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2LAL
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BU of 2lal by Molmil
CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT AT 2.3 ANGSTROMS RESOLUTION OF THE LENTIL LECTIN
Descriptor: CALCIUM ION, LENTIL LECTIN (ALPHA CHAIN), LENTIL LECTIN (BETA CHAIN), ...
Authors:Loris, R, Steyaert, J, Maes, D, Lisgarten, J, Pickersgill, R, Wyns, L.
Deposit date:1993-06-10
Release date:1993-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of two crystal forms of lentil lectin at 1.8 A resolution.
Proteins, 20, 1994
4VUB
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BU of 4vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM ESCHERICHIA COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1QOS
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BU of 1qos by Molmil
lectin UEA-II complexed with chitobiose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Loris, R, De Greve, H, Dao-Thi, M.-H, Messens, J, Imberty, A, Wyns, L.
Deposit date:1999-11-16
Release date:2000-02-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Basis of Carbohydrate Recognition by Lectin II from Ulex Europaeus, a Protein with a Promiscuous Carbohydrate Binding Site
J.Mol.Biol., 301, 2000
2X6M
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BU of 2x6m by Molmil
Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein
Descriptor: ALPHA-SYNUCLEIN PEPTIDE, HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY
Authors:DeGenst, E, Guilliams, T, Wellens, J, O'Day, E.M, Waudby, C.A, Meehan, S, Dumoulin, M, Hsu, S.-T.D, Cremades, N, Verschueren, K.H.G, Pardon, E, Wyns, L, Steyaert, J, Christodoulou, J, Dobson, C.M.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
2AR6
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BU of 2ar6 by Molmil
Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, ...
Authors:Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.J, Beeckmans, S, Versees, W, Wyns, L, Loris, R.
Deposit date:2005-08-19
Release date:2006-08-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.
Febs J., 273, 2006
2AAD
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BU of 2aad by Molmil
THE ROLE OF HISTIDINE-40 IN RIBONUCLEASE T1 CATALYSIS: THREE-DIMENSIONAL STRUCTURES OF THE PARTIALLY ACTIVE HIS40LYS MUTANT
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME
Authors:Zegers, I, Verhelst, P, Choe, C.W, Steyaert, J, Heinemann, U, Wyns, L, Saenger, W.
Deposit date:1992-09-15
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
Biochemistry, 31, 1992
2AAE
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BU of 2aae by Molmil
THE ROLE OF HISTIDINE-40 IN RIBONUCLEASE T1 CATALYSIS: THREE-DIMENSIONAL STRUCTURES OF THE PARTIALLY ACTIVE HIS40LYS MUTANT
Descriptor: CALCIUM ION, PHOSPHATE ION, RIBONUCLEASE T1
Authors:Zegers, I, Verhelst, P, Choe, C.W, Steyaert, J, Heinemann, U, Wyns, L, Saenger, W.
Deposit date:1992-09-15
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
Biochemistry, 31, 1992
1QDO
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BU of 1qdo by Molmil
MAN(APLHA1-3)MAN(ALPHA1-O)METHYL CONCANAVALIN A COMPLEX
Descriptor: CALCIUM ION, MANGANESE (II) ION, PROTEIN (CONCANAVALIN A), ...
Authors:Bouckaert, J, Loris, R, Wyns, L.
Deposit date:1999-05-24
Release date:1999-10-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structures of Man(alpha1-3)Man(alpha1-O)Me and Man(alpha1-6)Man(alpha1-O)Me in complex with concanavalin A.
J.Biol.Chem., 274, 1999
5GSP
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BU of 5gsp by Molmil
RIBONUCLEASE T1/3'-GMP, 9 WEEKS
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-09
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
6GSP
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BU of 6gsp by Molmil
RIBONUCLEASE T1/3'-GMP, 15 WEEKS
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-09
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
3VUB
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BU of 3vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-17
Release date:1998-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1Q8V
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BU of 1q8v by Molmil
Pterocarpus angolensis lectin (PAL) in complex with the trimannoside [Man(Alpha1-3)]Man(alpha1-6)Man
Descriptor: CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, ...
Authors:Loris, R, Van Walle, I, De Greve, H, Beeckmans, S, Deboeck, F, Wyns, L, Bouckaert, J.
Deposit date:2003-08-22
Release date:2004-02-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Oligomannose Recognition by the Pterocarpus angolensis Seed Lectin
J.Mol.Biol., 335, 2004
1QMO
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BU of 1qmo by Molmil
Structure of FRIL, a legume lectin that delays hematopoietic progenitor maturation
Descriptor: CALCIUM ION, MANGANESE (II) ION, MANNOSE BINDING LECTIN, ...
Authors:Hamelryck, T.W, Moore, J.G, Chrispeels, M, Loris, R, Wyns, L.
