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5FCL
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CRYSTAL STRUCTURE OF CAS1 FROM PECTOBACTERIUM ATROSEPTICUM
Descriptor:CRISPR-associated endonuclease Cas1
Authors:Wilkinson, M.E., Nakatani, Y., Opel-Reading, H.K., Fineran, P.C., Krause, K.L.
Deposit date:2015-12-15
Release date:2016-03-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.
Biochem.J., 473, 2016
6EXN
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POST-CATALYTIC P COMPLEX SPLICEOSOME WITH 3' SPLICE SITE DOCKED
Descriptor:U2 snRNA, U5 snRNA, U6 snRNA, ...
Authors:Wilkinson, M.E., Fica, S.M., Galej, W.P., Norman, C.M., Newman, A.J., Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
5MPS
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, UBC4 gene exon, U2 snRNA, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-18
Release date:2017-01-18
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
5MQ0
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STRUCTURE OF A SPLICEOSOME REMODELED FOR EXON LIGATION
Descriptor:Yeast UBC4 gene for ubiquitin-conjugating enzyme, 5'-EXON OF UBC4 PRE-MRNA, S.cerevisiae chromosome II reading frame ORF YBR230c, ...
Authors:Fica, S.M., Oubridge, C., Galej, W.P., Wilkinson, M.E., Newman, A.J., Bai, X.-C., Nagai, K.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
6QDV
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HUMAN POST-CATALYTIC P COMPLEX SPLICEOSOME
Descriptor:U2 snRNA, U5 snRNA, U6 snRNA, ...
Authors:Fica, S.M., Oubridge, C., Wilkinson, M.E., Newman, A.J., Nagai, K.
Deposit date:2019-01-03
Release date:2019-02-20
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Science, 363, 2019
6QW6
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STRUCTURE OF THE HUMAN U5.U4/U6 TRI-SNRNP AT 2.9A RESOLUTION.
Descriptor:U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, U4 snRNA, Small nuclear ribonucleoprotein Sm D1, ...
Authors:Charenton, C., Wilkinson, M.E., Nagai, K.
Deposit date:2019-03-05
Release date:2019-04-17
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
6QX9
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STRUCTURE OF A HUMAN FULLY-ASSEMBLED PRECATALYTIC SPLICEOSOME (PRE-B COMPLEX).
Descriptor:U1 snRNA, U6 snRNA, U5 small nuclear ribonucleoprotein 40 kDa protein, ...
Authors:Charenton, C., Wilkinson, M.E., Nagai, K.
Deposit date:2019-03-07
Release date:2019-04-17
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
5LJ3
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STRUCTURE OF THE CORE OF THE YEAST SPLICEOSOME IMMEDIATELY AFTER BRANCHING
Descriptor:U5 snRNA (small nuclear RNA), Exon 1 (5' exon) of UBC4 pre-mRNA, Intron of UBC4 pre-mRNA, ...
Authors:Galej, W.P., Wilkinson, M.F., Fica, S.M., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-03
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5LJ5
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OVERALL STRUCTURE OF THE YEAST SPLICEOSOME IMMEDIATELY AFTER BRANCHING.
Descriptor:U5 snRNA (small nuclear RNA), Exon 1 (5' exon) of UBC4 pre-mRNA, Intron of UBC4 pre-mRNA, ...
Authors:Galej, W.P., Wilkinson, M.F., Fica, S.M., Oubridge, C., Newman, A.J., Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-31
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016