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Showing all 47 items for (author: carpenter & ep)

EMDB-48407:
E. coli GroEL bound with ATP and PBZ1587 inhibitor
Method: single particle / : Johnson SM, Chen Q

EMDB-48408:
E. coli SR1 single-ring GroEL oligomer
Method: single particle / : Johnson SM, Chen Q

EMDB-48409:
E. coli SR1 single-ring GroEL templated into pseudo-double-ring complex with PBZ1587 inhibitor
Method: single particle / : Johnson SM, Chen Q

EMDB-48410:
E. coli SR1 single-ring GroEL oligomer
Method: single particle / : Johnson SM, Chen Q

EMDB-48411:
E. coli GroES-GroEL-GroES football complex
Method: single particle / : Johnson SM, Chen Q

EMDB-51158:
Structure of the human two pore domain potassium ion channel TASK-3 (K2P9.1)
Method: single particle / : Hall PH, Rodstrom KEJ, Tucker SJ

EMDB-51159:
Structure of the human two pore domain potassium ion channel TASK-3 (K2P9.1) G236R mutant
Method: single particle / : Rodstrom KEJ, Hall PH, Tucker SJ

EMDB-51160:
Structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1)
Method: single particle / : Rodstrom KEJ, Hall PH, Tucker SJ

PDB-9g9v:
Structure of the human two pore domain potassium ion channel TASK-3 (K2P9.1)
Method: single particle / : Hall PH, Rodstrom KEJ, Tucker SJ

PDB-9g9w:
Structure of the human two pore domain potassium ion channel TASK-3 (K2P9.1) G236R mutant
Method: single particle / : Rodstrom KEJ, Hall PH, Tucker SJ

PDB-9g9x:
Structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1)
Method: single particle / : Rodstrom KEJ, Hall PH, Tucker SJ

EMDB-18770:
Structure of human ceramide synthase 6 (CerS6) bound to C16:0
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-18771:
Structure of human ceramide synthase 6 (CerS6) in complex with N-palmitoyl fumonisin B1
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-19869:
Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-17377:
Structure of human SIT1 (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17378:
Structure of human SIT1:ACE2 complex (open PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17379:
Structure of human SIT1:ACE2 complex (closed PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17380:
Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17381:
Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17382:
Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-19066:
TREK2 in OGNG/CHS detergent micelle with biparatopic inhibitory nanobody Nb6158
Method: single particle / : Smith KHM, Tucker SJ

EMDB-13036:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 2
Method: single particle / : Grieben M, Pike ACW

EMDB-13037:
Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 1
Method: single particle / : Grieben M, Pike ACW

EMDB-24334:
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
Method: single particle / : Sun B, Kobilka BK

EMDB-24401:
cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

EMDB-24445:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form
Method: single particle / : Sun B, Kobilka BK

EMDB-24453:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7ra3:
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rbt:
cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rg9:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

PDB-7rgp:
cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide
Method: single particle / : Sun B, Kobilka BK, Sloop KW, Feng D, Kobilka TS

EMDB-12566:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B
Method: single particle / : Baronina A, Pike ACW

EMDB-13035:
Cryo-EM structure of human TMEM45A
Method: single particle / : Grieben M, Pike ACW

EMDB-11674:
Cryo-EM structure of the cytoplasmic domain of human TRPC6
Method: single particle / : Grieben M, Pike ACW

EMDB-10094:
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with TFB-TBOA
Method: single particle / : Baronina A, Pike ACW

EMDB-10418:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2
Method: single particle / : Wang Q, Pike ACW

EMDB-10419:
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2
Method: single particle / : Wang Q, Pike ACW

EMDB-9187:
Cryo-EM structure of the human neutral amino acid transporter ASCT2
Method: single particle / : Yu X, Han S

EMDB-9188:
Cryo-EM structure of the human neutral amino acid transporter ASCT2
Method: single particle / : Yu X, Han S

EMDB-0093:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Method: single particle / : Shintre CA, Pike ACW

EMDB-4746:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR

EMDB-4747:
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form)
Method: single particle / : Pike ACW, Bushell SR

EMDB-4748:
CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form)
Method: single particle / : Pike ACW, Bushell SR

EMDB-0094:
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Method: single particle / : Shintre CA, Pike ACW

EMDB-3523:
cryoEM Structure of Polycystin-2 in complex with cations and lipids
Method: single particle / : Wilkes M, Madej MG

EMDB-3524:
cryoEM Structure of Polycystin-2 in complex with calcium and lipids
Method: single particle / : Wilkes M, Madej MG

EMDB-8200:
CryoEM structure of a human TRP channel
Method: single particle / : Pike ACW, Grieben M

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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