Author results

2LSP
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SOLUTION STRUCTURES OF BRD4 SECOND BROMODOMAIN WITH NF-KB-K310AC PEPTIDE
Descriptor:NF-kB-K310ac peptide, Bromodomain-containing protein 4
Authors:Zhang, G., Liu, R., Zhong, Y., Plotnikov, A.N., Zhang, W., Rusinova, E., Gerona-Nevarro, G., Moshkina, N., Joshua, J., Chuang, P.Y., Ohlmeyer, M., He, J., Zhou, M.-M.
Deposit date:2012-05-03
Release date:2012-07-18
Last modified:2013-08-28
Method:SOLUTION NMR
Cite:Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
J.Biol.Chem., 287, 2012
1SWV
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CRYSTAL STRUCTURE OF THE D12A MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM
Descriptor:phosphonoacetaldehyde hydrolase, MAGNESIUM ION
Authors:Zhang, G., Morais, M.C., Dai, J., Zhang, W., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2004-03-30
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
1SWW
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CRYSTAL STRUCTURE OF THE PHOSPHONOACETALDEHYDE HYDROLASE D12A MUTANT COMPLEXED WITH MAGNESIUM AND SUBSTRATE PHOSPHONOACETALDEHYDE
Descriptor:phosphonoacetaldehyde hydrolase, MAGNESIUM ION, PHOSPHONOACETALDEHYDE
Authors:Zhang, G., Morais, M.C., Dai, J., Zhang, W., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2004-03-30
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
1AB8
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RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX
Descriptor:ADENYLYL CYCLASE, FORSKOLIN
Authors:Zhang, G., Hurley, J.H.
Deposit date:1997-02-04
Release date:1997-05-15
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the adenylyl cyclase catalytic core.
Nature, 386, 1997
1BDF
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STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE ALPHA SUBUNIT N-TERMINAL DOMAIN
Descriptor:RNA POLYMERASE ALPHA SUBUNIT
Authors:Zhang, G., Darst, S.A.
Deposit date:1998-05-08
Release date:1999-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Escherichia coli RNA polymerase alpha subunit amino-terminal domain.
Science, 281, 1998
1PTQ
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PROTEIN KINASE C DELTA CYS2 DOMAIN
Descriptor:PROTEIN KINASE C DELTA TYPE, ZINC ION
Authors:Zhang, G., Hurley, J.H.
Deposit date:1995-05-11
Release date:1995-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
Cell(Cambridge,Mass.), 81, 1995
1PTR
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PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL-13-ACETATE
Descriptor:PROTEIN KINASE C DELTA TYPE, ZINC ION, 13-ACETYLPHORBOL
Authors:Zhang, G., Hurley, J.H.
Deposit date:1995-05-11
Release date:1995-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
Cell(Cambridge,Mass.), 81, 1995
1ZOL
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NATIVE BETA-PGM
Descriptor:beta-phosphoglucomutase, MAGNESIUM ION
Authors:Zhang, G., Tremblay, L.W., Dai, J., Wang, L., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2005-05-13
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis
Biochemistry, 44, 2005
1OQD
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CRYSTAL STRUCTURE OF STALL-1 AND BCMA
Descriptor:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
Authors:Zhang, G.
Deposit date:2003-03-07
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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CRYSTAL STRUCTURE OF STALL-1 WITH BAFF-R
Descriptor:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
Authors:Zhang, G.
Deposit date:2003-03-07
Release date:2003-05-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1HSJ
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SARR MBP FUSION STRUCTURE
Descriptor:FUSION PROTEIN CONSISTING OF STAPHYLOCOCCUS ACCESSORY REGULATOR PROTEIN R AND MALTOSE BINDING PROTEIN, alpha-D-glucopyranose
Authors:Zhang, G.
Deposit date:2000-12-26
Release date:2001-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the SarR protein from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 98, 2001
2P5B
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THE COMPLEX STRUCTURE OF JMJD2A AND TRIMETHYLATED H3K36 PEPTIDE
Descriptor:JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ...
Authors:Zhang, G., Chen, Z., Zang, J., Hong, X., Shi, Y.
Deposit date:2007-03-14
Release date:2007-06-12
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
1FEZ
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THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG
Descriptor:PHOSPHONOACETALDEHYDE HYDROLASE, MAGNESIUM ION, TUNGSTATE(VI)ION
Authors:Morais, M.C., Zhang, W., Baker, A.S., Zhang, G., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2000-07-24
Release date:2000-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily.
Biochemistry, 39, 2000
1RQL
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CRYSTAL STRUCTURE OF PHOSPONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM AND THE INHIBITOR VINYL SULFONATE
Descriptor:Phosphonoacetaldehyde Hydrolase, MAGNESIUM ION, VINYLSULPHONIC ACID
Authors:Morais, M.C., Zhang, G., Zhang, W., Olsen, D.B., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2003-12-05
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis
J.Biol.Chem., 279, 2004
1RQN
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PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM
Descriptor:Phosphonoacetaldehyde Hydrolase, MAGNESIUM ION
Authors:Morais, M.C., Zhang, G., Zhang, W., Olsen, D.B., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2003-12-05
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis
J.Biol.Chem., 279, 2004
7CJF
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CRYSTAL STRUCTURE OF SARS-COV-2 RBD IN COMPLEX WITH A NEUTRALIZING ANTIBODY FAB
Descriptor:antibody heavy chain, antibody light chain, Spike glycoprotein, ...
