5TEO
 
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7R7P
 | | Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6) | | Descriptor: | 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | | Authors: | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | | Deposit date: | 2021-06-25 | | Release date: | 2023-02-15 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
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7R7Q
 | | Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6) | | Descriptor: | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | | Authors: | Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T. | | Deposit date: | 2021-06-25 | | Release date: | 2023-02-15 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
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6BHS
 | | HIV-1 CA hexamer in complex with IP6, hexagonal crystal form | | Descriptor: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | | Deposit date: | 2017-10-31 | | Release date: | 2018-08-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.984 Å) | | Cite: | Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
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5I4T
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7ZUD
 | | Crystal structure of HIV-1 capsid IP6-CPSF6 complex | | Descriptor: | Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE | | Authors: | Nicastro, G, Taylor, I.A. | | Deposit date: | 2022-05-12 | | Release date: | 2022-07-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.93 Å) | | Cite: | CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1.
J.Mol.Biol., 434, 2022
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6BHR
 | | HIV-1 immature CTD-SP1 hexamer in complex with IP6 | | Descriptor: | Capsid protein p24,Spacer peptide 1, INOSITOL HEXAKISPHOSPHATE | | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | | Deposit date: | 2017-10-31 | | Release date: | 2018-08-08 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.908 Å) | | Cite: | Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
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6BHT
 | | HIV-1 CA hexamer in complex with IP6, orthorhombic crystal form | | Descriptor: | Capsid protein p24, INOSITOL HEXAKISPHOSPHATE | | Authors: | Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O. | | Deposit date: | 2017-10-31 | | Release date: | 2018-08-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.689 Å) | | Cite: | Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
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7KZH
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7TGQ
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7URT
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7URN
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8EET
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8EEP
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8EUS
 | | Crystal structure of NPC1 luminal domain C | | Descriptor: | NPC intracellular cholesterol transporter 1 | | Authors: | Odongo, L, Pornillos, O. | | Deposit date: | 2022-10-19 | | Release date: | 2023-02-22 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Purification and structure of luminal domain C of human Niemann-Pick C1 protein.
Acta Crystallogr.,Sect.F, 79, 2023
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8EJL
 | | Structure of HIV-1 capsid declination in complex with CPSF6-FG peptide | | Descriptor: | Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein | | Authors: | Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T, dos Santos, N.F.B. | | Deposit date: | 2022-09-17 | | Release date: | 2023-02-15 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
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