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Showing 1 - 50 of 212 items for (author: aricescu & r)

EMDB-54547:
Cerebellar GluA1/4 NTD tetramer (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

PDB-9s3q:
Cerebellar GluA1/4 NTD tetramer (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-54556:
Cerebellar GluA1/4 LBD tetramer (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

PDB-9s3z:
Cerebellar GluA1/4 LBD tetramer (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-54543:
Cerebellar GluA2/4 NTD heterophilic tetramer interface (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-54558:
Cerebellar GluA1/4 TMD with TARP gamma 7 (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-54559:
Cerebellar GluAx/A4 TMD with four TARPs (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-55413:
GluA4 N-terminal domain bound to nanobody NB74 (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-55414:
GluA4 LBD-TMD with TARP gamma 2 (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-55418:
GluA4 with TARP gamma2 (consensus refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-55419:
Full-length GluA4 with TARP gamma 2 (composite map)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

PDB-9s3o:
Cerebellar GluA2/4 NTD heterophilic tetramer interface (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

PDB-9s41:
Cerebellar GluA1/4 TMD with TARP gamma 7 (focused refinement)
Method: single particle / : Sengupta N, Scrutton A, Greger IH, Krieger JM

EMDB-50974:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived desensitised state (C5) sprayed with PBS
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

PDB-9g2e:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived desensitised state (C5) sprayed with PBS
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

EMDB-50973:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state (C5) sprayed with PBS
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

PDB-9g2d:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state (C5) sprayed with PBS
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

EMDB-50276:
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from desensitised state obtained by focused refinement
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fan:
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from desensitised state obtained by focused refinement
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50277:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC1)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fap:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC1)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50274:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fak:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50284:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, HEPES and Megabody25, in a desensitised state
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9faw:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, HEPES and Megabody25, in a desensitised state
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50275:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD3)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fam:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD3)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50279:
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from a closed state, obtained by focused refinement
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9far:
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from a closed state, obtained by focused refinement
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50278:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC2)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9faq:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 and Megabody38 in a closed state (StateC2)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50273:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9faj:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38, in a desensitised state (StateD1)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50281:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, Megabody38 and pregnenolone sulfate
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fat:
CryoEM structure of human full-length alpha1beta3gamma2 GABA(A)R in complex with GARLH4, the TMD of Neuroligin2, Megabody38 and pregnenolone sulfate
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-17636:
Cryo-EM structure of the full-length human alpha1beta3 GABA(A) receptor (babba arrangement) in complex with nanobody Nb25, expressed with a 5-fold excess of beta3 over alpha1
Method: single particle / : Sente A, Malinauskas T, Naydenova K, Hardwick SW, Chirgadze DY, Aricescu AR

PDB-8pet:
Cryo-EM structure of the full-length human alpha1beta3 GABA(A) receptor (babba arrangement) in complex with nanobody Nb25, expressed with a 5-fold excess of beta3 over alpha1
Method: single particle / : Sente A, Malinauskas T, Naydenova K, Hardwick SW, Chirgadze DY, Aricescu AR

EMDB-50285:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with Megabody25, doubly occupied GARLH4 and Neuroligin2 TMD, in a closed state
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fax:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with Megabody25, doubly occupied GARLH4 and Neuroligin2 TMD, in a closed state
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50282:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fau:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50283:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC2)
Method: single particle / : Kasaragod VB, Aricescu AR

PDB-9fav:
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC2)
Method: single particle / : Kasaragod VB, Aricescu AR

EMDB-50347:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric open state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

PDB-9ff0:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in complex with HSM in the short-lived asymmetric open state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

EMDB-50380:
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric open 2 state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

PDB-9fg0:
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric open 2 state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

EMDB-50342:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

PDB-9fev:
Cryo-EM structure of the beta3 homomeric GABA(A) receptor in the long-lived resting state
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

EMDB-50371:
Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric bound-closed state of branch 2
Method: single particle / : Mihaylov DB, Malinauskas T, Aricescu AR

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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