EMDB-54307:
VPS34-CI bound to NRBF2 and RAB1A, focused refinement on the kinase arm
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54308:
VPS34-CI bound to NRBF2 and RAB1A, focused refinement on the adaptor arm
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54309:
VPS34-CI bound to NRBF2 and RAB1A, focused refinement on the interface between RAB1A and VPS34
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54310:
VPS34-CI bound to NRBF2 and RAB1A, consensus refinement
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54311:
VPS34-CI bound to NRBF2 and RAB1A; composite unsharpened map
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54323:
VPS34-CI bound to NRBF2 MIT domain (residues 1-79), focused refinement on the VPS34 kinase domain and VPS15 pseudokinase domain
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54324:
VPS34-CI bound to NRBF2 MIT domain (residues 1-79), focused refinement on the VPS15 WD40 domain, BECLIN1 BARA domain, and ATG14L CTD
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54325:
VPS34-CI bound to NRBF2 MIT domain (residues 1-79, focused refinement on the VPS15 helical solenoid, and ATG14L/BECLIN1 CC1 and N-terminal domains
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54326:
VPS34-CI bound to NRBF2 MIT domain (residues 1-79), consensus refinement
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54357:
VPS34-CI bound to NRBF2 and RAB1A, primary composite map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54360:
VPS34-CI bound to NRBF2 MIT domain (residues 1-79), unsharpened composite EM map
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rx4: 構造ビューア
VPS34-CI bound to NRBF2 and RAB1A
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rx7: 構造ビューア
VPS34-CI bound to NRBF2 MIT domain (residues 1-79)
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54312:
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L, focused refinement on the adaptor arm)
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54313:
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L, focused refinement on the kinase arm)
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54314:
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L), focused refinement on the base of the complex
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54315:
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L, focused refinement on the interface between RAB5A and VPS34)
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54316:
VPS34-CII (VPS34 199-REIE-202 > 199-AAAA-202 mutant) bound to RAB5A-GTP (Q79L), consensus refinement
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54317:
VPS34-CII (VPS34 199-REIE-202 > 199-AAAA-202 mutant) bound to RAB5A-GTP (Q79L); unsharpened composite map
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54318:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit, focused refinement on the kinase arm
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54319:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit, focused refinement on the adaptor arm
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54320:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit, focused refinement of the RAB5A interface with VPS15
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54321:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit, consensus refinement
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54322:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit; unsharpened composite map
手法: 単粒子 / : Spokaite S, Ohashi Y, Bourguet M, Dessus AN, Williams RL

EMDB-54358:
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L), primary composite map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54359:
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit, composite map processed with CryoTEN.
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54361:
Apo VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG), consensus refinement map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54362:
VPS34-CII bound to RAB5A-GTP 1-212 (C19S, C63S, Q79L) on the VPS34 subunit, primary map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54363:
VPS34-CII bound to RAB5A-GTP 1-212 (C19S, C63S, Q79L) on the VPS15 subunit, primary map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54364:
VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG) bound to RAB5A (Q79L) on the VPS34 and VPS15 subunits, primary map processed with CryoTEN
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

EMDB-54560:
Human complex II-BATS bound to membrane-attached Rab5a-GTP
手法: サブトモグラム平均 / : Dessus AN, Tremel S, Williams RL

PDB-9rx5: 構造ビューア
VPS34-CII (VPS34 199-REIE-202 to 199-AAAA-202 mutant) bound to RAB5A (Q79L)
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rx6: 構造ビューア
VPS34-CII (VPS34 199-REIE-202 to 199-ERIR-202 mutant) bound to RAB5A (Q79L) on the VPS15 subunit
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rx8: 構造ビューア
Apo VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG)
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rx9: 構造ビューア
VPS34-CII bound to RAB5A-GTP 1-212 (C19S, C63S, Q79L) on the VPS34 subunit
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rxa: 構造ビューア
VPS34-CII bound to RAB5A-GTP 1-212 (C19S, C63S, Q79L) on the VPS15 subunit
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9rxb: 構造ビューア
VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG) bound to RAB5A (Q79L) on the VPS34 and VPS15 subunits
手法: 単粒子 / : Spokaite S, Ohashi Y, Dessus AN, Bourguet M, Williams RL

PDB-9s47: 構造ビューア
Human complex II-BATS bound to membrane-attached Rab5a-GTP
手法: サブトモグラム平均 / : Dessus AN, Tremel S, Williams RL

EMDB-55637:
cryo-EM structure of AKT phosphorylated mTOR complex 2, overall refinement
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-55714:
cryo-EM structure of autophosphorylated mTOR complex 2, overall refinement
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-55715:
cryo-EM structure of autophosphorylated mTOR complex 2, focused on a single protomer
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-55716:
cryo-EM structure of AKT phosphorylated mTOR complex 2, focused on a single protomer
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-55803:
cryo-EM structure of dephosphorylated mTOR complex 2, overall refinement
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-55804:
cryo-EM structure of dephosphorylated mTOR complex 2, focused on a single protomer
手法: 単粒子 / : Hay IM, Anandapadamanaban M, Williams RL

EMDB-56117:
cryo-ET structure of mTOR complex 2 on a PIP2-containing membrane
手法: サブトモグラム平均 / : Hay IM, Ahsan B, Williams RL

EMDB-18498:
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
手法: 単粒子 / : Kwong HS, Grandvuillemin L, Sirounian S, Ancelin A, Lai-Kee-Him J, Carivenc C, Lancey C, Ragan TJ, Hesketh EL, Bourguet W, Gruszczyk J

PDB-8qmo: 構造ビューア
Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex
手法: 単粒子 / : Kwong HS, Grandvuillemin L, Sirounian S, Ancelin A, Lai-Kee-Him J, Carivenc C, Lancey C, Ragan TJ, Hesketh EL, Bourguet W, Gruszczyk J

EMDB-14971:
Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex
手法: 単粒子 / : Gruszczyk J, Savva CG, Lai-Kee-Him J, Bous J, Ancelin A, Kwong HS, Grandvuillemin L, Bourguet W

EMDB-14972:
Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex (focused map).
手法: 単粒子 / : Gruszczyk J, Savva CG, Lai-Kee-Him J, Bous J, Ancelin A, Kwong HS, Grandvuillemin L, Bourguet W

PDB-7zub: 構造ビューア
Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex
手法: 単粒子 / : Gruszczyk J, Savva CG, Lai-Kee-Him J, Bous J, Ancelin A, Kwong HS, Grandvuillemin L, Bourguet W