Author results

3JB9
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CRYO-EM STRUCTURE OF THE YEAST SPLICEOSOME AT 3.6 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-splicing factor spp42, Pre-mRNA-splicing factor cwf10, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Pre-mRNA-splicing factor prp5, Pre-mRNA-splicing factor cwf17, Pre-mRNA-processing protein 45, Pre-mRNA-processing factor 19 (E.C.6.3.2.-), Pre-mRNA-splicing factor cdc5, Pre-mRNA-splicing factor cwf2, Pre-mRNA-splicing factor cwf5, Pre-mRNA-splicing factor cwf19, Peptidyl-prolyl cis-trans isomerase ppi1 (E.C.5.2.1.8), Pre-mRNA-splicing factor cwf14, Pre-mRNA-processing factor 17, Pre-mRNA-splicing factor cwf15, Pre-mRNA-splicing factor cwf7, Pre-mRNA-splicing factor cwf4, Pre-mRNA-splicing factor cwf3, Pre-mRNA-splicing factor cwf11, U2 small nuclear ribonucleoprotein A', Probable U2 small nuclear ribonucleoprotein B'', unknown chain
Authors:Yan, C., Hang, J., Wan, R., Huang, M., Wong, C., Shi, Y.
Deposit date:2015-08-09
Release date:2015-09-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349, 2015
5GM6
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CRYO-EM STRUCTURE OF THE ACTIVATED SPLICEOSOME (BACT COMPLEX) AT 3.5 ANGSTROM RESOLUTION
Descriptor:Prp8, Brr2, Snu114, Rse1, Cus1, Prp11, Rds3, Ysf3, Prp46, Prp45, Ecm2, Cwc2, Cwc15, Bud31, Pml1, Snu17, Bud13, Prp2, Cwc22, Cwc24, Cwc27, Cef1, Hsh155, Clf1, Cwc21, Syf1, Hsh49, Syf2, Prp19, Snt309, Prp17, SmB, SmE, SmF, SmG, SmD3, SmD1, SmD2/RNA Complex
Authors:Yan, C., Wan, R., Bai, R., Huang, G., Shi, Y.
Deposit date:2016-07-12
Release date:2016-09-21
Modification date:2016-12-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Science, 353, 2016
5WSG
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CRYO-EM STRUCTURE OF THE CATALYTIC STEP II SPLICEOSOME (C* COMPLEX) AT 4.0 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, Pre-mRNA-splicing factor CWC21, Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor SLT11, Pre-mRNA-splicing factor CWC2, Pre-mRNA-splicing factor CWC15, Pre-mRNA-splicing factor BUD31, Pre-mRNA-splicing factor CWC22, Pre-mRNA-splicing factor CEF1,Cef1,Pre-mRNA-splicing factor CEF1, Pre-mRNA-splicing factor CLF1,Clf1, Pre-mRNA-splicing factor SYF2, Syf1, Pre-mRNA-processing factor 17, Pre-mRNA-processing factor 19, Pre-mRNA-splicing factor SNT309, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, U2 small nuclear ribonucleoprotein B'', U2 small nuclear ribonucleoprotein A', Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16, Pre-mRNA-splicing factor 18/RNA Complex
Authors:Yan, C., Wan, R., Bai, R., Huang, G., Shi, Y.
Deposit date:2016-12-07
Release date:2017-01-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a yeast step II catalytically activated spliceosome
Science, 355, 2017
3J8H
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STRUCTURE OF THE RABBIT RYANODINE RECEPTOR RYR1 IN COMPLEX WITH FKBP12 AT 3.8 ANGSTROM RESOLUTION
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A (E.C.5.2.1.8)
Authors:Yan, Z., Bai, X., Yan, C., Wu, J., Scheres, S.H.W., Shi, Y., Yan, N.
Deposit date:2014-10-26
Release date:2014-12-10
Modification date:2015-02-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
3RT0
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CRYSTAL STRUCTURE OF PYL10-HAB1 COMPLEX IN THE ABSENCE OF ABSCISIC ACID (ABA)
Descriptor:Protein phosphatase 2C 16 (E.C.3.1.3.16), Abscisic acid receptor PYL10
Authors:Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N.
Deposit date:2011-05-02
Release date:2011-06-22
Method:X-RAY DIFFRACTION (2.113 Å)
Cite:The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3RT2
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CRYSTAL STRUCTURE OF APO-PYL10
Descriptor:Abscisic acid receptor PYL10
Authors:Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N.
Deposit date:2011-05-02
Release date:2011-06-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3NS2
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HIGH-RESOLUTION STRUCTURE OF PYRABACTIN-BOUND PYL2
Descriptor:Abscisic acid receptor PYL2
Authors:Hao, Q., Yin, P., Yan, C., Yuan, X., Wang, J., Yan, N.
Deposit date:2010-07-01
Release date:2010-07-21
Modification date:2010-09-15
Method:X-RAY DIFFRACTION (1.634 Å)
Cite:Single amino acid alteration between Valine and Isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2
J.Biol.Chem., 285, 2010
4DNU
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CRYSTAL STRUCTURE OF THE W285A MUTANT OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNV
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CRYSTAL STRUCTURE OF THE W285F MUTANT OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4DNW
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CRYSTAL STRUCTURE OF UVB-RESISTANCE PROTEIN UVR8
Descriptor:AT5g63860/MGI19_6
Authors:Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Wang, J., Shi, Y.