Authors:Guo, Y., Li, X., Zhang, G., Fu, D., Schweizer, L., Zhang, H., Rao, Z.
Deposit date:2020-07-10
Release date:2020-11-11
Method:X-RAY DIFFRACTION (2.108 Å)
Cite:Crystal structure of SARS-CoV-2 RBD in complex with an antibody Fab
To Be Published
1LVH
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THE STRUCTURE OF PHOSPHORYLATED BETA-PHOSPHOGLUCOMUTASE FROM LACTOCCOCUS LACTIS TO 2.3 ANGSTROM RESOLUTION
Descriptor:beta-phosphoglucomutase, MAGNESIUM ION
Authors:Lahiri, S.D., Zhang, G., Dunaway-Mariano, D., Allen, K.N.
Deposit date:2002-05-28
Release date:2002-08-14
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis.
Biochemistry, 41, 2002
2HFR
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SOLUTION STRUCTURE OF ANTIMICROBIAL PEPTIDE FOWLICIDIN 3
Descriptor:Fowlicidin-3
Authors:Bommineni, Y.R., Dai, H., Gong, Y., Prakash, O., Zhang, G.
Deposit date:2006-06-26
Release date:2007-04-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities.
Febs J., 274, 2007
2LQV
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YEBF
Descriptor:Protein yebF
Authors:Prehna, G., Zhang, G., Gong, X., Duszyk, M., Okon, M., Mcintosh, L.P., Weiner, J.H., Strynadka, N.C.J.
Deposit date:2012-03-16
Release date:2012-06-13
Last modified:2012-07-25
Method:SOLUTION NMR
Cite:A Protein Export Pathway Involving Escherichia coli Porins.
Structure, 20, 2012
6AVS
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC MONOMETHYL-ARGININE (MMA)
Descriptor:Lysine-specific demethylase 8, ZINC ION, (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid
Authors:Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
Deposit date:2017-09-04
Release date:2018-02-28
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6AX3
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC DIMETHYL-ARGININE (SDMA)
Descriptor:Lysine-specific demethylase 8, N3, N4-DIMETHYLARGININE, ...
Authors:Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
Deposit date:2017-09-06
Release date:2018-02-28
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6MEV
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STRUCTURE OF JMJD6 BOUND TO MONO-METHYL ARGININE.
Descriptor:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, 2-OXOGLUTARIC ACID, FE (III) ION, ...
Authors:Lee, S., Zhang, G.
Deposit date:2018-09-07
Release date:2019-09-18
Last modified:2020-04-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Elife, 9, 2020
6R8I
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PP4R3A EVH1 DOMAIN BOUND TO FXXP MOTIF
Descriptor:Serine/threonine-protein phosphatase 4 regulatory subunit 3A, SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER
Authors:Ueki, Y., Kruse, T., Weisser, M.B., Sundell, G.N., Yoo Larsen, M.S., Lopez Mendez, B., Jenkins, N.P., Garvanska, D.H., Cressey, L., Zhang, G., Davey, N., Montoya, G., Ivarsson, Y., Kettenbach, A., Nilsson, J.
Deposit date:2019-04-02
Release date:2019-10-16
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.517 Å)
Cite:A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 76, 2019
2W7X
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CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019
Descriptor:SERINE/THREONINE-PROTEIN KINASE CHK2, N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide, MAGNESIUM ION, ...
Authors:Jobson, A.G., Lountos, G.T., Lorenzi, P.L., Llamas, J., Connelly, J., Tropea, J.E., Onda, A., Kondapaka, S., Zhang, G., Caplen, N.J., Caredellina, J.H., Monks, A., Self, C., Waugh, D.S., Shoemaker, R.H., Pommier, Y.
Deposit date:2009-01-06
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Cellular Inhibition of Chk2 Kinase and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor Pv1019.
J.Pharmacol.Exp.Ther., 331, 2009
2YIQ
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STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322
Descriptor:SERINE/THREONINE-PROTEIN KINASE CHK2, (E)-5-(1-(2-CARBAMIMIDOYLHYDRAZONO)ETHYL)-N-(1H-INDOL-6-YL)-1H-INDOLE-2-CARBOXAMIDE, NITRATE ION
Authors:Lountos, G.T., Jobson, A.G., Tropea, J.E., Self, C., Zhang, G., Pommier, Y., Shoemaker, R.H., Waugh, D.S.
Deposit date:2011-05-16
Release date:2011-09-07
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:X-Ray Structures of Checkpoint Kinase 2 in Complex with Inhibitors that Target its Gatekeeper-Dependent Hydrophobic Pocket.
FEBS Lett., 585, 2011
171588
PDB entries from 2020-11-25