Author results

1PLS
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SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:PLECKSTRIN HOMOLOGY DOMAIN
Authors:Yoon, H.S., Hajduk, P.J., Petros, A.M., Olejniczak, E.T., Meadows, R.P., Fesik, S.W.
Deposit date:1994-05-03
Release date:1995-06-03
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of a pleckstrin-homology domain.
Nature, 369, 1994
5YSO
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CRYSTAL STRUCTURE OF ESTROGEN RELATED RECEPTOR-3 (ERR-GAMMA) LIGAND BINDING DOMAIN WITH DN200434
Descriptor:Estrogen-related receptor gamma, 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol
Authors:Cho, S.J., Chin, J.W., Yoon, H.S., Jeon, Y.H., Bae, J.H., Song, J.Y.
Deposit date:2017-11-14
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:A novel orally active inverse agonist of estrogen-related receptor gamma (ERRg), DN200434, enhances sodium iodide symporter function in mice with anaplastic thyroid cancer
To Be Published
2OFN
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SOLUTION STRUCTURE OF FK506-BINDING DOMAIN (FKBD)OF FKBP35 FROM PLASMODIUM FALCIPARUM
Descriptor:70 kDa peptidylprolyl isomerase, putative
Authors:Kang, C.B., Ye, H., Yoon, H.R., Yoon, H.S.
Deposit date:2007-01-04
Release date:2007-12-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of FK506 binding domain (FKBD) of Plasmodium falciparum FK506 binding protein 35 (PfFKBP35).
Proteins, 70, 2007
2MF9
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN FKBP38 (FKBP38NTD)
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP8
Authors:Kang, C., Ye, H., Simon, B., Sattler, M., Yoon, H.S.
Deposit date:2013-10-08
Release date:2013-11-06
Method:SOLUTION NMR
Cite:Functional role of the flexible N-terminal extension of FKBP38 in catalysis.
Sci Rep, 3, 2013
3PA7
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CRYSTAL STRUCTURE OF FKBP FROM PLASMODIUM VIVAX IN COMPLEX WITH TETRAPEPTIDE ALPF
Descriptor:70 kDa peptidylprolyl isomerase, putative, 4-mer Peptide ALPF
Authors:Balakrishna, A.M., Alag, R., Yoon, H.S.
Deposit date:2010-10-18
Release date:2012-02-29
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax
EUKARYOTIC CELL, 12, 2013
1DHM
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DNA-BINDING DOMAIN OF E2 FROM HUMAN PAPILLOMAVIRUS-31, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:E2 PROTEIN
Authors:Liang, H., Petros, A.P., Meadows, R.P., Yoon, H.S., Egan, D.A., Walter, K., Holzman, T.F., Robins, T., Fesik, S.W.
Deposit date:1995-08-15
Release date:1996-12-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of a human papillomavirus E2 protein: evidence for flexible DNA-binding regions.
Biochemistry, 35, 1996
1G5M
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HUMAN BCL-2, ISOFORM 1
Descriptor:PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN)
Authors:Petros, A.M., Medek, A., Nettesheim, D.G., Kim, D.H., Yoon, H.S., Swift, K., Matayoshi, E.D., Oltersdorf, T., Fesik, S.W.
Deposit date:2000-11-01
Release date:2001-03-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1GJH
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HUMAN BCL-2, ISOFORM 2
Descriptor:PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN)
Authors:Petros, A.M., Medek, A., Nettesheim, D.G., Kim, D.H., Yoon, H.S., Swift, K., Matayoshi, E.D., Oltersdorf, T., Fesik, S.W.
Deposit date:2001-05-31
Release date:2001-06-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the antiapoptotic protein bcl-2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1LXL
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NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
Descriptor:BCL-XL
Authors:Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
Deposit date:1996-04-04
Release date:1997-04-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1MAZ
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X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH
Descriptor:Bcl-2-like protein 1
Authors:Muchmore, S.W., Sattler, M., Liang, H., Meadows, R.P., Harlan, J.E., Yoon, H.S., Nettesheim, D., Chang, B.S., Thompson, C.B., Wong, S.L., Ng, S.C., Fesik, S.W.
Deposit date:1996-04-09
Release date:1997-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1TCE
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SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE
Descriptor:SHC, PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR
Authors:Zhou, M.-M., Meadows, R.P., Logan, T.M., Yoon, H.S., Wade, W.R., Ravichandran, K.S., Burakoff, S.J., Feisk, S.W.
Deposit date:1996-03-27
Release date:1997-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.
Proc.Natl.Acad.Sci.USA, 92, 1995
2KI3
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF FK506 BINDING DOMAIN FROM PLASMODIUM VIVAX
Descriptor:70 kDa peptidylprolyl isomerase, putative
Authors:Alag, R., Yoon, H.S., Shin, J.
Deposit date:2009-04-21
Release date:2010-04-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR assignments of the FK506-binding domain of FK506-binding protein 35 from Plasmodium vivax
Biomol.Nmr Assign., 3, 2009
2L9L
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NMR STRUCTURE OF THE MOUSE MFG-E8 C2 DOMAIN
Descriptor:Lactadherin
Authors:Ye, H., Yoon, H.S.
