Author results

2FGG
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CRYSTAL STRUCTURE OF RV2632C
Descriptor:Hypothetical protein Rv2632c/MT2708
Authors:Yu, M., Bursey, E.H., Radhakannan, T., Segelke, B.W., Lekin, T., Toppani, D., Kim, C.Y., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-12-21
Release date:2006-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Rv2632c
To be Published
2IB0
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CRYSTAL STRUCTURE OF A CONSERVED HYPOTHETICAL PROTEIN, RV2844, FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN
Authors:Yu, M., Bursey, E.H., Radhakannan, T., Kim, C.Y., Kaviratne, T., Woodruff, T., Segelke, B.W., Lekin, T., Toppani, D., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2006-09-08
Release date:2006-09-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis
To be Published
2NYX
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CRYSTAL STRUCTURE OF RV1404 FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Probable transcriptional regulatory protein, Rv1404
Authors:Yu, M., Bursey, E.H., Radhakannan, R., Kim, C.-Y., Kaviratne, T., Woodruff, T., Segelke, B.W., Lekin, T., Toppani, D., Terwilliger, T.C., Hung, L.-W., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2006-11-21
Release date:2006-12-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of RV1404 from Mycobacterium tuberculosis
To be Published
3FMS
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CRYSTAL STRUCTURE OF TM0439, A GNTR TRANSCRIPTIONAL REGULATOR
Descriptor:Transcriptional regulator, GntR family, NICKEL (II) ION, ...
Authors:Zheng, M., Cooper, D.R., Yu, M., Hung, L.-W., Derewenda, U., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2008-12-22
Release date:2009-02-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
1HGV
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FILAMENTOUS BACTERIOPHAGE PH75
Descriptor:PH75 INOVIRUS MAJOR COAT PROTEIN
Authors:Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
Deposit date:2000-12-15
Release date:2001-06-01
Last modified:2011-07-13
Method:FIBER DIFFRACTION (2.4 Å)
Cite:The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1HGZ
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FILAMENTOUS BACTERIOPHAGE PH75
Descriptor:PH75 INOVIRUS MAJOR COAT PROTEIN
Authors:Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
Deposit date:2000-12-17
Release date:2001-06-01
Last modified:2011-07-13
Method:FIBER DIFFRACTION (2.4 Å)
Cite:The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1HH0
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FILAMENTOUS BACTERIOPHAGE PH75
Descriptor:PH75 INOVIRUS MAJOR COAT PROTEIN
Authors:Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
Deposit date:2000-12-17
Release date:2001-06-01
Last modified:2011-07-13
Method:FIBER DIFFRACTION (2.4 Å)
Cite:The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1ZSN
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
Descriptor:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 5-CHLORO-2-(2-CHLORO-4-NITROPHENOXY)PHENOL
Authors:Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
Deposit date:2005-05-24
Release date:2006-05-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.992 Å)
Cite:Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZW1
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
Descriptor:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(4-AMINO-2-CHLOROPHENOXY)-5-CHLOROPHENOL
Authors:Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
Deposit date:2005-06-03
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZXB
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
Descriptor:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)-N-METHYLBENZAMIDE
Authors:Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
Deposit date:2005-06-07
Release date:2006-06-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZXL
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
Descriptor:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-[3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)PHENYL]MORPHOLINE-4-CARBOXAMIDE
Authors:Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
Deposit date:2005-06-08
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
2FOI
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE.
Descriptor:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(2,4-DICHLOROPHENOXY)-2'-METHYLBIPHENYL-3-OL
Authors:Freundlich, J.S., Shieh, H., Anderson, J.W., Kuo, M., Yu, M., Valderramos, J., Karagyozov, L., Tsai, H., Lucumi, E., Jacobs Jr., W.R., Schiehser, G.A., Jacobus, D.P., Fidock, D.A., Sacchettini, J.C.
Deposit date:2006-01-13
Release date:2007-01-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy.
J.Biol.Chem., 282, 2007
2FSX
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CRYSTAL STRUCTURE OF RV0390 FROM M. TUBERCULOSIS
Descriptor:COG0607: Rhodanese-related sulfurtransferase, BROMIDE ION, SULFATE ION
Authors:Bursey, E.H., Radhakannan, T., Yu, M., Segelke, B.W., Lekin, T., Toppani, D., Chang, Y.-B., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.-W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-01-23
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Rv0390 from Mycobacterium tuberculosis
To be Published
2G5F
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THE STRUCTURE OF MBTI FROM MYCOBACTERIUM TUBERCULOSIS, THE FIRST ENZYME IN THE SYNTHESIS OF MYCOBACTIN, REVEALS IT TO BE A SALICYLATE SYNTHASE
Descriptor:COG0147: Anthranilate/para-aminobenzoate synthases component I, PYRUVIC ACID, IMIDAZOLE, ...
