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7UN6
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BU of 7un6 by Molmil
Complex of UBE2O with NAP1L1
Descriptor: (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1
Authors:Yip, M.C.J, Sedor, S.F, Shao, S.
Deposit date:2022-04-09
Release date:2022-08-03
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
7UN3
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BU of 7un3 by Molmil
Complex of UBE2O with NAP1L1 and ubiquitylated uL2
Descriptor: Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion
Authors:Yip, M.C.J, Sedor, S.F, Shao, S.
Deposit date:2022-04-08
Release date:2022-08-03
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
8SCB
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BU of 8scb by Molmil
Terminating ribosome with SRI-41315
Descriptor: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ...
Authors:Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S.
Deposit date:2023-04-05
Release date:2023-12-27
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Nat.Chem.Biol., 20, 2024
7RUC
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BU of 7ruc by Molmil
Metazoan pre-targeting GET complex with SGTA (cBUGGS)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
7RUA
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BU of 7rua by Molmil
Metazoan pre-targeting GET complex (cBUGG-out)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
7RU9
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BU of 7ru9 by Molmil
Metazoan pre-targeting GET complex (cBUGG-in)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
9BV1
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BU of 9bv1 by Molmil
M2A Midnolin-Proteasome (translocating)
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-19
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for nuclear protein degradation by the midnolin-proteasome pathway
To Be Published
9BV2
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BU of 9bv2 by Molmil
M2B Midnolin-Proteasome (translocating)
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-19
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for nuclear protein degradation by the midnolin-proteasome pathway
To Be Published
9BUI
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BU of 9bui by Molmil
M1A Midnolin-Proteasome (with Ubl)
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-17
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for nuclear protein degradation by the midnolin-proteasome pathway
To Be Published
9BV3
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BU of 9bv3 by Molmil
M1B Midnolin-Proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-19
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for nuclear protein degradation by the midnolin-proteasome pathway
To Be Published
9BW4
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BU of 9bw4 by Molmil
TXNL1-bound proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-20
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the TXNL1-bound proteasome
To Be Published
7UN8
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BU of 7un8 by Molmil
SfSTING with c-di-GMP single fiber
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12
Authors:Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J.
Deposit date:2022-04-09
Release date:2022-07-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of an active bacterial TIR-STING filament complex.
Nature, 608, 2022
7UN9
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BU of 7un9 by Molmil
SfSTING with c-di-GMP double fiber
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CD-NTase-associated protein 12
Authors:Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J.
Deposit date:2022-04-09
Release date:2022-07-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of an active bacterial TIR-STING filament complex.
Nature, 608, 2022
7UNA
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BU of 7una by Molmil
SfSTING with cGAMP (masked)
Descriptor: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CD-NTase-associated protein 12
Authors:Morehouse, B.R, Yip, M.C.J, Keszei, A.F.A, McNamara-Bordewick, N.K, Shao, S, Kranzusch, P.J.
Deposit date:2022-04-09
Release date:2022-07-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of an active bacterial TIR-STING filament complex.
Nature, 608, 2022
6VBU
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BU of 6vbu by Molmil
Structure of the bovine BBSome complex
Descriptor: BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ...
Authors:Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A.
Deposit date:2019-12-19
Release date:2020-01-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
6VBV
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BU of 6vbv by Molmil
Structure of the bovine BBSome:ARL6:GTP complex
Descriptor: ADP-ribosylation factor-like protein 6, BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, ...
Authors:Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A.
Deposit date:2019-12-19
Release date:2020-01-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and activation mechanism of the BBSome membrane protein trafficking complex.
Elife, 9, 2020
6MTE
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BU of 6mte by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2025-02-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTB
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BU of 6mtb by Molmil
Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTC
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BU of 6mtc by Molmil
Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTD
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BU of 6mtd by Molmil
Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel)
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2024-12-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
8S24
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BU of 8s24 by Molmil
Structure of the E3 ubiquitin ligase RNF213, determined by cryoEM
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, E3 ubiquitin-protein ligase RNF213, MAGNESIUM ION, ...
Authors:Naydenova, K, Randow, F.
Deposit date:2024-02-16
Release date:2024-10-09
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213.
Embo Rep., 25, 2024

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PDB entries from 2025-07-16

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