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Showing all 46 items for (author: cheng & xy)

EMDB-62784:
Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
Method: single particle / : Che T, Zhang J, Xiong B, Cheng XY

EMDB-64801:
Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
Method: single particle / : Che T, Zhang J, Xiong B, Cheng XY

EMDB-61215:
Structureal mechanism of human TRPM3 ion channel inhibition
Method: single particle / : Yang TT, Cheng XY

EMDB-47731:
(Apo)Alpha-synuclein fibril structures from MSA patient brain
Method: helical / : Lu J, Sawaya MR, Ge P, Boyer DR, Eisenberg DS

EMDB-47732:
Complex fibril structure of MSA alpha-synuclein with CNS-11g at 4 hours
Method: helical / : Lu J, Sawaya MR, Ge P, Boyer DR, Eisenberg DS

EMDB-47733:
Complex fibril structure of MSA alpha-synuclein with CNS-11g at 6 hours
Method: helical / : Lu J, Sawaya MR, Ge P, Boyer DR, Eisenberg DS

EMDB-47734:
Complex fibril structure of MSA alpha-synuclein with CNS-11g at 10 hours
Method: helical / : Lu J, Sawaya MR, Ge P, Boyer DR, Eisenberg DS

EMDB-47735:
Complex fibril structure of MSA alpha-synuclein with CNS-11g at 15 hours
Method: helical / : Lu J, Sawaya MR, Ge P, Boyer DR, Eisenberg DS

EMDB-47736:
CNS-11g alone fibril
Method: helical / : Lu J, Sawaya MR

EMDB-63935:
structure of human KCNQ1-KCNE1-CaM complex
Method: single particle / : Hou PP, Zhang J, Wan SY, Cheng XY, Zhong L, Hu B

EMDB-64038:
structure of human KCNQ1-KCNE1-CaM complex with PIP2
Method: single particle / : Hou PP, Zhang J, Wan SY, Cheng XY, Zhong L, Hu B

EMDB-38961:
Structural mechanism of human HCN1 hyperpolarization-activated channel inhibition by ivabradine
Method: single particle / : Che T, Cheng XY

EMDB-62060:
Cryo-EM structure of the human TRPC1/C5 heteromer
Method: single particle / : Chen YX, Cheng XY, Zhang J

EMDB-63417:
IAA-bound AUX1
Method: single particle / : Wang CC, Jing D, Kong F, Huang GXY, Shi YG

EMDB-63418:
IAA-free AUX1
Method: single particle / : Jing D, Kong F, Wang CC, Shi YG, Huang GXY

EMDB-39865:
Cryo-EM structure of human GPR4-Gs complex
Method: single particle / : Chen LN, Mao CY, Cheng SZ, Liu YF, Fu YF, Ma XY, Xu P, Ji SY, Wang WW, Shen DD, Zhang HB, Shen QY, Chai R, Zhang M, Yang L, Han F, Cai XJ, Zhang Y

EMDB-63219:
Cryo-EM structure of human apo inactive GPR4
Method: single particle / : Chen LN, Zhou H, Xi K, Cheng SZ, Liu YF, Fu YF, Ma XY, Xu P, Ji SY, Wang WW, Shen DD, Zhang HB, Shen QY, Chai R, Zhang M, Yang L, Han F, Mao CY, Cai XJ, Zhang Y

EMDB-39866:
Cryo-EM structure of human GPR4-Gi complex
Method: single particle / : Chen LN, Zhou H, Xi K, Cheng SZ, Liu YF, Fu YF, Ma XY, Xu P, Ji SY, Wang WW, Shen DD, Zhang HB, Shen QY, Chai R, Zhang M, Yang L, Han F, Mao CY, Cai XJ, Zhang Y

EMDB-63220:
Cryo-EM structure of antagonist-bounded inactive human GPR4
Method: single particle / : Chen LN, Zhou H, Xi K, Cheng SZ, Liu YF, Fu YF, Ma XY, Xu P, Ji SY, Wang WW, Shen DD, Zhang HB, Shen QY, Chai R, Zhang M, Yang L, Han F, Mao CY, Cai XJ, Zhang Y

