5Z9Y | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THIAZOLE SYNTHASE (THIG) COMPLEXED WITH DXP | | Descriptor: | Thiazole synthase, 1-DEOXY-D-XYLULOSE-5-PHOSPHATE | | Authors: | Zhang, J., Zhang, B., Zhao, Y., Yang, X., Huang, M., Cui, P., Zhang, W., Li, J., Zhang, Y. | | Deposit date: | 2018-02-05 | | Release date: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
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4PXZ | | CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESADP | | Descriptor: | P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), ... | | Authors: | Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR) | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-30 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
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4PY0 | | CRYSTAL STRUCTURE OF P2Y12 RECEPTOR IN COMPLEX WITH 2MESATP | | Descriptor: | P2Y purinoceptor 12, Soluble cytochrome b562, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ... | | Authors: | Zhang, J., Zhang, K., Gao, Z.G., Paoletta, S., Zhang, D., Han, G.W., Li, T., Ma, L., Zhang, W., Muller, C.E., Yang, H., Jiang, H., Cherezov, V., Katritch, V., Jacobson, K.A., Stevens, R.C., Wu, B., Zhao, Q., GPCR Network (GPCR) | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-30 | | Last modified: | 2017-08-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Agonist-bound structure of the human P2Y12 receptor
Nature, 509, 2014
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5D6P | | CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND | | Descriptor: | DNA gyrase subunit B, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, (4S)-2-METHYL-2,4-PENTANEDIOL, ... | | Authors: | Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C. | | Deposit date: | 2015-08-12 | | Release date: | 2015-11-25 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
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5D6Q | | CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND | | Descriptor: | DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-{4-[(E)-2-(pyridin-3-yl)ethenyl]-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl}urea, ... | | Authors: | Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C. | | Deposit date: | 2015-08-12 | | Release date: | 2015-11-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
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5D7C | | CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND | | Descriptor: | DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[1-(pyridin-2-yl)-6-(pyridin-3-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl]urea, ... | | Authors: | Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C. | | Deposit date: | 2015-08-13 | | Release date: | 2015-11-25 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
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4G3H | | CRYSTAL STRUCTURE OF HELICOBACTER PYLORI ARGINASE | | Descriptor: | Arginase (RocF), MANGANESE (II) ION | | Authors: | Zhang, J., Zhang, X., Li, D., Hu, Y., Zou, Q., Wang, D. | | Deposit date: | 2012-07-13 | | Release date: | 2012-08-01 | | Last modified: | 2014-12-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and function studies on Helicobacter pylori arginase
To be Published
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1A4F | | BAR-HEADED GOOSE HEMOGLOBIN (OXY FORM) | | Descriptor: | HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Zhang, J., Gu, X. | | Deposit date: | 1998-01-29 | | Release date: | 1998-04-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).
J.Mol.Biol., 255, 1996
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3J03 | | LIDLESS MM-CPN IN THE CLOSED STATE WITH ATP/ALFX | | Descriptor: | Lidless Mm-cpn | | Authors: | Zhang, J., Ma, B., DiMaio, F., Douglas, N.R., Joachimiak, L., Baker, D., Frydman, J., Levitt, M., Chiu, W. | | Deposit date: | 2011-02-10 | | Release date: | 2011-05-18 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
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5ZXL | | STRUCTURE OF GLDA FROM E.COLI | | Descriptor: | Glycerol dehydrogenase, ZINC ION, GLYCEROL, ... | | Authors: | Zhang, J., Lin, L. | | Deposit date: | 2018-05-21 | | Release date: | 2019-03-20 | | Method: | X-RAY DIFFRACTION (2.794 Å) | | Cite: | Structure of glycerol dehydrogenase (GldA) from Escherichia coli.
