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Showing all 46 items for (author: delaine & c)

EMDB-43648:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic, Original map receptor
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43649:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic, Original map G protein
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43652:
Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI, Original map G protein
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43653:
Kappa opioid receptor:Galphai protein in complex with inverse agonist GB18, Original map receptor
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43654:
Kappa opioid receptor:Galphai protein in complex with inverse agonist GB18, Original map G protein
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43556:
Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43557:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-43558:
Kappa opioid receptor in complex with heterotrimerig Gi protein, bound to inverse agonist GB18
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-46585:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic , no scFv16
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

PDB-8vve:
Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

PDB-8vvf:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

PDB-8vvg:
Kappa opioid receptor in complex with heterotrimerig Gi protein, bound to inverse agonist GB18
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

PDB-9d61:
Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic , no scFv16
Method: single particle / : Gati C, Motiwala Z, Tyson AS, Styrpejko D, Han GW, Khan S, Ramos-Gonzalez N, Shenvi R, Majumdar S

EMDB-26676:
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

EMDB-26677:
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

EMDB-26678:
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

EMDB-27043:
Negative stain electron microscopy single particle reconstruction of monoclonal antibody SP1-77 Fab in complex with SARS-CoV2 2P spike
Method: single particle / : Edwards RJ, Mansouri K

EMDB-27044:
Negative stain electron microscopy single particle reconstruction of monoclonal antibody VHH7-7-53 Fab in complex with SARS-CoV2 2P spike
Method: single particle / : Edwards RJ, Mansouri K

EMDB-27046:
Negative stain electron microscopy single particle reconstruction of monoclonal antibody VHH7-5-82 Fab in complex with SARS-CoV2 2P spike
Method: single particle / : Edwards RJ, Mansouri K

PDB-7upw:
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

PDB-7upx:
Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

PDB-7upy:
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion
Method: single particle / : Zhang J, Luo S, Kreutzberger A, Kirchhausen T, Chen B, Haynes B, Alt F

EMDB-24791:
Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

EMDB-24927:
Leg region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

PDB-7s0q:
Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

PDB-7s8v:
Leg region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor
Method: single particle / : Xu Y, Lawrence MC

EMDB-23949:
The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region
Method: single particle / : Blakely AD, Xiong X

EMDB-23950:
The insulin receptor ectodomain in complex with four venom hybrid insulins - symmetric conformation
Method: single particle / : Blakely AD, Xiong X

EMDB-23951:
The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation
Method: single particle / : Blakely AD, Xiong X

PDB-7mqo:
The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region
Method: single particle / : Blakely AD, Xiong X, Kim JH, Menting J, Schafer IB, Schubert HL, Agrawal R, Gutmann T, Delaine C, Zhang Y, Artik GO, Merriman A, Eckert D, Lawrence MC, Coskun U, Fisher SJ, Forbes BE, Safavi-Hemami H, Hill CP, Chou DHC

PDB-7mqr:
The insulin receptor ectodomain in complex with four venom hybrid insulins - symmetric conformation
Method: single particle / : Blakely AD, Xiong X, Kim JH, Menting J, Schafer IB, Schubert HL, Agrawal R, Gutmann T, Delaine C, Zhang Y, Artik GO, Merriman A, Eckert D, Lawrence MC, Coskun U, Fisher SJ, Forbes BE, Safavi-Hemami H, Hill CP, Chou DHC

PDB-7mqs:
The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation
Method: single particle / : Blakely AD, Xiong X, Kim JH, Menting J, Schafer IB, Schubert HL, Agrawal R, Gutmann T, Delaine C, Zhang Y, Artik GO, Merriman A, Eckert D, Lawrence MC, Coskun U, Fisher SJ, Forbes BE, Safavi-Hemami H, Hill CP, Chou DHC

EMDB-21415:
Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21416:
Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21417:
Head region of the close conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS

EMDB-21418:
Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II
Method: single particle / : Xu Y, Kirk NS

PDB-6vwg:
Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS, Lawrence MC, Croll TI

PDB-6vwh:
Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS, Lawrence MC, Croll TI

PDB-6vwi:
Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.
Method: single particle / : Xu Y, Kirk NS, Lawrence MC, Croll TI

PDB-6vwj:
Leg region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II
Method: single particle / : Xu Y, Kirk NS, Lawrence MC, Croll TI

EMDB-20817:
Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson RC

EMDB-20818:
Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson RC

EMDB-20819:
Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson R, Saunders K, Haynes BF

PDB-6um5:
Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson RC, Saunders KO, Haynes BF

PDB-6um6:
Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson RC, Saunder KO, Haynes BF

PDB-6um7:
Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env
Method: single particle / : Acharya P, Henderson RC, Saunders K, Haynes BF

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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