptidisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

PDB-9q1y:
Nucleotide-free structure of PmtCD in detergent LMNG
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

PDB-9q2n:
Nucleotide-free structure of PmtCD in nanodisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

PDB-9q2q:
Nucleotide-free structure of PmtCD in peptidisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

PDB-9q2r:
ADP-bound structure of PmtCD in peptidisc
Method: single particle / : Worrall LJ, Li FKK, Hu J, Lazarski AC, Strynadka NCJ

EMDB-45286:
Cryo EM map of SARS-COV-2 (BQ 1.1) spike protein in complex with Fab COV2-3891 (2 open 1 close)
Method: single particle / : Binshtein E, Crowe JE

EMDB-45287:
Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
Method: single particle / : Binshtein E, Crowe JE

PDB-9c7s:
Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
Method: single particle / : Binshtein E, Crowe JE

EMDB-47692:
Off-pathway Mycobacterium tuberculosis transcription initiation promoter complex (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47695:
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 7-mer RNA and disordered Beta' Lid element (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

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Nobel Prize for mechanically activated and temperature-gated ion channels

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