Deposit date:2012-02-09
Release date:2012-03-07
Modification date:2013-07-17
Method:X-RAY DIFFRACTION (1.773 Å)
Cite:Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
4IU8
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CRYSTAL STRUCTURE OF A MEMBRANE TRANSPORTER (SELENOMETHIONINE DERIVATIVE)
Descriptor:Nitrite extrusion protein 2
Authors:Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
Deposit date:2013-01-20
Release date:2013-04-17
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
4IU9
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CRYSTAL STRUCTURE OF A MEMBRANE TRANSPORTER
Descriptor:Nitrite extrusion protein 2
Authors:Yan, H., Huang, W., Yan, C., Gong, X., Jiang, S., Zhao, Y., Wang, J., Shi, Y.
Deposit date:2013-01-20
Release date:2013-04-17
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structure and mechanism of a nitrate transporter.
Cell Rep, 3, 2013
4M57
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 FROM MAIZE
Descriptor:Chloroplast pentatricopeptide repeat protein 10
Authors:Yin, P., Li, Q., Yan, C., Liu, Y., Yan, N.
Deposit date:2013-08-08
Release date:2013-10-30
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
4M59
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 IN COMPLEX WITH AN 18-NT PSAJ RNA ELEMENT
Descriptor:Chloroplast pentatricopeptide repeat protein 10
Authors:Yin, P., Li, Q., Yan, C., Liu, Y., Yan, N.
Deposit date:2013-08-08
Release date:2013-10-30
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
4N0G
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CRYSTAL STRUCTURE OF PYL13-PP2CA COMPLEX
Descriptor:Protein phosphatase 2C 37 (E.C.3.1.3.16), Abscisic acid receptor PYL13
Authors:Li, W., Wang, L., Sheng, X., Yan, C., Zhou, R., Hang, J., Yin, P., Yan, N.
Deposit date:2013-10-01
Release date:2013-11-13
Modification date:2013-12-18
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13
Cell Res., 23, 2013
4OE1
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 (C256S/C430S/C449S) IN COMPLEX WITH AN 18-NT PSAJ RNA ELEMENT
Descriptor:Chloroplast pentatricopeptide repeat protein 10
Authors:Li, Q., Yan, C., Wu, J., Yin, P., Yan, N.
Deposit date:2014-01-11
Release date:2014-09-24
Modification date:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10).
J.Biol.Chem., 289, 2014
4OIC
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CRYSTAL STRUCTRUAL OF A SOLUBLE PROTEIN
Descriptor:Bet v I allergen-like, Probable protein phosphatase 2C 6 (E.C.3.1.3.16)
Authors:He, Y., Hao, Q., Li, W., Yan, C., Yan, N., Yin, P.
Deposit date:2014-01-19
Release date:2015-01-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Identification and characterization of ABA receptors in Oryza sativa
Plos One, 9, 2014
4RNG
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF SWEET TRANSPORTERS
Descriptor:MtN3/saliva family
Authors:Hu, Q., Wang, J., Yan, C., Yan, N.
Deposit date:2014-10-24
Release date:2014-11-19
Modification date:2014-12-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial homologue of SWEET transporters.
Cell Res., 24, 2014
4RHW
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CRYSTAL STRUCTURE OF APAF-1 CARD AND CASPASE-9 CARD COMPLEX
Descriptor:Apoptotic protease-activating factor 1, Caspase-9 (E.C.3.4.22.62)
Authors:Hu, Q., Wu, D., Yan, C., Shi, Y.
Deposit date:2014-10-03
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
Proc.Natl.Acad.Sci.USA, 2014
1S9I
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X-RAY STRUCTURE OF THE HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2 (MEK2)IN A COMPLEX WITH LIGAND AND MGATP
Descriptor:Dual specificity mitogen-activated protein kinase kinase 2 (E.C.2.7.1.-)
Authors:Ohren, J.F., Chen, H., Pavlovsky, A., Whitehead, C., Yan, C., McConnell, P., Delaney, A., Dudley, D.T., Sebolt-Leopold, J., Hasemann, C.A.
Deposit date:2004-02-04
Release date:2004-11-23
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
Nat.Struct.Mol.Biol., 11, 2004
1S9J
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X-RAY STRUCTURE OF THE HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 (MEK1) IN A COMPLEX WITH LIGAND AND MGATP
Descriptor:Dual specificity mitogen-activated protein kinase kinase 1 (E.C.2.7.1.37)
Authors:Ohren, J.F., Chen, H., Pavlovsky, A., Whitehead, C., Yan, C., McConnell, P., Delaney, A., Dudley, D.T., Sebolt-Leopold, J., Hasemann, C.A.
Deposit date:2004-02-04
Release date:2004-11-23
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
Nat.Struct.Mol.Biol., 11, 2004
5IVW
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HUMAN CORE TFIIH BOUND TO DNA WITHIN THE PIC
Descriptor:TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-21
Release date:2016-05-18
Modification date:2016-06-22
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY6
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HUMAN HOLO-PIC IN THE CLOSED STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-06-22
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY7
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HUMAN HOLO-PIC IN THE OPEN STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit RPB5, DNA-directed RNA polymerase II subunit RPB6, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit RPB8, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB12, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor TFIIS, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-06-22
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5IY8
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HUMAN HOLO-PIC IN THE INITIAL TRANSCRIBING STATE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Transcription initiation factor IIB, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, TATA-box-binding protein, General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit beta, General transcription factor IIF subunit 1, General transcription factor IIF subunit 2, Transcription elongation factor A protein 1, TFIIH basal transcription factor complex helicase XPB subunit, TFIIH basal transcription factor complex helicase XPD subunit, General transcription factor IIH subunit 2, General transcription factor IIH subunit 5, General transcription factor IIH subunit 4, General transcription factor IIH subunit 3/DNA Complex
Authors:He, Y., Yan, C., Fang, J., Inouye, C., Tjian, R., Ivanov, I., Nogales, E.
Deposit date:2016-03-24
Release date:2016-05-18
Modification date:2016-06-22
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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