Authors:Harrison, A.J., Lott, J.S., Yu, M., Ramsay, R., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2006-02-22
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
J.Bacteriol., 188, 2006
2H5X
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RUVA FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Holliday junction ATP-dependent DNA helicase ruvA, GLYCEROL
Authors:Prabu, J.R., Thamotharan, S., Khanduja, J.S., Alipio, E.Z., Kim, C.Y., Waldo, G.S., Terwilliger, T.C., Segelke, B., Lekin, T., Toppani, D., Hung, L.W., Yu, M., Bursey, E., Muniyappa, K., Chandra, N.R., Vijayan, M.
Deposit date:2006-05-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2NQ8
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MALARIAL ENOYL ACYL ACP REDUCTASE BOUND WITH INH-NAD ADDUCT
Descriptor:Enoyl-acyl carrier reductase, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE
Authors:Freundlich, J.S., Yu, M., Lucumi, E., Kuo, M., Tsai, H.C., Valderramos, J.C., Karagyozov, L., Jacobs Jr., W.R., Schiehser, G.A., Fidock, D.A., Jacobus, D.P., Sacchettini, J.C.
Deposit date:2006-10-30
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy
J.Biol.Chem., 282, 2007
5LPI
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STRUCTURE OF THE ZINC FINGER ARRAY OF CEP104
Descriptor:Centrosomal protein of 104 kDa, ZINC ION
Authors:van Breugel, M., Yu, M., al Jassar, C.
Deposit date:2016-08-13
Release date:2017-01-11
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
1G7P
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CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Apostolopoulos, V., Yu, M., Corper, A.L., Li, W., McKenzie, I.F., Teyton, L., Wilson, I.A.
Deposit date:2000-11-13
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.
J.Mol.Biol., 318, 2002
1G7Q
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CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND MUC1 VNTR PEPTIDE SAPDTRPA
Descriptor:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Apostolopoulos, V., Yu, M., Corper, A.L., Teyton, L., Pietersz, G.A., McKenzie, I.F., Wilson, I.A.
Deposit date:2000-11-13
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.
J.Mol.Biol., 318, 2002
1OZP
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CRYSTAL STRUCTURE OF RV0819 FROM MYCOBACTERIUM TUBERCULOSIS MSHD-MYCOTHIOL SYNTHASE ACETYL-COENZYME A COMPLEX.
Descriptor:hypothetical protein Rv0819, ACETYL COENZYME *A
Authors:Vetting, M.W., Roderick, S.L., Yu, M., Blanchard, J.S.
Deposit date:2003-04-09
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases.
Protein Sci., 12, 2003
1P0H
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CRYSTAL STRUCTURE OF RV0819 FROM MYCOBACTERIUM TUBERCULOSIS MSHD-MYCOTHIOL SYNTHASE COENZYME A COMPLEX
Descriptor:hypothetical protein Rv0819, COENZYME A, ACETYL COENZYME *A
Authors:Vetting, M.W., Roderick, S.L., Yu, M., Blanchard, J.S.
Deposit date:2003-04-10
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases.
Protein Sci., 12, 2003
1XVW
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CRYSTAL STRUCTURE OF AHPE FROM MYCOBACTERIUM TUBERCULOSIS, A 1-CYS PEROXIREDOXIN
Descriptor:Hypothetical protein Rv2238c/MT2298
Authors:Li, S., Peterson, N.A., Kim, M.Y., Kim, C.Y., Hung, L.W., Yu, M., Lekin, T., Segelke, B.W., Lott, J.S., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-10-28
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin
J.Mol.Biol., 346, 2005
1XXU
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CRYSTAL STRUCTURE OF AHPE FROM MYCROBACTERIUM TUBERCULOSIS, A 1-CYS PEROXIREDOXIN
Descriptor:Hypothetical protein Rv2238c/MT2298
Authors:Li, S., Peterson, N.A., Kim, M.Y., Kim, C.Y., Hung, L.W., Yu, M., Lekin, T., Segelke, B.W., Lott, J.S., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-11-08
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin
J.Mol.Biol., 346, 2005
1ZXT
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CRYSTAL STRUCTURE OF A VIRAL CHEMOKINE
Descriptor:functional macrophage inflammatory protein 1-alpha homolog
Authors:Luz, J.G., Yu, M., Su, Y., Wu, Z., Zhou, Z., Sun, R., Wilson, I.A.
Deposit date:2005-06-08
Release date:2005-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
2C27
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THE STRUCTURE OF MYCOTHIOL SYNTHASE IN COMPLEX WITH DES- ACETYLMYCOTHIOL AND COENZYMEA.
Descriptor:MYCOTHIOL SYNTHASE, (2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE, ACETYL COENZYME *A, ...
Authors:Vetting, M.W., Yu, M., Rendle, P.M., Blanchard, J.S.
Deposit date:2005-09-26
Release date:2005-12-01
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Substrate-Induced Conformational Change of Mycobacterium Tuberculosis Mycothiol Synthase.
J.Biol.Chem., 281, 2006