Author results

3M99
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STRUCTURE OF THE UBP8-SGF11-SGF73-SUS1 SAGA DUB MODULE
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8, SAGA-associated factor 11, Protein SUS1, ...
Authors:Kohler, A., Zimmerman, E., Schneider, M., Hurt, E., Zheng, N.
Deposit date:2010-03-21
Release date:2010-05-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module.
Cell(Cambridge,Mass.), 141, 2010
3JCS
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2.8 ANGSTROM CRYO-EM STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM THE EUKARYOTIC PARASITE LEISHMANIA
Descriptor:26S alpha ribosomal RNA, 26S delta ribosomal RNA, 26S gamma ribosomal RNA, ...
Authors:Shalev-Benami, M., Zhang, Y., Matzov, D., Halfon, Y., Zackay, A., Rozenberg, H., Zimmerman, E., Bashan, A., Jaffe, C.L., Yonath, A., Skiniotis, G.
Deposit date:2016-01-21
Release date:2016-07-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Cell Rep, 16, 2016
3PIO
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CRYSTAL STRUCTURE OF THE SYNERGISTIC ANTIBIOTIC PAIR LANKAMYCIN AND LANKACIDIN IN COMPLEX WITH THE LARGE RIBOSOMAL SUBUNIT
Descriptor:RIBOSOMAL 23S RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Belousoff, M.J., Shapira, T., Bashan, A., Zimmerman, E., Arakawa, K., Kinashi, H., Rozenberg, H., Yonath, A.
Deposit date:2010-11-07
Release date:2011-02-23
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (3.2473 Å)
Cite:Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 108, 2011
3PIP
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CRYSTAL STRUCTURE OF THE SYNERGISTIC ANTIBIOTIC PAIR LANKAMYCIN AND LANKACIDIN IN COMPLEX WITH THE LARGE RIBOSOMAL SUBUNIT
Descriptor:RIBOSOMAL 23S RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Belousoff, M.J., Shapira, T., Bashan, A., Zimmerman, E., Kinashi, H., Rozenberg, H., Yonath, A.
Deposit date:2010-11-07
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
Proc.Natl.Acad.Sci.USA, 108, 2011
4U67
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CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS CONTAINING A THREE RESIDUE INSERTION IN L22
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.
Deposit date:2014-07-28
Release date:2015-08-05
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
4WCE
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.
Deposit date:2014-09-04
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.526 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WF9
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH TELITHROMYCIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (3.427 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFA
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINEZOLID
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.392 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFB
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH BC-3205
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.E.
Deposit date:2014-09-14
Release date:2015-10-21
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WFN
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CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS CONTAINING A THREE RESIDUE INSERTION IN L22 IN COMPLEX WITH ERYTHROMYCIN
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Wekselman, I., Zimmerman, E., Rozenberg, H., Bashan, A., Yonath, A.
Deposit date:2014-09-16
Release date:2015-12-23
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
5HKV
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINCOMYCIN
Descriptor:23s ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2016-01-14
Release date:2017-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5HL7
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LEFAMULIN
Descriptor:50S ribosomal protein L2, 23S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Eyal, Z., Matzov, D., Krupkin, M., Rozenberg, H., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2016-01-14
Release date:2016-12-21
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
5JVG
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THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH AVILAMYCIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Krupkin, M., Wekselman, I., Matzov, D., Eyal, Z., Diskin Posner, Y., Rozenberg, H., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5NGM
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2.9S STRUCTURE OF THE 70S RIBOSOME COMPOSING THE S. AUREUS 100S COMPLEX
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Matzov, D., Aibara, S., Zimmerman, E., Bashan, A., Amunts, A., Yonath, A.
Deposit date:2017-03-18
Release date:2017-10-04
Last modified:2018-11-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
5NRG
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH RB02
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2017-04-23
Release date:2017-08-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.442 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5TCU
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METHICILLIN SENSITIVE STAPHYLOCOCCUS AUREUS 70S RIBOSOME
Descriptor:16S RRNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Eyal, Z., Ahmed, T., Belousoff, N., Mishra, S., Matzov, D., Bashan, A., Zimmerman, E., Lithgow, T., Bhushan, S., Yonath, A.
Deposit date:2016-09-15
Release date:2017-05-24
Last modified:2017-09-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
6AZ1
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CRYO-EM STRUCTURE OF THE SMALL SUBUNIT OF LEISHMANIA RIBOSOME BOUND TO PAROMOMYCIN
Descriptor:Ribosomal protein s1e, ribosomal protein S2, ribosomal protein S3, ...
Authors:Shalev-Benami, M., Zhang, Y., Rozenberg, H., Matzov, D., Zimmerman, E., Bashan, A., Jaffe, C.L., Yonath, A., Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
6AZ3
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CRYO-EM STRUCTURE OF OF THE LARGE SUBUNIT OF LEISHMANIA RIBOSOME BOUND TO PAROMOMYCIN
Descriptor:ribosomal protein uL2, ribosomal protein uL3, ribosomal protein uL4, ...
Authors:Shalev-Benami, M., Zhang, Y., Rozenberg, H., Nobe, Y., Taoka, M., Matzov, D., Zimmerman, E., Bashan, A., Isobe, T., Jaffe, C.L., Yonath, A., Skiniotis, G.
Deposit date:2017-09-09
Release date:2017-12-06
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin.
Nat Commun, 8, 2017
6FXC
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THE CRYO-EM STRUCTURE OF HIBERNATING 100S RIBOSOME DIMER FROM PATHOGENIC STAPHYLOCOCCUS AUREUS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Matzov, D., Aibara, S., Zimmerman, E., Bashan, A., Kidmose, R., Amunts, A., Yonath, A.
Deposit date:2018-03-08
Release date:2018-03-21
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (6.76 Å)
Cite:The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Nat Commun, 8, 2017
3JQ4
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THE STRUCTURE OF THE COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM D. RADIODURANS WITH THE ANTIBIOTIC LANKACIDIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide
Authors:Auerbach-Nevo, T., Mermershtain, I., Davidovich, C., Bashan, A., Rozenberg, H., Yonath, A.
Deposit date:2009-09-06
Release date:2010-09-08
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
Proc.Natl.Acad.Sci.USA, 107, 2010
5JVH
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THE CRYSTAL STRUCTURE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS IN COMPLEX WITH EVERNIMICIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T7V
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METHICILLIN RESISTANT, LINEZOLID RESISTANT STAPHYLOCOCCUS AUREUS 70S RIBOSOME (DELTA S145 UL3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Belousoff, M.J., Lithgow, T., Eyal, Z., Yonath, A., Radjainia, M.
Deposit date:2016-09-06
Release date:2017-05-31
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8, 2017
6HMA
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IMPROVED MODEL DERIVED FROM CRYO-EM MAP OF STAPHYLOCOCCUS AUREUS LARGE RIBOSOMAL SUBUNIT
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Eyal, Z., Cimicata, G., Matzov, D., Fox, T., de Val, N., Zimmerman, E., Bashan, A., Yonath, A.
Deposit date:2018-09-12
Release date:2018-11-14
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit
To Be Published