Author results

3J6Q
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IDENTIFICATION OF THE ACTIVE SITES IN THE METHYLTRANSFERASES OF A TRANSCRIBING DSRNA VIRUS
分子名称:Structural protein VP3, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhu, B., Yang, C., Liu, H., Cheng, L., Song, F., Zeng, S., Huang, X., Ji, G., Zhu, P.
登録日2014-03-20
公開日2014-10-08
最終更新日2014-10-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Identification of the active sites in the methyltransferases of a transcribing dsRNA virus.
J.Mol.Biol., 426, 2014
5SYB
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CRYSTAL STRUCTURE OF HUMAN PHF5A
分子名称:PHD finger-like domain-containing protein 5A, ZINC ION, 1,2-ETHANEDIOL
著者Tsai, J.H.C., Teng, T., Zhu, P., Fekkes, P., Larsen, N.A.
登録日2016-08-10
公開日2016-09-07
最終更新日2017-06-07
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Nat Commun, 8, 2017
5X0T
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CRYSTAL STRUCTURE OF CD147 C2 DOMAIN IN COMPLEX WITH FAB OF ITS MONOCLONAL ANTIBODY 6H8
分子名称:6H8 Fab fragment heavy chain, 6H8 Fab fragment light chain, Basigin
著者Lin, P., Zhang, M.-Y., Ye, S., Chen, X., Yu, X.-L., Zhang, R.-G., Zhu, P., Chen, Z.-N.
登録日2017-01-23
公開日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
To Be Published
5X4G
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CRYSTAL STRUCTURE OF FAB FRAGMENT OF ANTI-CD147 MONOCLONAL ANTIBODY 6H8
分子名称:6H8 Fab heavy chain, 6H8 Fab light chain
著者Lin, P., Zhang, M.-Y., Chen, X., Ye, S., Yu, X.-L., Zhang, R.-G., Zhu, P., Chen, Z.-N.
登録日2017-02-13
公開日2018-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody
To Be Published
2IJ0
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STRUCTURAL BASIS OF T CELL SPECIFICITY AND ACTIVATION BY THE BACTERIAL SUPERANTIGEN TOXIC SHOCK SYNDROME TOXIN-1
分子名称:Toxic shock syndrome toxin-1, penultimate affinity-matured variant of hVbeta 2.1, D10
著者Moza, B., Varma, A.K., Buonpane, R.A., Zhu, P., Herfst, C.A., Nicholson, M.J., Wilbuer, A.K., Nulifer, S., Wucherpfenning, K.W., McCormick, J.K., Kranz, D.M., Sundberg, E.J.
登録日2006-09-28
公開日2007-02-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1.
Embo J., 26, 2007
3IZ3
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CRYOEM STRUCTURE OF CYTOPLASMIC POLYHEDROSIS VIRUS
分子名称:Structural protein VP3, Structural protein VP1, Viral structural protein 5
著者Cheng, L., Sun, J., Zhang, K., Mou, Z., Huang, X., Ji, G., Sun, F., Zhang, J., Zhu, P.
登録日2010-09-14
公開日2011-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping.
Proc.Natl.Acad.Sci.USA, 108, 2011
3J17
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STRUCTURE OF A TRANSCRIBING CYPOVIRUS BY CRYO-ELECTRON MICROSCOPY
分子名称:Structural protein VP3, VP1, Structural protein VP5
著者Yang, C., Ji, G., Liu, H., Zhang, K., Liu, G., Sun, F., Zhu, P., Cheng, L.
登録日2011-12-25
公開日2012-04-04
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of a transcribing cypovirus.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZIF
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CRYO-EM STRUCTURES OF TWO INTERMEDIATES PROVIDE INSIGHT INTO ADENOVIRUS ASSEMBLY AND DISASSEMBLY
分子名称:HEXON PROTEIN, PENTON PROTEIN, PIX, ...
著者Cheng, L., Huang, X., Li, X., Xiong, W., Sun, W., Yang, C., Zhang, K., Wang, Y., Liu, H., Ji, G., Sun, F., Zheng, C., Zhu, P.
登録日2013-01-09
公開日2014-01-22
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
4J1G
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSRNA COMPLEX
分子名称:Nucleocapsid, RNA (45-MER)
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2013-06-12
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J1J
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LEANYER ORTHOBUNYAVIRUS NUCLEOPROTEIN-SSDNA COMPLEX
分子名称:Nucleocapsid, DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3')
著者Niu, F., Shaw, N., Wang, Y., Jiao, L., Ding, W., Li, X., Zhu, P., Upur, H., Ouyang, S., Cheng, G., Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2014-11-05
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6O8A
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THAUMATIN NATIVE-SAD STRUCTURE DETERMINED AT 5 KEV FROM MICROCRYSTALS
分子名称:Thaumatin-1, L(+)-TARTARIC ACID
著者Guo, G., Zhu, P., Fuchs, M.R., Shi, W., Andi, B., Gao, Y., Hendrickson, W.A., McSweeney, S., Liu, Q.
登録日2019-03-09
公開日2019-05-08
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synchrotron microcrystal native-SAD phasing at a low energy.
