Author results

2FGG
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CRYSTAL STRUCTURE OF RV2632C
分子名称:Hypothetical protein Rv2632c/MT2708
著者Yu, M., Bursey, E.H., Radhakannan, T., Segelke, B.W., Lekin, T., Toppani, D., Kim, C.Y., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC)
登録日2005-12-21
公開日2006-02-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Rv2632c
To be Published
2IB0
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CRYSTAL STRUCTURE OF A CONSERVED HYPOTHETICAL PROTEIN, RV2844, FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN
著者Yu, M., Bursey, E.H., Radhakannan, T., Kim, C.Y., Kaviratne, T., Woodruff, T., Segelke, B.W., Lekin, T., Toppani, D., Terwilliger, T.C., Hung, L.W., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2006-09-08
公開日2006-09-26
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a conserved hypothetical protein, rv2844, from Mycobacterium tuberculosis
To be Published
2NYX
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CRYSTAL STRUCTURE OF RV1404 FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Probable transcriptional regulatory protein, Rv1404
著者Yu, M., Bursey, E.H., Radhakannan, R., Kim, C.-Y., Kaviratne, T., Woodruff, T., Segelke, B.W., Lekin, T., Toppani, D., Terwilliger, T.C., Hung, L.-W., TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2006-11-21
公開日2006-12-05
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of RV1404 from Mycobacterium tuberculosis
To be Published
1HGV
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FILAMENTOUS BACTERIOPHAGE PH75
分子名称:PH75 INOVIRUS MAJOR COAT PROTEIN
著者Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
登録日2000-12-15
公開日2001-06-01
最終更新日2011-07-13
実験手法FIBER DIFFRACTION (2.4 Å)
主引用文献The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1HGZ
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FILAMENTOUS BACTERIOPHAGE PH75
分子名称:PH75 INOVIRUS MAJOR COAT PROTEIN
著者Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
登録日2000-12-17
公開日2001-06-01
最終更新日2011-07-13
実験手法FIBER DIFFRACTION (2.4 Å)
主引用文献The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1HH0
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FILAMENTOUS BACTERIOPHAGE PH75
分子名称:PH75 INOVIRUS MAJOR COAT PROTEIN
著者Pederson, D.M., Welsh, L.C., Marvin, D.A., Sampson, M., Perham, R.N., Yu, M., Slater, M.R.
登録日2000-12-17
公開日2001-06-01
最終更新日2011-07-13
実験手法FIBER DIFFRACTION (2.4 Å)
主引用文献The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus
J.Mol.Biol., 309, 2001
1ZSN
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
分子名称:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 5-CHLORO-2-(2-CHLORO-4-NITROPHENOXY)PHENOL
著者Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
登録日2005-05-24
公開日2006-05-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.992 Å)
主引用文献Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZW1
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
分子名称:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2-(4-AMINO-2-CHLOROPHENOXY)-5-CHLOROPHENOL
著者Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
登録日2005-06-03
公開日2006-06-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZXB
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
分子名称:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)-N-METHYLBENZAMIDE
著者Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
登録日2005-06-07
公開日2006-06-13
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZXL
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE. PART 1:4'-SUBSTITUTED TRICLOSAN DERIVATIVES
分子名称:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-[3-CHLORO-4-(4-CHLORO-2-HYDROXYPHENOXY)PHENYL]MORPHOLINE-4-CARBOXAMIDE
著者Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Lucumi, E., Kuo, M., Schiehser, G.A., Jacobus, D.P., Jacobs Jr., W.R., Fidock, D.A., Sacchettini, J.C.
登録日2005-06-08
公開日2006-06-13
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
2FOI
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SYNTHESIS, BIOLOGICAL ACTIVITY, AND X-RAY CRYSTAL STRUCTURAL ANALYSIS OF DIARYL ETHER INHIBITORS OF MALARIAL ENOYL ACP REDUCTASE.
分子名称:enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 4-(2,4-DICHLOROPHENOXY)-2'-METHYLBIPHENYL-3-OL
著者Freundlich, J.S., Shieh, H., Anderson, J.W., Kuo, M., Yu, M., Valderramos, J., Karagyozov, L., Tsai, H., Lucumi, E., Jacobs Jr., W.R., Schiehser, G.A., Jacobus, D.P., Fidock, D.A., Sacchettini, J.C.
登録日2006-01-13
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy.
J.Biol.Chem., 282, 2007
2FSX
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CRYSTAL STRUCTURE OF RV0390 FROM M. TUBERCULOSIS
分子名称:COG0607: Rhodanese-related sulfurtransferase, BROMIDE ION, SULFATE ION
著者Bursey, E.H., Radhakannan, T., Yu, M., Segelke, B.W., Lekin, T., Toppani, D., Chang, Y.-B., Kaviratne, T., Woodruff, T., Terwilliger, T.C., Hung, L.-W., TB Structural Genomics Consortium (TBSGC)
登録日2006-01-23
公開日2006-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Rv0390 from Mycobacterium tuberculosis
To be Published
2G5F
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THE STRUCTURE OF MBTI FROM MYCOBACTERIUM TUBERCULOSIS, THE FIRST ENZYME IN THE SYNTHESIS OF MYCOBACTIN, REVEALS IT TO BE A SALICYLATE SYNTHASE
分子名称:COG0147: Anthranilate/para-aminobenzoate synthases component I, PYRUVIC ACID, IMIDAZOLE, ...