Acta Crystallogr F Struct Biol Commun, 75, 2019
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4G42 | | STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO PEPITDE P8D | | Descriptor: | MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P8D | | Authors: | Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F. | | Deposit date: | 2012-07-16 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (2.294 Å) | | Cite: | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
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4G43 | | STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 COMPLEXED TO P5E | | Descriptor: | MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE P5E, ... | | Authors: | Zhang, J., Chen, Y., Qi, J., Gao, F., Liu, J., Kaufman, J., Xia, C., Gao, G.F. | | Deposit date: | 2012-07-16 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (1.803 Å) | | Cite: | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
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4TZP | | AS GROWN, UNTREATED CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN | | Descriptor: | Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I | | Authors: | Zhang, J., Ferre-D'Amare, A.R. | | Deposit date: | 2014-07-10 | | Release date: | 2014-09-10 | | Last modified: | 2014-09-24 | | Method: | X-RAY DIFFRACTION (8.503 Å) | | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
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4TZV | | CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN, TREATED BY REMOVING LITHIUM SULFATE POST CRYSTALLIZATION | | Descriptor: | Ribosome-associated protein L7Ae-like, engineered tRNA, T-box stem I | | Authors: | Zhang, J., Ferre-D'Amare, A.R. | | Deposit date: | 2014-07-11 | | Release date: | 2014-09-10 | | Last modified: | 2014-09-24 | | Method: | X-RAY DIFFRACTION (5.03 Å) | | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
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4TZW | | CO-CRYSTALS OF THE TERNARY COMPLEX CONTAINING A T-BOX STEM I RNA, ITS COGNATE TRNAGLY, AND B. SUBTILIS YBXF PROTEIN, TREATED BY REMOVING LITHIUM SULFATE AND REPLACING MG2+ WITH SR2+ POST CRYSTALLIZATION | | Descriptor: | Ribosome-associated protein L7Ae-like, engineered tRNA, T-box Stem I, ... | | Authors: | Zhang, J., Ferre-D'Amare, A.R. | | Deposit date: | 2014-07-11 | | Release date: | 2014-09-10 | | Last modified: | 2014-09-24 | | Method: | X-RAY DIFFRACTION (4.671 Å) | | Cite: | Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
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2M8V | | SOLUTION STRUCTURE AND ACTIVITY STUDY OF BOVICIN HJ50, A PARTICULAR TYPE AII LANTIBIOTIC | | Descriptor: | BovA | | Authors: | Zhang, J., Feng, Y., Wang, J., Zhong, J. | | Deposit date: | 2013-05-29 | | Release date: | 2014-05-21 | | Method: | SOLUTION NMR | | Cite: | Type AII Lantibiotic Bovicin HJ50 with a Rare Disulfide Bond: Structure, Structure-Activity Relationships and Mode of Action
Biochem.J., 2014
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2NWM | |
3IYF | | ATOMIC MODEL OF THE LIDLESS MM-CPN IN THE OPEN STATE | | Descriptor: | Chaperonin | | Authors: | Zhang, J., Baker, M.L., Schroeder, G., Douglas, N.R., Reissmann, S., Jakana, J., Dougherty, M., Fu, C.J., Levitt, M., Ludtke, S.J., Frydman, J., Chiu, W. | | Deposit date: | 2009-10-23 | | Release date: | 2010-02-02 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
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3J02 | | LIDLESS D386A MM-CPN IN THE PRE-HYDROLYSIS ATP-BOUND STATE | | Descriptor: | Lidless D386A Mm-cpn variant | | Authors: | Zhang, J., Ma, B., DiMaio, F., Douglas, N.R., Joachimiak, L., Baker, D., Frydman, J., Levitt, M., Chiu, W. | | Deposit date: | 2011-02-10 | | Release date: | 2011-05-18 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
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3LOS | | ATOMIC MODEL OF MM-CPN IN THE CLOSED STATE | | Descriptor: | Chaperonin | | Authors: | Zhang, J., Baker, M.L., Schroeder, G., Douglas, N.R., Reissmann, S., Jakana, J., Dougherty, M., Fu, C.J., Levitt, M., Ludtke, S.J., Frydman, J., Chiu, W. | | Deposit date: | 2010-02-04 | | Release date: | 2010-03-16 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Mechanism of folding chamber closure in a group II chaperonin
Nature, 463, 2010
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3UIT | | OVERALL STRUCTURE OF PATJ/PALS1/MALS COMPLEX | | Descriptor: | InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B, ... | | Authors: | Zhang, J., Yang, X., Long, J., Shen, Y. | | Deposit date: | 2011-11-06 | | Release date: | 2012-02-22 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode
J.Biol.Chem., 287, 2012
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4E0R | | STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 | | Descriptor: | MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE (FUS/TLS) | | Authors: | Zhang, J., Chen, Y., Qi, J., Gao, F., Kaufman, J., Xia, C., Gao, G.F. | | Deposit date: | 2012-03-05 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
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5D7D | | CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND | | Descriptor: | DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | | Authors: | Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C. | | Deposit date: | 2015-08-13 | | Release date: | 2015-11-11 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
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5D7R | | CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF S. AUREUS GYRB COMPLEXED WITH A LIGAND | | Descriptor: | DNA gyrase subunit B, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Zhang, J., Yang, Q., Cross, J.B., Romero, J.A.C., Ryan, M.D., Lippa, B., Dolle, R.E., Andersen, O.A., Barker, J., Cheng, R.K., Kahmann, J., Felicetti, B., Wood, M., Scheich, C. | | Deposit date: | 2015-08-14 | | Release date: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors.
Acs Med.Chem.Lett., 6, 2015
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5JR9 | | CRYSTAL STRUCTURE OF APO-NEC3PO | | Descriptor: | NEQ131 | | Authors: | Zhang, J., Gan, J. | | Deposit date: | 2016-05-06 | | Release date: | 2016-09-28 | | Last modified: | 2016-11-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
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