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| Title | Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jul 31, 2025 (structure data deposition date) |
Authors | Gray JL / Ledger EVK / Suwatthee T / Lanyon-Hogg T / Burden TJ / Arvaniti K / Sefton A / Papagora LE / Clarke TB / Riley J ...Gray JL / Ledger EVK / Suwatthee T / Lanyon-Hogg T / Burden TJ / Arvaniti K / Sefton A / Papagora LE / Clarke TB / Riley J / Pinto EG / Cunningham F / Gilbert IH / Gray D / Wang D / Read KD / Traaseth NJ / Edwards A / Tate EW |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.52 Å |
| Structure data | EMDB-71880, PDB-9pv0: |
| Chemicals | ![]() PDB-1clb: |
| Source |
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Keywords | TRANSPORT PROTEIN/INHIBITOR / efflux pump / membrane protein / TRANSPORT PROTEIN-INHIBITOR complex |
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