著者Harrison, A.J., Lott, J.S., Yu, M., Ramsay, R., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
登録日2006-02-22
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
J.Bacteriol., 188, 2006
2H5X
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RUVA FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Holliday junction ATP-dependent DNA helicase ruvA, GLYCEROL
著者Prabu, J.R., Thamotharan, S., Khanduja, J.S., Alipio, E.Z., Kim, C.Y., Waldo, G.S., Terwilliger, T.C., Segelke, B., Lekin, T., Toppani, D., Hung, L.W., Yu, M., Bursey, E., Muniyappa, K., Chandra, N.R., Vijayan, M.
登録日2006-05-28
公開日2006-08-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2NQ8
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MALARIAL ENOYL ACYL ACP REDUCTASE BOUND WITH INH-NAD ADDUCT
分子名称:Enoyl-acyl carrier reductase, ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE
著者Freundlich, J.S., Yu, M., Lucumi, E., Kuo, M., Tsai, H.C., Valderramos, J.C., Karagyozov, L., Jacobs Jr., W.R., Schiehser, G.A., Fidock, D.A., Jacobus, D.P., Sacchettini, J.C.
登録日2006-10-30
公開日2007-07-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy
J.Biol.Chem., 282, 2007
3FMS
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CRYSTAL STRUCTURE OF TM0439, A GNTR TRANSCRIPTIONAL REGULATOR
分子名称:Transcriptional regulator, GntR family, NICKEL (II) ION, ...
著者Zheng, M., Cooper, D.R., Yu, M., Hung, L.-W., Derewenda, U., Derewenda, Z.S., Integrated Center for Structure and Function Innovation (ISFI)
登録日2008-12-22
公開日2009-02-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
5LPI
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STRUCTURE OF THE ZINC FINGER ARRAY OF CEP104
分子名称:Centrosomal protein of 104 kDa, ZINC ION
著者van Breugel, M., Yu, M., al Jassar, C.
登録日2016-08-13
公開日2017-01-11
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
1G7P
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CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE
分子名称:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
著者Apostolopoulos, V., Yu, M., Corper, A.L., Li, W., McKenzie, I.F., Teyton, L., Wilson, I.A.
登録日2000-11-13
公開日2002-07-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.
J.Mol.Biol., 318, 2002
1G7Q
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CRYSTAL STRUCTURE OF MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND MUC1 VNTR PEPTIDE SAPDTRPA
分子名称:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
著者Apostolopoulos, V., Yu, M., Corper, A.L., Teyton, L., Pietersz, G.A., McKenzie, I.F., Wilson, I.A.
登録日2000-11-13
公開日2002-07-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.
J.Mol.Biol., 318, 2002
1OZP
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CRYSTAL STRUCTURE OF RV0819 FROM MYCOBACTERIUM TUBERCULOSIS MSHD-MYCOTHIOL SYNTHASE ACETYL-COENZYME A COMPLEX.
分子名称:hypothetical protein Rv0819, ACETYL COENZYME *A
著者Vetting, M.W., Roderick, S.L., Yu, M., Blanchard, J.S.
登録日2003-04-09
公開日2003-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases.
Protein Sci., 12, 2003
1P0H
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CRYSTAL STRUCTURE OF RV0819 FROM MYCOBACTERIUM TUBERCULOSIS MSHD-MYCOTHIOL SYNTHASE COENZYME A COMPLEX
分子名称:hypothetical protein Rv0819, COENZYME A, ACETYL COENZYME *A
著者Vetting, M.W., Roderick, S.L., Yu, M., Blanchard, J.S.
登録日2003-04-10
公開日2003-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases.
Protein Sci., 12, 2003
1XVW
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CRYSTAL STRUCTURE OF AHPE FROM MYCOBACTERIUM TUBERCULOSIS, A 1-CYS PEROXIREDOXIN
分子名称:Hypothetical protein Rv2238c/MT2298
著者Li, S., Peterson, N.A., Kim, M.Y., Kim, C.Y., Hung, L.W., Yu, M., Lekin, T., Segelke, B.W., Lott, J.S., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
登録日2004-10-28
公開日2005-02-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin
J.Mol.Biol., 346, 2005
1XXU
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CRYSTAL STRUCTURE OF AHPE FROM MYCROBACTERIUM TUBERCULOSIS, A 1-CYS PEROXIREDOXIN
分子名称:Hypothetical protein Rv2238c/MT2298
著者Li, S., Peterson, N.A., Kim, M.Y., Kim, C.Y., Hung, L.W., Yu, M., Lekin, T., Segelke, B.W., Lott, J.S., Baker, E.N., TB Structural Genomics Consortium (TBSGC)
登録日2004-11-08
公開日2005-02-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin
J.Mol.Biol., 346, 2005
1ZXT
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CRYSTAL STRUCTURE OF A VIRAL CHEMOKINE
分子名称:functional macrophage inflammatory protein 1-alpha homolog
著者Luz, J.G., Yu, M., Su, Y., Wu, Z., Zhou, Z., Sun, R., Wilson, I.A.
登録日2005-06-08
公開日2005-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of viral macrophage inflammatory protein I encoded by Kaposi's sarcoma-associated herpesvirus at 1.7A.
J.Mol.Biol., 352, 2005
2C27
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THE STRUCTURE OF MYCOTHIOL SYNTHASE IN COMPLEX WITH DES- ACETYLMYCOTHIOL AND COENZYMEA.
分子名称:MYCOTHIOL SYNTHASE, (2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE, ACETYL COENZYME *A, ...
著者Vetting, M.W., Yu, M., Rendle, P.M., Blanchard, J.S.
登録日2005-09-26
公開日2005-12-01
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Substrate-Induced Conformational Change of Mycobacterium Tuberculosis Mycothiol Synthase.
J.Biol.Chem., 281, 2006