Iucrj, 6, 2019
5ZBF
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CRYSTAL STRUCTURE OF 4-HYDROXYPHENYLPYRUVIC ACID BOUND AERE FROM MICROCYSTIS AERUGINOSA
分子名称:Cupin domain protein, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, FE (II) ION
著者Qiu, X., Zhu, W.
登録日2018-02-11
公開日2019-02-13
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional insights into the role of a cupin superfamily isomerase in the biosynthesis of Choi moiety of aeruginosin.
J. Struct. Biol., 205, 2019
2MKZ
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SOLUTION STRUCTURE OF A PROTEIN C-TERMINAL DOMAIN
分子名称:Proteasomal ubiquitin receptor ADRM1
著者Feng, Y., Jiao, L.
登録日2014-02-17
公開日2014-12-31
実験手法SOLUTION NMR
主引用文献Mechanism of the Rpn13-induced activation of Uch37
Protein Cell, 5, 2014
5ZBE
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CRYSTAL STRUCTURE OF AERE FROM MICROCYSTIS AERUGINOSA
分子名称:Cupin domain protein, FE (II) ION, TRIETHYLENE GLYCOL
著者Qiu, X.
登録日2018-02-11
公開日2019-02-13
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional insights into the role of a cupin superfamily isomerase in the biosynthesis of Choi moiety of aeruginosin.
J. Struct. Biol., 205, 2019
5ZWX
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CRYSTAL STRUCTURE OF RAPHANUS SATIVUS AGDP1 AGD12 IN COMPLEX WITH AN H3K9ME2 PEPTIDE
分子名称:DUF724 domain-containing protein 6-like, H3(1-15)K9me2 peptide
著者Du, X., Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018
5ZWZ
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA AGDP1 AGD34
分子名称:Agenet domain-containing protein
著者Du, X., Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018
5VND
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CRYSTAL STRUCTURE OF FGFR1-Y563C (FGFR4 SURROGATE) COVALENTLY BOUND TO H3B-6527
分子名称:Fibroblast growth factor receptor 1, N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide, SULFATE ION, ...
著者Tsai, J.H.C., Reynolds, D., Fekkes, P., Smith, P., Larsen, N.A.
登録日2017-04-30
公開日2017-05-24
最終更新日2018-12-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Cancer Res., 77, 2017
5EHR
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NON-RECEPTOR PROTEIN TYROSINE PHOSPHATASE SHP2 IN COMPLEX WITH ALLOSTERIC INHIBITOR SHP099
分子名称:Tyrosine-protein phosphatase non-receptor type 11, 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, PHOSPHATE ION
著者Stams, T., Fodor, M.
登録日2015-10-28
公開日2016-06-29
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Nature, 535, 2016
5J9Q
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CRYSTAL STRUCTURE OF THE NUA4 CORE COMPLEX
分子名称:Histone acetyltransferase ESA1, Chromatin modification-related protein EAF6, Enhancer of polycomb-like protein 1, ...
著者Chen, Z.C., Xu, P.
登録日2016-04-11
公開日2016-10-26
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
5J9T
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CRYSTAL STRUCTURE OF THE NUA4 CORE COMPLEX
分子名称:Histone acetyltransferase ESA1, Chromatin modification-related protein EAF6, Enhancer of polycomb-like protein 1, ...
著者Chen, Z.C., Xu, P.
登録日2016-04-11
公開日2016-10-26
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
5J9U
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CRYSTAL STRUCTURE OF THE NUA4 CORE COMPLEX
分子名称:Histone acetyltransferase ESA1, Chromatin modification-related protein EAF6, Enhancer of polycomb-like protein 1, ...
著者Chen, Z.C., Xu, P.
登録日2016-04-11
公開日2016-10-26
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
5J9W
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CRYSTAL STRUCTURE OF THE NUA4 CORE COMPLEX
分子名称:Histone acetyltransferase ESA1, Chromatin modification-related protein EAF6, Enhancer of polycomb-like protein 1, ...
著者Chen, Z.C., Xu, P.
登録日2016-04-11
公開日2016-10-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The NuA4 Core Complex Acetylates Nucleosomal Histone H4 through a Double Recognition Mechanism
Mol.Cell, 63, 2016
6CHW
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ESTROGEN RECEPTOR ALPHA Y537S COVALENTLY BOUND TO ANTAGONIST H3B-5942.
分子名称:Estrogen receptor, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, 1,2-ETHANEDIOL, ...
著者Larsen, N.A.
登録日2018-02-23
公開日2018-03-21
最終更新日2018-09-12
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer.
Cancer Discov, 8, 2018
6CHZ
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ESTROGEN RECEPTOR ALPHA Y537S BOUND TO ANTAGONIST H3B-9224.
分子名称:Estrogen receptor, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, 1,2-ETHANEDIOL
著者Larsen, N.A.
登録日2018-02-23
公開日2018-03-21
最終更新日2018-09-12
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer.
Cancer Discov, 8, 2018
4GA7
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CRYSTAL STRUCTURE OF HUMAN SERPINB1 MUTANT
分子名称:Leukocyte elastase inhibitor
著者Wang, L., Li, Q., Wu, L., Zhang, K., Tong, L., Sun, F., Fan, Z.
登録日2012-07-25
公開日2013-01-16
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of SERPINB1 as a physiological inhibitor of human granzyme H
J.Immunol., 190, 2013
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