7F32
 
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1LKN
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7F3N
 | | Structure of PopP2 in apo form | | Descriptor: | Type III effector protein popp2 | | Authors: | Xia, Y, Zhang, Z.M. | | Deposit date: | 2021-06-16 | | Release date: | 2021-11-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.351856 Å) | | Cite: | Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase.
Nat Commun, 12, 2021
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3CSQ
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3CT0
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7JVB
 | | Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20 | | Descriptor: | CACODYLATE ION, Nanobody Nb20, Spike protein S1 | | Authors: | Xiang, Y, Xiao, Z, Liu, H, Sang, Z, Schneidman-Duhovny, D, Zhang, C, Shi, Y. | | Deposit date: | 2020-08-20 | | Release date: | 2020-12-02 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.287 Å) | | Cite: | Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2.
Science, 370, 2020
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5XVO
 | | E. fae Cas1-Cas2/prespacer/target ternary complex revealing DNA sampling and half-integration states | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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5XVP
 | | E. fae Cas1-Cas2/prespacer/target ternary complex revealing the fully integrated states | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(P*TP*TP*CP*TP*CP*CP*GP*AP*G)-3'), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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8D6J
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8D71
 | | Human Ago2 bound to miR122(21nt) | | Descriptor: | MAGNESIUM ION, Protein argonaute-2, miR-122-21nt | | Authors: | Xiao, Y, MacRae, I. | | Deposit date: | 2022-06-07 | | Release date: | 2023-05-03 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength.
Embo Rep., 24, 2023
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5KKB
 | | Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex | | Descriptor: | 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | | Authors: | Xiang, Y, Moremen, K.W. | | Deposit date: | 2016-06-21 | | Release date: | 2016-12-07 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.774 Å) | | Cite: | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6C66
 | | CRISPR RNA-guided surveillance complex, pre-nicking | | Descriptor: | CRISPR-associated helicase, Cas3 family, CRISPR-associated protein, ... | | Authors: | Xiao, Y, Luo, M, Liao, M, Ke, A. | | Deposit date: | 2018-01-17 | | Release date: | 2018-06-27 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Science, 361, 2018
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8D50
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8D4R
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8D53
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8D0Y
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5U0A
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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5U07
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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2AMN
 | | Solution structure of Fowlicidin-1, a novel Cathelicidin antimicrobial peptide from chicken | | Descriptor: | cathelicidin | | Authors: | Xiao, Y, Dai, H, Bommineni, Y.R, Prakash, O, Zhang, G. | | Deposit date: | 2005-08-09 | | Release date: | 2006-07-18 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken.
Febs J., 273, 2006
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7SWF
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7SWQ
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7SVA
 | | Cryo-EM structure of Arabidopsis Ago10-guide RNA complex | | Descriptor: | MAGNESIUM ION, Protein argonaute 10, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') | | Authors: | Xiao, Y, MacRae, I.J. | | Deposit date: | 2021-11-18 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural basis for RNA slicing by a plant Argonaute.
Nat.Struct.Mol.Biol., 30, 2023
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8H7Q
 | | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution | | Descriptor: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | | Deposit date: | 2022-10-20 | | Release date: | 2023-10-25 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution
To Be Published
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5XVN
 | | E. far Cas1-Cas2/prespacer binary complex | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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6A5E
 | | Crystal structure of plant peptide RALF23 in complex with FER and LLG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GPI-anchored protein LLG2, ... | | Authors: | Xiao, Y, Chai, J. | | Deposit date: | 2018-06-23 | | Release date: | 2019-06-26 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.766 Å) | | Cite: | Mechanisms of RALF peptide perception by a heterotypic receptor complex.
Nature, 572, 2019
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