Deposit date:1999-10-04
Release date:1999-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Role of Weak Protein-Protein Interactions in Multivalent Lectin-Carbohydrate Binding: Crystal Structure of Cross-Linked Fril
J.Mol.Biol., 299, 2000
1Q8S
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BU of 1q8s by Molmil
Pterocarpus angolensis lectin (PAL) in complex with the dimannoside Man(alpha1-6)Man
Descriptor: CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose-(1-6)-methyl alpha-D-mannopyranoside, ...
Authors:Loris, R, Van Walle, I, De Greve, H, Beeckmans, S, DeBoeck, F, Wyns, L, Bouckaert, J.
Deposit date:2003-08-22
Release date:2004-02-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Basis of Oligomannose Recognition by the Pterocarpus angolensis Seed Lectin
J.Mol.Biol., 335, 2004
1Q8O
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BU of 1q8o by Molmil
Pterocartpus angolensis lectin PAL in complex with the dimmanoside Man(alpha1-2)Man
Descriptor: CALCIUM ION, MANGANESE (II) ION, alpha-D-mannopyranose-(1-2)-methyl alpha-D-mannopyranoside, ...
Authors:Loris, R, Van Walle, I, De Greve, H, Beeckmans, S, Deboeck, F, Wyns, L, Bouckaert, J.
Deposit date:2003-08-22
Release date:2004-02-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Oligomannose Recognition by the Pterocarpus angolensis Seed Lectin
J.Mol.Biol., 335, 2004
4I0C
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BU of 4i0c by Molmil
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
Descriptor: CHLORIDE ION, GLYCEROL, Lysozyme C, ...
Authors:De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M.
Deposit date:2012-11-16
Release date:2013-10-09
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
7GSP
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BU of 7gsp by Molmil
RIBONUCLEASE T1/2',3'-CGPS, NON-PRODUCTIVE
Descriptor: GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, PHOSPHATE ION, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-10
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
2VUB
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BU of 2vub by Molmil
CCDB, A TOPOISOMERASE POISON FROM E. COLI
Descriptor: CCDB, CHLORIDE ION
Authors:Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L.
Deposit date:1998-04-21
Release date:1998-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
1BIR
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BU of 1bir by Molmil
RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Doumen, J, Gonciarz, M, Zegers, I, Loris, R, Wyns, L, Steyaert, J.
Deposit date:1996-01-04
Release date:1996-08-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
1BZQ
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BU of 1bzq by Molmil
COMPLEX OF A DROMEDARY SINGLE-DOMAIN VHH ANTIBODY FRAGMENT WITH RNASE A
Descriptor: PHOSPHATE ION, PROTEIN (ANTIBODY CAB-RN05), PROTEIN (RNASE A)
Authors:Decanniere, K, Desmyter, A, Gahroudhi, M, Lauwereys, M, Muyldermans, S, Wyns, L.
Deposit date:1998-11-03
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops.
Structure Fold.Des., 7, 1999
1BJQ
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BU of 1bjq by Molmil
THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH ADENINE
Descriptor: ADENINE, CALCIUM ION, LECTIN, ...
Authors:Hamelryck, T.W, Loris, R, Bouckaert, J, Dao-Thi, M.H, Wyns, L, Etzler, M.
Deposit date:1998-06-26
Release date:1998-12-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
4GSP
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BU of 4gsp by Molmil
RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS
Descriptor: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ...
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-02
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
2VCO
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BU of 2vco by Molmil
Crystal structure of the fimbrial adhesin FimH in complex with its high-mannose epitope
Descriptor: NICKEL (II) ION, PROTEIN FIMH, SULFATE ION, ...
Authors:Wellens, A, Garofalo, C, Nguyen, H, Wyns, L, De Greve, H, Hultgren, S.J, Bouckaert, J.
Deposit date:2007-09-26
Release date:2008-05-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intervening with Urinary Tract Infections Using Anti-Adhesives Based on the Crystal Structure of the Fimh-Oligomannose-3 Complex.
Plos One, 3, 2008
2X89
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BU of 2x89 by Molmil
Structure of the Beta2_microglobulin involved in amyloidogenesis
Descriptor: ANTIBODY, BETA-2-MICROGLOBULIN
Authors:Domanska, K, Srinivasan, V, Vanderhaegen, S, Pardon, E, Marquez, J.A, Bellotti, V, Wyns, L, Steyaert, J.
Deposit date:2010-03-07
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Atomic Structure of a Nanobody-Trapped Domain-Swapped Dimer of an Amyloidogenic {Beta}2-Microglobulin Variant.
Proc.Natl.Acad.Sci.USA, 108, 2011
1LEM
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BU of 1lem by Molmil
THE MONOSACCHARIDE BINDING SITE OF LENTIL LECTIN: AN X-RAY AND MOLECULAR MODELLING STUDY
Descriptor: CALCIUM ION, LECTIN, MANGANESE (II) ION, ...
Authors:Loris, R, Wyns, L.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The monosaccharide binding site of lentil lectin: an X-ray and molecular modelling study.
Glycoconj.J., 11, 1994

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