EMDB-38801:
Cryo-EM structure of Short-wave-sensitive opsin 1
Method: single particle / : Peng Q, Jiang HH, Cheng XY, Li J, Zhang J

EMDB-62991:
Clostridium botulinum ncRNA homo-dimer
Method: single particle / : Jia XY, Wang L, Su ZM

EMDB-63198:
Post-fusion ectodomain of KSHV gB in complex with 2C4 Fab
Method: single particle / : Fang XY, Sun C, Xie C, Zeng MS, Liu Z

EMDB-38910:
Structure of KSHV glycoprotein B
Method: single particle / : Fang XY, Sun C, Xie C, Liu Z, Zeng MS

EMDB-63209:
Local map of interface of KSHV gB and 2C4 fab
Method: single particle / : Fang XY, Sun C, Xie C, Zeng MS, Liu Z

EMDB-38800:
Cryo-EM structure of Medium-wave-sensitive opsin 1
Method: single particle / : Peng Q, Jiang HH, Cheng XY, Li J, Zhang J

EMDB-38481:
Cryo-EM structure of the Apo CCR8-Gi complex
Method: single particle / : Peng Q, Jiang HH, Cheng XY, Li J, Zhang J

EMDB-36840:
3-Methylcrotonyl-CoA Carboxylase in MCCD state with Acetyl CoA
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-36704:
Human 3-methylcrotonyl-CoA carboxylase in MCCU state with MCoA
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-36705:
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state with MCoA
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-36706:
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state with MCoA
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-35827:
Structure of CbCas9 bound to 20-nucleotide complementary DNA substrate
Method: single particle / : Zhang S, Lin S, Liu JJG

EMDB-37652:
Structure of CbCas9 bound to 6-nucleotide complementary DNA substrate
Method: single particle / : Zhang S, Lin S, Liu JJG

EMDB-37656:
Structure of CbCas9-PcrIIC1 complex bound to 28-bp DNA substrate (20-nt complementary)
Method: single particle / : Zhang S, Lin S, Liu JJG

EMDB-37657:
Structure of CbCas9-PcrIIC1 complex bound to 62-bp DNA substrate (symmetric 20-nt complementary)
Method: single particle / : Zhang S, Lin S, Liu JJG

EMDB-37762:
Structure of CbCas9-PcrIIC1 complex bound to 62-bp DNA substrate (non-targeting complex)
Method: single particle / : Zhang S, Lin S, Liu JJG

EMDB-36128:
Human MCC in MCCU state
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-36136:
Human MCC in MCCD state
Method: single particle / : Liu DS, Su JY, Tian XY

EMDB-35714:
Cryo-EM structure of Long-wave-sensitive opsin 1
Method: single particle / : Peng Q, Cheng XY, Li J, Lu QY, Li YY, Zhang J

EMDB-34948:
Cryo-EM structure of the apo-GPR132-Gi
Method: single particle / : Wang JL, Ding JH, Sun JP, Yu X

EMDB-34950:
Activation mechanism of GPR132 by NPGLY
Method: single particle / : Wang JL, Ding JH, Sun JP, Yu X

EMDB-34951:
Activation mechanism of GPR132 by 9(S)-HODE
Method: single particle / : Wang JL, Ding JH, Sun JP, Yu X

EMDB-35044:
Activation mechanism of GPR132 by compound NOX-6-7
Method: single particle / : Wang JL, Ding JH, Sun JP, Yu X

EMDB-30482:
SARS-CoV-2 spike protein and P17 fab complex with one RBD in close state
Method: single particle / : Wang X, Wang N

EMDB-30483:
Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state
Method: single particle / : Wang N, Wang X

EMDB-30484:
P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein
Method: single particle / : Wang N, Wang X

EMDB-30485:
SARS-CoV-2 spike protein RBD and P17 fab complex
Method: single particle / : Wang X, Wang N

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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