Deposit date:2011-02-21
Release date:2012-08-29
Last modified:2013-02-20
Method:SOLUTION NMR
Cite:NMR solution structure of C2 domain of MFG-E8 and insights into its molecular recognition with phosphatidylserine
Biochim.Biophys.Acta, 1828, 2013
2LAV
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NMR SOLUTION STRUCTURE OF HUMAN VACCINIA-RELATED KINASE 1
Descriptor:Vaccinia-related kinase 1
Authors:Shin, J., Yoon, H.S.
Deposit date:2011-03-21
Release date:2011-05-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Solution Structure of Human Vaccinia-related Kinase 1 (VRK1) Reveals the C-terminal Tail Essential for Its Structural Stability and Autocatalytic Activity.
J.Biol.Chem., 286, 2011
2VN1
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CRYSTAL STRUCTURE OF THE FK506-BINDING DOMAIN OF PLASMODIUM FALCIPARUM FKBP35 IN COMPLEX WITH FK506
Descriptor:70 KDA PEPTIDYLPROLYL ISOMERASE, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
Authors:Kotaka, M., Alag, R., Ye, H., Preiser, P.R., Yoon, H.S., Lescar, J.
Deposit date:2008-01-30
Release date:2008-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the Fk506 Binding Domain of Plasmodium Falciparum Fkbp35 in Complex with Fk506.
Biochemistry, 47, 2008
3IHZ
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CRYSTAL STRUCTURE OF THE FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH FK506
Descriptor:70 kDa peptidylprolyl isomerase, putative, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
Authors:Qureshi, I.A., Alag, R., Yoon, H.S., Lescar, J.
Deposit date:2009-07-31
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35
Protein Sci., 19, 2010
3NI6
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CRYSTAL STRUCTURE OF THE FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35
Descriptor:70 kDa peptidylprolyl isomerase, GLYCEROL
Authors:Qureshi, I.A., Yoon, H.S., Lescar, J.
Deposit date:2010-06-15
Release date:2011-04-27
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax
EUKARYOTIC CELL, 12, 2013
3UQI
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CRYSTALLOGRAPHIC STRUCTURE OF FKBP12 FROM AEDES AEGYPTI
Descriptor:FKBP-type peptidyl-prolyl cis-trans isomerase, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION
Authors:Sreekanth, R., Saw, K.Q., Yoon, H.S.
Deposit date:2011-11-20
Release date:2012-06-27
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:High-resolution crystal structure of FKBP12 from Aedes aegypti.
Protein Sci., 21, 2012
4ITZ
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CRYSTAL STRUCTURE OF THE FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH A TETRAPEPTIDE SUBSTRATE
Descriptor:70 kDa peptidylprolyl isomerase, substrate peptide, SULFATE ION
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2013-01-19
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax.
Eukaryot Cell, 12, 2013
4J4N
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CRYSTAL STRUCTURE OF FK506 BINDING DOMAIN OF PLASMODIUM FALCIPARUM FKBP35 IN COMPLEX WITH D44
Descriptor:FK506-binding protein (FKBP)-type peptidyl-propyl isomerase, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide
Authors:Sreekanth, R., Harikishore, A., Yoon, H.S.
Deposit date:2013-02-07
Release date:2013-09-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.
Sci Rep, 3, 2013
4J4O
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CRYSTAL STRUCTURE OF FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH D44
Descriptor:70 kDa peptidylprolyl isomerase, putative, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide, ...
Authors:Sreekanth, R., Harikishore, A., Yoon, H.S.
Deposit date:2013-02-07
Release date:2013-09-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.
Sci Rep, 3, 2013
4JYS
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CRYSTAL STRUCTURE OF FKBP25 FROM PLASMODIUM VIVAX
Descriptor:Peptidyl-prolyl cis-trans isomerase, IMIDAZOLE, CHLORIDE ION
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2013-04-01
Release date:2014-02-12
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity
Proteins, 82, 2014
4MGV
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CRYSTAL STRUCTURE OF FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH INHIBITOR D5
Descriptor:70 kDa peptidylprolyl isomerase, putative, N'-(1-adamantylcarbonyl)pyridine-4-carbohydrazide
Authors:Rajan, S., Harikishore, A., Yoon, H.S.
Deposit date:2013-08-29
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Adamantyl Derivative As a Potent Inhibitor of Plasmodium FK506 Binding Protein 35
ACS MED.CHEM.LETT., 4, 2013
4PPI
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CRYSTAL STRUCTURE OF BCL-XL HEXAMER
Descriptor:Bcl-2-like protein 1, GLYCEROL
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2014-02-27
Release date:2015-03-04
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport
Sci Rep, 5, 2015
4QVE
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CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BID BH3 DOMAIN
Descriptor:Bcl-2-like protein 1, Peptide from BH3-interacting domain death agonist, IMIDAZOLE
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2014-07-14
Release date:2015-06-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis
Proteins, 2015
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