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Showing all 47 items for (author: mathea & s)

EMDB-47004:
Focused refinement map on C-terminal half of LRRK2 (RoC-CORA domains)
Method: single particle / : Sanz-Murillo M, Leschziner A

EMDB-47006:
Structure of the C-terminal half of LRRK2 bound to RN277 (Type-II inhibitor)
Method: single particle / : Sanz-Murillo M, Leschziner A

EMDB-47025:
Focused refinement map on C-terminal half of LRRK2 bound to RN277 (CORB-Kinase-WD40 domains)
Method: single particle / : Sanz-Murillo M, Leschziner A

PDB-9dmi:
Structure of the C-terminal half of LRRK2 bound to RN277 (Type-II inhibitor)
Method: single particle / : Sanz-Murillo M, Leschziner A

EMDB-41806:
C-terminal LRRK2 bound to E11 DARPin
Method: single particle / : Sanz-Murillo M, Mathea S, Dederer V, Knapp S, Leschziner A

PDB-8u1b:
C-terminal LRRK2 bound to E11 DARPin
Method: single particle / : Sanz-Murillo M, Mathea S, Dederer V, Knapp S, Leschziner A

EMDB-41709:
Structure of C-terminal LRRK2 bound to MLi-2
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

EMDB-41728:
Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41753:
Structure of the C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41754:
Structure of C-terminal LRRK2 bound to MLi-2 (G2019S mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

EMDB-41756:
Structure of C-terminal half of LRRK2 bound to GZD-824
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41757:
Structure of full length LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41758:
Structure of C-terminal LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

EMDB-41759:
Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

EMDB-41794:
Structure of C-terminal half of LRRK2 (I2020T mutant) bound to GZD-824, Kinase-WD40
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41795:
Structure of C-terminal half of LRRK2 (I2020T mutant) bound to GZD-824, ROC-COR domain
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41797:
Structure of C-terminal half of LRRK2 (G2019S mutant) bound to GZD-824, ROC-COR domain
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41798:
Structure of C-terminal half of LRRK2 bound tp GZFD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41799:
Structure of C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant), Kinase-WD40
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41802:
Structure of C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8txz:
Structure of C-terminal LRRK2 bound to MLi-2
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

PDB-8tyq:
Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzb:
Structure of the C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzc:
Structure of C-terminal LRRK2 bound to MLi-2 (G2019S mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

PDB-8tze:
Structure of C-terminal half of LRRK2 bound to GZD-824
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzf:
Structure of full length LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzg:
Structure of C-terminal LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

PDB-8tzh:
Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

EMDB-27813:
Structure of monomeric LRRK1
Method: single particle / : Reimer JM, Mathea S, Chatterjee D, Knapp S, Leschziner AE

EMDB-27814:
Local refinement around RCKW of LRRK1
Method: single particle / : Reimer JM, Mathea S, Knapp S, Leschziner AE

EMDB-27815:
Local refinement of LRRK1 around the ROC-COR-kinase domains
Method: single particle / : Reimer JM, Mathea S, Knapp S, Leschziner AE

EMDB-27816:
Local refinement around kinase and WD40 domains of LRRK1
Method: single particle / : Reimer JM, Mathea S, Knapp S, Leschziner AE

EMDB-27817:
Structure of dimeric LRRK1
Method: single particle / : Reimer JM, Lin YX, Leschziner AE

EMDB-27818:
Symmetry expansion of dimeric LRRK1
Method: single particle / : Reimer JM, Lin YX, Leschziner AE

PDB-8e04:
Structure of monomeric LRRK1
Method: single particle / : Reimer JM, Mathea S, Chatterjee D, Knapp S, Leschziner AE

PDB-8e05:
Structure of dimeric LRRK1
Method: single particle / : Reimer JM, Lin YX, Leschziner AE

PDB-8e06:
Symmetry expansion of dimeric LRRK1
Method: single particle / : Reimer JM, Lin YX, Leschziner AE

EMDB-21250:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21306:
Cryo-EM map of the C-terminal half of Leucine Rich Repeat Kinase 2 as a monomer at 8.1 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21309:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a COR-COR domain dimer at 9.5 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21310:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a WD40-WD40 domain dimer at 13.4 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21311:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a COR-COR domain dimer in the presence of the MLi-2 kinase inhibitor at 9.0 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

EMDB-21312:
Cryo-EM map of C-terminal half of Leucine Rich Repeat Kinase 2 as a WD40-WD40 domain dimer in the presence of the MLi-2 kinase inhibitor at 10.2 angstroms
Method: single particle / : Leschziner A, Deniston C, Lahiri I

PDB-6vno:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

PDB-6vp6:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

PDB-6vp7:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

PDB-6vp8:
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Method: single particle / : Leschziner A, Deniston C, Lahiri I

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